Naresh Punjabi

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Sleep-disordered breathing and caffeine consumption: results of a community-based study
    R Nisha Aurora
    Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Chest 142:631-8. 2012
  2. ncbi request reprint Measurement variability in single-breath diffusing capacity of the lung
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Chest 123:1082-9. 2003
  3. pmc Sleep-disordered breathing and cardiovascular disease: an outcome-based definition of hypopneas
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Am J Respir Crit Care Med 177:1150-5. 2008
  4. ncbi request reprint Elevated levels of neopterin in sleep-disordered breathing
    Naresh M Punjabi
    Johns Hopkins University, Division of Pulmonary and Critical Care Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Chest 132:1124-30. 2007
  5. pmc Alterations in Glucose Disposal in Sleep-disordered Breathing
    Naresh M Punjabi
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Respir Crit Care Med 179:235-40. 2009
  6. ncbi request reprint Cigarette smoking and nocturnal sleep architecture
    Lin Zhang
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21224, USA
    Am J Epidemiol 164:529-37. 2006
  7. ncbi request reprint Disorders of glucose metabolism in sleep apnea
    Naresh M Punjabi
    Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    J Appl Physiol (1985) 99:1998-2007. 2005
  8. pmc The epidemiology of adult obstructive sleep apnea
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Proc Am Thorac Soc 5:136-43. 2008
  9. ncbi request reprint Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD21224, USA
    Am J Epidemiol 160:521-30. 2004
  10. pmc Sleep-disordered breathing and mortality: a prospective cohort study
    Naresh M Punjabi
    Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS Med 6:e1000132. 2009

Detail Information

Publications47

  1. pmc Sleep-disordered breathing and caffeine consumption: results of a community-based study
    R Nisha Aurora
    Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Chest 142:631-8. 2012
    ..The current study examined whether SDB is associated with caffeine consumption and if factors such as sex, age, and daytime sleepiness explain or modify the association...
  2. ncbi request reprint Measurement variability in single-breath diffusing capacity of the lung
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Chest 123:1082-9. 2003
    ..The objectives of the present study were to examine whether the current reproducibility criteria were met in a general pulmonary function laboratory and to determine whether alternative criteria might be appropriate...
  3. pmc Sleep-disordered breathing and cardiovascular disease: an outcome-based definition of hypopneas
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Am J Respir Crit Care Med 177:1150-5. 2008
    ..Although hypopneas constitute a majority of disordered breathing events, significant controversy remains about the best criteria used to define these events...
  4. ncbi request reprint Elevated levels of neopterin in sleep-disordered breathing
    Naresh M Punjabi
    Johns Hopkins University, Division of Pulmonary and Critical Care Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Chest 132:1124-30. 2007
    ..Thus, this investigation sought to determine whether neopterin, a marker released by activated macrophages, is increased in SDB...
  5. pmc Alterations in Glucose Disposal in Sleep-disordered Breathing
    Naresh M Punjabi
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Respir Crit Care Med 179:235-40. 2009
    ..However, data on whether SDB alters in vivo kinetics of glucose and insulin are lacking...
  6. ncbi request reprint Cigarette smoking and nocturnal sleep architecture
    Lin Zhang
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21224, USA
    Am J Epidemiol 164:529-37. 2006
    ..Nicotine in cigarette smoke and acute withdrawal from it may contribute to disturbances in sleep architecture...
  7. ncbi request reprint Disorders of glucose metabolism in sleep apnea
    Naresh M Punjabi
    Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    J Appl Physiol (1985) 99:1998-2007. 2005
    ....
  8. pmc The epidemiology of adult obstructive sleep apnea
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Proc Am Thorac Soc 5:136-43. 2008
    ..The primary objective of this article is to review some of the epidemiologic aspects of obstructive sleep apnea in adults...
