Ido Paz-Priel

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Thromboembolic events in children and young adults with pediatric sarcoma
    Ido Paz-Priel
    Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA
    J Clin Oncol 25:1519-24. 2007
  2. ncbi Cyclophosphamide for rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation syndrome
    Ido Paz-Priel
    Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD 21231, USA
    J Pediatr 158:337-9. 2011
  3. ncbi C/EBPα and C/EBPα oncoproteins regulate nfkb1 and displace histone deacetylases from NF-κB p50 homodimers to induce NF-κB target genes
    Ido Paz-Priel
    Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD, USA
    Blood 117:4085-94. 2011
  4. ncbi C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment
    Christine Yeamans
    Division of Pediatric Oncology, Johns Hopkins University, 1650 Orleans Street, Baltimore, MD 21231, USA
    Blood 110:3136-42. 2007
  5. ncbi C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction
    Julia E Dooher
    Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD 21231, USA
    Mol Cancer Res 9:1395-405. 2011
  6. ncbi C/EBPα dysregulation in AML and ALL
    Ido Paz-Priel
    Division of Pediatric Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Crit Rev Oncog 16:93-102. 2011
  7. ncbi NF-kappa B p50 regulates C/EBP alpha expression and inflammatory cytokine-induced neutrophil production
    Dehua Wang
    Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD 21231, USA
    J Immunol 182:5757-62. 2009

Collaborators

  • Alan D Friedman
  • Dehua Wang
  • Julia E Dooher
  • Christine Yeamans
  • Albert S Baldwin
  • Simone Houng
  • Daniel G Tenen
  • Bruce E Torbett

Detail Information

Publications7

  1. ncbi Thromboembolic events in children and young adults with pediatric sarcoma
    Ido Paz-Priel
    Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA
    J Clin Oncol 25:1519-24. 2007
    ..Adults with malignancy are at increased risk for venous thromboembolic events (TEs). However, data in children and young adults with cancer are limited...
  2. ncbi Cyclophosphamide for rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation syndrome
    Ido Paz-Priel
    Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD 21231, USA
    J Pediatr 158:337-9. 2011
    ..We report a patient who was treated successfully with high-dose cyclophosphamide immunoablation. This experience offers a novel therapeutic approach and an indirect insight into the underlying pathogenesis of this syndrome...
  3. ncbi C/EBPα and C/EBPα oncoproteins regulate nfkb1 and displace histone deacetylases from NF-κB p50 homodimers to induce NF-κB target genes
    Ido Paz-Priel
    Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD, USA
    Blood 117:4085-94. 2011
    ..These findings suggest that C/EBPs displace HDACs from p50 homodimers bound to antiapoptotic genes, contributing to NF-κB dysregulation in leukemia, and that the C/EBPα:p50 complex is a potential therapeutic target...
  4. ncbi C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment
    Christine Yeamans
    Division of Pediatric Oncology, Johns Hopkins University, 1650 Orleans Street, Baltimore, MD 21231, USA
    Blood 110:3136-42. 2007
    ..1(+/+), PU.1(+/-), or PU.1(+/kd) marrow myeloid progenitors but induces granulocyte lineage commitment in PU.1(kd/kd) cells lacking the PU.1 distal enhancer and does not induce either lineage in PU.1(-/-) cells...
  5. ncbi C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction
    Julia E Dooher
    Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD 21231, USA
    Mol Cancer Res 9:1395-405. 2011
    ....
  6. ncbi C/EBPα dysregulation in AML and ALL
    Ido Paz-Priel
    Division of Pediatric Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Crit Rev Oncog 16:93-102. 2011
    ..This review summarizes the normal hematopoietic developmental pathways regulated by C/EBPα and discusses the molecular pathways involved in mutated CEBPA AML and ALL...
  7. ncbi NF-kappa B p50 regulates C/EBP alpha expression and inflammatory cytokine-induced neutrophil production
    Dehua Wang
    Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD 21231, USA
    J Immunol 182:5757-62. 2009
    ..Together, these data indicate that acute inflammation not only activates mature myeloid cells, but also stimulates neutrophil production via NF-kappaB p50 induction of C/EBPalpha transcription...