Milo A Puhan

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. ncbi Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index
    Milo A Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet 374:704-11. 2009
  2. ncbi Support of personalized medicine through risk-stratified treatment recommendations - an environmental scan of clinical practice guidelines
    Tsung Yu
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    BMC Med 11:7. 2013
  3. ncbi A framework for organizing and selecting quantitative approaches for benefit-harm assessment
    Milo A Puhan
    Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Room E6153, Baltimore, MD 21205, USA
    BMC Med Res Methodol 12:173. 2012
  4. ncbi [Pulmonary rehabilitation - a modern and patient-centred treatment approach in COPD]
    Milo Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Praxis (Bern 1994) 102:99-106. 2013
  5. ncbi Early versus late pulmonary rehabilitation in chronic obstructive pulmonary disease patients with acute exacerbations: a randomized trial
    Milo A Puhan
    Horten Center for Patient oriented Research and Knowledge Transfer, University of Zurich, Zurich, Switzerland
    Respiration 83:499-506. 2012
  6. ncbi Perception of surgical complications among patients, nurses and physicians: a prospective cross-sectional survey
    Ksenija Slankamenac
    Department of Surgery, University Hospital Zurich, Switzerland
    Patient Saf Surg 5:30. 2011
  7. ncbi Patient-reported physical activity questionnaires: a systematic review of content and format
    Kate Williams
    Patient Reported Outcomes Centre of Excellence, Global Market Access, Primary Care Business Unit, Pfizer Ltd, Walton Oaks, Surrey, UK
    Health Qual Life Outcomes 10:28. 2012
  8. ncbi A comprehensive systematic review of the development process of 104 patient-reported outcomes (PROs) for physical activity in chronically ill and elderly people
    Anja Frei
    Horten Centre for Patient Oriented Research, University Hospital of Zurich, Switzerland
    Health Qual Life Outcomes 9:116. 2011
  9. ncbi Discussing study limitations in reports of biomedical studies- the need for more transparency
    Milo A Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Mail room E6153, Baltimore, MD 21205, USA
    Health Qual Life Outcomes 10:23. 2012
  10. ncbi Self-efficacy instruments for patients with chronic diseases suffer from methodological limitations--a systematic review
    Anja Frei
    Department of General Practice and Health Services Research, University Hospital of Zurich, Switzerland
    Health Qual Life Outcomes 7:86. 2009

Detail Information

Publications44

  1. ncbi Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index
    Milo A Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet 374:704-11. 2009
    ..We assessed the calibration of the BODE index, updated it to improve its calibration, and developed and validated a simplified index for use in primary-care settings...
  2. ncbi Support of personalized medicine through risk-stratified treatment recommendations - an environmental scan of clinical practice guidelines
    Tsung Yu
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    BMC Med 11:7. 2013
    ..abstract:..
  3. ncbi A framework for organizing and selecting quantitative approaches for benefit-harm assessment
    Milo A Puhan
    Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Room E6153, Baltimore, MD 21205, USA
    BMC Med Res Methodol 12:173. 2012
    ..Our aim was to review existing quantitative approaches for benefit-harm assessment and to develop an organizing framework that clarifies differences and aids selection of quantitative approaches for a particular benefit-harm assessment...
  4. ncbi [Pulmonary rehabilitation - a modern and patient-centred treatment approach in COPD]
    Milo Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Praxis (Bern 1994) 102:99-106. 2013
    ..This raises hopes that effective treatments could,through an increase in physical activity,reduce the risk for hospital admissions and early death in COPD patients...
  5. ncbi Early versus late pulmonary rehabilitation in chronic obstructive pulmonary disease patients with acute exacerbations: a randomized trial
    Milo A Puhan
    Horten Center for Patient oriented Research and Knowledge Transfer, University of Zurich, Zurich, Switzerland
    Respiration 83:499-506. 2012
    ..There are no trials comparing the different time points of referral for pulmonary rehabilitation...
  6. ncbi Perception of surgical complications among patients, nurses and physicians: a prospective cross-sectional survey
    Ksenija Slankamenac
    Department of Surgery, University Hospital Zurich, Switzerland
    Patient Saf Surg 5:30. 2011
    ..abstract:..
  7. ncbi Patient-reported physical activity questionnaires: a systematic review of content and format
    Kate Williams
    Patient Reported Outcomes Centre of Excellence, Global Market Access, Primary Care Business Unit, Pfizer Ltd, Walton Oaks, Surrey, UK
    Health Qual Life Outcomes 10:28. 2012
    ..This systematic review evaluates the content and format of patient-reported outcome (PRO) questionnaires that measure physical activity in elderly and chronically ill populations...
