Alan L Scott

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. ncbi Filarial and Wolbachia genomics
    A L Scott
    Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MA 21205, USA
    Parasite Immunol 34:121-9. 2012
  2. ncbi The genome of Brugia malayi - all worms are not created equal
    Alan L Scott
    Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Parasitol Int 58:6-11. 2009
  3. ncbi Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons
    Kiwon Park
    The W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Leukoc Biol 88:1081-7. 2010
  4. ncbi Hookworm-induced persistent changes to the immunological environment of the lung
    Joshua J Reece
    Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Infect Immun 76:3511-24. 2008
  5. ncbi Neonatal sex steroids affect responses to Seoul virus infection in male but not female Norway rats
    Sabra L Klein
    The W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205 2179, USA
    Brain Behav Immun 16:736-46. 2002
  6. ncbi Differential expression of immunoregulatory genes in male and female Norway rats following infection with Seoul virus
    Sabra L Klein
    W Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    J Med Virol 74:180-90. 2004
  7. ncbi Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages
    Joshua J Reece
    W.H. Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Infect Immun 74:4970-81. 2006
  8. ncbi Involvement of gonadal steroids and gamma interferon in sex differences in response to blood-stage malaria infection
    Amy Cernetich
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe St, Baltimore, MD 21205 2179, USA
    Infect Immun 74:3190-203. 2006
  9. ncbi Mycobacterium-induced potentiation of type 1 immune responses and protection against malaria are host specific
    Kathleen R Page
    Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Infect Immun 73:8369-80. 2005
  10. ncbi Global gene expression analysis of Anopheles gambiae responses to microbial challenge
    Ruth Aguilar
    W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205-2179, USA
    Insect Biochem Mol Biol 35:709-19. 2005

Research Grants

  1. APPLIED GENOMICS IN CARDIOPULMONARY DISEASE
    Alan Scott; Fiscal Year: 2003

Collaborators

Detail Information

Publications13

  1. ncbi Filarial and Wolbachia genomics
    A L Scott
    Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MA 21205, USA
    Parasite Immunol 34:121-9. 2012
    ..The goal here is to provide an overview of the trends and advances in filarial and Wolbachia genomics...
  2. ncbi The genome of Brugia malayi - all worms are not created equal
    Alan L Scott
    Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Parasitol Int 58:6-11. 2009
    ..The goal of this review is to provide an overview of the results of genomic analysis and how these observations provide new insights into the biology of filarial species...
  3. ncbi Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons
    Kiwon Park
    The W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Leukoc Biol 88:1081-7. 2010
    ....
  4. ncbi Hookworm-induced persistent changes to the immunological environment of the lung
    Joshua J Reece
    Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Infect Immun 76:3511-24. 2008
    ....
  5. ncbi Neonatal sex steroids affect responses to Seoul virus infection in male but not female Norway rats
    Sabra L Klein
    The W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205 2179, USA
    Brain Behav Immun 16:736-46. 2002
    ..Neonatal sex steroids influence the sexual dimorphism in host immune function but do not modify virus replication in target tissues...
  6. ncbi Differential expression of immunoregulatory genes in male and female Norway rats following infection with Seoul virus
    Sabra L Klein
    W Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    J Med Virol 74:180-90. 2004
    ..g., hsp70) suggesting that cellular stress is elevated in males. These data provide candidate genes and cellular pathways that may underlie sex differences in responses to Seoul virus and possibly other hemorrhagic fever viruses...
  7. ncbi Innate immune responses to lung-stage helminth infection induce alternatively activated alveolar macrophages
    Joshua J Reece
    W.H. Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Infect Immun 74:4970-81. 2006
    ....
  8. ncbi Involvement of gonadal steroids and gamma interferon in sex differences in response to blood-stage malaria infection
    Amy Cernetich
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe St, Baltimore, MD 21205 2179, USA
    Infect Immun 74:3190-203. 2006
    ..These data suggest that differential transcription and translation of IFN-gamma, that is influenced by estrogens, may mediate sex differences in response to malaria...
  9. ncbi Mycobacterium-induced potentiation of type 1 immune responses and protection against malaria are host specific
    Kathleen R Page
    Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Infect Immun 73:8369-80. 2005
    ..yoelii 17XL. These data indicate that M. tuberculosis-induced potentiation of type 1 immune responses is associated with protection against lethal murine malaria...
  10. ncbi Global gene expression analysis of Anopheles gambiae responses to microbial challenge
    Ruth Aguilar
    W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205-2179, USA
    Insect Biochem Mol Biol 35:709-19. 2005
    ....
  11. ncbi Dynamics of lung macrophage activation in response to helminth infection
    Mark C Siracusa
    The W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
    J Leukoc Biol 84:1422-33. 2008
    ..These data indicate that the alternative activation of macrophages in the lungs, although initiated by IL-4/IL-13, is a dynamic process that is likely to be influenced by other immune and nonimmune factors in the pulmonary environment...
  12. ncbi MSP domain proteins show enhanced expression in male germ line cells
    D E K Tarr
    The W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Mol Biochem Parasitol 137:87-98. 2004
    ..The 23 members of the MDP family of proteins from C. elegans were predicted to be transcribed in the testis. The findings provide additional candidates to the growing list of molecules that regulate MSP cytoskeletal dynamics...
  13. ncbi Common and divergent immune response signaling pathways discovered in peripheral blood mononuclear cell gene expression patterns in presymptomatic and clinically apparent malaria
    Christian F Ockenhouse
    Division of Communicable Disease and Immunology, Walter Reed Army Institute of Research, Silver Spring, MD 20910
    Infect Immun 74:5561-73. 2006
    ....

Research Grants1

  1. APPLIED GENOMICS IN CARDIOPULMONARY DISEASE
    Alan Scott; Fiscal Year: 2003
    ..The combined (mouse and human) approach of this program to the identification of disease specific genes for lung and cardiac remodeling should greatly facilitate future disease discovery. ..