Fausto J Rodriguez

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Genetic predisposition to peripheral nerve neoplasia: diagnostic criteria and pathogenesis of neurofibromatoses, Carney complex, and related syndromes
    Fausto J Rodriguez
    Division of Neuropathology, Department of Pathology, Johns Hopkins University, 720 Rutland Avenue, Ross Building, 512B, Baltimore, MD 21205, USA
    Acta Neuropathol 123:349-67. 2012
  2. pmc BRAF duplications and MAPK pathway activation are frequent in gliomas of the optic nerve proper
    Fausto J Rodriguez
    Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland 21205, USA
    J Neuropathol Exp Neurol 71:789-94. 2012
  3. doi request reprint Disseminated oligodendroglial-like leptomeningeal tumor of childhood: a distinctive clinicopathologic entity
    Fausto J Rodriguez
    Department of Pathology, Division of Neuropathology, Johns Hopkins Hospital, Johns Hopkins University, Baltimore, MD, 21231, USA
    Acta Neuropathol 124:627-41. 2012
  4. pmc Neoplastic cells are a rare component in human glioblastoma microvasculature
    Fausto J Rodriguez
    Department of Pathology, Division of Neuropathology, Johns Hopkins University, MD, USA
    Oncotarget 3:98-106. 2012
  5. pmc Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems
    Fausto J Rodriguez
    Division of Neuropathology, Department of Pathology, Johns Hopkins University, 720 Rutland Avenue, Ross Building, 512B, Baltimore, MD 21205, USA
    Acta Neuropathol 123:295-319. 2012
  6. doi request reprint Superficial neurofibromas in the setting of schwannomatosis: nosologic implications
    Fausto J Rodriguez
    Division of Neuropathology, Department of Pathology, Johns Hopkins University, Baltimore, MD 21205, USA
    Acta Neuropathol 121:663-8. 2011
  7. pmc Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
    Yuchen Jiao
    Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, The Johns Hopkins Kimmel Cancer Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Oncotarget 3:709-22. 2012
  8. pmc Mutations in CIC and FUBP1 contribute to human oligodendroglioma
    Chetan Bettegowda
    Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA
    Science 333:1453-5. 2011
  9. pmc MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2
    Cheng Ying Ho
    Division of Neuropathology, Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21231, USA
    Neuro Oncol 15:69-82. 2013
  10. pmc Exomic sequencing of four rare central nervous system tumor types
    Chetan Bettegowda
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Oncotarget 4:572-83. 2013

