Steven P Schulman

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Effects of acute hormone therapy on recurrent ischemia in postmenopausal women with unstable angina
    Steven P Schulman
    Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Am Coll Cardiol 39:231-7. 2002
  2. ncbi request reprint L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial
    Steven P Schulman
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, USA
    JAMA 295:58-64. 2006
  3. pmc Abnormalities in arterial-ventricular coupling in older healthy persons are attenuated by sodium nitroprusside
    Paul D Chantler
    Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    Am J Physiol Heart Circ Physiol 300:H1914-22. 2011
  4. pmc Use of the Frank-Starling mechanism during exercise is linked to exercise-induced changes in arterial load
    Paul D Chantler
    Intramural Research Program, National Institute on Aging, Baltimore, Maryland 21225, USA
    Am J Physiol Heart Circ Physiol 302:H349-58. 2012
  5. pmc The sex-specific impact of systolic hypertension and systolic blood pressure on arterial-ventricular coupling at rest and during exercise
    Paul D Chantler
    Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21225, USA
    Am J Physiol Heart Circ Physiol 295:H145-53. 2008
  6. ncbi request reprint Response to catecholamine stimulation of polymorphisms of the beta-1 and beta-2 adrenergic receptors
    Rhondalyn C McLean
    Division of Cardiology, Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
    Am J Cardiol 110:1001-7. 2012
  7. pmc Reduced myocardial creatine kinase flux in human myocardial infarction: an in vivo phosphorus magnetic resonance spectroscopy study
    Paul A Bottomley
    Division of MR Research, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Circulation 119:1918-24. 2009
  8. ncbi request reprint Antiplatelet therapy in non-ST-segment elevation acute coronary syndromes
    Steven P Schulman
    Coronary Care Unit, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    JAMA 292:1875-82. 2004
  9. ncbi request reprint Neurohumoral features of myocardial stunning due to sudden emotional stress
    Ilan S Wittstein
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, USA
    N Engl J Med 352:539-48. 2005
  10. pmc Effects of aspirin responsiveness and platelet reactivity on early vein graft thrombosis after coronary artery bypass graft surgery
    Tyler J Gluckman
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    J Am Coll Cardiol 57:1069-77. 2011

Detail Information

Publications30

  1. ncbi request reprint Effects of acute hormone therapy on recurrent ischemia in postmenopausal women with unstable angina
    Steven P Schulman
    Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Am Coll Cardiol 39:231-7. 2002
    ..We tested whether acute hormone therapy reduces ambulatory electrocardiographic ischemia in postmenopausal (PMP) women with unstable angina (UA)...
  2. ncbi request reprint L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial
    Steven P Schulman
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, USA
    JAMA 295:58-64. 2006
    ..The amino acid L-arginine is a substrate for nitric oxide synthase and is increasingly used as a health supplement. Prior studies suggest that L-arginine has the potential to reduce vascular stiffness...
  3. pmc Abnormalities in arterial-ventricular coupling in older healthy persons are attenuated by sodium nitroprusside
    Paul D Chantler
    Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    Am J Physiol Heart Circ Physiol 300:H1914-22. 2011
    ..This is relevant to common conditions in older subjects associated with a significant impairment of exercise performance such as frailty or heart failure with preserved ejection fraction...
  4. pmc Use of the Frank-Starling mechanism during exercise is linked to exercise-induced changes in arterial load
    Paul D Chantler
    Intramural Research Program, National Institute on Aging, Baltimore, Maryland 21225, USA
    Am J Physiol Heart Circ Physiol 302:H349-58. 2012
    ..These findings provide interesting insights into the dynamic cardiovascular alterations during exercise...
  5. pmc The sex-specific impact of systolic hypertension and systolic blood pressure on arterial-ventricular coupling at rest and during exercise
    Paul D Chantler
    Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21225, USA
    Am J Physiol Heart Circ Physiol 295:H145-53. 2008
    ..Whether a smaller E(a)I/E(LV)I reserve leads to functional limitations warrants further examination...
