R D Semba

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Vitamin A levels and human immunodeficiency virus load in injection drug users
    R D Semba
    Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Clin Diagn Lab Immunol 4:93-5. 1997
  2. ncbi Vitamin A as "anti-infective" therapy, 1920-1940
    R D Semba
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Nutr 129:783-91. 1999
  3. ncbi Micronutrients and the pathogenesis of human immunodeficiency virus infection
    R D Semba
    Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Br J Nutr 81:181-9. 1999
  4. ncbi Improvement of anemia among HIV-infected injection drug users receiving highly active antiretroviral therapy
    R D Semba
    Department of Ophthalmology, Schools of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    J Acquir Immune Defic Syndr 26:315-9. 2001
  5. ncbi Human immunodeficiency virus load in breast milk, mastitis, and mother-to-child transmission of human immunodeficiency virus type 1
    R D Semba
    Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    J Infect Dis 180:93-8. 1999
  6. ncbi Iron status and indicators of human immunodeficiency virus disease severity among pregnant women in Malawi
    R D Semba
    Department of Ophthalmology, Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, MD 21205, USA
    Clin Infect Dis 32:1496-9. 2001
  7. ncbi Serum carotenoids and pulmonary function in older community-dwelling women
    R D Semba
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Nutr Health Aging 16:291-6. 2012
  8. ncbi Effect of antibiotic treatment of subclinical mastitis on human immunodeficiency virus type 1 RNA in human milk
    V Nussenblatt
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Trop Pediatr 52:311-5. 2006
  9. ncbi Assessment of iron status using plasma transferrin receptor in pregnant women with and without human immunodeficiency virus infection in Malawi
    R D Semba
    Departments of Ophthalmology and Epidemiology, Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, Maryland, USA
    Eur J Clin Nutr 54:872-7. 2000
  10. ncbi Mastitis and immunological factors in breast milk of lactating women in Malawi
    R D Semba
    Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Clin Diagn Lab Immunol 6:671-4. 1999

Collaborators

Detail Information

Publications43

  1. ncbi Vitamin A levels and human immunodeficiency virus load in injection drug users
    R D Semba
    Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Clin Diagn Lab Immunol 4:93-5. 1997
    ..HIV-infected adult women appear to be at higher risk of developing vitamin A deficiency...
  2. ncbi Vitamin A as "anti-infective" therapy, 1920-1940
    R D Semba
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Nutr 129:783-91. 1999
    ..Recent controlled clinical trials of vitamin A from the last 15 y follow a tradition of investigation that began largely in the 1920s...
  3. ncbi Micronutrients and the pathogenesis of human immunodeficiency virus infection
    R D Semba
    Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Br J Nutr 81:181-9. 1999
    ....
  4. ncbi Improvement of anemia among HIV-infected injection drug users receiving highly active antiretroviral therapy
    R D Semba
    Department of Ophthalmology, Schools of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    J Acquir Immune Defic Syndr 26:315-9. 2001
    ..HAART was associated with an improvement in anemia, and potential mechanisms that may be involved include a reduction in opportunistic infections and the anemia of chronic disease and an improvement in nutritional status...
  5. ncbi Human immunodeficiency virus load in breast milk, mastitis, and mother-to-child transmission of human immunodeficiency virus type 1
    R D Semba
    Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    J Infect Dis 180:93-8. 1999
    ..0001). Mastitis and breast milk HIV-1 load may increase the risk of vertical transmission of HIV-1 through breast-feeding...
  6. ncbi Iron status and indicators of human immunodeficiency virus disease severity among pregnant women in Malawi
    R D Semba
    Department of Ophthalmology, Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, MD 21205, USA
    Clin Infect Dis 32:1496-9. 2001
    ..In contrast to previous studies, these data suggest that iron status is not related to markers of HIV disease severity in pregnant women in Africa...
  7. ncbi Serum carotenoids and pulmonary function in older community-dwelling women
    R D Semba
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Nutr Health Aging 16:291-6. 2012
    ..Serum carotenoids are considered the most reliable indicator of fruit and vegetable intake...
