Research Topics
| G D PearlsonSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Superior temporal gyrus and planum temporale in schizophrenia: a selective reviewG D Pearlson
Division of Pychiatric Neuro Imaging, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Prog Neuropsychopharmacol Biol Psychiatry 21:1203-29. 1997..This disturbance may be closely associated with the symptoms of formal thought disorder and of auditory hallucinations commonly seen in the disorder...
PET study of competition between intravenous cocaine and [11C]raclopride at dopamine receptors in human subjectsT E Schlaepfer
Department of Psychiatry, Johns Hopkins Medical Institutions, Baltimore, USA
Am J Psychiatry 154:1209-13. 1997..The authors' goal was to determine whether this mechanism is the same in humans because the development of putative pharmacological agents for treatment of cocaine dependence depends on this knowledge...
Dynamic programming generation of boundaries of local coordinatized submanifolds in the neocortex: application to the planum temporaleJ T Ratnanather
Center for Imaging Science, The Johns Hopkins University, Baltimore, MD 21218 2686, USA
Neuroimage 20:359-77. 2003..96 for the left PT and 0.94 for the right PT, thus demonstrating the robustness of dynamic programming in defining a coordinate system on the PT. It provides a method with potential significance in the study of neuropsychiatric disorders...
Independent component analysis of fMRI data in the complex domainV D Calhoun
Division of Psychiatric Neuro Imaging, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
Magn Reson Med 48:180-92. 2002..5. Additionally, preliminary results from the complex models reveal a phase modulation similar to the magnitude time-course in some voxels, and oppositely modulated in other voxels...
fMRI activation in a visual-perception task: network of areas detected using the general linear model and independent components analysisV D Calhoun
Division of Psychiatry Neuro-Imaging, Johns Hopkins University, Baltimore, Maryland 21205, USA
Neuroimage 14:1080-8. 2001..Additionally, results illustrate functional connectivity between frontal eye fields and prefrontal and parietal regions...
A method for making group inferences from functional MRI data using independent component analysisV D Calhoun
Division of Psychiatric Neuro Imaging, Johns Hopkins University, Baltimore, Maryland, USA
Hum Brain Mapp 14:140-51. 2001....
Spatial and temporal independent component analysis of functional MRI data containing a pair of task-related waveformsV D Calhoun
Division of Psychiatric Neuro Imaging, Johns Hopkins University, Baltimore, Maryland, USA
Hum Brain Mapp 13:43-53. 2001....
Measurement of the planum temporale (PT) on magnetic resonance imaging scans: temporal PT alone and with parietal extensionN A Honeycutt
Division of Psychiatric Neuroimaging, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Meyer 3 166, 600 North Wolfe Street, Baltimore, MD 21287 7362, USA
Psychiatry Res 98:103-16. 2000..We review some of these studies and discuss methodological differences between them. Additionally, we propose a method that has proved to be highly reliable for the measurement of both temporal PT and its parietal extension (PT+)...
Site of opioid action in the human brain: mu and kappa agonists' subjective and cerebral blood flow effectsT E Schlaepfer
Department of Psychiatry, University Hospital, Bern, Switzerland
Am J Psychiatry 155:470-3. 1998....
Mesial temporal lobe measurements on magnetic resonance imaging scansN A Honeycutt
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287 7362, USA
Psychiatry Res 83:85-94. 1998....
Cerebral blood flow in obsessive-compulsive patients with major depression: effect of treatment with sertraline or desipramine on treatment responders and non-respondersR Hoehn-Saric
Department of Psychiatry, Johns Hopkins School of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
Psychiatry Res 108:89-100. 2001..Thus, higher prefrontal and subcortical activity was associated with better response to drug treatment. In addition, clinical change, but not the administration of medication as such, was associated with a decrease of prefrontal rCBF...
Elucidating the contributions of processing speed, executive ability, and frontal lobe volume to normal age-related differences in fluid intelligenceD Schretlen
Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Int Neuropsychol Soc 6:52-61. 2000..These findings suggest that both the processing speed and frontal-executive theory of cognitive aging are partially correct and complement one another...
Determinants of Benton Facial Recognition Test performance in normal adultsD J Schretlen
Department of Psychiatry and Behavior Sciences, Johns Hopkins University School of Medicine, Maryland, USA
Neuropsychology 15:405-10. 2001..VBR and processing speed alone accounted for nearly 34% of the variance. These findings suggest that both normal atrophic brain changes and decreases in processing speed contribute to individual differences in facial discrimination...
Diffusion tensor imaging and axonal tracking in the human brainstemB Stieltjes
Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
Neuroimage 14:723-35. 2001..The results reveal that each tract has a unique spatial signature in terms of water relaxation and diffusion anisotropy...
Neuroimaging studies in Rett syndromeS Naidu
The Kennedy Krieger Institute and the Johns Hopkins University, Baltimore, MD 21205, USA
Brain Dev 23:S62-71. 2001..The resulting neuroexcitotoxic injury to the developing brain contributes to the seizures, behavioral disturbance and respiratory irregularities commonly seen in phases 1 and 2 of this disorder...
Structural and functional brain changes in bipolar disorder: a selective reviewG D Pearlson
Psychiatry Neuroimaging, Johns Hopkins University, Baltimore, MD 21287, USA
Schizophr Res 39:133-40; discussion 162. 1999..We outline some of the strategies used to pursue answers to these questions and review conclusions to date...
Latency (in)sensitive ICA. Group independent component analysis of fMRI data in the temporal frequency domainV D Calhoun
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
Neuroimage 20:1661-9. 2003..The resulting time courses, the component maps, and the latency maps may prove useful as an addition to the collection of methods for fMRI data analysis...
Method for multimodal analysis of independent source differences in schizophrenia: combining gray matter structural and auditory oddball functional dataV D Calhoun
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
Hum Brain Mapp 27:47-62. 2006..controls, suggesting that more gray matter may be related to less functional connectivity in the auditory oddball fMRI task...
fMRI analysis with the general linear model: removal of latency-induced amplitude bias by incorporation of hemodynamic derivative termsV D Calhoun
Olin Neuropsychiatry Research Center, Institute of Living, 200 Retreat Avenue, Hartford, CT 06106, USA
Neuroimage 22:252-7. 2004..The proposed test is applied in a random-effects analysis of 100 subjects. It reveals increased amplitudes in areas consistent with the task, with the largest increases in regions with greater hemodynamic delays...
Neuronal chronometry of target detection: fusion of hemodynamic and event-related potential dataV D Calhoun
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
Neuroimage 30:544-53. 2006..We show that fusing imaging modalities with different advantages can provide new information about the brain...
A method for multi-group inter-participant correlation: abnormal synchrony in patients with schizophrenia during auditory target detectionD Kim
The MIND Research Network, Albuquerque, NM 87131, USA
Neuroimage 39:1129-41. 2008..This approach may also be sensitive to underlying, but unpredictable, changes in inter-participant BOLD synchrony between patients and controls...