  6. ncbi request reprint Response to catecholamine stimulation of polymorphisms of the beta-1 and beta-2 adrenergic receptors
    Rhondalyn C McLean
    Division of Cardiology, Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
    Am J Cardiol 110:1001-7. 2012
    ..In conclusion, β-receptor gene variants significantly influence inotropic and chronotropic responses to β-agonist exposure in patients on β-blocker therapy...
  7. pmc Reduced myocardial creatine kinase flux in human myocardial infarction: an in vivo phosphorus magnetic resonance spectroscopy study
    Paul A Bottomley
    Division of MR Research, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Circulation 119:1918-24. 2009
    ..CK flux is defined as the product of [PCr] and k. CK flux and k have never been measured in human MI...
  8. ncbi request reprint Antiplatelet therapy in non-ST-segment elevation acute coronary syndromes
    Steven P Schulman
    Coronary Care Unit, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    JAMA 292:1875-82. 2004
    ..Recognition that there is a great deal of interpatient variability in response to these antiplatelet therapies highlights the need for future research in this area...
  9. ncbi request reprint Neurohumoral features of myocardial stunning due to sudden emotional stress
    Ilan S Wittstein
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, USA
    N Engl J Med 352:539-48. 2005
    ..Reversible left ventricular dysfunction precipitated by emotional stress has been reported, but the mechanism remains unknown...
  10. pmc Effects of aspirin responsiveness and platelet reactivity on early vein graft thrombosis after coronary artery bypass graft surgery
    Tyler J Gluckman
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    J Am Coll Cardiol 57:1069-77. 2011
    ..The purpose of this study was to determine if an incomplete response to or inadequate antiplatelet effect of aspirin, or both, contribute to saphenous vein graft (SVG) occlusion after coronary artery bypass graft (CABG) surgery...
  11. ncbi request reprint Prospective evaluation of the relationship between platelet-leukocyte conjugate formation and recurrent myocardial ischemia in patients with acute coronary syndromes
    Nauder Faraday
    Division of Cardiac Surgical Intensive Care, Department of Anesthesiology adn Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Platelets 15:9-14. 2004
    ..84, P < 0.05). TRAP induced platelet-neutrophil conjugate formation is related to in vivo ischemic risk in ACS patients...
  12. pmc Altered creatine kinase adenosine triphosphate kinetics in failing hypertrophied human myocardium
    Craig S Smith
    Department of Medicine, Cardiology Division, The Johns Hopkins Hospital, Baltimore, MD 21287 6568, USA
    Circulation 114:1151-8. 2006
    ..The progression of pressure-overload left ventricular hypertrophy (LVH) to chronic heart failure (CHF) may involve a relative deficit in energy supply and/or delivery...
  13. ncbi request reprint A simplified approach to the management of non-ST-segment elevation acute coronary syndromes
    Ty J Gluckman
    Division of Cardiology, The Johns Hopkins Hospital, Baltimore, MD, USA
    JAMA 293:349-57. 2005
    ..While current practice guidelines provide an evidence-based approach to management of acute coronary syndromes (ACS), application of the evidence by individual physicians has been suboptimal...
  14. ncbi request reprint Effect of short-term estrogen with and without progesterone therapy on circulating markers of endothelial activation and injury in postmenopausal women with unstable angina pectoris
    Eric T Chou
    Division of Cardiology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    Am J Cardiol 91:1240-2. 2003
  15. ncbi request reprint Effects of a pharmacologically-induced shift of hemoglobin-oxygen dissociation on myocardial energetics during ischemia in patients with coronary artery disease
    Samer S Najjar
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    J Cardiovasc Magn Reson 7:657-66. 2005
    ..We evaluated whether exercise-induced myocardial ischemia can be alleviated in subjects with coronary artery disease (CAD) by enhancing oxygen release with an allosteric modifier of hemoglobin's affinity for oxygen (RSR13)...
  16. doi request reprint Polymorphisms of the beta adrenergic receptor predict left ventricular remodeling following acute myocardial infarction
    Rhondalyn C McLean
    Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Cardiovasc Drugs Ther 25:251-8. 2011
    ..This study was undertaken to explore the relationship between LV remodeling after myocardial infarction and polymorphisms in the cardiac β1-AR and β2-AR genes...