  8. ncbi A comprehensive systematic review of the development process of 104 patient-reported outcomes (PROs) for physical activity in chronically ill and elderly people
    Anja Frei
    Horten Centre for Patient Oriented Research, University Hospital of Zurich, Switzerland
    Health Qual Life Outcomes 9:116. 2011
    ..The aim of this systematic review was to assess the development process of patient-reported outcome (PRO) instruments including their initial validation to measure physical activity in chronically ill or elderly patient populations...
  9. ncbi Discussing study limitations in reports of biomedical studies- the need for more transparency
    Milo A Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Mail room E6153, Baltimore, MD 21205, USA
    Health Qual Life Outcomes 10:23. 2012
    ..Instead of perceiving acknowledgment of limitations negatively, authors, reviewers and editors should recognize the potential of a frank and unbiased discussion of study limitations that should not jeopardize acceptance of manuscripts...
  10. ncbi Self-efficacy instruments for patients with chronic diseases suffer from methodological limitations--a systematic review
    Anja Frei
    Department of General Practice and Health Services Research, University Hospital of Zurich, Switzerland
    Health Qual Life Outcomes 7:86. 2009
    ..Our aim was to systematically identify all existing self-efficacy scales for five major chronic diseases and to assess their development and validation process...
  11. ncbi ICE COLD ERIC--International collaborative effort on chronic obstructive lung disease: exacerbation risk index cohorts--study protocol for an international COPD cohort study
    Lara Siebeling
    Department of General Practice, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    BMC Pulm Med 9:15. 2009
    ..The objective of this study is to develop and validate a practical COPD disease risk index that predicts the clinical course of COPD in primary care patients with GOLD stages 2-4...
  12. ncbi The minimal important difference of exercise tests in severe COPD
    M A Puhan
    Dept of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Eur Respir J 37:784-90. 2011
    ..0-2.4 W), 3.2 W (95% CI 3.0-3.4 W), 3.2 W (95% CI 3.0-3.4 W) and 3.3 W (95% CI 3.0-3.5 W), while distribution-based estimates were 5.3 and 5.5 W. We suggest a MID of 26 ± 2 m for 6MWD and 4 ± 1 W for MCEC for patients with severe COPD...
  13. ncbi Excess mortality in patients with AIDS in the era of highly active antiretroviral therapy: temporal changes and risk factors
    Milo A Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Clin Infect Dis 51:947-56. 2010
    ..We assessed temporal changes in excess mortality and elucidated risk factors for excess mortality in patients with AIDS diagnosed in the era of highly active antiretroviral therapy (HAART)...
  14. ncbi Interviewer versus self-administered health-related quality of life questionnaires - does it matter?
    Milo A Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Health Qual Life Outcomes 9:30. 2011
    ....
  15. ncbi Inhaled drugs to reduce exacerbations in patients with chronic obstructive pulmonary disease: a network meta-analysis
    Milo A Puhan
    Horten Centre for patient oriented research and knowledge transfer, University of Zurich, Switzerland
    BMC Med 7:2. 2009
    ..Therefore we assessed, using a network meta-analytic technique, the relative effectiveness of the common inhaled drug regimes used to reduce exacerbations in patients with COPD...
  16. ncbi Protection of pharmacological postconditioning in liver surgery: results of a prospective randomized controlled trial
    Beatrice Beck-Schimmer
    Swiss HPB Hepato Pancreato Biliary Center, University Hospital Zurich, Zurich, Switzerland
    Ann Surg 256:837-44; discission 844-5. 2012
    ..To elucidate the possible organ-protective effect of pharmacological postconditioning in patients undergoing liver resection with inflow occlusion...
  17. ncbi Relative responsiveness of the Chronic Respiratory Questionnaire, St. Georges Respiratory Questionnaire and four other health-related quality of life instruments for patients with chronic lung disease
    Milo A Puhan
    Horten Centre, University of Zurich, Switzerland
    Respir Med 101:308-16. 2007
    ..The objective of this study was to compare the responsiveness of the Chronic Respiratory Questionnaire (CRQ), the St. Georges Respiratory Questionnaire (SGRQ) and four other HRQL instruments...
  18. ncbi The standard gamble showed better construct validity than the time trade-off
    Milo A Puhan
    Horten Centre, University of Zurich, Switzerland
    J Clin Epidemiol 60:1029-33. 2007
    ..There is little evidence for the relative cross-sectional validity of the standard gamble (SG) and time trade-off (TTO). We compared these preference-based instruments in patients with Irritable Bowel Syndrome (IBS)...
  19. ncbi Does pharmacological conditioning with the volatile anaesthetic sevoflurane offer protection in liver surgery?
