Sarven Sabunciyan

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Polymorphisms in the homeobox gene OTX2 may be a risk factor for bipolar disorder
    Sarven Sabunciyan
    Stanley Division of Developmental Neurovirology, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Am J Med Genet B Neuropsychiatr Genet 144:1083-6. 2007
  2. pmc DNA methylation signatures within the human brain
    Christine Ladd-Acosta
    Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Am J Hum Genet 81:1304-15. 2007
  3. pmc Putative psychosis genes in the prefrontal cortex: combined analysis of gene expression microarrays
    Kwang Ho Choi
    Stanley Laboratory of Brain Research, 9800 Medical Center Dr Bldg 2C, Rockville, MD 20850, USA
    BMC Psychiatry 8:87. 2008
  4. pmc Establishing the baseline level of repetitive element expression in the human cortex
    Svitlana Tyekucheva
    Department of Biostatistics and Computational Biology, Dana Farber CancerInstitute, 450 Brookline Ave, Boston, 02115, USA
    BMC Genomics 12:495. 2011
  5. pmc No difference in antibody titers against xenotropic MLV related virus in prostate cancer cases and cancer-free controls
    Sarven Sabunciyan
    Stanley Division of Developmental Virology, Department of Pediatrics, Johns Hopkins University, Baltimore, MD 21287, United States
    Mol Cell Probes 25:134-6. 2011
  6. pmc Genome-wide DNA methylation scan in major depressive disorder
    Sarven Sabunciyan
    Department of Pediatrics, Stanley Division of Developmental Neurovirology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 7:e34451. 2012
  7. pmc Increased methylation variation in epigenetic domains across cancer types
    Kasper Daniel Hansen
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Nat Genet 43:768-75. 2011
  8. doi Antibodies to retroviruses in recent onset psychosis and multi-episode schizophrenia
    Faith Dickerson
    The Stanley Research Program at Sheppard Pratt, Baltimore, MD, USA
    Schizophr Res 138:198-205. 2012
  9. pmc The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
    Rafael A Irizarry
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Nat Genet 41:178-86. 2009
  10. pmc Differential expression analysis of RNA-seq data at single-base resolution
    Alyssa C Frazee
    Department of Biostatistics, The Johns Hopkins University Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Biostatistics 15:413-26. 2014

Collaborators

Detail Information

Publications11

  1. ncbi Polymorphisms in the homeobox gene OTX2 may be a risk factor for bipolar disorder
    Sarven Sabunciyan
    Stanley Division of Developmental Neurovirology, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Am J Med Genet B Neuropsychiatr Genet 144:1083-6. 2007
    ..All individuals with the rs28757218 polymorphism were heterozygous for the allele. Based on this positive case-control association finding, we conclude that variations in OTX2 might confer risk for the development of bipolar disorder...
  2. pmc DNA methylation signatures within the human brain
    Christine Ladd-Acosta
    Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Am J Hum Genet 81:1304-15. 2007
    ..These results were validated for all six genes tested in a replicate set of 57 samples. Our data suggest that DNA methylation signatures distinguish brain regions and may help account for region-specific functional specialization...
  3. pmc Putative psychosis genes in the prefrontal cortex: combined analysis of gene expression microarrays
    Kwang Ho Choi
    Stanley Laboratory of Brain Research, 9800 Medical Center Dr Bldg 2C, Rockville, MD 20850, USA
    BMC Psychiatry 8:87. 2008
    ..Bipolar disorder with psychotic features may be closely related to schizophrenia and therefore, psychosis may be an alternative phenotype compared to the traditional diagnosis categories...
  4. pmc Establishing the baseline level of repetitive element expression in the human cortex
    Svitlana Tyekucheva
    Department of Biostatistics and Computational Biology, Dana Farber CancerInstitute, 450 Brookline Ave, Boston, 02115, USA
    BMC Genomics 12:495. 2011
    ..Hence, we performed whole transcriptome sequencing to investigate the expression of repetitive elements in human frontal cortex using postmortem tissue obtained from the Stanley Medical Research Institute...
  5. pmc No difference in antibody titers against xenotropic MLV related virus in prostate cancer cases and cancer-free controls
    Sarven Sabunciyan
    Stanley Division of Developmental Virology, Department of Pediatrics, Johns Hopkins University, Baltimore, MD 21287, United States
    Mol Cell Probes 25:134-6. 2011
    ..No statistically significant differences were observed in immunoreactivity between cases and controls for either the XMRV-env or the XMRV-gag antigen...
  6. pmc Genome-wide DNA methylation scan in major depressive disorder
    Sarven Sabunciyan
    Department of Pediatrics, Stanley Division of Developmental Neurovirology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 7:e34451. 2012
    ..Further studies using limbic system brain regions might shed additional light on this role...
  7. pmc Increased methylation variation in epigenetic domains across cancer types
    Kasper Daniel Hansen
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Nat Genet 43:768-75. 2011
    ..We suggest a model for cancer involving loss of epigenetic stability of well-defined genomic domains that underlies increased methylation variability in cancer that may contribute to tumor heterogeneity...
  8. doi Antibodies to retroviruses in recent onset psychosis and multi-episode schizophrenia
    Faith Dickerson
    The Stanley Research Program at Sheppard Pratt, Baltimore, MD, USA
    Schizophr Res 138:198-205. 2012
    ..Immunological abnormalities involving the upregulation of endogenous retroviruses have been associated with schizophrenia in small studies...
  9. pmc The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
    Rafael A Irizarry
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Nat Genet 41:178-86. 2009
    ....
  10. pmc Differential expression analysis of RNA-seq data at single-base resolution
    Alyssa C Frazee
    Department of Biostatistics, The Johns Hopkins University Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Biostatistics 15:413-26. 2014
    ..A software implementation of our method is available on github (https://github.com/alyssafrazee/derfinder). ..
  11. pmc Visualization and probability-based scoring of structural variants within repetitive sequences
    Eitan Halper-Stromberg
    Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Program in Human Genetics and Molecular Biology, Johns Hopkins University School of Medicine, Computational Bioscience Program, University of Colorado, Denver, Department of Molecular Biology and Genetics, Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Department of Pathology, Johns Hopkins University, High Throughput Biology Center, Johns Hopkins University School of Medicine, Johns Hopkins University, Center for Epigenetics, Johns Hopkins University School of Medicine, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD and Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Boston, Massachusetts, MA, USADepartment of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Program in Human Genetics and Molecular Biology, Johns Hopkins University School of Medicine, Computational Bioscience Program, University of Colorado, Denver, Department of Molecular Biology and Genetics, Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Department of Pathology, Johns Hopkins University, High Throughput Biology Center, Johns Hopkins University School of Medicine, Johns Hopkins University, Center for Epigenetics, Johns Hopkins University School of Medicine, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD and Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Boston
    Bioinformatics 30:1514-21. 2014
    ..Complicating the matter are repetitive regions subject to programmed rearrangements, as is the case with the antigen-binding domains in the Immunoglobulin (Ig) and T-cell receptor (TCR) loci...