  8. ncbi Effect of antibiotic treatment of subclinical mastitis on human immunodeficiency virus type 1 RNA in human milk
    V Nussenblatt
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Trop Pediatr 52:311-5. 2006
    ..These findings have important implications regarding how mothers should be counselled on safety of resuming breastfeeding after resolution of subclinical mastitis...
  9. ncbi Assessment of iron status using plasma transferrin receptor in pregnant women with and without human immunodeficiency virus infection in Malawi
    R D Semba
    Departments of Ophthalmology and Epidemiology, Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, Maryland, USA
    Eur J Clin Nutr 54:872-7. 2000
    ..Although anemia is highly prevalent during pregnancy and is common during human immunodeficiency virus (HIV) infection, anemia and iron status have not been well characterized in HIV-infected pregnant women...
  10. ncbi Mastitis and immunological factors in breast milk of lactating women in Malawi
    R D Semba
    Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Clin Diagn Lab Immunol 6:671-4. 1999
    ..0001); and RANTES, 82 versus 3 ng/liter (P < 0.0001). Elevated sodium concentrations in breast milk are associated with an increase in levels of some immunological and inflammatory factors in breast milk...
  11. ncbi Diet quality and social support: factors associated with serum carotenoid concentrations among older disabled women (the Women's Health and Aging Study)
    E J Nicklett
    Johns Hopkins University, Center on Aging and Health, Baltimore, MD 21231, USA
    J Nutr Health Aging 16:511-8. 2012
    ..This study investigated the relationship between social support (including instrumental support, emotional support, social interaction, social space, and family networks) and diet quality, as indicated by serum carotenoid levels...
  12. ncbi Low serum selenium is associated with anemia among older adults in the United States
    R D Semba
    The Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    Eur J Clin Nutr 63:93-9. 2009
    ..We hypothesized that low serum selenium was associated with anemia in humans...
  13. ncbi Impact of vitamin A supplementation on anaemia and plasma erythropoietin concentrations in pregnant women: a controlled clinical trial
    R D Semba
    Department of Ophthalmology, and Center for Human Nutrition, The Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, Maryland, USA
    Eur J Haematol 66:389-95. 2001
    ..Although studies suggest that vitamin A or its metabolites influence the synthesis of erythropoietin in vitro and in animal models, it is unclear whether vitamin A supplementation increases plasma erythropoietin concentrations in humans...
  14. ncbi Markers of B-vitamin deficiency and frailty in older women
    A M Matteini
    Johns Hopkins Institutions, Baltimore, MD, USA
    J Nutr Health Aging 12:303-8. 2008
    ..To evaluate the association between markers of vitamins B12, B6 and folate deficiency and the geriatric syndrome of frailty...
  15. ncbi Malnutrition and morbidity among children not reached by the national vitamin A capsule programme in urban slum areas of Indonesia
    S G Berger
    Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Public Health 122:371-8. 2008
    ..Although it has been suggested that there are health disparities between children who are reached or not reached by these programmes, little quantitative work has been undertaken to characterize this relationship...
  16. ncbi Relation of vitamin A and carotenoid status to growth failure and mortality among Ugandan infants with human immunodeficiency virus
    G Melikian
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Nutrition 17:567-72. 2001
    ..16, 95% confidence interval: 1.38 to 7.21, P < 0.006). These data suggest that low concentrations of plasma carotenoids are associated with increased risk of death during HIV infection among infants in Uganda...
  17. ncbi Vitamin D deficiency among older women with and without disability
    R D Semba
    Johns Hopkins Medical Institutions, Baltimore, and the Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, MD, USA
    Am J Clin Nutr 72:1529-34. 2000
    ..Vitamin D deficiency is associated with bone loss and bone fractures, and the identification of vulnerable populations is important to clinical practice and public health...
  18. ncbi Low plasma selenium concentrations, high plasma human immunodeficiency virus load and high interleukin-6 concentrations are risk factors associated with anemia in adults presenting with pulmonary tuberculosis in Zomba district, Malawi
    M Van Lettow
    Johns Hopkins University School of Medicine, Baltimore, USA
    Eur J Clin Nutr 59:526-32. 2005
    ..Although anemia is common among adults with pulmonary tuberculosis and human immunodeficiency virus (HIV) infection in sub-Saharan Africa, the factors contributing to its pathogenesis have not been well characterized...
