Arvind P Pathak

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc In vivo "MRI phenotyping" reveals changes in extracellular matrix transport and vascularization that mediate VEGF-driven increase in breast cancer metastasis
    Arvind P Pathak
    JHU ICMIC Program, Division of Cancer Imaging Research, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 8:e63146. 2013
  2. doi request reprint Circulating and imaging markers for angiogenesis
    Arvind P Pathak
    JHU ICMIC Program, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Angiogenesis 11:321-35. 2008
  3. pmc Three-dimensional imaging of the mouse neurovasculature with magnetic resonance microscopy
    Arvind P Pathak
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 6:e22643. 2011
  4. doi request reprint Magnetic resonance susceptibility based perfusion imaging of tumors using iron oxide nanoparticles
    Arvind P Pathak
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University In Vivo Cellular Molecular Imaging Center, Baltimore, MD, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:84-97. 2009
  5. pmc Noninvasive multiparametric imaging of metastasis-permissive microenvironments in a human prostate cancer xenograft
    Marie France Penet
    The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University In Vivo Cellular And Molecular Imaging Center Program, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Cancer Res 69:8822-9. 2009
  6. ncbi request reprint Lymph node metastasis in breast cancer xenografts is associated with increased regions of extravascular drain, lymphatic vessel area, and invasive phenotype
    Arvind P Pathak
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Cancer Res 66:5151-8. 2006
  7. ncbi request reprint Characterizing vascular parameters in hypoxic regions: a combined magnetic resonance and optical imaging study of a human prostate cancer model
    Venu Raman
    The Johns Hopkins University, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Cancer Res 66:9929-36. 2006
  8. ncbi request reprint Molecular and functional imaging of cancer: advances in MRI and MRS
    Arvind P Pathak
    Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Methods Enzymol 386:3-60. 2004
  9. ncbi request reprint Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer
    Yelena Mironchik
    Department of Radiology, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21205, USA
    Cancer Res 65:10801-9. 2005
  10. ncbi request reprint Characterizing extravascular fluid transport of macromolecules in the tumor interstitium by magnetic resonance imaging
    Arvind P Pathak
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Cancer Res 65:1425-32. 2005

