Research Topics
Species | P V RabinsSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Predictors of progression to severe Alzheimer's disease in an incidence samplePeter V Rabins
Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA
Alzheimers Dement 9:204-7. 2013..Little is known about factors influencing time to severe Alzheimer's disease (AD)...
Do we know enough to begin prevention interventions for dementia?Peter V Rabins
Johns Hopkins School of Medicine, Baltimore, MD, USA
Alzheimers Dement 3:S86-8. 2007..The evidence that risk factors for vascular disease--hypertension, hyperlipidemia, and diabetes mellitus--increase the incidence of dementia supports a prevention campaign now...
Can suicide be a rational and ethical act in persons with early or pre-dementia?Peter V Rabins
Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Meyer 279, Baltimore, MD 21287, USA
Am J Bioeth 7:47-9. 2007
Long-term follow-up and phenomenologic differences distinguish among late-onset schizophrenia, late-life depression, and progressive dementiaPeter V Rabins
Departments of Psychiatry and Behavioral Sciences, Johns Hopkins Medical Institutions, Baltimore, MD 21287 7279, USA
Am J Geriatr Psychiatry 11:589-94. 2003..The authors used long-term follow-up and phenomenology to assess whether outcome varied by diagnosis...
Ethical issues in geriatric psychiatryPeter V Rabins
Department of Psychiatry and Behavioral Sciences, Berman Institute of Bioethics, Johns Hopkins University, Baltimore, Maryland, USA
Int Rev Psychiatry 22:267-73. 2010....
Challenges for mental health services raised by disaster preparedness: mapping the ethical and therapeutic terrainPeter V Rabins
Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 7279, USA
Biosecur Bioterror 9:175-9. 2011..In this commentary, we discuss ethical issues that arise in emergency preparedness planning for vulnerable individuals with psychological and psychiatric conditions and disorders...
MRI findings differentiate between late-onset schizophrenia and late-life mood disorderP V Rabins
Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins Medical Institutions, Baltimore 21287 7279, USA
Int J Geriatr Psychiatry 15:954-60. 2000..MRI head scans of 14 patients in each diagnostic group and 21 patients in the normal control group were compared. Subjects were recruited from inpatient and outpatient services...
Effectiveness of a nurse-based outreach program for identifying and treating psychiatric illness in the elderlyP V Rabins
Meyer 279, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21287 7279
JAMA 283:2802-9. 2000..Elderly persons with psychiatric disorders are less likely than younger adults to be diagnosed as having a mental disorder and receive needed mental health treatment. Lack of access to care is 1 possible cause of this disparity...
Effects of cardiovascular medications on rate of functional decline in Alzheimer diseaseP B Rosenberg
Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
Am J Geriatr Psychiatry 16:883-92. 2008..We examined the association of cardiovascular medication use and rate of functional decline in a population-based cohort of individuals with incident AD...
The association of psychotropic medication use with the cognitive, functional, and neuropsychiatric trajectory of Alzheimer's diseaseP B Rosenberg
Department of Psychiatry and Behavioral Sciences, Johns Hopkins Bayview Medical Center, Baltimore, MD, USA
Int J Geriatr Psychiatry 27:1248-57. 2012....
Alcohol use disorder is a risk factor for mortality among older public housing residentsB S Black
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Int Psychogeriatr 10:309-27. 1998....
Randomized, placebo-controlled, double-blind clinical trial of sertraline in the treatment of depression complicating Alzheimer's disease: initial results from the Depression in Alzheimer's Disease studyC G Lyketsos
Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, USA
Am J Psychiatry 157:1686-9. 2000..This study evaluated the efficacy and safety of sertraline in the treatment of major depression in 22 outpatients with Alzheimer's disease...
Identification of community-residing individuals with dementia and their unmet needs for careD Johnston
Division of Geriatric Psychiatry and Neuropsychiatry, The Johns Hopkins University School of Medicine, 550 North Broadway Suite 308, Baltimore, Maryland, USA
Int J Geriatr Psychiatry 26:292-8. 2011....
