Research Topics
Species | Arvind P PathakSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Magnetic resonance susceptibility based perfusion imaging of tumors using iron oxide nanoparticlesArvind P Pathak
Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University In Vivo Cellular Molecular Imaging Center, Baltimore, MD, USA
Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:84-97. 2009....
Circulating and imaging markers for angiogenesisArvind P Pathak
JHU ICMIC Program, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Angiogenesis 11:321-35. 2008..Such markers of angiogenesis are the subject of this review...
Three-dimensional imaging of the mouse neurovasculature with magnetic resonance microscopyArvind P Pathak
Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
PLoS ONE 6:e22643. 2011....
Noninvasive multiparametric imaging of metastasis-permissive microenvironments in a human prostate cancer xenograftMarie France Penet
The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University In Vivo Cellular And Molecular Imaging Center Program, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Cancer Res 69:8822-9. 2009..These results also provide the basis for clinically translatable noninvasive imaging markers for predicting metastatic risk in prostate cancer...
Lymph node metastasis in breast cancer xenografts is associated with increased regions of extravascular drain, lymphatic vessel area, and invasive phenotypeArvind P Pathak
Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Cancer Res 66:5151-8. 2006..It is also possible that lymph node metastasis occurred via the cancer cell-bearing tumoral lymphatic vessels. The congestion of these tumoral lymphatics with cancer cells may have restricted the entry and transport of macromolecules...
Characterizing vascular parameters in hypoxic regions: a combined magnetic resonance and optical imaging study of a human prostate cancer modelVenu Raman
The Johns Hopkins University, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Cancer Res 66:9929-36. 2006..These observations are consistent with the possibility that regions of low vascular volumes are hypoxic, which induces increased expression of functionally active vascular endothelial growth factor, a potent vascular permeability factor...
Molecular and functional MRI of the tumor microenvironmentMarie-France Penet
Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Nucl Med 49:687-90. 2008
Molecular imaging of metastatic potentialPaul T Winnard
Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore 21231, Maryland, USA
J Nucl Med 49:96S-112S. 2008..Below are examples of uses of molecular imaging of metastases as well as of metastatic potential, the former being a far more developed area of clinical inquiry...
Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancerYelena Mironchik
Department of Radiology, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21205, USA
Cancer Res 65:10801-9. 2005....
In vivo laser speckle imaging reveals microvascular remodeling and hemodynamic changes during wound healing angiogenesisAbhishek Rege
Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Angiogenesis 15:87-98. 2012....
Applications of molecular MRI and optical imaging in cancerMarie France Penet
JHU ICMIC Program, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Future Med Chem 2:975-88. 2010..Here we have selected examples of MRI and optical imaging, to demonstrate how integrating imaging with novel probes can facilitate the successful treatment of this multifaceted disease...
Magnetic resonance imaging and spectroscopy of transgenic models of cancerVenu Raman
JHU ICMIC Program, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
NMR Biomed 20:186-99. 2007....
MR molecular imaging of tumor vasculature and vascular targetsArvind P Pathak
JHU ICMIC Program, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Adv Genet 69:1-30. 2010..In this review, we have focused on developments in the characterization of tumor vasculature with functional and molecular MRI...
Molecular-functional imaging of cancer: to image and imagineKristine Glunde
JHU ICMIC Program, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Trends Mol Med 13:287-97. 2007....
A novel technique for modeling susceptibility-based contrast mechanisms for arbitrary microvascular geometries: the finite perturber methodArvind P Pathak
JHU ICMIC Program, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Neuroimage 40:1130-43. 2008....
Visualizing function in the tumor-associated lymphatic systemArvind P Pathak
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Lymphat Res Biol 2:165-72. 2004..This article reviews imaging and other techniques that allow the assessment of lymphatic function, particularly in the tumor microenvironment, and proposes novel solutions for probing the same in vivo...
Multiscale imaging and computational modeling of blood flow in the tumor vasculatureEugene Kim
Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Ann Biomed Eng 40:2425-41. 2012....
Magnetic resonance imaging of tumor physiologyArvind P Pathak
Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Methods Mol Med 124:279-97. 2006..This is followed by a description of revolutionary developments in the molecular imaging of tumors with MRI and complementary modalities...
Vascular phenotyping of brain tumors using magnetic resonance microscopy (μMRI)Eugene Kim
The Whitaker Biomedical Engineering Institute at Johns Hopkins University School of Medicine, Baltimore 21205, Maryland, USA
J Cereb Blood Flow Metab 31:1623-36. 2011....
Characterizing extravascular fluid transport of macromolecules in the tumor interstitium by magnetic resonance imagingArvind P Pathak
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Cancer Res 65:1425-32. 2005....
Molecular and functional imaging of cancer: advances in MRI and MRSArvind P Pathak
Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Methods Enzymol 386:3-60. 2004
Multiexposure laser speckle contrast imaging of the angiogenic microenvironmentAbhishek Rege
Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, Maryland 21205, USA
J Biomed Opt 16:056006. 2011..We demonstrate this utility of meLSCI by sequentially monitoring, over days, the microvascular changes that accompany wound healing in a mouse ear model...
Lymphatic injury and regeneration in cardiac allograftsThing Rinda Soong
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Transplantation 89:500-8. 2010..Severed donor heart lymphatics are not anastomosed to recipient lymphatics in cardiac transplantation. We evaluated the effects of cellular infiltrates of T cells and macrophages on the morphology of lymphatics in heart grafts...
Novel system for determining contrast agent concentration in mouse blood in vivoArvind P Pathak
Department of Radiology, MR Oncology Section, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Magn Reson Med 51:612-5. 2004....