    Ksenija Slankamenac
    Swiss HPB Hepato Pancreato Biliary Center, University Hospital of Zurich, Zurich, Switzerland
    HPB (Oxford) 14:854-62. 2012
    ..Whether the continuous application of volatile anaesthetics (pharmacological conditioning) also protects against I/R injury is unknown...
  20. ncbi Value of supplemental interventions to enhance the effectiveness of physical exercise during respiratory rehabilitation in COPD patients. A systematic review
    Milo A Puhan
    University of Zurich, Horten Centre, Switzerland
    Respir Res 5:25. 2004
    ..The aim of this research was to assess randomised controlled trials (RCTs) testing the additional benefit of supplemental interventions during respiratory rehabilitation in COPD patients...
  21. ncbi Prediction of first coronary events with the Framingham score: a systematic review
    Klaus Eichler
    Horten Centre for Patient Oriented Research, University Hospital of Zurich, Postfach Nord, Zurich, Switzerland
    Am Heart J 153:722-31, 731.e1-8. 2007
    ..Uncertainty exists about the performance of the Framingham risk score when applied in different populations...
  22. ncbi Respiratory rehabilitation after acute exacerbation of COPD may reduce risk for readmission and mortality -- a systematic review
    Milo A Puhan
    Horten Centre, University of Zurich, Switzerland
    Respir Res 6:54. 2005
    ..To study whether respiratory rehabilitation after acute exacerbation improves prognosis and health status compared to usual care, we quantified its effects using meta-analyses...
  23. ncbi Combining scores from different patient reported outcome measures in meta-analyses: when is it justified?
    Milo A Puhan
    Horten Centre, University of Zurich, Switzerland
    Health Qual Life Outcomes 4:94. 2006
    ....
  24. ncbi Interval versus continuous high-intensity exercise in chronic obstructive pulmonary disease: a randomized trial
    Milo A Puhan
    University of Zurich, Zurich, Switzerland
    Ann Intern Med 145:816-25. 2006
    ....
  25. ncbi Exacerbations of chronic obstructive pulmonary disease: when are antibiotics indicated? A systematic review
    Milo A Puhan
    Horten Centre, University Hospital of Zurich, Postfach Nord, Zurich, Switzerland
    Respir Res 8:30. 2007
    ..The aim of this systematic review was to analyse randomised controlled trials investigating the clinical benefit of antibiotics for COPD exacerbations...
  26. ncbi Dealing with heterogeneous populations in randomized wound trials: challenges and potential solutions
    Daniela Vollenweider
    Division of General Internal Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Wound Repair Regen 20:466-72. 2012
    ..Collaborative multicenter trials would overcome many of the limitations and provide statistical power to detect important treatment effects both overall and in subgroups...
  27. ncbi Self-administration and standardisation of the chronic respiratory questionnaire: a randomised trial in three German-speaking countries
    Milo A Puhan
    Horten Centre, University of Zurich, Postfach Nord, CH 8091 Zurich, Switzerland
    Respir Med 98:342-50. 2004
    ..Taken these results into consideration, researchers in COPD, in particular those in German-language countries can utilise any one of four CRQ formats that have proved both valid and responsive...
  28. ncbi Recruitment barriers in a randomized controlled trial from the physicians' perspective: a postal survey
    Anne Spaar
    Horten Centre for patient oriented research and knowledge transfer, University of Zurich, Switzerland
    BMC Med Res Methodol 9:14. 2009
    ..Therefore, our aim was to conduct a postal survey among recruiting physicians of a multi-center trial to weigh barriers according to their impact on recruitment...
  29. ncbi Where is the supporting evidence for treating mild to moderate chronic obstructive pulmonary disease exacerbations with antibiotics? A systematic review
    Milo A Puhan
    Horten Centre for patient oriented research and knowledge transfer, University of Zurich, Switzerland
    BMC Med 6:28. 2008
    ..Our aim was to study the evolvement of evidence from placebo-controlled and head-to-head trials on the effects of antibiotics for the treatment of mild to moderate exacerbations of chronic obstructive pulmonary disease...
  30. ncbi More medical journals should inform their contributors about three key principles of graph construction
    Milo A Puhan
    Horten Centre, University of Zurich, 8091 Zurich, Switzerland
    J Clin Epidemiol 59:1017-22. 2006
    ..To identify key principles of graph construction and to review guidance on graph construction provided by medical journals...
  31. ncbi Network meta-analysis-highly attractive but more methodological research is needed
    Tianjing Li
    Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21212, USA
    BMC Med 9:79. 2011
    ..Since this commentary reflects the discussion at that meeting, it is not intended to provide an overview of the field...
