Research Topics
Species | Jack SamuelsSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Personality disorders: epidemiology and public health issuesJack Samuels
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Int Rev Psychiatry 23:223-33. 2011..Furthermore, primary and secondary prevention strategies are needed to reduce the individual and societal burdens from personality disorders in the community...
Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics StudyJack Samuels
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, School of Medicine, 600 N Wolfe St, Meyer 4 181, Baltimore, MD 21287 7228, USA
Am J Psychiatry 164:493-9. 2007..The objective of this study was to determine whether there are chromosomal regions specifically linked to compulsive hoarding behavior in families with obsessive-compulsive disorder...
Prevalence and correlates of hoarding behavior in a community-based sampleJack F Samuels
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 109, Baltimore, MD 21287 7228, USA
Behav Res Ther 46:836-44. 2008..These findings suggest that hoarding may be relatively prevalent and that alcohol dependence, personality disorder traits, and specific childhood adversities are associated with hoarding in the community...
Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics StudyJack F Samuels
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 4 181, Baltimore, MD 21287 7228, USA
Behav Res Ther 45:673-86. 2007..The findings suggest that hoarding behavior may help differentiate a distinct clinical subgroup of people with OCD and may aggregate in some OCD families. Indecision may be a risk factor for hoarding in these families...
Sex-specific clinical correlates of hoarding in obsessive-compulsive disorderJack F Samuels
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 4 181, Baltimore, MD 21287 7228, USA
Behav Res Ther 46:1040-6. 2008..These findings indicate that specific clinical correlates of hoarding in OCD are different in men and women and may reflect sex-specific differences in the course, expression, and/or etiology of hoarding behavior in OCD...
Recent advances in the genetics of obsessive-compulsive disorderJack F Samuels
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, 1629 Thames Street, Suite 401, Baltimore, MD 21231, USA
Curr Psychiatry Rep 11:277-82. 2009..Despite this complexity, further refinement of the phenotype and developments in molecular and statistical genetics hold promise for further deepening our genetic understanding of OCD in the future...
Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorderJack Samuels
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Med Genet B Neuropsychiatr Genet 156:472-7. 2011..00015) and in families with male affecteds (P = 0.0007). Although of nominal statistical significance considering the number of comparisons, these findings provide further support for the involvement of SLC1A1 in the pathogenesis of OCD...
Hoarding in obsessive compulsive disorder: results from a case-control studyJ Samuels
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore 21287, USA
Behav Res Ther 40:517-28. 2002..Hoarding appears to be transmitted in some OCD families and may differentiate a clinical subgroup of OCD...
Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorderVirginia L Willour
Department of Psychiatry and Behavioral Sciences, School of Medicine, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21287, USA
Am J Hum Genet 75:508-13. 2004..046 and .02, respectively) for association...
The association between parental bonding and obsessive compulsive disorder in offspring at high familial riskHolly C Wilcox
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287 7228, USA
J Affect Disord 111:31-9. 2008..The aim of the current study is to estimate the association between parenting factors derived from the Parental Bonding Instrument (PBI) and a lifetime DSM-IV diagnosis of OCD...
Factor analysis of the Yale-Brown Obsessive Compulsive Scale in a family study of obsessive-compulsive disorderBernadette Cullen
Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Depress Anxiety 24:130-8. 2007..There were specific clinical correlates for these factors, and significant intrafamilial sib-sib correlations were found for the Symmetry/Order and Hoarding factors...
Utility of the Leyton Obsessional Inventory to distinguish OCD and OCPDDavid Wellen
Department of Psychiatry and Behavioral Sciences, School of Medicine, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Depress Anxiety 24:301-6. 2007..These findings may contribute to effective diagnosis and treatment by allowing the LOI to screen for OCD and OCPD in a population exhibiting obsessional symptoms and traits...