  9. ncbi request reprint Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD21224, USA
    Am J Epidemiol 160:521-30. 2004
    ..The results of this study suggest that SDB is independently associated with glucose intolerance and insulin resistance and may lead to type 2 diabetes mellitus...
  10. pmc Sleep-disordered breathing and mortality: a prospective cohort study
    Naresh M Punjabi
    Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS Med 6:e1000132. 2009
    ....
  11. ncbi request reprint Sleep-disordered breathing, glucose intolerance, and insulin resistance
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Respir Physiol Neurobiol 136:167-78. 2003
    ..Potential mediators of this association include altered adrenergic function, the direct effects of hypoxemia on glucose regulation, and release of proinflammatory cytokines that affect metabolism...
  12. ncbi request reprint Predictors of objective sleep tendency in the general population
    Naresh M Punjabi
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Sleep 26:678-83. 2003
    ....
  13. pmc Fasting glycemia in sleep disordered breathing: lowering the threshold on oxyhemoglobin desaturation
    Katherine Stamatakis
    Johns Hopkins University, Baltimore, MD, USA
    Sleep 31:1018-24. 2008
    ..However, it is not known whether disordered breathing events with oxyhemoglobin desaturation less than 4% are associated with clinical sequelae such as abnormalities in fasting glycemia...
  14. pmc Characterizing sleep structure using the hypnogram
    Bruce J Swihart
    Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA
    J Clin Sleep Med 4:349-55. 2008
    ..The primary objective of this investigation was to demonstrate the utility of log-linear and multistate analysis of the sleep hypnogram in evaluating differences in nocturnal sleep structure in subjects with and without SDB...
  15. pmc Effects of acute intermittent hypoxia on glucose metabolism in awake healthy volunteers
    Mariam Louis
    Div of Pulmonary and Critical Care Medicine, Johns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    J Appl Physiol (1985) 106:1538-44. 2009
    ..Hypoxic stress in obstructive sleep apnea may increase the predisposition for metabolic dysfunction by impairing insulin sensitivity, glucose effectiveness, and insulin secretion...
  16. pmc Contribution of male sex, age, and obesity to mechanical instability of the upper airway during sleep
    Jason P Kirkness
    Div of Pulmonary and Critical Care Medicine, The Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Appl Physiol (1985) 104:1618-24. 2008
    ..65-0.82) in predicting sleep apnea status. Upper airway mechanics are differentially controlled by sex, obesity, and age, and partly mediate the relationship between these sleep apnea risk factors and obstructive sleep apnea...
  17. ncbi request reprint Intermittent hypoxia induces hyperlipidemia in lean mice
    Jianguo Li
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Circ Res 97:698-706. 2005
    ....
  18. pmc C-reactive protein is associated with sleep disordered breathing independent of adiposity
    Naresh M Punjabi
    Johns Hopkins University, Department of Medicine, Baltimore, MD 21224, USA
    Sleep 30:29-34. 2007
    ..The present study examined the association between degree of SDB and level of CRP independent of prevalent medical conditions and obesity...
  19. pmc Cross-sectional and prospective study of lung function in adults with type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study
    Hsin Chieh Yeh
    Department of Epidemiology, The Johns Hopkins University, Baltimore, Maryland 21205, USA
    Diabetes Care 31:741-6. 2008
    ..The aim of this study was to test the hypothesis that diabetes is independently associated with reduced lung function, both cross-sectionally and longitudinally...
  20. ncbi request reprint The association between daytime sleepiness and sleep-disordered breathing in NREM and REM sleep
    Naresh M Punjabi
    Sleep 25:307-14. 2002
    ....
  21. ncbi request reprint A simplified method for measuring critical pressures during sleep in the clinical setting
    Susheel P Patil
    Johns Hopkins Sleep Disorders Center, Asthma and Allergy Building, 5501 Hopkins Bayview Circle, Room 4B 50, Baltimore, MD 21224, USA
    Am J Respir Crit Care Med 170:86-93. 2004
    ....
