Research Topics
Species | L C RacusenSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
The Banff 97 working classification of renal allograft pathologyL C Racusen
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Kidney Int 55:713-23. 1999..This manuscript describes a classification, Banff 97, developed by investigators using the Banff Schema and the Collaborative Clinical Trials in Transplantation (CCTT) modification for diagnosis of renal allograft pathology...
Subclinical acute antibody-mediated rejection in positive crossmatch renal allograftsM Haas
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Am J Transplant 7:576-85. 2007..5 +/- 2.5 versus 1.0 +/- 2.0, p = 0.01) than that in 24 recipients of HLA-incompatible grafts with no AMR over a similar interval (360 +/- 117 days), suggesting that subclinical AMR may contribute to development of CAN...
CD20-positive infiltrates in renal allograft biopsies with acute cellular rejection are not associated with worse graft survivalS M Bagnasco
Department of Pathology, Johns Hopkins University, Baltimore, MD, USA
Am J Transplant 7:1968-73. 2007..Our data do not support association of B cell-rich infiltrates in allograft biopsies and worse outcome in acute rejection type I or II, but do not exclude the possible contribution of B cells to allograft rejection...
Effect of Bw4 and Bw6 epitope mismatches on antibody production, acute and chronic rejection, and graft survival in renal allograftsM S Leffell
Depaertment of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Transplantation 72:433-7. 2001..CONCLUSIONS: Mismatching for Bw4 or Bw6 does not confer any independent, increased risk for humoral sensitization or renal allograft failure...
Subclinical rejection in stable positive crossmatch kidney transplant patients: incidence and correlationsE S Kraus
Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Transplant 9:1826-34. 2009..Surveillance biopsies during the first year post-transplantation for these high-risk patients uncover clinically occult processes and phenotypes, which without intervention diminish allograft survival and function...
Cohort study of the prognostic significance of acute transplant glomerulitis in acutely rejecting renal allograftsN C Messias
Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
Transplantation 72:655-60. 2001..97; P=0.97). CONCLUSION: In this study, G was significantly more common in highly sensitized patients and was strongly associated with vascular rejection biopsies but was not an independent predictor of graft survival...
Guidelines for the diagnosis of antibody-mediated rejection in pancreas allografts-updated Banff grading schemaC B Drachenberg
Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA
Am J Transplant 11:1792-802. 2011..A systematized clinicopathological approach to AMR is essential for the development and assessment of much needed therapeutic interventions...
Ritonavir-induced acute kidney injury: kidney biopsy findings and review of literatureT Shafi
Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD 21224 2780, USA
Clin Nephrol 75:60-4. 2011..This is the first report of a kidney biopsy and pathology in acute kidney injury associated with ritonavir. A review of published medical literature on the topic is also presented...
Banff schema for grading pancreas allograft rejection: working proposal by a multi-disciplinary international consensus panelC B Drachenberg
Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA
Am J Transplant 8:1237-49. 2008....
C4d and C3d staining in biopsies of ABO- and HLA-incompatible renal allografts: correlation with histologic findingsM Haas
Department of Pathology, John Hopkins Medical Institutions, Baltimore, Maryland, USA
Am J Transplant 6:1829-40. 2006....
Antibody-mediated rejection in the kidneyL C Racusen
Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Transplant Proc 36:768-9. 2004..Antibody-mediated rejection is increasingly recognized as a cause of acute and chronic rejection in kidney as well as other organ allografts. New diagnostic criteria have been drafted to diagnose this entity and enable timely therapy...
Epithelial cell shedding in acute renal injuryL C Racusen
Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Clin Exp Pharmacol Physiol 25:273-5. 1998..Phalloidin stabilized the filaments and prevented the changes in cell shape indicative of altered adherence...
The Banff schema and differential diagnosis of allograft dysfunctionL C Racusen
Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Transplant Proc 36:753-4. 2004..This article reviews the criteria for diagnosis of rejection, and its differentiation from other inflammatory infiltrates in renal allograft biopsy specimens...
Structural correlates of renal electrolyte alterations in acute renal failureL C Racusen
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD
Miner Electrolyte Metab 17:72-88. 1991....
