Research Topics
Species | Nicole M ParrishSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Role of the clinical mycobacteriology laboratory in diagnosis and management of tuberculosis in low-prevalence settingsNicole M Parrish
Johns Hopkins Medical Institutions, Baltimore, Maryland, Baltimore, Maryland, USA
J Clin Microbiol 49:772-6. 2011..Finally, gamma interferon release assays are preferred to the tuberculin skin test for screening certain at-risk populations, and new CDC guidelines are available that assist clinicians in their use...
Activity of DSA against anaerobically adapted Mycobacterium bovis BCG in vitroNicole M Parrish
Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Tuberculosis (Edinb) 89:325-7. 2009..Conclusive identification of the DSA-specific target(s) will permit a better understanding of the unique mechanism of action of this class of compounds against both aerobically growing and anaerobically adapted bacilli in vitro...
Rapid, standardized method for determination of Mycobacterium tuberculosis drug susceptibility by use of mycolic acid analysisNicole Parrish
Department of Pathology, Division of Medical Microbiology, Johns Hopkins University, Baltimore, MD 21287, USA
J Clin Microbiol 45:3915-20. 2007..tuberculosis and offers the potential of providing susceptibility testing results within hours, rather than days or weeks, for clinical M. tuberculosis isolates...
Importance of improved TB diagnostics in addressing the extensively drug-resistant TB crisisNicole Parrish
The Johns Hopkins Medical Institutions, Johns Hopkins University, 600 North Wolfe Street, Meyer B1 193, Baltimore, MD 21287, USA
Future Microbiol 3:405-13. 2008..Such an approach is essential for the future of TB control and stemming the tide of MDR-TB and XDR-TB...
Differences in time to detection and recovery of Mycobacterium spp. between the MGIT 960 and the BacT/ALERT MB automated culture systemsNicole Parrish
The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Diagn Microbiol Infect Dis 63:342-5. 2009..The MGIT 960 demonstrated shorter time to detection (13.5 versus 25.2 days) and greater sensitivity (100% versus 66.6%) for recovery of the Mycobacterium tuberculosis complex than the BacT/ALERT MB system...
Effect of n-octanesulphonylacetamide (OSA) on ATP and protein expression in Mycobacterium bovis BCGNicole M Parrish
Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
J Antimicrob Chemother 54:722-9. 2004..These effects may hinder energy production, leading to interruption in the synthesis of large macromolecules including proteins and mycolic acids...
Cost-effectiveness analysis of the gen-probe amplified mycobacterium tuberculosis direct test as used routinely on smear-positive respiratory specimensDavid W Dowdy
Johns Hopkins Bloomberg School of Public Health Johns Hopkins Hospital Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
J Clin Microbiol 41:948-53. 2003....
Case of Mycobacterium marinum infection with unusual patterns of susceptibility to commonly used antibioticsNicole Parrish
Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Clin Microbiol 49:2056-8. 2011..Susceptibility testing is not routinely performed, and single-drug therapy is used for the treatment of most infections. Here, we report an infection caused by a drug-resistant M. marinum strain in an otherwise healthy patient...
Growth, Congo Red agar colony morphotypes and antibiotic susceptibility testing of Mycobacterium avium subspecies paratuberculosisNicole M Parrish
Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Clin Med Res 2:107-14. 2004..This study also emphasizes the need for the development of improved, standardized culture and susceptibility test methods for MAP...
Absence of mycobacterium avium subsp. paratuberculosis in Crohn's patientsNicole M Parrish
Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Inflamm Bowel Dis 15:558-65. 2009..In addition, each blood sample was analyzed for polymorphisms in the NOD2/CARD15 gene previously associated with CD...
Use of the "RAM" susceptibility testing method for rapid detection of clarithromycin resistance in the Mycobacterium avium complexVictor Flauta
Division of Medical Microbiology, Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA
Diagn Microbiol Infect Dis 67:47-51. 2010....
Evaluation of a rapid fluorescent staining method for detection of mycobacteria in clinical specimensCindy Hendry
The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
J Clin Microbiol 47:1206-8. 2009..These results suggest that the rapid stain may be more cost-effective and efficient for use in clinical laboratories...
Methods for reducing bacterial contamination in the BacT/Alert mycobacterial culture detection systemKim Dionne
Division of Medical Microbiology, Johns Hopkins University, Meyer B1-193, 600 N. Wolfe Street, Baltimore, MD 21287, USA
J Clin Microbiol 43:2523-5. 2005..0 ml, of mycobacterial antibiotic supplement were evaluated. Contamination rates were 14% and 6% for the standard and the doubled concentrations, respectively. This difference was statistically significant (P < 0.005)...
