E G Severance

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Discordant patterns of bacterial translocation markers and implications for innate immune imbalances in schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Schizophr Res 148:130-7. 2013
  2. pmc Anti-gluten immune response following Toxoplasma gondii infection in mice
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 7:e50991. 2012
  3. pmc Complement C1q formation of immune complexes with milk caseins and wheat glutens in schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Neurobiol Dis 48:447-53. 2012
  4. doi request reprint Gastrointestinal inflammation and associated immune activation in schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Schizophr Res 138:48-53. 2012
  5. doi request reprint Dietary antigens, epitope recognition, and immune complex formation in recent onset psychosis and long-term schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Schizophr Res 126:43-50. 2011
  6. doi request reprint Immune activation by casein dietary antigens in bipolar disorder
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Bipolar Disord 12:834-42. 2010
  7. doi request reprint Subunit and whole molecule specificity of the anti-bovine casein immune response in recent onset psychosis and schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, United States
    Schizophr Res 118:240-7. 2010
  8. pmc Coronavirus immunoreactivity in individuals with a recent onset of psychotic symptoms
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Schizophr Bull 37:101-7. 2011
  9. doi request reprint Differentiating nicotine- versus schizophrenia-associated decreases of the alpha7 nicotinic acetylcholine receptor transcript, CHRFAM7A, in peripheral blood lymphocytes
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287 4933, USA
    J Neural Transm 116:213-20. 2009
  10. pmc Development of a nucleocapsid-based human coronavirus immunoassay and estimates of individuals exposed to coronavirus in a U.S. metropolitan population
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Clin Vaccine Immunol 15:1805-10. 2008

Detail Information

Publications12

  1. pmc Discordant patterns of bacterial translocation markers and implications for innate immune imbalances in schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Schizophr Res 148:130-7. 2013
    ..Whereas both markers may upregulate following systemic exposure to Gram-negative bacteria, non-lipopolysaccharide-based monocyte activation, autoimmunity and metabolic dysfunction may also contribute to the observed marker profiles. ..
  2. pmc Anti-gluten immune response following Toxoplasma gondii infection in mice
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 7:e50991. 2012
    ..gondii infection and sensitivity to dietary gluten, might be connected to produce the immune activation that is becoming an increasingly recognized pathology of psychiatric disorders...
  3. pmc Complement C1q formation of immune complexes with milk caseins and wheat glutens in schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Neurobiol Dis 48:447-53. 2012
    ..Future prospective studies should evaluate the impacts of casein- and gluten-free diets on C1q activation in schizophrenia...
  4. doi request reprint Gastrointestinal inflammation and associated immune activation in schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Schizophr Res 138:48-53. 2012
    ....
  5. doi request reprint Dietary antigens, epitope recognition, and immune complex formation in recent onset psychosis and long-term schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Schizophr Res 126:43-50. 2011
    ....
  6. doi request reprint Immune activation by casein dietary antigens in bipolar disorder
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Bipolar Disord 12:834-42. 2010
    ..We tested whether antibodies to bovine milk caseins were associated with bipolar disorder, and whether patients recognized different epitopes of the casein protein than control individuals...
  7. doi request reprint Subunit and whole molecule specificity of the anti-bovine casein immune response in recent onset psychosis and schizophrenia
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, United States
    Schizophr Res 118:240-7. 2010
    ..The elevated IgG and unique patterns of antibody specificity to bovine casein among diagnostic groups provide a rationale for clinical trials to evaluate efficacies of dietary modifications in individuals with neuropsychiatric diseases...
  8. pmc Coronavirus immunoreactivity in individuals with a recent onset of psychotic symptoms
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Schizophr Bull 37:101-7. 2011
    ..Future studies should explore links between the timing of coronavirus infections and subsequent development of schizophrenia and other disorders with psychotic symptoms...
  9. doi request reprint Differentiating nicotine- versus schizophrenia-associated decreases of the alpha7 nicotinic acetylcholine receptor transcript, CHRFAM7A, in peripheral blood lymphocytes
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287 4933, USA
    J Neural Transm 116:213-20. 2009
    ..03), and not when smoking was self-reported. Including biochemical indicators of serum nicotine can help differentiate smoking- versus disease-associated changes in nAChR expression...
  10. pmc Development of a nucleocapsid-based human coronavirus immunoassay and estimates of individuals exposed to coronavirus in a U.S. metropolitan population
    Emily G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Clin Vaccine Immunol 15:1805-10. 2008
    ..Demographic factors, such as race, smoking status, and socioeconomic status, may confer an increased risk of susceptibility to these viruses...
  11. ncbi request reprint Lack of RIC-3 congruence with beta2 subunit-containing nicotinic acetylcholine receptors in bipolar disorder
    E G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Blalock 1105, Baltimore, MD 21287 4933, USA
    Neuroscience 148:454-60. 2007
    ....
  12. ncbi request reprint Novel alpha7 nicotinic receptor isoforms and deficient cholinergic transcription in schizophrenia
    E G Severance
    Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1105, Baltimore, MD21287 4933, USA
    Genes Brain Behav 7:37-45. 2008
    ..Our data demonstrate that alpha7 transcription is altered in several ways in SZ, suggesting that transcription-level mechanisms could account in part for the impaired cholinergic neurotransmission observed in this disease...