  22. ncbi request reprint Sleep-disordered breathing and insulin resistance in middle-aged and overweight men
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, Asthma and Allergy Center, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Am J Respir Crit Care Med 165:677-82. 2002
    ..Thus, sleep-disordered breathing is a prevalent condition in mildly obese men and is independently associated with glucose intolerance and insulin resistance...
  23. ncbi request reprint Demographics and diagnosis of obstructive sleep apnea
    Tracey Stierer
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 601 North Caroline Street, B165A, Baltimore, Maryland 21287 0712, USA
    Anesthesiol Clin North America 23:405-20, v. 2005
    ..Patients with the disease may be at a higher risk for adverse perioperative outcomes. Knowledge of factors associated with an increased risk of obstructive sleep apnea is vital to the perioperative assessment and anesthetic plan...
  24. pmc Intermittent hypoxia increases insulin resistance in genetically obese mice
    Vsevolod Y Polotsky
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    J Physiol 552:253-64. 2003
    ..001) and worsening glucose tolerance, consistent with an increase in insulin resistance. We conclude that the increase in insulin resistance in response to intermittent hypoxia is dependent on the disruption of leptin pathways...
  25. ncbi request reprint Relationship between lung function and physical performance in disabled older women
    Crystal F Simpson
    MHS, Center on Aging and Health and Division of Geriatric Medicine, The Johns Hopkins School of Medicne, Baltimore, Maryland 21205, USA
    J Gerontol A Biol Sci Med Sci 60:350-4. 2005
    ..The aim of this study was to determine the association of lung function with objective and self-reported physical performance in community-dwelling disabled older women...
  26. pmc Effects of sleep fragmentation on glucose metabolism in normal subjects
    Katherine A Stamatakis
    Department of Epidemiology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Chest 137:95-101. 2010
    ..The objective of this study was to examine whether experimental sleep fragmentation across all sleep stages would alter glucose metabolism, adrenocortical function, and sympathovagal balance...
  27. ncbi request reprint Differences in patient and bed partner-assessed quality of life in sleep-disordered breathing
    J Gabrielle Breugelmans
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21224, USA
    Am J Respir Crit Care Med 170:547-52. 2004
    ..This study suggests that systematic differences exist between patient- and bed partner-assessed quality of life in SDB. Bed partner ratings provide supplemental information on quality of life impairment in SDB...
  28. pmc Serum levels of the immune activation marker neopterin change with age and gender and are modified by race, BMI, and percentage of body fat
    Monique E Spencer
    Biology of Frailty Program, Division of Geriatric Medicine and Gerontology, Johns Hopkins University, Baltimore, Maryland, USA
    J Gerontol A Biol Sci Med Sci 65:858-65. 2010
    ..In addition to age, we assessed gender, race, body mass index (BMI), and percentage of body fat (%fat) as potential covariates...
  29. ncbi request reprint Vital capacity as a predictor of incident type 2 diabetes: the Atherosclerosis Risk in Communities study
    Hsin Chieh Yeh
    The Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, 2024 E Monument St, Suite 2 600, Baltimore, MD 21205, USA
    Diabetes Care 28:1472-9. 2005
    ..To test the hypothesis that lower vital capacity is cross-sectionally associated with features of insulin resistance and is an independent predictor of incident type 2 diabetes...
  30. doi request reprint Do sleep disorders and associated treatments impact glucose metabolism?
    Naresh M Punjabi
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21224, USA
    Drugs 69:13-27. 2009
    ..In conclusion, there is limited evidence on whether sleep disorders alter glucose metabolism and whether treatment can reduce the excess metabolic risk...
  31. pmc Bootstrap-based inference on the difference in the means of two correlated functional processes
    Ciprian M Crainiceanu
    Department of Biostatistics, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD 21205, U S A
    Stat Med 31:3223-40. 2012
    ..We obtain data from the Sleep Heart Health Study, the largest community cohort study of sleep. Although methods are applied to a single case study, they can be applied to a large number of studies that have correlated functional data...
