Research Topics
Species | Naresh PunjabiSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Sleep-disordered breathing and caffeine consumption: results of a community-based studyR Nisha Aurora
Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
Chest 142:631-8. 2012..The current study examined whether SDB is associated with caffeine consumption and if factors such as sex, age, and daytime sleepiness explain or modify the association...
Measurement variability in single-breath diffusing capacity of the lungNaresh M Punjabi
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
Chest 123:1082-9. 2003..The objectives of the present study were to examine whether the current reproducibility criteria were met in a general pulmonary function laboratory and to determine whether alternative criteria might be appropriate...- Sleep-disordered breathing and cardiovascular disease: an outcome-based definition of hypopneasNaresh M Punjabi
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
Am J Respir Crit Care Med 177:1150-5. 2008..Although hypopneas constitute a majority of disordered breathing events, significant controversy remains about the best criteria used to define these events... - Elevated levels of neopterin in sleep-disordered breathingNaresh M Punjabi
Johns Hopkins University, Division of Pulmonary and Critical Care Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
Chest 132:1124-30. 2007..Thus, this investigation sought to determine whether neopterin, a marker released by activated macrophages, is increased in SDB... - Alterations in Glucose Disposal in Sleep-disordered BreathingNaresh M Punjabi
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Respir Crit Care Med 179:235-40. 2009..However, data on whether SDB alters in vivo kinetics of glucose and insulin are lacking... - Cigarette smoking and nocturnal sleep architectureLin Zhang
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21224, USA
Am J Epidemiol 164:529-37. 2006..Nicotine in cigarette smoke and acute withdrawal from it may contribute to disturbances in sleep architecture... - Disorders of glucose metabolism in sleep apneaNaresh M Punjabi
Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
J Appl Physiol 99:1998-2007. 2005.... - The epidemiology of adult obstructive sleep apneaNaresh M Punjabi
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
Proc Am Thorac Soc 5:136-43. 2008..The primary objective of this article is to review some of the epidemiologic aspects of obstructive sleep apnea in adults... - Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health StudyNaresh M Punjabi
Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD21224, USA
Am J Epidemiol 160:521-30. 2004..The results of this study suggest that SDB is independently associated with glucose intolerance and insulin resistance and may lead to type 2 diabetes mellitus... - Sleep-disordered breathing and mortality: a prospective cohort studyNaresh M Punjabi
Johns Hopkins University, Baltimore, Maryland, United States of America
PLoS Med 6:e1000132. 2009.... - Sleep-disordered breathing, glucose intolerance, and insulin resistanceNaresh M Punjabi
Division of Pulmonary and Critical Care Medicine, Johns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
Respir Physiol Neurobiol 136:167-78. 2003..Potential mediators of this association include altered adrenergic function, the direct effects of hypoxemia on glucose regulation, and release of proinflammatory cytokines that affect metabolism... - Predictors of objective sleep tendency in the general populationNaresh M Punjabi
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
Sleep 26:678-83. 2003.... - Fasting glycemia in sleep disordered breathing: lowering the threshold on oxyhemoglobin desaturationKatherine Stamatakis
Johns Hopkins University, Baltimore, MD, USA
Sleep 31:1018-24. 2008..However, it is not known whether disordered breathing events with oxyhemoglobin desaturation less than 4% are associated with clinical sequelae such as abnormalities in fasting glycemia... - Characterizing sleep structure using the hypnogramBruce J Swihart
Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA
J Clin Sleep Med 4:349-55. 2008..The primary objective of this investigation was to demonstrate the utility of log-linear and multistate analysis of the sleep hypnogram in evaluating differences in nocturnal sleep structure in subjects with and without SDB... - Effects of acute intermittent hypoxia on glucose metabolism in awake healthy volunteersMariam Louis
Div of Pulmonary and Critical Care Medicine, Johns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
J Appl Physiol 106:1538-44. 2009..Hypoxic stress in obstructive sleep apnea may increase the predisposition for metabolic dysfunction by impairing insulin sensitivity, glucose effectiveness, and insulin secretion... - Contribution of male sex, age, and obesity to mechanical instability of the upper airway during sleepJason P Kirkness
Div of Pulmonary and Critical Care Medicine, The Johns Hopkins School of Medicine, Baltimore, MD, USA
