M R Rountree

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
    M R Rountree
    The Johns Hopkins Oncology Center, Tumor Biology Laboratory, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Nat Genet 25:269-77. 2000
  2. ncbi Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
    S B Baylin
    The Johns Hopkins Comprehensive Cancer Center and Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Hum Mol Genet 10:687-92. 2001
  3. ncbi Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin
    K E Bachman
    The Johns Hopkins Oncology Center, Tumor Biology Laboratory, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    J Biol Chem 276:32282-7. 2001
  4. ncbi DNA methylation, chromatin inheritance, and cancer
    M R Rountree
    The Johns Hopkins Oncology Center, Tumor Biology Laboratory, The Johns Hopkins University School of Medicine, Baltimore, Maryland, MD 21231, USA
    Oncogene 20:3156-65. 2001

Collaborators

Detail Information

Publications4

  1. ncbi DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
    M R Rountree
    The Johns Hopkins Oncology Center, Tumor Biology Laboratory, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Nat Genet 25:269-77. 2000
    ..Thus, DNMT1 not only maintains DNA methylation, but also may directly target, in a heritable manner, transcriptionally repressive chromatin to the genome during DNA replication...
  2. ncbi Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
    S B Baylin
    The Johns Hopkins Comprehensive Cancer Center and Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Hum Mol Genet 10:687-92. 2001
    ..In the translational arena, the promoter hypermethylation changes hold great promise as DNA tumor markers and their potentially reversible state creates a target for cancer therapeutic strategies involving gene reactivation...
  3. ncbi Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin
    K E Bachman
    The Johns Hopkins Oncology Center, Tumor Biology Laboratory, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    J Biol Chem 276:32282-7. 2001
    ....
  4. ncbi DNA methylation, chromatin inheritance, and cancer
    M R Rountree
    The Johns Hopkins Oncology Center, Tumor Biology Laboratory, The Johns Hopkins University School of Medicine, Baltimore, Maryland, MD 21231, USA
    Oncogene 20:3156-65. 2001
    ....