Dementia in elderly persons in a general hospitalC G Lyketsos
Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Johns Hopkins Hospital, Baltimore, MD 21287, USA
Am J Psychiatry 157:704-7. 2000..This study investigated the prevalence of dementia in a general hospital, reasons for which patients with dementia were admitted, and the relationship between dementia and length of stay, cost, and in-hospital mortality rate...
Dementia in hippocampal sclerosis resembles frontotemporal dementia more than Alzheimer diseaseD M Blass
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Neurology 63:492-7. 2004..To characterize the clinical course of pathologically diagnosed hippocampal sclerosis dementia (HSD)...
Predictors of nursing home placement among elderly public housing residentsB S Black
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD 21287 7279, USA
Gerontologist 39:559-68. 1999..Thus, functional status and mental morbidity are major contributors to nursing home placement in this setting...
Vascular factors predict rate of progression in Alzheimer diseaseM M Mielke
Johns Hopkins University School of Medicine, Department of Psychiatry, Division of Geriatric Psychiatry and Behavioral Sciences, 550 N Broadway, Suite 308, Baltimore, MD 21205, USA
Neurology 69:1850-8. 2007..While there is considerable epidemiologic evidence that cardiovascular risk factors increase risk of incident Alzheimer disease (AD), few studies have examined their effect on progression after an established AD diagnosis...
Clinical diagnosis of dementia, not behavioral and psychologic symptoms, is associated with psychotropic drug use in community-dwelling elders classified as having dementiaDing Chen Chan
Harvard Geriatric Medicine Fellowship Program, Boston, Massachusetts, USA
J Geriatr Psychiatry Neurol 20:100-6. 2007..Most community-dwelling elders meeting the research criteria for dementia were not clinically diagnosed, despite contact with a physician (89%) in the previous year...
Clinical diagnosis of dementia, not presence of behavioral and psychological symptoms, is associated with psychotropic use in community-dwelling elders classified as having dementiaDing Cheng Chan
Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
J Geriatr Psychiatry Neurol 20:50-7. 2007..In addition, most community-dwelling elders meeting the research criteria for dementia were not clinically diagnosed, despite contact with a physician (89%) in the previous year...
Level of cognitive impairment predicts mortality in high-risk community samples: the memory and medical care studyHochang B Lee
The Johns Hopkins University School of Medicine, 550 N Broadway, Suite 308, Baltimore, MD 21205, USA
J Neuropsychiatry Clin Neurosci 18:543-6. 2006..Kaplan-Meier survival estimates and Cox hazard proportion analysis of the sample revealed that presence of cognitive impairment increases mortality in a fashion that parallels the severity of the impairment...
Health problems and correlates of pain in nursing home residents with advanced dementiaBetty S Black
The Johns Hopkins Medical Institutions Baltimore, MD 21287, USA
Alzheimer Dis Assoc Disord 20:283-90. 2006..These results suggest the need for clinicians in long-term care facilities to be vigilant in assessing and treating pain, particularly as cognitive function declines in those with advanced dementia...
Design of Depression in Alzheimer's Disease Study-2Barbara K Martin
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Am J Geriatr Psychiatry 14:920-30. 2006....
Cholinesterase inhibitors and memantine have a role in the treatment of Alzheimer's diseasePeter V Rabins
Johns Hopkins University School of Medicine and Bloomberg School of Public Health, Baltimore, MD 21287, USA
Nat Clin Pract Neurol 2:578-9. 2006
Psychiatric and neuropsychiatric adverse events associated with deep brain stimulation: A meta-analysis of ten years' experienceBrian S Appleby
Department of Psychiatry, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Mov Disord 22:1722-8. 2007..Because of the high suicide rate, patients should be prescreened for suicide risk prior to DBS surgery. Additionally, patients should be monitored closely for suicidal behavior post-operatively...
Psychiatric manifestations of neurologic disease: where are we headed?Constantin G Lyketsos
Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry, Johns Hopkins Bayview, Baltimore, MD 21224, USA
Dialogues Clin Neurosci 9:111-24. 2007....