J Appl Physiol 104:1618-24. 2008..65-0.82) in predicting sleep apnea status. Upper airway mechanics are differentially controlled by sex, obesity, and age, and partly mediate the relationship between these sleep apnea risk factors and obstructive sleep apnea... - Intermittent hypoxia induces hyperlipidemia in lean miceJianguo Li
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
Circ Res 97:698-706. 2005.... - C-reactive protein is associated with sleep disordered breathing independent of adiposityNaresh M Punjabi
Johns Hopkins University, Department of Medicine, Baltimore, MD 21224, USA
Sleep 30:29-34. 2007..The present study examined the association between degree of SDB and level of CRP independent of prevalent medical conditions and obesity... - Cross-sectional and prospective study of lung function in adults with type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) studyHsin Chieh Yeh
Department of Epidemiology, The Johns Hopkins University, Baltimore, Maryland 21205, USA
Diabetes Care 31:741-6. 2008..The aim of this study was to test the hypothesis that diabetes is independently associated with reduced lung function, both cross-sectionally and longitudinally... - The association between daytime sleepiness and sleep-disordered breathing in NREM and REM sleepNaresh M Punjabi
Sleep 25:307-14. 2002.... - A simplified method for measuring critical pressures during sleep in the clinical settingSusheel P Patil
Johns Hopkins Sleep Disorders Center, Asthma and Allergy Building, 5501 Hopkins Bayview Circle, Room 4B 50, Baltimore, MD 21224, USA
Am J Respir Crit Care Med 170:86-93. 2004.... - Sleep-disordered breathing and insulin resistance in middle-aged and overweight menNaresh M Punjabi
Division of Pulmonary and Critical Care Medicine, Asthma and Allergy Center, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
Am J Respir Crit Care Med 165:677-82. 2002..Thus, sleep-disordered breathing is a prevalent condition in mildly obese men and is independently associated with glucose intolerance and insulin resistance... - Demographics and diagnosis of obstructive sleep apneaTracey Stierer
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 601 North Caroline Street, B165A, Baltimore, Maryland 21287 0712, USA
Anesthesiol Clin North America 23:405-20, v. 2005..Patients with the disease may be at a higher risk for adverse perioperative outcomes. Knowledge of factors associated with an increased risk of obstructive sleep apnea is vital to the perioperative assessment and anesthetic plan... - Intermittent hypoxia increases insulin resistance in genetically obese miceVsevolod Y Polotsky
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
J Physiol 552:253-64. 2003..001) and worsening glucose tolerance, consistent with an increase in insulin resistance. We conclude that the increase in insulin resistance in response to intermittent hypoxia is dependent on the disruption of leptin pathways... - Relationship between lung function and physical performance in disabled older womenCrystal F Simpson
MHS, Center on Aging and Health and Division of Geriatric Medicine, The Johns Hopkins School of Medicne, Baltimore, Maryland 21205, USA
J Gerontol A Biol Sci Med Sci 60:350-4. 2005..The aim of this study was to determine the association of lung function with objective and self-reported physical performance in community-dwelling disabled older women... - Effects of sleep fragmentation on glucose metabolism in normal subjectsKatherine A Stamatakis
Department of Epidemiology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
Chest 137:95-101. 2010..The objective of this study was to examine whether experimental sleep fragmentation across all sleep stages would alter glucose metabolism, adrenocortical function, and sympathovagal balance... - Differences in patient and bed partner-assessed quality of life in sleep-disordered breathingJ Gabrielle Breugelmans
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21224, USA
Am J Respir Crit Care Med 170:547-52. 2004..This study suggests that systematic differences exist between patient- and bed partner-assessed quality of life in SDB. Bed partner ratings provide supplemental information on quality of life impairment in SDB... - Serum levels of the immune activation marker neopterin change with age and gender and are modified by race, BMI, and percentage of body fatMonique E Spencer
Biology of Frailty Program, Division of Geriatric Medicine and Gerontology, Johns Hopkins University, Baltimore, Maryland, USA
J Gerontol A Biol Sci Med Sci 65:858-65. 2010..In addition to age, we assessed gender, race, body mass index (BMI), and percentage of body fat (%fat) as potential covariates... - Vital capacity as a predictor of incident type 2 diabetes: the Atherosclerosis Risk in Communities studyHsin-Chieh Yeh
The Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, 2024 E. Monument St, Suite 2-600, Baltimore, MD 21205, USA
Diabetes Care 28:1472-9. 2005..CONCLUSIONS: Lower vital capacity is an independent predictor of incident type 2 diabetes. Pulmonary factors related to vital capacity deserve attention as possible risk factors for insulin resistance and diabetes... 