  32. doi request reprint Power spectral analysis of the sleep electroencephalogram in heartburn patients with or without gastroesophageal reflux disease: a feasibility study
    Rohit Budhiraja
    Section of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Neuroenteric Clinical Research Group, Southern Arizona VA Health Care System, University of Arizona Health Sciences Center, Tucson, AZ, USA
    J Clin Gastroenterol 44:91-6. 2010
    ..Determine the feasibility of using power spectrum of the sleep electroencephalogram (EEG) as a more sensitive tool than sleep architecture to evaluate the relationship between gastroesophageal reflux disease (GERD) and sleep...
  33. ncbi request reprint Power spectral analysis of EEG activity during sleep in cigarette smokers
    Lin Zhang
    Department of Epidemiology, Johns Hopkins University Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD 2122, USA
    Chest 133:427-32. 2008
    ..Research on the effects of cigarette smoking on sleep architecture is limited. The objective of this investigation was to examine differences in sleep EEG between smokers and nonsmokers...
  34. pmc Sleep problems reported by patients entering opioid agonist treatment
    Christopher K Burke
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    J Subst Abuse Treat 35:328-33. 2008
    ....
  35. ncbi request reprint Treatment of right heart thromboemboli
    Peter S Rose
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA
    Chest 121:806-14. 2002
    ..This fact is highlighted in the case study of a patient with a 19-cm right atrial thrombus complicating bilateral pulmonary thromboemboli...
  36. ncbi request reprint Sleep and sleep-disordered breathing in adults with predominantly mild obstructive airway disease
    Mark H Sanders
    Division of Pulmonary, Allergy, and Critical Care Medicine, Montefiore University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Respir Crit Care Med 167:7-14. 2003
    ....
  37. ncbi request reprint Diabetes and sleep disturbances: findings from the Sleep Heart Health Study
    Helaine E Resnick
    MedStar Research Institute, Hyattsville, Maryland 20783, USA
    Diabetes Care 26:702-9. 2003
    ..To test the hypothesis that diabetes is independently associated with sleep-disordered breathing (SDB), and in particular that diabetes is associated with sleep abnormalities of a central, rather than obstructive, nature...
  38. ncbi request reprint Association of sleep time with diabetes mellitus and impaired glucose tolerance
    Daniel J Gottlieb
    The Pulmonary Center, Boston University School of Medicine, VA Boston Healthcare System, 715 Albany St, Mail Stop R 304, Boston, MA 02118, USA
    Arch Intern Med 165:863-7. 2005
    ....
  39. ncbi request reprint Association of usual sleep duration with hypertension: the Sleep Heart Health Study
    Daniel J Gottlieb
    The Pulmonary Center, Boston University School of Medicine, 715 Albany Street, R 304, Boston, MA 02118 2394, USA
    Sleep 29:1009-14. 2006
    ..This study assesses the relationship between usual sleep duration and hypertension in a community-based cohort...
  40. ncbi request reprint Sleep apnea in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the Sleep Heart Health Study
    Mark L Unruh
    University of Pittsburgh Medical Center, Renal Electrolyte Division, 3550 Terrace Street, A909 Scaife Hall, Pittsburgh, PA 15261, USA
    J Am Soc Nephrol 17:3503-9. 2006
    ..The potential mechanisms for the higher likelihood of SDB in the HD population must be identified to provide specific prevention and therapy...
  41. pmc Subjective and objective sleep quality in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the sleep heart health study
    Mark L Unruh
    Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    Am J Kidney Dis 52:305-13. 2008
    ..It therefore is uncertain whether poor sleep quality in the HD population reflects age, chronic health conditions, or effects of conventional HD therapy...
