Irfan A Qureshi

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Epigenetic mechanisms governing the process of neurodegeneration
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
    Mol Aspects Med 34:875-82. 2013
  2. pmc Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, New York 10461, USA
    Nat Rev Neurosci 13:528-41. 2012
  3. pmc Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
    Neurobiol Dis 39:53-60. 2010
  4. pmc Non-coding RNA networks underlying cognitive disorders across the lifespan
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
    Trends Mol Med 17:337-46. 2011
  5. doi request reprint Advances in epigenetics and epigenomics for neurodegenerative diseases
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Curr Neurol Neurosci Rep 11:464-73. 2011
  6. pmc Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation
    Tim R Mercer
    Institute for Molecular Bioscience, University of Queensland, 306 Carmody Road, Brisbane, QLD 4072, Australia
    BMC Neurosci 11:14. 2010
  7. pmc Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions
    Joseph J Abrajano
    Institute for Brain Disorders and Neural Regeneration, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Proc Natl Acad Sci U S A 107:16685-90. 2010
  8. pmc Towards a 'systems'-level understanding of the nervous system and its disorders
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA Institute for Brain Disorders and Neural Regeneration, Albert Einstein College of Medicine, Bronx, NY 10461, USA Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA Rose F Kennedy Center for Research on Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Trends Neurosci 36:674-84. 2013
  9. pmc REST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine Albert Einstein College of Medicine, Bronx, NY, USA
    Cell Cycle 9:4477-86. 2010
  10. pmc Emerging role of epigenetics in stroke: part 1: DNA methylation and chromatin modifications
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Institute for Brain Disorders and Neural Regeneration, and Rose F Kennedy Center for Research on Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Arch Neurol 67:1316-22. 2010

Collaborators

Detail Information

Publications23

  1. pmc Epigenetic mechanisms governing the process of neurodegeneration
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
    Mol Aspects Med 34:875-82. 2013
    ....
  2. pmc Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, New York 10461, USA
    Nat Rev Neurosci 13:528-41. 2012
    ..This expanding inventory of ncRNAs is implicated in mediating a broad spectrum of processes including brain evolution, development, synaptic plasticity and disease pathogenesis...
  3. pmc Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
    Neurobiol Dis 39:53-60. 2010
    ..g., RELN), and diverse transcriptional regulators (e.g., CREB, c-fos, and c-jun). These important observations suggest that future epigenetic studies are necessary to better understand, classify, prevent, and treat epileptic disorders...
  4. pmc Non-coding RNA networks underlying cognitive disorders across the lifespan
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
    Trends Mol Med 17:337-46. 2011
    ....
  5. doi request reprint Advances in epigenetics and epigenomics for neurodegenerative diseases
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Curr Neurol Neurosci Rep 11:464-73. 2011
    ....
  6. pmc Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation
    Tim R Mercer
    Institute for Molecular Bioscience, University of Queensland, 306 Carmody Road, Brisbane, QLD 4072, Australia
    BMC Neurosci 11:14. 2010
    ..Long non-protein-coding RNAs (ncRNAs) are emerging as important regulators of cellular differentiation and are widely expressed in the brain...
  7. pmc Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions
    Joseph J Abrajano
    Institute for Brain Disorders and Neural Regeneration, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Proc Natl Acad Sci U S A 107:16685-90. 2010
    ..Clonal NSC REST and CoREST gene manipulation paradigms further revealed that CoREST has largely independent and previously uncharacterized roles in promoting NSC multilineage potential and modulating early neural fate decisions...
  8. pmc Towards a 'systems'-level understanding of the nervous system and its disorders
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA Institute for Brain Disorders and Neural Regeneration, Albert Einstein College of Medicine, Bronx, NY 10461, USA Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA Rose F Kennedy Center for Research on Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Trends Neurosci 36:674-84. 2013
    ....
  9. pmc REST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine Albert Einstein College of Medicine, Bronx, NY, USA
    Cell Cycle 9:4477-86. 2010
    ..These observations support the conclusion that REST and CoREST act as master regulators of key neural cell fate decisions...
  10. pmc Emerging role of epigenetics in stroke: part 1: DNA methylation and chromatin modifications
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Institute for Brain Disorders and Neural Regeneration, and Rose F Kennedy Center for Research on Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Arch Neurol 67:1316-22. 2010
    ..Indeed, these agents even appear to orchestrate sophisticated cognitive functions, including learning and memory...
  11. doi request reprint Genetic and epigenetic underpinnings of sex differences in the brain and in neurological and psychiatric disease susceptibility
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
    Prog Brain Res 186:77-95. 2010
    ..These emerging findings also suggest that epigenetic mechanisms are, in part, responsible for the differential susceptibility between males and females that is characteristic of a spectrum of neurological and psychiatric disorders...
  12. pmc Impact of nuclear organization and dynamics on epigenetic regulation in the central nervous system: implications for neurological disease states
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Ann N Y Acad Sci 1204:E20-37. 2010
    ....
  13. pmc Developing epigenetic diagnostics and therapeutics for brain disorders
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA Institute for Brain Disorders and Neural Regeneration, Albert Einstein College of Medicine, Bronx, NY 10461, USA Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA Rose F Kennedy Center for Research on Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Trends Mol Med 19:732-41. 2013
    ....
  14. pmc Long non-coding RNAs in nervous system function and disease
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Brain Res 1338:20-35. 2010
    ....
  15. pmc Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation
    Joseph J Abrajano
    Institute for Brain Disorders and Neural Regeneration, Albert Einstein College of Medicine, Bronx, New York, United States of America
    PLoS ONE 4:e7665. 2009
    ..Despite their involvement in multiple aspects of neuronal development, REST and CoREST are not believed to have any direct modulatory roles in glial cell maturation...
  16. pmc Long non-coding RNAs: novel targets for nervous system disease diagnosis and therapy
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
    Neurotherapeutics 10:632-46. 2013
    ..Such clinical applications are in the early stages of development but are rapidly advancing because of existing expertise and technology platforms that are readily adaptable for these purposes. ..
  17. doi request reprint Understanding neurological disease mechanisms in the era of epigenetics
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, New York 10461, USA
    JAMA Neurol 70:703-10. 2013
    ....
  18. pmc The emerging role of epigenetics in stroke: II. RNA regulatory circuitry
    Irfan A Qureshi
    Institute for Brain Disorders and Neural Regeneration, Department of Neurology, Rose F Kennedy Center for Research on Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Arch Neurol 67:1435-41. 2010
    ....
  19. doi request reprint Epigenetics of sleep and chronobiology
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY, 10461, USA
    Curr Neurol Neurosci Rep 14:432. 2014
    ....
  20. ncbi request reprint Alu transcription: a rheostat for stem cell aging?
    Irfan A Qureshi
    Albert Einstein College of Medicine, Bronx, NY, USA
    Cell Cycle 10:3820-1. 2011
  21. pmc The emerging role of epigenetics in stroke: III. Neural stem cell biology and regenerative medicine
    Irfan A Qureshi
    Roslyn and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Institute for Brain Disorders and Neural Regeneration, Department of Neurology, Rose F Kennedy Center, Albert Einstein College of Medicine, 1410 Pelham Pkwy S, Room 220, Bronx, NY 10461, USA
    Arch Neurol 68:294-302. 2011
    ....
  22. pmc Regulation of non-coding RNA networks in the nervous system--what's the REST of the story?
    Irfan A Qureshi
    Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Neurosci Lett 466:73-80. 2009
    ..This review summarizes emerging aspects of the complex mechanistic relationships between these intricately interlaced control systems for neural gene expression and function...