Collaborators

Detail Information

Publications28

  1. pmc In vivo "MRI phenotyping" reveals changes in extracellular matrix transport and vascularization that mediate VEGF-driven increase in breast cancer metastasis
    Arvind P Pathak
    JHU ICMIC Program, Division of Cancer Imaging Research, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 8:e63146. 2013
    ....
  2. doi request reprint Circulating and imaging markers for angiogenesis
    Arvind P Pathak
    JHU ICMIC Program, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Angiogenesis 11:321-35. 2008
    ..Such markers of angiogenesis are the subject of this review...
  3. pmc Three-dimensional imaging of the mouse neurovasculature with magnetic resonance microscopy
    Arvind P Pathak
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 6:e22643. 2011
    ....
  4. doi request reprint Magnetic resonance susceptibility based perfusion imaging of tumors using iron oxide nanoparticles
    Arvind P Pathak
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University In Vivo Cellular Molecular Imaging Center, Baltimore, MD, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:84-97. 2009
    ....
  5. pmc Noninvasive multiparametric imaging of metastasis-permissive microenvironments in a human prostate cancer xenograft
    Marie France Penet
    The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University In Vivo Cellular And Molecular Imaging Center Program, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Cancer Res 69:8822-9. 2009
    ..These results also provide the basis for clinically translatable noninvasive imaging markers for predicting metastatic risk in prostate cancer...
  6. ncbi request reprint Lymph node metastasis in breast cancer xenografts is associated with increased regions of extravascular drain, lymphatic vessel area, and invasive phenotype
    Arvind P Pathak
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Cancer Res 66:5151-8. 2006
    ..It is also possible that lymph node metastasis occurred via the cancer cell-bearing tumoral lymphatic vessels. The congestion of these tumoral lymphatics with cancer cells may have restricted the entry and transport of macromolecules...
  7. ncbi request reprint Characterizing vascular parameters in hypoxic regions: a combined magnetic resonance and optical imaging study of a human prostate cancer model
    Venu Raman
    The Johns Hopkins University, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Cancer Res 66:9929-36. 2006
    ..These observations are consistent with the possibility that regions of low vascular volumes are hypoxic, which induces increased expression of functionally active vascular endothelial growth factor, a potent vascular permeability factor...
  8. ncbi request reprint Molecular and functional imaging of cancer: advances in MRI and MRS
    Arvind P Pathak
    Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Methods Enzymol 386:3-60. 2004
  9. ncbi request reprint Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer
    Yelena Mironchik
    Department of Radiology, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21205, USA
    Cancer Res 65:10801-9. 2005
    ....
  10. ncbi request reprint Characterizing extravascular fluid transport of macromolecules in the tumor interstitium by magnetic resonance imaging
    Arvind P Pathak
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Cancer Res 65:1425-32. 2005
    ....
  11. doi request reprint Molecular imaging of metastatic potential
    Paul T Winnard
    Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore 21231, Maryland, USA
    J Nucl Med 49:96S-112S. 2008
    ..Below are examples of uses of molecular imaging of metastases as well as of metastatic potential, the former being a far more developed area of clinical inquiry...
  12. ncbi request reprint Magnetic resonance imaging and spectroscopy of transgenic models of cancer
    Venu Raman
    JHU ICMIC Program, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    NMR Biomed 20:186-99. 2007
    ....
  13. pmc Molecular and functional MRI of the tumor microenvironment
    Marie France Penet
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Nucl Med 49:687-90. 2008
  14. pmc Hypoxic tumor environments exhibit disrupted collagen I fibers and low macromolecular transport
    Samata M Kakkad
    JHU ICMIC Program, Division of Cancer Imaging Research, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America Universität Bremen, Fachbereich 2, Bremen, Germany
    PLoS ONE 8:e81869. 2013
    ..High Col1 fiber density observed around hypoxic regions may facilitate the escape of aggressive cancer cells from hypoxic regions. ..
  15. ncbi request reprint Molecular-functional imaging of cancer: to image and imagine
    Kristine Glunde
    JHU ICMIC Program, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Trends Mol Med 13:287-97. 2007
    ....
  16. doi request reprint In vivo laser speckle imaging reveals microvascular remodeling and hemodynamic changes during wound healing angiogenesis
    Abhishek Rege
    Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Angiogenesis 15:87-98. 2012
    ....
  17. pmc Applications of molecular MRI and optical imaging in cancer
    Marie France Penet
    JHU ICMIC Program, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Future Med Chem 2:975-88. 2010
    ..Here we have selected examples of MRI and optical imaging, to demonstrate how integrating imaging with novel probes can facilitate the successful treatment of this multifaceted disease...
  18. ncbi request reprint Magnetic resonance imaging of tumor physiology
    Arvind P Pathak
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Med 124:279-97. 2006
    ..This is followed by a description of revolutionary developments in the molecular imaging of tumors with MRI and complementary modalities...
  19. ncbi request reprint Visualizing function in the tumor-associated lymphatic system
    Arvind P Pathak
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Lymphat Res Biol 2:165-72. 2004
    ..This article reviews imaging and other techniques that allow the assessment of lymphatic function, particularly in the tumor microenvironment, and proposes novel solutions for probing the same in vivo...
  20. doi request reprint MR molecular imaging of tumor vasculature and vascular targets
    Arvind P Pathak
    JHU ICMIC Program, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Adv Genet 69:1-30. 2010
    ..In this review, we have focused on developments in the characterization of tumor vasculature with functional and molecular MRI...
  21. pmc A novel technique for modeling susceptibility-based contrast mechanisms for arbitrary microvascular geometries: the finite perturber method
    Arvind P Pathak
    JHU ICMIC Program, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neuroimage 40:1130-43. 2008
    ....
  22. doi request reprint Microdialysis measurement of intratumoral temozolomide concentration after cediranib, a pan-VEGF receptor tyrosine kinase inhibitor, in a U87 glioma model
    Rachel Grossman
    Department of Neurosurgery, Johns Hopkins University School of Medicine Baltimore, Baltimore, MD 21231, USA
    Cancer Chemother Pharmacol 72:93-100. 2013
    ..This study examines the intratumoral concentration of temozolomide (TMZ) in the presence and absence of the pan-VEGF receptor tyrosine kinase inhibitor, cediranib...
  23. pmc Multiscale imaging and computational modeling of blood flow in the tumor vasculature
    Eugene Kim
    Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Ann Biomed Eng 40:2425-41. 2012
    ....
  24. pmc Vascular phenotyping of brain tumors using magnetic resonance microscopy (μMRI)
    Eugene Kim
    The Whitaker Biomedical Engineering Institute at Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA
    J Cereb Blood Flow Metab 31:1623-36. 2011
    ....
  25. pmc Extracellular acidification alters lysosomal trafficking in human breast cancer cells
    Kristine Glunde
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neoplasia 5:533-45. 2003
    ..Filopodia formations, which were observed more frequently in highly metastatic breast cancer cells maintained at acidic pH(e), may also contribute to invasion...
  26. ncbi request reprint Novel system for determining contrast agent concentration in mouse blood in vivo
    Arvind P Pathak
    Department of Radiology, MR Oncology Section, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 51:612-5. 2004
    ....
  27. pmc Multiexposure laser speckle contrast imaging of the angiogenic microenvironment
    Abhishek Rege
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, Maryland 21205, USA
    J Biomed Opt 16:056006. 2011
    ..We demonstrate this utility of meLSCI by sequentially monitoring, over days, the microvascular changes that accompany wound healing in a mouse ear model...
  28. pmc Lymphatic injury and regeneration in cardiac allografts
    Thing Rinda Soong
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Transplantation 89:500-8. 2010
    ..Severed donor heart lymphatics are not anastomosed to recipient lymphatics in cardiac transplantation. We evaluated the effects of cellular infiltrates of T cells and macrophages on the morphology of lymphatics in heart grafts...