Andrew D Redd

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Liver stiffness is associated with monocyte activation in HIV-infected Ugandans without viral hepatitis
    Andrew D Redd
    Laboratory of Immunoregulation, NIAID, NIH, Baltimore, MD 21205, USA
    AIDS Res Hum Retroviruses 29:1026-30. 2013
  2. pmc The rates of HIV superinfection and primary HIV incidence in a general population in Rakai, Uganda
    Andrew D Redd
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, MD 21205, USA
    J Infect Dis 206:267-74. 2012
  3. pmc T-cell enumeration from dried blood spots by quantifying rearranged T-cell receptor-beta genes
    Andrew D Redd
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    J Immunol Methods 354:40-4. 2010
  4. pmc Efficiency of CCR5 coreceptor utilization by the HIV quasispecies increases over time, but is not associated with disease progression
    Andrew D Redd
    Laboratory of Immunoregulation, NIAID, NIH, Bethesda, Maryland, USA
    AIDS Res Hum Retroviruses 28:289-94. 2012
  5. pmc Male circumcision and herpes simplex virus type 2 infection in female partners: a randomized trial in Rakai, Uganda
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    J Infect Dis 205:486-90. 2012
  6. pmc Previously transmitted HIV-1 strains are preferentially selected during subsequent sexual transmissions
    Andrew D Redd
    Laboratory of Immunoregulation, Division of Intramural Research DIR, National Institute of Allergy and Infectious Diseases NIAID, National Institutes of Health NIH, Bethesda, MD, USA
    J Infect Dis 206:1433-42. 2012
  7. pmc Geographic HIV type 1 subtype distribution in Rakai district, Uganda
    Aleisha N Collinson-Streng
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, MD 21205, USA
    AIDS Res Hum Retroviruses 25:1045-8. 2009
  8. pmc Human papillomavirus clearance among males is associated with HIV acquisition and increased dendritic cell density in the foreskin
    Aaron A R Tobian
    Department of Pathology, Johns Hopkins University, Carnegie 437, 600 N Wolfe St, Baltimore, MD 21287, USA
    J Infect Dis 207:1713-22. 2013
  9. pmc Identification of new CRF51_01B in Singapore using full genome analysis of three HIV type 1 isolates
    Oon Tek Ng
    Johns Hopkins School of Medicine, Johns Hopkins Medical Institution, Baltimore, MD, USA
    AIDS Res Hum Retroviruses 28:527-30. 2012
  10. pmc Identification of HIV superinfection in seroconcordant couples in Rakai, Uganda, by use of next-generation deep sequencing
    Andrew D Redd
    Johns Hopkins University School of Medicine, Rangos Building, Room 530, 855 N Wolfe St, Baltimore, MD 21205, USA
    J Clin Microbiol 49:2859-67. 2011

