Research TopicsGenomes and GenesSpecies | Michael ParsonsSummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
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Detail Information
Publications
Notch-responsive cells initiate the secondary transition in larval zebrafish pancreasMichael J Parsons
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Mech Dev 126:898-912. 2009..We also show that Notch-responsive cells persist in the adult pancreas and possess the classical characteristics of centroacinar cells, a cell type believed to be a multipotent progenitor cell in adult mammalian pancreas...
Gal4/UAS transgenic tools and their application to zebrafishMarnie E Halpern
Carnegie Institution for Science, Baltimore, Maryland, USA
Zebrafish 5:97-110. 2008..We describe some exciting new directions, in large part afforded by the Tol2 transposition system, that are generating valuable new Gal4/UAS reagents for zebrafish research...
Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductaseHarshan Pisharath
Department of Comparative Medicine, Johns Hopkins School of Medicine, 720 Rutland Avenue, Ross 771, Baltimore, MD 21205, USA
Mech Dev 124:218-29. 2007....
Transactivation from Gal4-VP16 transgenic insertions for tissue-specific cell labeling and ablation in zebrafishJon M Davison
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Dev Biol 304:811-24. 2007....
Nitroreductase-mediated cell ablation in transgenic zebrafish embryosHarshan Pisharath
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
Methods Mol Biol 546:133-43. 2009..Using the expression of NTR fused to a fluorescent protein, one can simultaneously make cells susceptible to prodrug treatment and visualize cell ablation as it occurs...
Research Grants
- Identifying the progenitors responsible for Beta Cell regeneration in zebrafishMichael Parsons; Fiscal Year: 2010..It is hoped that by understanding how progenitors differentiate into insulin producing cells in our model system will allow the development of better techniques to differentiate beta cells for therapeutic purposes in the future. ..
- Identifying the progenitors responsible for Beta Cell regeneration in zebrafishMichael Parsons; Fiscal Year: 2010..It is hoped that by understanding how progenitors differentiate into insulin producing cells in our model system will allow the development of better techniques to differentiate beta cells for therapeutic purposes in the future. ..