Treatment decisions regarding hospitalization and surgery for nursing home residents with advanced dementia: the CareAD StudyDonovan T Maust
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, U S A
Int Psychogeriatr 20:406-18. 2008..However, little is known about the factors that influence how surrogates make decisions for persons with late-stage dementia...
Does the presentation of Creutzfeldt-Jakob disease vary by age or presumed etiology? A meta-analysis of the past 10 yearsBrian S Appleby
The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA
J Neuropsychiatry Clin Neurosci 19:428-35. 2007....
Predictors of providing informed consent or assent for research participation in assisted living residentsBetty S Black
Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins School of Medicine, Johns Hopkins Bloomberg School of Public Health, 600 North Wolfe Street, Baltimore, MD 21287, USA
Am J Geriatr Psychiatry 16:83-91. 2008..This study's goal was to identify factors associated with providing either informed consent or assent for research in individuals at high risk for cognitive impairment...
Deciding in the best interest of clients with dementia: the experience of public guardiansHolly A Taylor
Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Berman Institute of Bioethics at Johns Hopkins University, Baltimore, Maryland, USA
J Clin Ethics 19:120-6. 2008..Ultimately, guardians took particularly difficult issues to the court and obtained a judge's opinion...
Characteristics and outcomes for assisted living residents with dementia: comparing dementia-specific care units with non-dementia-specific care unitsQuincy M Samus
J Am Geriatr Soc 56:1361-3. 2008
Informed consent for dementia research: the study enrollment encounterBetty S Black
Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD, USA
IRB 29:7-14. 2007
Correlates of caregiver-rated quality of life in assisted living: the Maryland Assisted Living studyQuincy M Samus
The Johns Hopkins School of Medicine, 550 North Broadway, Baltimore, MD 21205, USA
J Gerontol B Psychol Sci Soc Sci 61:P311-4. 2006..Because of the strong association of neuropsychiatric symptoms with QOL, special attention should be given to their recognition and amelioration...
Factors related to hospitalization in elderly manic patients with early and late-onset bipolar disorderSusan W Lehmann
The Johns Hopkins University School of Medicine, Baltimore, MD 21287 7279, USA
Int J Geriatr Psychiatry 21:1060-4. 2006..To identify factors contributing to relapse and hospitalization in elderly patients with bipolar disorder...
Sleep disturbances in the elderly residing in assisted living: findings from the Maryland Assisted Living StudyVani Rao
Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA
Int J Geriatr Psychiatry 20:956-66. 2005..Common sleep disturbances are insomnia and excessive daytime sleepiness. There are no published studies on the prevalence of sleep disturbance in the assisted living (AL) setting...
Population-based study of medical comorbidity in early dementia and "cognitive impairment, no dementia (CIND)": association with functional and cognitive impairment: The Cache County StudyConstantine G Lyketsos
Division of Geriatric Psychiatry and Neuropsychiatry, Dept of Psychiatry and Behavioral Sciences, School of Medicine, The Johns Hopkins University, Johns Hopkins Hospital, Baltimore, MD 21287, USA
Am J Geriatr Psychiatry 13:656-64. 2005..Authors investigated medical comorbidity in persons with dementia and "Cognitive Impairment, No Dementia" (CIND)...
Clinical application of operationalized criteria for 'Depression of Alzheimer's Disease'Paul B Rosenberg
Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Int J Geriatr Psychiatry 20:119-27. 2005..Criteria for the diagnosis of dAD have been proposed previously...
The Maryland Assisted Living Study: prevalence, recognition, and treatment of dementia and other psychiatric disorders in the assisted living population of central MarylandAdam Rosenblatt
Division of Geriatric Psychiatry and Neuropsychiatry, John Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Am Geriatr Soc 52:1618-25. 2004..To obtain a direct estimate of the prevalence of dementia and other psychiatric disorders in residents of assisted living (AL) in Central Maryland, and their rates of recognition and treatment...