Collaborators

Detail Information

Publications19

  1. pmc Genetic predisposition to peripheral nerve neoplasia: diagnostic criteria and pathogenesis of neurofibromatoses, Carney complex, and related syndromes
    Fausto J Rodriguez
    Division of Neuropathology, Department of Pathology, Johns Hopkins University, 720 Rutland Avenue, Ross Building, 512B, Baltimore, MD 21205, USA
    Acta Neuropathol 123:349-67. 2012
    ..In this review, we provide a concise update on the diagnostic criteria, pathology and molecular pathogenesis of these enigmatic syndromes in relation to peripheral nerve sheath neoplasia...
  2. pmc BRAF duplications and MAPK pathway activation are frequent in gliomas of the optic nerve proper
    Fausto J Rodriguez
    Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland 21205, USA
    J Neuropathol Exp Neurol 71:789-94. 2012
    ....
  3. doi request reprint Disseminated oligodendroglial-like leptomeningeal tumor of childhood: a distinctive clinicopathologic entity
    Fausto J Rodriguez
    Department of Pathology, Division of Neuropathology, Johns Hopkins Hospital, Johns Hopkins University, Baltimore, MD, 21231, USA
    Acta Neuropathol 124:627-41. 2012
    ..We report a series of a neoplasm with distinct clinicopathologic and molecular features. Although most progress slowly, a significant fraction develop aggressive features...
  4. pmc Neoplastic cells are a rare component in human glioblastoma microvasculature
    Fausto J Rodriguez
    Department of Pathology, Division of Neuropathology, Johns Hopkins University, MD, USA
    Oncotarget 3:98-106. 2012
    ....
  5. pmc Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems
    Fausto J Rodriguez
    Division of Neuropathology, Department of Pathology, Johns Hopkins University, 720 Rutland Avenue, Ross Building, 512B, Baltimore, MD 21205, USA
    Acta Neuropathol 123:295-319. 2012
    ..In the current review, we attempt to provide some useful guidelines for the surgical neuropathologist to help navigate these persistent, challenging problems...
  6. doi request reprint Superficial neurofibromas in the setting of schwannomatosis: nosologic implications
    Fausto J Rodriguez
    Division of Neuropathology, Department of Pathology, Johns Hopkins University, Baltimore, MD 21205, USA
    Acta Neuropathol 121:663-8. 2011
    ..In particular, the presence of a cutaneous neurofibroma in a patient with multiple schwannomas should not lead to a diagnosis of NF2...
  7. pmc Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
    Yuchen Jiao
    Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, The Johns Hopkins Kimmel Cancer Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Oncotarget 3:709-22. 2012
    ....
  8. pmc Mutations in CIC and FUBP1 contribute to human oligodendroglioma
    Chetan Bettegowda
    Ludwig Center for Cancer Genetics and Howard Hughes Medical Institutions, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21287, USA
    Science 333:1453-5. 2011
    ..These results suggest a critical role for these genes in the biology and pathology of oligodendrocytes...
  9. pmc MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2
    Cheng Ying Ho
    Division of Neuropathology, Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21231, USA
    Neuro Oncol 15:69-82. 2013
    ..A unique miRNA profile exists in PA, compared with brain tissue. These miRNAs and their targets may play a role in the pathogenesis of PA...
  10. pmc Exomic sequencing of four rare central nervous system tumor types
    Chetan Bettegowda
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Oncotarget 4:572-83. 2013
    ..Our study supports the hypothesis that pathologically similar tumors arising in different age groups and from different compartments may represent distinct disease processes with varied genetic composition...
  11. doi request reprint BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants
    Alex Lin
    Division of Neuropathology, Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA
    J Neuropathol Exp Neurol 71:66-72. 2012
    ..The prognostic and therapeutic significance of this alteration is unclear and merits further study...
  12. pmc Phenotypic variations in NF1-associated low grade astrocytomas: possible role for increased mTOR activation in a subset
    Mark Jentoft
    Departments of Laboratory Medicine and Pathology, Johns Hopkins University, Baltimore, MD, USA
    Int J Clin Exp Pathol 4:43-57. 2010
    ..In summary, differential expression of neuronal-related genes and increased mTOR activation may underlie phenotypic variations in NF1-associated low grade astrocytomas...
  13. doi request reprint Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas
    Doreen N Nguyen
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Brain Pathol 23:237-43. 2013
    ..Future studies are required to clarify the clinical and biological significance of ALT in high-grade astrocytomas...
  14. pmc Pathological and molecular advances in pediatric low-grade astrocytoma
    Fausto J Rodriguez
    Department of Pathology, Johns Hopkins UniversitySchool of Medicine, Baltimore, Maryland 21205, USA
    Annu Rev Pathol 8:361-79. 2013
    ..In this review, we attempt to summarize this rapidly developing field and discuss the potential for translating our growing molecular knowledge into improved diagnostic and prognostic biomarkers and new targeted therapies...
  15. ncbi request reprint Ependymomas with neuronal differentiation: a morphologic and immunohistochemical spectrum
    Fausto J Rodriguez
    Department of Pathology, Mayo Clinic, Rochester, MN, USA
    Acta Neuropathol 113:313-24. 2007
    ..The clinical significance of these observations is unknown but deserves further exploration...
  16. pmc Altered telomeres in tumors with ATRX and DAXX mutations
    Christopher M Heaphy
    Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
    Science 333:425. 2011
    ..ATRX mutations also correlate with abnormal telomeres in tumors of the central nervous system. These data suggest that an alternative telomere maintenance function may operate in human tumors with alterations in the ATRX or DAXX genes...
  17. pmc Identification of t(1;19)(q12;p13) and ploidy changes in an ependymosarcoma: a cytogenetic evaluation
    Abeer Z Tabbarah
    Department of Pathology, George Washington University, Washington, D C, USA
    Clin Neuropathol 31:142-5. 2012
    ..The significance of the genetic alterations we describe associated with sarcomatoid change in ependymal neoplasms, and ultimately their prognostic relevance, merits further study...
  18. doi request reprint Limited detection of IgH gene rearrangements in plasma of patients with primary central nervous system lymphoma
    Jian He
    Ludwig Center for Cancer Genetics and Therapeutics, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA
    J Neurooncol 114:275-9. 2013
    ..Alternative strategies to develop circulating biomarkers for PCNSL patients need to be explored. ..
  19. doi request reprint BRAF alterations are frequent in cerebellar low-grade astrocytomas with diffuse growth pattern
    Cristiane M Ida
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Neuropathol Exp Neurol 71:631-9. 2012
    ....