  32. ncbi High prevalence of potential biases threatens the interpretation of trials in patients with chronic disease
    Daniela Vollenweider
    Division of General Internal Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
    BMC Med 9:73. 2011
    ..Our aim was to assess such aspects of trial design and analysis for four prevalent chronic diseases...
  33. ncbi A randomized trial of ways to describe test accuracy: the effect on physicians' post-test probability estimates
    Milo A Puhan
    University of Zurich, Zurich, Switzerland
    Ann Intern Med 143:184-9. 2005
    ..Some people believe that likelihood ratios provide diagnostic information that is more useful than sensitivity and specificity estimates...
  34. ncbi Antibiotics for exacerbations of chronic obstructive pulmonary disease
    Daniela J Vollenweider
    General Internal Medicine, John Hopkins University, Baltimore, MD
    Cochrane Database Syst Rev 12:CD010257. 2012
    ..Many patients with an exacerbation of chronic obstructive pulmonary disease (COPD) are treated with antibiotics. However, the value of antibiotics remains uncertain as systematic reviews and clinical trials have shown conflicting results...
  35. ncbi Evaluation of guideline recommendations on oral medications for type 2 diabetes mellitus: a systematic review
    Wendy L Bennett
    The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Ann Intern Med 156:27-36. 2012
    ..Clinical practice guidelines have an important role in guiding choices among the numerous medications available to treat type 2 diabetes mellitus, but little is known about their quality...
  36. ncbi A quarter century experience in liver trauma: a plea for early computed tomography and conservative management for all hemodynamically stable patients
    Henrik Petrowsky
    Department of Surgery, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland
    World J Surg 36:247-54. 2012
    ..The objective of the present study was to investigate the impact of change in liver trauma management on outcome...
  37. ncbi Do citizens have minimum medical knowledge? A survey
    Lucas M Bachmann
    Horten Centre for Patient Oriented Research, University of Zurich, Postfach Nord, Zurich, Switzerland
    BMC Med 5:14. 2007
    ..We tested to what degree Swiss adult citizens satisfy this criterion for MMK and whether people with medical experience have acquired better knowledge than those without...
  38. ncbi The standard gamble demonstrated lower reliability than the feeling thermometer
    Milo A Puhan
    Horten Center, University of Zurich, Zurich, Switzerland
    J Clin Epidemiol 58:458-65. 2005
    ..Investigators should use appropriate reliability statistics when addressing related issues...
  39. ncbi Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease
    Milo A Puhan
    Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 Wolfe Street, Mail room W5010, Baltimore, MD, USA, 21205
    Cochrane Database Syst Rev 10:CD005305. 2011
    ..However, in unstable COPD patients who have recently suffered an exacerbation, the effects of pulmonary rehabilitation are less established...
  40. ncbi The impact of complications on costs of major surgical procedures: a cost analysis of 1200 patients
    René Vonlanthen
    Department of Surgery, University Hospital Zurich, Zurich, Switzerland
    Ann Surg 254:907-13. 2011
    ..To assess the impact of postoperative complications on full in-hospital costs per case...
  41. ncbi Didgeridoo playing as alternative treatment for obstructive sleep apnoea syndrome: randomised controlled trial
    Milo A Puhan
    Horten Centre, University of Zurich, 8091 Zurich, Switzerland
    BMJ 332:266-70. 2006
    ..CONCLUSION: Regular didgeridoo playing is an effective treatment alternative well accepted by patients with moderate obstructive sleep apnoea syndrome. Trial registration ISRCTN: 31571714...
  42. ncbi Comparative effectiveness and safety of medications for type 2 diabetes: an update including new drugs and 2-drug combinations
    Wendy L Bennett
    The Johns Hopkins University School of Medicine and The Johns Hopkins Bloomberg School of Public Health, 2024 East Monument Street, Baltimore, MD 21205, USA
    Ann Intern Med 154:602-13. 2011
    ..Given the increase in medications for type 2 diabetes mellitus, clinicians and patients need information about their effectiveness and safety to make informed choices...
  43. ncbi Predicting the risk of perioperative mortality in patients undergoing pancreaticoduodenectomy: a novel scoring system
    Raghunandan Venkat
    Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Arch Surg 146:1277-84. 2011
    ..To develop and validate a risk score to predict the 30- and 90-day mortality after a pancreaticoduodenectomy or total pancreatectomy on the basis of preoperative risk factors in a high-volume program...
  44. ncbi The minimal important difference in the 6-minute walk test for patients with pulmonary arterial hypertension
    Stephen C Mathai
    Johns Hopkins University School of Medicine, Division of Pulmonary and Critical Care Medicine, 1830 E Monument Street, Room 516, Baltimore, MD 21205, USA
    Am J Respir Crit Care Med 186:428-33. 2012
    ....