PAUL ALAN NYQUIST
Affiliation: Johns Hopkins University
- Protein biomarkers in patients with subarachnoid hemorrhage, vasospasm, and delayed ischemic neurological deficitsPaul A Nyquist
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
Acta Neurochir Suppl 115:23-5. 2013..Future studies in larger sample populations are needed to evaluate these biomarkers further as representative of biosystems involved in vasospasm and DIND or as potential biomarkers predictive of risk associated with disease...
- Management of acute intracranial and intraventricular hemorrhagePaul Nyquist
Neurology Anesthesiology Critical Care Medicine Neurosurgery, Johns Hopkins School of Medicine, Baltimore Maryland, USA
Crit Care Med 38:946-53. 2010..The goal of this review is to familiarize clinicians with recent information pertaining to the acute care of intracranial hemorrhage and intraventricular hemorrhage...
- The use of intraventricular thrombolytics in intraventricular hemorrhagePaul Nyquist
Neurology and Anesthesia Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore Maryland, 21287 7840, USA
J Neurol Sci 261:84-8. 2007..Preliminary data suggests that it may be successful in patients with IVH in this setting. This trial is the accumulation of animal and human trials completed over the last 20 years...
- Thrombolytics in intraventricular hemorrhagePaul Nyquist
Division of Neurosciences Critical Care, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 8 138, Baltimore, MD 21287 7840, USA
Curr Neurol Neurosci Rep 7:522-8. 2007..A review of the use of thrombolytics for treatment of IVH related to other secondary causes is also provided...
- The -928 G/C and -362 G/C single-nucleotide polymorphisms in the promoter of MCP-1: Increased transcriptional activity and novel binding sitesPaul Nyquist
Division of Neurosciences Critical Care and Departments of Neurology, Anesthesiology Critical Care Medicine and Neurosurgery, Johns Hopkins University School of Medicine, Bethesda, MD, USA
Cerebrovasc Dis 29:242-7. 2010..We characterized the transcriptional activity of these two SNPs in vitro and identified transcription factors that bind to them...
- Neurologic injury and mechanical ventilationPaul Nyquist
Division of Neurosciences Critical Care, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Neurocrit Care 9:400-8. 2008..We will examine the consequences of ventilator management as they relate to parameters that affect ICP and brain oxygenation in patients who have neurologic injury...
- Single nucleotide polymorphisms in monocyte chemoattractant protein-1 and its receptor act synergistically to increase the risk of carotid atherosclerosisPaul A Nyquist
Department of Anesthesiology Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Cerebrovasc Dis 28:124-30. 2009....
- A change of position for neurogenic pulmonary edemaScott A Marshall
Department of Neurosciences Critical Care, The Johns Hopkins Hospital, Johns Hopkins University, Baltimore, MD, USA
Neurocrit Care 10:213-7. 2009..While the principles of management of this type of pulmonary edema are similar to the more common cardiogenic pulmonary edema, placing a patient in the prone position may be a helpful maneuver facilitating recovery...
- Impact of establishing a primary stroke center at a community hospital on the use of thrombolytic therapy: the NINDS Suburban Hospital Stroke Center experienceSusan Unipan Lattimore
Stroke Branch, National Institute of Neurological Disorders and Stroke, 10 Center Dr, MSC 1063, Building 10, Room B1D733, Bethesda, MD 20892 1063, USA
Stroke 34:e55-7. 2003..We evaluated the use of thrombolytic therapy before and after institution of a primary stroke center in a community hospital...
- ICH aspiration and thrombolysisNeeraj S Naval
Division of Neurosciences Critical Care, Departments of Neurology, Neurosurgery and Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
J Neurol Sci 261:80-3. 2007..Minimally invasive surgery (MIS) using stereotactic clot aspiration followed by clot lysis is gaining credibility as an alternative management strategy. We review the published data on this methodology in the treatment of ICH...
- Effect of hypertonic saline concentration on cerebral and visceral organ water in an uninjured rodent modelThomas J Toung
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Crit Care Med 36:256-61. 2008..We compared the effects of different tonicity of infused hypertonic saline on cerebral, lung, and small bowel water extraction over time under controlled conditions...
- Noninvasive imaging techniques in the diagnosis and management of aneurysmal subarachnoid hemorrhageScott A Marshall
Division of Neurosciences Critical Care, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
Neurosurg Clin N Am 21:305-23. 2010..The current evidence for the use of these newer modalities is described for the diagnosis of aSAH and the management of its sequelae including VS...