Do sleep disorders and associated treatments impact glucose metabolism?Naresh M Punjabi
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21224, USA
Drugs 69:13-27. 2009..In conclusion, there is limited evidence on whether sleep disorders alter glucose metabolism and whether treatment can reduce the excess metabolic risk...- Bootstrap-based inference on the difference in the means of two correlated functional processesCiprian M Crainiceanu
Department of Biostatistics, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD 21205, U S A
Stat Med 31:3223-40. 2012..We obtain data from the Sleep Heart Health Study, the largest community cohort study of sleep. Although methods are applied to a single case study, they can be applied to a large number of studies that have correlated functional data... - Power spectral analysis of the sleep electroencephalogram in heartburn patients with or without gastroesophageal reflux disease: a feasibility studyRohit Budhiraja
Section of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Neuroenteric Clinical Research Group, Southern Arizona VA Health Care System, University of Arizona Health Sciences Center, Tucson, AZ, USA
J Clin Gastroenterol 44:91-6. 2010..Determine the feasibility of using power spectrum of the sleep electroencephalogram (EEG) as a more sensitive tool than sleep architecture to evaluate the relationship between gastroesophageal reflux disease (GERD) and sleep... - Power spectral analysis of EEG activity during sleep in cigarette smokersLin Zhang
Department of Epidemiology, Johns Hopkins University Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Baltimore, MD 2122, USA
Chest 133:427-32. 2008..Research on the effects of cigarette smoking on sleep architecture is limited. The objective of this investigation was to examine differences in sleep EEG between smokers and nonsmokers... - Sleep problems reported by patients entering opioid agonist treatmentChristopher K Burke
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
J Subst Abuse Treat 35:328-33. 2008.... - Treatment of right heart thromboemboliPeter S Rose
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA
Chest 121:806-14. 2002..A well-designed prospective, randomized trial is needed to determine the optimal treatment of right heart thromboemboli... - Sleep and sleep-disordered breathing in adults with predominantly mild obstructive airway diseaseMark H Sanders
Division of Pulmonary, Allergy, and Critical Care Medicine, Montefiore University Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Am J Respir Crit Care Med 167:7-14. 2003.... - Diabetes and sleep disturbances: findings from the Sleep Heart Health StudyHelaine E Resnick
MedStar Research Institute, Hyattsville, Maryland 20783, USA
Diabetes Care 26:702-9. 2003..To test the hypothesis that diabetes is independently associated with sleep-disordered breathing (SDB), and in particular that diabetes is associated with sleep abnormalities of a central, rather than obstructive, nature... - Association of sleep time with diabetes mellitus and impaired glucose toleranceDaniel J Gottlieb
The Pulmonary Center, Boston University School of Medicine, VA Boston Healthcare System, 715 Albany St, Mail Stop R 304, Boston, MA 02118, USA
Arch Intern Med 165:863-7. 2005.... - Association of usual sleep duration with hypertension: the Sleep Heart Health StudyDaniel J Gottlieb
The Pulmonary Center, Boston University School of Medicine, 715 Albany Street, R 304, Boston, MA 02118 2394, USA
Sleep 29:1009-14. 2006..This study assesses the relationship between usual sleep duration and hypertension in a community-based cohort... - Sleep apnea in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the Sleep Heart Health StudyMark L Unruh