  17. ncbi request reprint Pathogenesis and early management of non-ST-segment elevation acute coronary syndromes
    Tomas H Ayala
    Division of Cardiology, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Cardiol Clin 24:19-35. 2006
    ....
  18. ncbi request reprint Incidence of antiplatelet factor 4/heparin antibody induction in patients undergoing percutaneous coronary revascularization
    Tyler J Gluckman
    Department of Medicine Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    Am J Cardiol 95:744-7. 2005
    ..Correlations were then made across antibody induction, heparin exposure, and clinical outcome at 6 months...
  19. ncbi request reprint Age and gender affect ventricular-vascular coupling during aerobic exercise
    Samer S Najjar
    Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, Maryland 21224, USA
    J Am Coll Cardiol 44:611-7. 2004
    ....
  20. ncbi request reprint Postoperative ventricular function and cardiac enzymes after on-pump versus off-pump CABG surgery
    Patricia P Chang
    Department of From the Departments of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 89:1107-10. 2002
  21. ncbi request reprint Age-related vascular stiffness and left ventricular size after myocardial infarction
    Glenn A Hirsch
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Geriatr Cardiol 16:222-8. 2007
    ..02) were significant predictors of end-systolic volume index. Older patients have increased LV size after MI compared with younger patients, possibly related to age-related decreases in aortic distensibility affecting LV remodeling...
  22. doi request reprint Troponin-I elevation in a young man with arrhythmogenic right ventricular dysplasia/cardiomyopathy
    William J Kostis
    Department of Medicine, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Interv Card Electrophysiol 22:49-53. 2008
    ..The patient was successfully treated with radiofrequency ablation. This case illustrates that ARVD/C may result in elevated cardiac enzymes in the absence of coronary artery disease...
  23. ncbi request reprint Intensive care after resuscitation from cardiac arrest: a focus on heart and brain injury
    Steven P Schulman
    Department of Medicine Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Neurol Clin 24:41-59, vi. 2006
    ..This article addresses the acute care, with emphasis on the cardiac and neurologic aspects,that patients who have post cardiac arrest are provided in the cardiac ICU...
  24. ncbi request reprint Images in cardiovascular medicine. ST-segment elevation in an unresponsive patient
    Glenn A Hirsch
    Division of Cardiology, Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD, USA
    Circulation 108:e165-6. 2003
  25. doi request reprint Familial hypertrophic cardiomyopathy associated with cardiac beta-myosin heavy chain and troponin I mutations
    Aisha Frazier
    Department of Pediatrics, Cardiology Division, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA
    Pediatr Cardiol 29:846-50. 2008
    ....
  26. ncbi request reprint Interaction of hemostatic genetics with hormone therapy: new insights to explain arterial thrombosis in postmenopausal women
    Joel B Braunstein
    The Johns Hopkins Ciccarone Center for Prevention of Heart Disease, Divsion of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Chest 121:906-20. 2002
    ..Genetic profiling has great potential to improve the safety and efficacy of individualized pharmacotherapy in postmenopausal women and other at-risk populations for the prevention of cardiovascular disease...
  27. ncbi request reprint Cardiac Stem Cell Therapy. Need for Optimization of Efficacy and Safety Monitoring
    Peter Oettgen
    Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
    Circulation 114:353-8. 2006
  28. doi request reprint Race, medical researcher distrust, perceived harm, and willingness to participate in cardiovascular prevention trials
    Joel B Braunstein
    Center for Outcomes Research and Evaluation, Yale School of Medicine, New Haven, Connecticut, USA
    Medicine (Baltimore) 87:1-9. 2008
    ..These factors, in turn, appear to explain much of the resistance among African American persons to participate in clinical trials compared to white persons...
  29. ncbi request reprint The value of clopidogrel administered postoperatively following a non-ST-segment elevation acute coronary syndrome
    Ty J Gluckman
    Chest 127:2297. 2005
  30. doi request reprint A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation in patients with systolic heart failure: rationale, design, and baseline patient characteristics
    William T Abraham
    The Ohio State University Heart Center, Division of Cardiovascular Medicine, Columbus, OH 43210 1252, USA
    Am Heart J 156:641-648.e1. 2008
    ..Baseline characteristics for patients randomized in this trial are also presented...