Collaborators

Detail Information

Publications24

  1. pmc Liver stiffness is associated with monocyte activation in HIV-infected Ugandans without viral hepatitis
    Andrew D Redd
    Laboratory of Immunoregulation, NIAID, NIH, Baltimore, MD 21205, USA
    AIDS Res Hum Retroviruses 29:1026-30. 2013
    ..Liver stiffness in HIV-infected Ugandans is associated with increased sCD14 indicative of monocyte activation in the absence of viral hepatitis or microbial translocation, and suggests that HIV may be directly involved in liver disease...
  2. pmc The rates of HIV superinfection and primary HIV incidence in a general population in Rakai, Uganda
    Andrew D Redd
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, MD 21205, USA
    J Infect Dis 206:267-74. 2012
    ..Human immunodeficiency virus (HIV) superinfection has been documented in high-risk individuals; however, the rate of superinfection among HIV-infected individuals within a general population remains unknown...
  3. pmc T-cell enumeration from dried blood spots by quantifying rearranged T-cell receptor-beta genes
    Andrew D Redd
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    J Immunol Methods 354:40-4. 2010
    ..This technique as well as other dried blood spot based technologies could increase the diagnostic and monitoring capabilities in resource-limited settings...
  4. pmc Efficiency of CCR5 coreceptor utilization by the HIV quasispecies increases over time, but is not associated with disease progression
    Andrew D Redd
    Laboratory of Immunoregulation, NIAID, NIH, Bethesda, Maryland, USA
    AIDS Res Hum Retroviruses 28:289-94. 2012
    ..These data demonstrate that the R5-UE of the viral quasispecies early in HIV infection is not associated with disease progression, and that R5-UE levels increase in HIV-infected individuals over time...
  5. pmc Male circumcision and herpes simplex virus type 2 infection in female partners: a randomized trial in Rakai, Uganda
    Aaron A R Tobian
    Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    J Infect Dis 205:486-90. 2012
    ..17 cases per 100 person-years in the control arm (IRR, 0.85 [95% CI, .44-1.67]; P = .62). Contrary to findings in males, male circumcision did not affect HSV-2 acquisition among female partners...
  6. pmc Previously transmitted HIV-1 strains are preferentially selected during subsequent sexual transmissions
    Andrew D Redd
    Laboratory of Immunoregulation, Division of Intramural Research DIR, National Institute of Allergy and Infectious Diseases NIAID, National Institutes of Health NIH, Bethesda, MD, USA
    J Infect Dis 206:1433-42. 2012
    ..A genetic bottleneck is known to exist for human immunodeficiency virus (HIV) at the point of sexual transmission. However, the nature of this bottleneck and its effect on viral diversity over time is unclear...
  7. pmc Geographic HIV type 1 subtype distribution in Rakai district, Uganda
    Aleisha N Collinson-Streng
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, MD 21205, USA
    AIDS Res Hum Retroviruses 25:1045-8. 2009
    ..001) and more subtype D in southern clusters compared with northern clusters (78% vs. 65%, p < 0.008). These data illustrate the geographic complexity of subtype variation, which has important implications for HIV-1 vaccine design...
  8. pmc Human papillomavirus clearance among males is associated with HIV acquisition and increased dendritic cell density in the foreskin
    Aaron A R Tobian
    Department of Pathology, Johns Hopkins University, Carnegie 437, 600 N Wolfe St, Baltimore, MD 21287, USA
    J Infect Dis 207:1713-22. 2013
    ..The association between human papillomavirus (HPV) infection and the risk of human immunodeficiency virus (HIV) seroconversion is unclear, and the genital cellular immunology has not been evaluated...
  9. pmc Identification of new CRF51_01B in Singapore using full genome analysis of three HIV type 1 isolates
    Oon Tek Ng
    Johns Hopkins School of Medicine, Johns Hopkins Medical Institution, Baltimore, MD, USA
    AIDS Res Hum Retroviruses 28:527-30. 2012
    ..As the three patients were not epidemiologically linked, this recombinant form has been designated CRF51_01B. Identification of the novel recombinant forms indicates ongoing active HIV-1 transmission in Singapore...
  10. pmc Identification of HIV superinfection in seroconcordant couples in Rakai, Uganda, by use of next-generation deep sequencing
    Andrew D Redd
    Johns Hopkins University School of Medicine, Rangos Building, Room 530, 855 N Wolfe St, Baltimore, MD 21205, USA
    J Clin Microbiol 49:2859-67. 2011
    ..Our results indicate that NGS can be used for detection of HIV superinfection within large cohorts, which could assist in determining the incidence and the epidemiologic, virologic, and immunological correlates of this phenomenon...
  11. pmc C-reactive protein levels increase during HIV-1 disease progression in Rakai, Uganda, despite the absence of microbial translocation
    Andrew D Redd
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    J Acquir Immune Defic Syndr 54:556-9. 2010