  19. ncbi Low serum carotenoids are associated with a decline in walking speed in older women
    N Alipanah
    Johns Hopkins Medical Institutions, Baltimore, MD, USA
    J Nutr Health Aging 13:170-5. 2009
    ..The aim was to determine whether total serum carotenoid concentrations, a marker for fruit and vegetable intake, and serum selenium are related to changes in walking speed in older women...
  20. ncbi Denture use, malnutrition, frailty, and mortality among older women living in the community
    R D Semba
    The Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    J Nutr Health Aging 10:161-7. 2006
    ..The relationships between denture use, malnutrition, frailty, and mortality in older women have not been well characterized...
  21. ncbi Highly active antiretroviral therapy associated with improved anemia among HIV-infected women
    R D Semba
    Department of Ophthalmology, Department of Epidemiology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    AIDS Patient Care STDS 15:473-80. 2001
    ..01), whereas there was no significant change in the prevalence of anemia among those on non-HAART ART or those who had no reported treatment. HAART is associated with a large reduction in anemia among HIV-infected women...
  22. ncbi Relationship of household food insecurity to anaemia in children aged 6-59 months among families in rural Indonesia
    A A Campbell
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Ann Trop Paediatr 31:321-30. 2011
    ..Household food insecurity, which reflects a household's access, availability and utilisation of food, has not been well characterised in relation to anaemia in children...
  23. ncbi Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial
    A H Shankar
    Department of International Health, Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland 21205, USA
    Lancet 354:203-9. 1999
    ..Vitamin A is central to normal immune function, and supplementation has been shown to lower the morbidity of some infectious diseases. We investigated the effect of vitamin A supplementation on malaria morbidity...
  24. ncbi Hyporetinolemia and acute phase proteins in children with and without xerophthalmia
    R D Semba
    Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Am J Clin Nutr 72:146-53. 2000
    ..The relations among hyporetinolemia, acute phase proteins, and vitamin A status in children are unclear...
  25. ncbi Measles infection in HIV-infected African infants
    R T Perry
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Ann N Y Acad Sci 918:377-80. 2000
    ..In the context of the HIV epidemic, further work is needed to determine the risk of measles and its complications in HIV-positive infants and the optimal age of measles immunization...
  26. ncbi Serum antioxidants, inflammation, and total mortality in older women
    J Walston
    School of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Am J Epidemiol 163:18-26. 2006
    ..54, 95% confidence interval: 1.03, 2.32). These findings suggest that specific antioxidant nutrients may play an important role in suppressing IL-6 levels in disabled older women...
  27. ncbi Relationship of 25-hydroxyvitamin D with all-cause and cardiovascular disease mortality in older community-dwelling adults
    R D Semba
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Eur J Clin Nutr 64:203-9. 2010
    ..We hypothesized that low serum 25(OH)D levels predicted mortality in older adults...
  28. ncbi Integration of vitamin A supplementation with the Expanded Programme on Immunization: lack of impact on morbidity or infant growth
    R D Semba
    Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Acta Paediatr 90:1107-11. 2001
    ....
  29. ncbi Epidemiology and microbiology of subclinical mastitis among HIV-infected women in Malawi
    V Nussenblatt
    Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Int J STD AIDS 16:227-32. 2005
    ..02). Subclinical mastitis is prevalent among breastfeeding mothers and further studies are needed to characterize the differences between infectious and non-infectious subclinical mastitis...
  30. ncbi Dietary intake associated with serum versus urinary carboxymethyl-lysine, a major advanced glycation end product, in adults: the Energetics Study
    R D Semba
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Eur J Clin Nutr 66:3-9. 2012
    ..The objective was to describe dietary intake, the dominant source of exposure to AGEs, with carboxymethyl-lysine (CML), a major AGE, in serum and urine, respectively...
  31. ncbi Paternal smoking and increased risk of child malnutrition among families in rural Indonesia
    C M Best
    The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Tob Control 17:38-45. 2008
    ..To determine whether paternal smoking is associated with an increased risk of child malnutrition among families in rural Indonesia...