Cognitive response to pharmacological treatment for depression in Alzheimer disease: secondary outcomes from the depression in Alzheimer's disease study (DIADS)Cynthia A Munro
Division of Medical Psychology, Department of Psychiatry and Behavioral Sciences, School of Medicine, The Johns Hopkins University, Baltimore, MD, USA
Am J Geriatr Psychiatry 12:491-8. 2004..The authors assessed the cognitive effects of depression treatment with sertraline in patients with Alzheimer disease (AD) and major depression...
The relationship between a dementia diagnosis, chronic illness, medicare expenditures, and hospital useJulie P W Bynum
Division of Geriatric Medicine and Gerontology, School of Medicine Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
J Am Geriatr Soc 52:187-94. 2004..To determine whether dementia increases medical expenditures, the probability of hospitalization, and potentially preventable hospitalization, controlling for variables including age and comorbidity...
Treating depression in Alzheimer disease: efficacy and safety of sertraline therapy, and the benefits of depression reduction: the DIADSConstantine G Lyketsos
Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, The Johns Hopkins University, Baltimore, MD, USA
Arch Gen Psychiatry 60:737-46. 2003..Results of prior antidepressant treatment studies have produced contradictory findings and have not fully assessed the benefits of depression reduction...
Presence of behavioral and psychological symptoms predicts nursing home placement in community-dwelling elders with cognitive impairment in univariate but not multivariate analysisDing Cheng Chan
Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
J Gerontol A Biol Sci Med Sci 58:548-54. 2003..The role of behavioral and psychological symptoms as an independent risk factor of nursing home placement (NHP) in cognitively impaired elders has been controversial...
Identifying dementia in high-risk community samples: the memory and medical care studyBetty Smith Black
Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Alzheimer Dis Assoc Disord 17:9-18. 2003..62, 95% confidence interval = 0.45-0.78). The methods used in the MMCS are efficient and reasonably valid for establishing a cohort of subjects to investigate how dementia is assessed, diagnosed, and treated in the community...
Prevalence and correlates of behavioral and psychiatric symptoms in community-dwelling elders with dementia or mild cognitive impairment: the Memory and Medical Care StudyDing Cheng Chan
Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Int J Geriatr Psychiatry 18:174-82. 2003..Little is known about the prevalence and correlates of behavioral and psychiatric symptoms of dementia in community-dwelling elders with dementia or mild cognitive impairment (MCI)...
Hospice care in a cohort of elders with dementia and mild cognitive impairmentDavid B Bekelman
Department of Medicine, Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Pain Symptom Manage 30:208-14. 2005..35; 95% CI 0.13-0.96). In this cohort of people with dementia and MCI who died, several markers of quality of care suggest that hospice care can be beneficial for patients with dementia or MCI...
The association of neuropsychiatric symptoms and environment with quality of life in assisted living residents with dementiaQuincy M Samus
Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA
Gerontologist 45:19-26. 2005..We conducted this study to determine whether neuropsychiatric symptoms and environmental characteristics are associated with quality of life in assisted living residents with dementia...
Measuring quality of life in dementia: purposes, goals, challenges and progressPeter V Rabins
Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, and The Johns Hopkins Hospital, Baltimore, MD 21287, USA
Int Psychogeriatr 19:401-7. 2007
Transition to nursing home from assisted living is not associated with dementia or dementia-related problem behaviorsPaul B Rosenberg
Department of Psychiatry and Behavioral Sciences, Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins School of Medicine, Osler 320, 600 North Wolfe Street, Baltimore, MD, USA
J Am Med Dir Assoc 7:73-8. 2006..To examine risk factors for transition from assisted living (AL) care to skilled nursing facility (SNF) care in a random sample of adults residing in AL...
Comparison of three rating scales as outcome measures for treatment trials of depression in Alzheimer disease: findings from DIADSLawrence S Mayer
Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA
Int J Geriatr Psychiatry 21:930-6. 2006..The pattern for the other subscales was non-monotonic over waves and resembled the pattern for the entire scale. Perhaps combining the CSDD two subscales obscures the treatment effects for the separate subscales...
