Corban G Rivera

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Sensitive detection of pathway perturbations in cancers
    Corban G Rivera
    Department of Computer Science, Virginia Tech, Blacksburg, VA, USA
    BMC Bioinformatics 13:S9. 2012
  2. pmc Novel peptide-specific quantitative structure-activity relationship (QSAR) analysis applied to collagen IV peptides with antiangiogenic activity
    Corban G Rivera
    Department of Biomedical Engineering, 613 Traylor Building, Johns Hopkins University, 720 Rutland Avenue, Baltimore, Maryland 21205, United States
    J Med Chem 54:6492-500. 2011
  3. pmc NeMo: Network Module identification in Cytoscape
    Corban G Rivera
    Department of Biomedical Engineering and High Throughput Biology Center, Johns Hopkins School of Medicine, Baltimore, MD 21218, USA
    BMC Bioinformatics 11:S61. 2010
  4. pmc Analysis of VEGF--a regulated gene expression in endothelial cells to identify genes linked to angiogenesis
    Corban G Rivera
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 6:e24887. 2011
  5. pmc Angiogenesis-associated crosstalk between collagens, CXC chemokines, and thrombospondin domain-containing proteins
    Corban G Rivera
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Ann Biomed Eng 39:2213-22. 2011
  6. pmc Synergy between a collagen IV mimetic peptide and a somatotropin-domain derived peptide as angiogenesis and lymphangiogenesis inhibitors
    Jacob E Koskimaki
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Angiogenesis 16:159-70. 2013
  7. pmc Anti-angiogenic peptides for cancer therapeutics
    Elena V Rosca
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Curr Pharm Biotechnol 12:1101-16. 2011
  8. pmc Constructing the angiome: a global angiogenesis protein interaction network
    Liang Hui Chu
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Physiol Genomics 44:915-24. 2012
  9. doi request reprint Network legos: building blocks of cellular wiring diagrams
    T M Murali
    Department of Computer Science, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
    J Comput Biol 15:829-44. 2008
  10. pmc Serpin-derived peptides are antiangiogenic and suppress breast tumor xenograft growth
    Jacob E Koskimaki
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Transl Oncol 5:92-7. 2012

Detail Information

Publications12

  1. pmc Sensitive detection of pathway perturbations in cancers
    Corban G Rivera
    Department of Computer Science, Virginia Tech, Blacksburg, VA, USA
    BMC Bioinformatics 13:S9. 2012
    ..Associations detected between diseases and perturbations in well-defined pathways within such interaction networks have the potential to illuminate the molecular mechanisms underlying disease progression and response to treatment...
  2. pmc Novel peptide-specific quantitative structure-activity relationship (QSAR) analysis applied to collagen IV peptides with antiangiogenic activity
    Corban G Rivera
    Department of Biomedical Engineering, 613 Traylor Building, Johns Hopkins University, 720 Rutland Avenue, Baltimore, Maryland 21205, United States
    J Med Chem 54:6492-500. 2011
    ..We found that the models produced quantitatively accurate predictions of activity and provided insight into collagen IV derived peptide structure-activity relationships...
  3. pmc NeMo: Network Module identification in Cytoscape
    Corban G Rivera
    Department of Biomedical Engineering and High Throughput Biology Center, Johns Hopkins School of Medicine, Baltimore, MD 21218, USA
    BMC Bioinformatics 11:S61. 2010
    ..In this work, we present a novel method to identify densely connected and bipartite network modules based on a log odds score for shared neighbours...
  4. pmc Analysis of VEGF--a regulated gene expression in endothelial cells to identify genes linked to angiogenesis
    Corban G Rivera
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 6:e24887. 2011
    ..The analysis showed differential regulation of HIF-1α and HIF-2α. The data also provided additional evidence for the role of endothelial cells in Alzheimer's disease...
  5. pmc Angiogenesis-associated crosstalk between collagens, CXC chemokines, and thrombospondin domain-containing proteins
    Corban G Rivera
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Ann Biomed Eng 39:2213-22. 2011
    ..We identified six proteins at the center of the angiogenesis-associated network including three syndecans, MMP9, CD44, and versican. These findings shed light on the complex signaling networks that govern angiogenesis phenomena...
  6. pmc Synergy between a collagen IV mimetic peptide and a somatotropin-domain derived peptide as angiogenesis and lymphangiogenesis inhibitors
    Jacob E Koskimaki
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Angiogenesis 16:159-70. 2013
    ....
  7. pmc Anti-angiogenic peptides for cancer therapeutics
    Elena V Rosca
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Curr Pharm Biotechnol 12:1101-16. 2011
    ..g., through L-to-D and non-natural amino acid substitutions. We highlight technological advances in peptide discovery and optimization including computational and bioinformatics tools and novel experimental techniques...
  8. pmc Constructing the angiome: a global angiogenesis protein interaction network
    Liang Hui Chu
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Physiol Genomics 44:915-24. 2012
    ..The results of this analysis can be used to identify genes and proteins in different disease conditions and putative targets for therapeutic interventions as high-ranked candidates for experimental validation...
  9. doi request reprint Network legos: building blocks of cellular wiring diagrams
    T M Murali
    Department of Computer Science, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
    J Comput Biol 15:829-44. 2008
    ..Source code implementing our algorithms is available under version 2 of the GNU General Public License at http://bioinformatics.cs.vt.edu/ murali/software/network-lego...
  10. pmc Serpin-derived peptides are antiangiogenic and suppress breast tumor xenograft growth
    Jacob E Koskimaki
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Transl Oncol 5:92-7. 2012
    ..We tested the peptide derived from DEAH box helicase protein in a triple-negative MDA-MB-231 breast orthotopic xenograft model in severe combined immunodeficient mice and show significant tumor suppression...
  11. pmc VIRGO: computational prediction of gene functions
    Naveed Massjouni
    660 McBryde Hall, Department of Computer Science, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA
    Nucleic Acids Res 34:W340-4. 2006
    ..For each prediction, VIRGO also provides an informative 'propagation diagram' that traces the flow of information in the FLN that led to the prediction. VIRGO is available at http://whipple.cs.vt.edu:8080/virgo...
  12. pmc The human-bacterial pathogen protein interaction networks of Bacillus anthracis, Francisella tularensis, and Yersinia pestis
    Matthew D Dyer
    Virginia Bioinformatics Institute, Blacksburg, Virginia, United States of America
    PLoS ONE 5:e12089. 2010
    ..However, the interactions between human proteins and proteins in these bacteria remain poorly characterized leading to an incomplete understanding of their pathogenesis and mechanisms of immune evasion...