The identification of OCD-related subgroups based on comorbidityGerald Nestadt
Department of Psychiatry and Behavioral Sciences, School of Medicine, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
Biol Psychiatry 53:914-20. 2003..This study employed latent class analysis (LCA) to explore whether there are underlying clinical constructs that distinguish "OCD-related" subgroups...
Social and communication difficulties and obsessive-compulsive disorderBernadette Cullen
Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Psychopathology 41:194-200. 2008..In this study we sought to establish if there is any association between the presence of abnormal pragmatic behaviors and OCD and whether this association delineates a familial subtype of OCD...
Evidence for potential relationship between SLC1A1 and a putative genetic linkage region on chromosome 14q to obsessive-compulsive disorder with compulsive hoardingKung Yee Liang
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Am J Med Genet B Neuropsychiatr Genet 147:1000-2. 2008....
Personality dimensions and criminal arrestJack Samuels
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Compr Psychiatry 45:275-80. 2004..The results suggest that specific dimensions of normal personality are related to criminal arrest in the community...
The relationship between the five-factor model and latent Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition personality disorder dimensionsGerald Nestadt
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Compr Psychiatry 49:98-105. 2008..Whether additional maladaptive traits would better define the domain of PDs remains an important objective for future research...
Agoraphobia in adults: incidence and longitudinal relationship with panicO Joseph Bienvenu
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 101, Baltimore, MD 21287, USA
Br J Psychiatry 188:432-8. 2006..Theories regarding how spontaneous panic and agoraphobia relate are based mostly on cross-sectional and/or clinic data...
Prevalence and correlates of personality disorders in a community sampleJack Samuels
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Br J Psychiatry 180:536-42. 2002..CONCLUSIONS: Approximately 9% of this community sample has a DSM-IV personality disorder. Personality disorders are over-represented in certain demographic subgroups of the community...
Latent structure of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition personality disorder criteriaGerald Nestadt
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Compr Psychiatry 47:54-62. 2006....
Identifying and reducing medication errors in psychiatry: creating a culture of safety through the use of an adverse event reporting mechanismGeetha Jayaram
Johns Hopkins Department of Psychiatry, Meyer 4 181, 600 N Wolfe St, Baltimore, MD 21287, USA
J Psychiatr Pract 17:81-8. 2011....
Monoamine oxidase A regulates antisocial personality in whites with no history of physical abuseIrving M Reti
The School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Compr Psychiatry 52:188-94. 2011..The 30-base pair variable number tandem repeat in the MAOA promoter regulates MAOA levels, but its effects on ASP in humans are unclear...
Familiality of factor analysis-derived YBOCS dimensions in OCD-affected sibling pairs from the OCD Collaborative Genetics StudyGregor Hasler
Laboratory of Clinical Science, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
Biol Psychiatry 61:617-25. 2007..While factor-analytic studies have found consistent, clinically meaningful OCD symptom dimensions, there have been only limited attempts to evaluate the familiality and potential genetic basis of such dimensions...
The longitudinal relationship between personality disorder dimensions and global functioning in a community-residing populationJin Pyo Hong
Department of Psychiatry, Asian Medical Center, School of Medicine, Ulsan University, Seoul, Korea
Psychol Med 35:891-5. 2005..This suggests that the functional effect of the other personality disorder traits may be mediated through their relationship with Axis I disorders. Future research is needed using more specific and sensitive outcome measures...
Clinical correlates of recurrent major depression in obsessive-compulsive disorderJin Pyo Hong
Department of Psychiatry, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea
Depress Anxiety 20:86-91. 2004..In a multiple logistic regression model, only early age of OCD diagnosis was significantly associated with RDD. Early age at onset of OCD increases the risk of depressive disorder in individuals with OCD...
Psychiatrists' ascertained treatment needs for mental disorders in a population-based sampleErick Messias
Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta 30912, USA
Psychiatr Serv 58:373-7. 2007..This study aimed to estimate need for treatment of alcohol dependence, major depression, panic disorder, agoraphobia, and social phobia...