    ..However, the role of general immune activation in HIV disease progression in this population was not fully examined...
  12. pmc Changes in the distribution of HIV type 1 subtypes D and A in Rakai District, Uganda between 1994 and 2002
    Samantha A Conroy
    Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, Maryland, USA
    AIDS Res Hum Retroviruses 26:1087-91. 2010
    ..Over this 8-year period, the overall viral population in this region evolved toward the less virulent HIV-1A strain, most likely as a consequence of the faster disease progression and lower transmissibility of HIV-1D...
  13. pmc Frequency of long-term nonprogressors in HIV-1 seroconverters From Rakai Uganda
    Oliver Laeyendecker
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    J Acquir Immune Defic Syndr 52:316-9. 2009
    ..Studies on long-term nonprogressors (LTNP) have been conducted in the USA and Europe. This study examined the frequency of LTNPs and HIV controllers among 637 HIV-1 seroconverters in rural Uganda...
  14. pmc Frequency and implications of HIV superinfection
    Andrew D Redd
    Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Lancet Infect Dis 13:622-8. 2013
    ..Additional collaborative research could benefit care of patients and inform future vaccine design. ..
  15. pmc Comparison of a high-resolution melting assay to next-generation sequencing for analysis of HIV diversity
    Matthew M Cousins
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Clin Microbiol 50:3054-9. 2012
    ..The HRM diversity assay is faster and less expensive than NGS, facilitating rapid analysis of large studies of HIV diversity and evolution...
  16. pmc Effects of HIV-1 and herpes simplex virus type 2 infection on lymphocyte and dendritic cell density in adult foreskins from Rakai, Uganda
    Kristine E Johnson
    Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Infect Dis 203:602-9. 2011
    ..To assess the cellular basis for these associations, we estimated immunologic cellular densities in foreskin tissue...
  17. pmc Molecular epidemiology of HIV type 1 in Singapore and identification of novel CRF01_AE/B recombinant forms
    Oon Tek Ng
    Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    AIDS Res Hum Retroviruses 27:1135-7. 2011
    ..However, 85% of subjects infected with the novel recombinant forms self-identified as men who have sex with men or bisexuals compared with only 41% of individuals infected with CRF01_AE and 62% infected with subtype B (p = 0.001)...
  18. doi request reprint Limited HIV-1 Superinfection in Seroconverters from the CAPRISA 004 Microbicide Trial
    Andrew D Redd
    Laboratory of Immunoregulation, Division of Intramural Research, NIAID, NIH, Bethesda, Maryland, USA
    J Clin Microbiol 52:844-8. 2014
    ..A better understanding of the rate of HIV superinfection could have important implications for ongoing HIV vaccine research. ..
  19. ncbi request reprint CD4 immunodiagnostics for HIV in the developing world
    Andrew D Redd
    Division of Intramural Research, National Institutes of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nat Rev Microbiol 6:S1. 2008
    ..Here, Andrew Redd and Thomas Quinn introduce the supplement...
  20. pmc Analysis of genetic linkage of HIV from couples enrolled in the HIV Prevention Trials Network 052 trial
    Susan H Eshleman
    Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21205, USA
    J Infect Dis 204:1918-26. 2011
    ..We analyzed HIV from 38 index-partner pairs and 80 unrelated index participants (controls) to assess the linkage of seroconversion events...
  21. pmc Short communication: Colony-forming hematopoietic progenitor cells are not preferentially infected by HIV type 1 subtypes A and D in vivo
    Caroline E Mullis
    Johns Hopkins Medical Institute, Johns Hopkins University, Baltimore, Maryland, USA
    AIDS Res Hum Retroviruses 28:1119-23. 2012
    ..Our findings suggest that HIV-1 subtypes A and D do not preferentially infect colony-forming HPCs over mature HIV target cells in vivo...
  22. doi request reprint Molecular tools for studying HIV transmission in sexual networks
    Mary K Grabowski
    aBloomberg School of Public Health, Johns Hopkins University bLaboratory of Immunoregulation, NIAID, NIH, Baltimore, Maryland, USA
    Curr Opin HIV AIDS 9:126-33. 2014
    ..The purpose of this review is to highlight the current utilities and limitations of phylogenetics in HIV epidemiological research from sample collection through to data analysis...
  23. pmc Microbial translocation, the innate cytokine response, and HIV-1 disease progression in Africa
    Andrew D Redd
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 106:6718-23. 2009
    ..These data suggest that microbial translocation and its subsequent inflammatory immune response do not have a causal relationship with HIV-1 disease progression in Africa...
  24. pmc Absence of detectable xenotropic murine leukemia virus-related virus in plasma or peripheral blood mononuclear cells of human immunodeficiency virus type 1-infected blood donors or individuals in Africa
    Shixing Tang
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    Transfusion 51:463-8. 2011
    ....