University of Pittsburgh Medical Center, Renal Electrolyte Division, 3550 Terrace Street, A909 Scaife Hall, Pittsburgh, PA 15261, USA
J Am Soc Nephrol 17:3503-9. 2006..The potential mechanisms for the higher likelihood of SDB in the HD population must be identified to provide specific prevention and therapy... - Subjective and objective sleep quality in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the sleep heart health studyMark L Unruh
Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
Am J Kidney Dis 52:305-13. 2008..It therefore is uncertain whether poor sleep quality in the HD population reflects age, chronic health conditions, or effects of conventional HD therapy... - Sleep-disordered breathing and type 2 diabetes: a report from the International Diabetes Federation Taskforce on Epidemiology and PreventionJonathan E Shaw
International Diabetes Institute, 250 Kooyong Road, Caulfield, Melbourne, VIC 3162, Australia
Diabetes Res Clin Pract 81:2-12. 2008.... - Sleep-disordered breathing and impaired glucose metabolism in normal-weight and overweight/obese individuals: the Sleep Heart Health StudySinziana Seicean
Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA
Diabetes Care 31:1001-6. 2008..To characterize the association between sleep-disordered breathing (SDB) and impaired fasting glucose (IFG), impaired glucose tolerance (IGT), combined IFG and IGT, and occult diabetes in individuals of different body habitus... - Long sleep duration: a risk to health or a marker of risk?Katherine A Stamatakis
Sleep Med Rev 11:337-9. 2007 - Improvement of metabolic function in sleep apnea: the power of positive pressureNaresh M Punjabi
Am J Respir Crit Care Med 169:139-40. 2004 - Sleep: a nourisher in life's feast?Alison M Laffan
Sleep Med Rev 12:253-5. 2008 - Relation of sleep-disordered breathing to carotid plaque and intima-media thicknessKeattiyoat Wattanakit
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Suite 300, 1300 South 2nd Street, Minneapolis, MN 55454, United States
Atherosclerosis 197:125-31. 2008..Sleep-disordered breathing (SDB) is associated with clinical cardiovascular disease (CVD), but its relation to subclinical atherosclerosis remains to be determined...
Research Grants
- EARLY IDENTIFICATION AND TREATMENT OF SLEEP APNEANaresh Punjabi; Fiscal Year: 2003Dr. Naresh Punjabi is a promising young investigator who has made a substantial commitment to an academic career in clinical research...
- Sleep Apnea and Longitudinal Changes in Glycemia and Inflammation in Older MenNaresh Punjabi; Fiscal Year: 2010....
- Mechanisms of Altered Glucose Metabolism in Sleep-Disordered BreathingNaresh Punjabi; Fiscal Year: 2010..We will also investigate whether treatment of sleep disordered breathing with continuous positive airway pressure improves metabolic function. ..
- Longtitudinal Changes in Sleep Structure: Implications for Health OutcomesNaresh Punjabi; Fiscal Year: 2009....
- Sleep Apnea and Longitudinal Changes in Glycemia and Inflammation in Older MenNaresh Punjabi; Fiscal Year: 2009....
- Longtitudinal Changes in Sleep Structure: Implications for Health OutcomesNaresh Punjabi; Fiscal Year: 2007....
- THE SLEEP HEART HEALTH STUDYNaresh Punjabi; Fiscal Year: 2007..Accomplishing these goals will provide important information concerning the public health impact of SDB. ..
- Effects of aging on sleep architectureNaresh Punjabi; Fiscal Year: 2006....
- The Effects of Sleep Apnea on Metabolic FunctionNaresh Punjabi; Fiscal Year: 2006..abstract_text> ..
- Longtitudinal Changes in Sleep Structure: Implications for Health OutcomesNaresh Punjabi; Fiscal Year: 2010....