  32. ncbi Micronutrient supplements and mortality of HIV-infected adults with pulmonary TB: a controlled clinical trial
    R D Semba
    Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Int J Tuberc Lung Dis 11:854-9. 2007
    ..Zomba and Blantyre, Malawi, Africa...
  33. ncbi Vitamin A and immunity to viral, bacterial and protozoan infections
    R D Semba
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Nutr Soc 58:719-27. 1999
    ..Immune responses vary considerably during different infections, and the available data suggest that the modulation of immune function by vitamin A may also vary widely, depending on the type of infection and immune responses involved...
  34. ncbi Long-term outcome in patients registered with tuberculosis in Zomba, Malawi: mortality at 7 years according to initial HIV status and type of TB
    A D Harries
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Int J Tuberc Lung Dis 8:829-36. 2004
    ..3-2.0) were higher than in patients with smear-positive PTB. CONCLUSIONS: There was a high mortality rate in TB patients during and after anti-tuberculosis treatment. Adjunctive treatments to reduce death rates are urgently needed...
  35. ncbi Relationship of a dominant advanced glycation end product, serum carboxymethyl-lysine, and abnormal glucose metabolism in adults: the Baltimore Longitudinal Study of Aging
    R D Semba
    Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    J Nutr Health Aging 14:507-13. 2010
    ..We investigated the relationship between a dominant serum AGE, N-carboxymethyl-lysine (CML), and glucose metabolism...
  36. ncbi Anemia and interleukin-10, tumor necrosis factor alpha, and erythropoietin levels among children with acute, uncomplicated Plasmodium falciparum malaria
    V Nussenblatt
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Clin Diagn Lab Immunol 8:1164-70. 2001
    ..Further studies are needed to understand the relationships between age-related immune responses to malaria and their role in the pathogenesis of malarial anemia...
  37. ncbi Iron supplementation during human immunodeficiency virus infection: a double-edged sword?
    T D Clark
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Med Hypotheses 57:476-9. 2001
    ..The available data do not contraindicate the current practice of iron supplementation in developing countries where there is a high prevalence of both HIV infection and iron deficiency...
  38. ncbi Assessment of vitamin A status of preschool children in Indonesia using plasma retinol-binding protein
    R D Semba
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Trop Pediatr 48:84-7. 2002
    ..Measurement of plasma RBP by radial immunodiffusion is simple and inexpensive, and this test can be used as a simple surrogate measure for vitamin A concentrations in large field studies...
  39. ncbi Malnutrition and the severity of lung disease in adults with pulmonary tuberculosis in Malawi
    M Van Lettow
    Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Int J Tuberc Lung Dis 8:211-7. 2004
    ..CONCLUSION: The severity of lung disease in adults with PTB is associated with the extent of malnutrition, as reflected by BMI and body composition studies using bioelectrical impedance analysis...
  40. ncbi Coverage of the vitamin A supplementation programme for child survival in Nepal: success and challenges
    A M Nguyen
    Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Paediatr Int Child Health 32:233-8. 2012
    ..Nepal's national vitamin A programme, which began in 1993 and continues twice yearly, targets pre-school-aged children in all districts of the country in an effort to reduce morbidity, mortality and nutritional blindness...
  41. ncbi Iodine in human milk: perspectives for infant health
    R D Semba
    Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Nutr Rev 59:269-78. 2001
    ..Further studies of human milk iodine are needed to ensure that iodine prophylaxis is providing sufficient iodine for mothers and infants worldwide...
  42. ncbi Risk factors for nightblindness among women of childbearing age in Cambodia
    R D Semba
    Department of Ophthalmology, Johns Hopkins School of Medicine, 550 North Broadway, Suite 700, Baltimore, MD 21205, USA
    Eur J Clin Nutr 57:1627-32. 2003
    ..To characterize risk factors for nightblindness among nonpregnant women of childbearing age, a group recently recognized to be at high risk of vitamin A deficiency in some developing countries...
  43. ncbi Are lutein and zeaxanthin conditionally essential nutrients for eye health?
    R D Semba
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Med Hypotheses 61:465-72. 2003
    ....