  42. ncbi request reprint Sleep-disordered breathing and type 2 diabetes: a report from the International Diabetes Federation Taskforce on Epidemiology and Prevention
    Jonathan E Shaw
    International Diabetes Institute, 250 Kooyong Road, Caulfield, Melbourne, VIC 3162, Australia
    Diabetes Res Clin Pract 81:2-12. 2008
    ....
  43. doi request reprint Sleep-disordered breathing and impaired glucose metabolism in normal-weight and overweight/obese individuals: the Sleep Heart Health Study
    Sinziana Seicean
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA
    Diabetes Care 31:1001-6. 2008
    ..To characterize the association between sleep-disordered breathing (SDB) and impaired fasting glucose (IFG), impaired glucose tolerance (IGT), combined IFG and IGT, and occult diabetes in individuals of different body habitus...
  44. pmc Long sleep duration: a risk to health or a marker of risk?
    Katherine A Stamatakis
    Sleep Med Rev 11:337-9. 2007
  45. ncbi request reprint Improvement of metabolic function in sleep apnea: the power of positive pressure
    Naresh M Punjabi
    Am J Respir Crit Care Med 169:139-40. 2004
  46. pmc Sleep: a nourisher in life's feast?
    Alison M Laffan
    Sleep Med Rev 12:253-5. 2008
  47. ncbi request reprint Relation of sleep-disordered breathing to carotid plaque and intima-media thickness
    Keattiyoat Wattanakit
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Suite 300, 1300 South 2nd Street, Minneapolis, MN 55454, United States
    Atherosclerosis 197:125-31. 2008
    ..Sleep-disordered breathing (SDB) is associated with clinical cardiovascular disease (CVD), but its relation to subclinical atherosclerosis remains to be determined...

Research Grants15

  1. EARLY IDENTIFICATION AND TREATMENT OF SLEEP APNEA
    Naresh Punjabi; Fiscal Year: 2003
    Dr. Naresh Punjabi is a promising young investigator who has made a substantial commitment to an academic career in clinical research...
  2. Sleep Apnea and Longitudinal Changes in Glycemia and Inflammation in Older Men
    Naresh Punjabi; Fiscal Year: 2010
    ....
  3. Mechanisms of Altered Glucose Metabolism in Sleep-Disordered Breathing
    Naresh Punjabi; Fiscal Year: 2010
    ..We will also investigate whether treatment of sleep disordered breathing with continuous positive airway pressure improves metabolic function. ..
  4. Longtitudinal Changes in Sleep Structure: Implications for Health Outcomes
    Naresh Punjabi; Fiscal Year: 2009
    ....
  5. Sleep Apnea and Longitudinal Changes in Glycemia and Inflammation in Older Men
    Naresh Punjabi; Fiscal Year: 2009
    ....
  6. Longtitudinal Changes in Sleep Structure: Implications for Health Outcomes
    Naresh Punjabi; Fiscal Year: 2007
    ....
  7. THE SLEEP HEART HEALTH STUDY
    Naresh Punjabi; Fiscal Year: 2007
    ..Accomplishing these goals will provide important information concerning the public health impact of SDB. ..
  8. Effects of aging on sleep architecture
    Naresh Punjabi; Fiscal Year: 2006
    ....
  9. The Effects of Sleep Apnea on Metabolic Function
    Naresh Punjabi; Fiscal Year: 2006
    ..abstract_text> ..
  10. The Effects of Sleep Apnea on Metabolic Function
    Naresh Punjabi; Fiscal Year: 2005
    ..abstract_text> ..
  11. The Effects of Sleep Apnea on Metabolic Function
    Naresh Punjabi; Fiscal Year: 2004
    ..abstract_text> ..
  12. Effects of Sleep Apnea on Metabolic Function
    Naresh Punjabi; Fiscal Year: 2003
    ..abstract_text> ..
  13. Longtitudinal Changes in Sleep Structure: Implications for Health Outcomes
    Naresh Punjabi; Fiscal Year: 2010
    ....