Predictors of caregiver unawareness and nontreatment of dementia among residents of assisted living facilities: the Maryland Assisted Living StudyDonovan T Maust
Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Am J Geriatr Psychiatry 14:668-75. 2006..These observations suggest that systematic educational interventions for caregivers and families may improve detection and hence treatment in the AL setting...
Onset of schizophrenia at age 100Ana Natasha Cervantes
Dept of Psychiatry, Johns Hopkins Hospital, Baltimore, MD, USA
Psychosomatics 47:356-9. 2006..Authors discuss the differential diagnosis of psychotic symptoms presenting late in life...
Brief report: patient cognitive status and the identification and management of depression by primary care physiciansMonica K Crane
Geriatrics Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
J Gen Intern Med 21:1042-4. 2006..No known study has examined the role of patients' cognitive impairment in the identification and management of depression by primary care physicians...
Ethical issues in mobile psychiatric treatment with homebound elderly patients: the Psychogeriatric Assessment and Treatment in City Housing experienceDavid M Blass
Department of Psychiatry and Behavioral Sciences, Phoebe R Berman Bioethics Institute, Johns Hopkins Hospital, 60 North Wolfe Street, Baltimore, MD 21287, USA
J Am Geriatr Soc 54:843-8. 2006..Ethical challenges with homebound elderly patients are unique because of patient characteristics as well as features of the treatment environment...
Qualitative research in psychogeriatricsBetty S Black
Int Psychogeriatr 19:167-73. 2007
Suicidality in older African Americans: findings from the EPOCH studyJoan M Cook
University of Pennsylvania and Philadelphia VA Medical Center, 19104, USA
Am J Geriatr Psychiatry 10:437-46. 2002..The authors discuss implications of these findings and offer suggestions for research and clinical practice...
Antipsychotic drugs in dementia: what should be made of the risks?Peter V Rabins
JAMA 294:1963-5. 2005
Pathophysiology of involuntary emotional expression disorderPeter V Rabins
Division of Geriatric and Neuropsychiatry, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
CNS Spectr 12:17-22. 2007..Pharmacologic interventions targeting the neurochemical modulators of the emotional expression systems may afford opportunities for symptom control among persons affected by this disorder...
In the clinic. DementiaDavid M Blass
Ann Intern Med 148:ITC4-1-ITC4-16. 2008
American Psychiatric Association practice guideline for the treatment of patients with Alzheimer's disease and other dementias. Second editionPeter V Rabins
Am J Psychiatry 164:5-56. 2007
Pharmacotherapy of neuropsychiatric symptoms: opportunities, challenges and current prospectsPeter V Rabins
Nat Clin Pract Neurol 3:239. 2007
Personal characteristics of older primary care patients who provide a buccal swab for apolipoprotein E testing and banking of genetic material: the spectrum studyHillary R Bogner
Department of Family Practice and Community Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Community Genet 7:202-10. 2004..To determine the personal characteristics and reasons associated with providing a buccal swab for apolipoprotein E (APOE) genetic testing in a primary care study...
Patient characteristics associated with participation in a practice-based study of depression in late life: the Spectrum studyJoseph J Gallo
Department of Family Practice and Community Medicine, University of Pennsylvania, Philadelphia 19104, USA
Int J Psychiatry Med 35:41-57. 2005..The Spectrum study of depression in older primary care patients was utilized to consider patient characteristics associated with nonparticipation...
Provisional diagnostic criteria for depression of Alzheimer diseaseJason T Olin
Adult and Geriatric Treatment and Preventive Interventions Research Branch, National Institute of Mental Health, Bethesda, MD 20892 9635, USA
Am J Geriatr Psychiatry 10:125-8. 2002....
Research Grants
- END OF LIFE CARE IN LATE STAGE DEMENTIAPeter Rabins; Fiscal Year: 2004..Findings from this study will be of use in developing interventions to improve the quality of EOL care in dementia. ..
