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Genomes and Genes | Karl H SchuleriSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
The adult Göttingen minipig as a model for chronic heart failure after myocardial infarction: focus on cardiovascular imaging and regenerative therapiesKarl H Schuleri
Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
Comp Med 58:568-79. 2008..New heart failure therapies and devices can be tested preclinically in this adult animal model of chronic heart failure...- CT for evaluation of myocardial cell therapy in heart failure: a comparison with CMR imagingKarl H Schuleri
Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA
JACC Cardiovasc Imaging 4:1284-93. 2011..The aim of this study was to use multidetector computed tomography (MDCT) to assess therapeutic effects of myocardial regenerative cell therapies... - Reduced neuronal nitric oxide synthase expression contributes to cardiac oxidative stress and nitroso-redox imbalance in ob/ob miceRoberto M Saraiva
Cardiology Division, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
Nitric Oxide 16:331-8. 2007..These data offer novel insights into potential mechanisms of myocardial dysfunction in obesity... 
Multimodality noninvasive imaging demonstrates in vivo cardiac regeneration after mesenchymal stem cell therapyLuciano C Amado
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Am Coll Cardiol 48:2116-24. 2006....
Prospective electrocardiogram-gated delayed enhanced multidetector computed tomography accurately quantifies infarct size and reduces radiation exposureHyuk Jae Chang
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
JACC Cardiovasc Imaging 2:412-20. 2009....- Early improvement in cardiac tissue perfusion due to mesenchymal stem cellsKarl H Schuleri
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Physiol Heart Circ Physiol 294:H2002-11. 2008..Cardiac MRI-based measures of blood flow may be a useful tool to predict a successful myocardial regenerative process after MSC treatment... - Upregulation of arginase-II contributes to decreased age-related myocardial contractile reserveMehnaz Khan
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University Medicine, Tower 711, 600 N Wolfe St, Baltimore, MD 21287, USA
Eur J Appl Physiol 112:2933-41. 2012..4,014 ± 314 RFU/min/mg protein, p = 0.005). Arg-II upregulation in aging rat hearts contributes to age-related decreased contractile function... - [Stem cell therapy for myocardial regeneration: mechanisms and current clinical applications]Marco Centola
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
G Ital Cardiol (Rome) 9:234-50. 2008.... - Characterization of peri-infarct zone heterogeneity by contrast-enhanced multidetector computed tomography: a comparison with magnetic resonance imagingKarl H Schuleri
Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, Maryland 21205, USA
J Am Coll Cardiol 53:1699-707. 2009..This study examined whether multidetector computed tomography (MDCT) improves the ability to define peri-infarct zone (PIZ) heterogeneity relative to magnetic resonance imaging (MRI)... - Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scarAlbert C Lardo
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Circulation 113:394-404. 2006.... - Aging impairs the beneficial effect of granulocyte colony-stimulating factor and stem cell factor on post-myocardial infarction remodelingStephanie Lehrke
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Circ Res 99:553-60. 2006.... - Cardiovascular magnetic resonance characterization of peri-infarct zone remodeling following myocardial infarctionKarl H Schuleri
Johns Hopkins School of Medicine, Division of Cardiology, 1042 Ross Building, Baltimore, MD 21205, USA
J Cardiovasc Magn Reson 14:24. 2012..However, CMR data assessing the temporal formation and functional remodeling characteristics of this complex region are limited. We intended to characterize early temporal changes in scar morphology and regional function in the PIZ... - Xanthine oxidoreductase inhibition causes reverse remodeling in rats with dilated cardiomyopathyKhalid M Minhas
Cardiology Division, Department of Medicine, Institute for Cell Engineering, Johns Hopkins Medical Institutions, Baltimore, MD 21212, USA
Circ Res 98:271-9. 2006.... - Autologous mesenchymal stem cells produce reverse remodelling in chronic ischaemic cardiomyopathyKarl H Schuleri
Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
Eur Heart J 30:2722-32. 2009..Here we tested the hypothesis that autologous MSCs can be safely injected into a chronic myocardial infarct scar, reduce its size, and improve ventricular function... - Quantitative automated assessment of myocardial perfusion at cardiac catheterizationAndrew J Boyle
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Cardiol 102:980-7. 2008..Further studies to assess the prognostic value of this technique are warranted... - Integration of infarct size, tissue perfusion, and metabolism by hybrid cardiac positron emission tomography/computed tomography: evaluation in a porcine model of myocardial infarctionRiikka Lautamaki
Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD 21210, USA
Circ Cardiovasc Imaging 2:299-305. 2009..We used this technique to obtain biomorphological insights into the interrelation between tissue damage, inflammation, and microvascular obstruction early after myocardial infarction... - Applications of cardiac multidetector CT beyond coronary angiographyKarl H Schuleri
Department of Medicine, Division of Cardiology, Johns Hopkins University Baltimore, MD 21205, USA
Nat Rev Cardiol 6:699-710. 2009..In this Review, we discuss recent technical developments in cardiac MDCT and outline newly enabled noncoronary cardiac applications including viability assessment, myocardial perfusion and molecular imaging... - A new method for cardiac computed tomography regional function assessment: stretch quantifier for endocardial engraved zones (SQUEEZ)Amir Pourmorteza
Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Circ Cardiovasc Imaging 5:243-50. 2012..We developed a method to detect and track such features on the endocardium to extract a metric that reflects local myocardial contraction... - Recent developments in wide-detector cardiac computed tomographySang Il Choi
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, 720 Rutland Ave 1042 Ross Building, Baltimore, MD 21205, USA
Int J Cardiovasc Imaging 25:23-9. 2009..We will also review examples of wide detector coronary angiography imaging and discuss emerging complementary non-coronary applications that have been enabled by wide-detector MDCT imaging... - CT-based myocardial perfusion imaging-practical considerations: acquisition, image analysis, interpretation, and challengesVishal C Mehra
Department of Medicine, Division of Cardiology, Johns Hopkins University, 600 N Wolfe Street, Carnegie Building 565C, Baltimore, MD 21287, USA
J Cardiovasc Transl Res 4:437-48. 2011.... - Activation of the cardiac ciliary neurotrophic factor receptor reverses left ventricular hypertrophy in leptin-deficient and leptin-resistant obesityShubha V Y Raju
Division of Cardiology and Institute for Cell Engineering, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
Proc Natl Acad Sci U S A 103:4222-7. 2006.... - Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanismJochen Steppan
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Proc Natl Acad Sci U S A 103:4759-64. 2006..These findings have implications for therapy in pathophysiologic states such as aging and heart failure in which myocardial NO signaling is disrupted... - Molecular hybrid positron emission tomography/computed tomography imaging of cardiac angiotensin II type 1 receptorsKenji Fukushima
Division of Nuclear Medicine, Russell H Morgan Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA
J Am Coll Cardiol 60:2527-34. 2012..The goal of this study was to explore the feasibility of targeted imaging of the angiotensin II type 1 receptor (AT1R) in cardiac tissue, using clinical hybrid positron emission tomography/computed tomography (PET/CT)... - Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarctionLuciano C Amado
Department of Medicine, Cardiology Division, The Johns Hopkins Hospital, Blalock 618, 600 North Wolfe Street, Baltimore, MD 21287, USA
Proc Natl Acad Sci U S A 102:11474-9. 2005.... - Deficiency of neuronal nitric oxide synthase increases mortality and cardiac remodeling after myocardial infarction: role of nitroso-redox equilibriumRoberto M Saraiva
Cardiology Division, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
Circulation 112:3415-22. 2005..Counter to this idea, we tested the hypothesis that NOS1 has a protective effect after MI...