DALE MURRAY contact NEEDHAM

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. doi request reprint Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference
    Dale M Needham
    OACIS Group, Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Crit Care Med 40:502-9. 2012
  2. pmc The functional comorbidity index had high inter-rater reliability in patients with acute lung injury
    Eddy Fan
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    BMC Anesthesiol 12:21. 2012
  3. pmc One year outcomes in patients with acute lung injury randomised to initial trophic or full enteral feeding: prospective follow-up of EDEN randomised trial
    Dale M Needham
    Outcomes After Critical Illness and Surgery Group, Johns Hopkins University, Baltimore, MD 21205, USA
    BMJ 346:f1532. 2013
  4. pmc Lung protective mechanical ventilation and two year survival in patients with acute lung injury: prospective cohort study
    Dale M Needham
    Outcomes After Critical Illness and Surgery Group, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    BMJ 344:e2124. 2012
  5. pmc A knowledge translation collaborative to improve the use of therapeutic hypothermia in post-cardiac arrest patients: protocol for a stepped wedge randomized trial
    Katie N Dainty
    RESCU Research Program, Keenan Research Centre, Li Ka Shing Knowledge Institute, St, Michael s Hospital Toronto, Canada
    Implement Sci 6:4. 2011
  6. pmc Mortality in sepsis versus non-sepsis induced acute lung injury
    Jonathan E Sevransky
    Division of Pulmonary and Critical Care, Johns Hopkins University, 5501 Hopkins Bayview Circle Baltimore, MD 21224 USA
    Crit Care 13:R150. 2009
  7. pmc Bench-to-bedside review: mobilizing patients in the intensive care unit--from pathophysiology to clinical trials
    Alex D Truong
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Crit Care 13:216. 2009
  8. pmc ICU staffing and patient outcomes: more work remains
    David J Murphy
    Pulmonary and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    Crit Care 13:101. 2009
  9. doi request reprint Technology to enhance physical rehabilitation of critically ill patients
    Dale M Needham
    Division of Pulmonary and Critical Care Medicine, Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD, USA
    Crit Care Med 37:S436-41. 2009
  10. pmc Intensive care unit exposures for long-term outcomes research: development and description of exposures for 150 patients with acute lung injury
    Dale M Needham
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    J Crit Care 22:275-84. 2007

Detail Information

Publications70

  1. doi request reprint Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference
    Dale M Needham
    OACIS Group, Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Crit Care Med 40:502-9. 2012
    ..These intensive care survivors and their families frequently report a wide range of impairments in their health status which may last for months and years after hospital discharge...
  2. pmc The functional comorbidity index had high inter-rater reliability in patients with acute lung injury
    Eddy Fan
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    BMC Anesthesiol 12:21. 2012
    ..abstract:..
  3. pmc One year outcomes in patients with acute lung injury randomised to initial trophic or full enteral feeding: prospective follow-up of EDEN randomised trial
    Dale M Needham
    Outcomes After Critical Illness and Surgery Group, Johns Hopkins University, Baltimore, MD 21205, USA
    BMJ 346:f1532. 2013
    ..To evaluate the effect of initial low energy permissive underfeeding ("trophic feeding") versus full energy enteral feeding ("full feeding") on physical function and secondary outcomes in patients with acute lung injury...
  4. pmc Lung protective mechanical ventilation and two year survival in patients with acute lung injury: prospective cohort study
    Dale M Needham
    Outcomes After Critical Illness and Surgery Group, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    BMJ 344:e2124. 2012
    ..To evaluate the association of volume limited and pressure limited (lung protective) mechanical ventilation with two year survival in patients with acute lung injury...
  5. pmc A knowledge translation collaborative to improve the use of therapeutic hypothermia in post-cardiac arrest patients: protocol for a stepped wedge randomized trial
    Katie N Dainty
    RESCU Research Program, Keenan Research Centre, Li Ka Shing Knowledge Institute, St, Michael s Hospital Toronto, Canada
    Implement Sci 6:4. 2011
    ..Despite the strong evidence for its efficacy and the apparent simplicity of this intervention, recent surveys show that therapeutic hypothermia is delivered inconsistently, incompletely, and often with delay...
  6. pmc Mortality in sepsis versus non-sepsis induced acute lung injury
    Jonathan E Sevransky
    Division of Pulmonary and Critical Care, Johns Hopkins University, 5501 Hopkins Bayview Circle Baltimore, MD 21224 USA
    Crit Care 13:R150. 2009
    ..Sepsis-induced acute lung injury (ALI) has been reported to have a higher case fatality rate than other causes of ALI. However, differences in the severity of illness in septic vs. non-septic ALI patients might explain this finding...
  7. pmc Bench-to-bedside review: mobilizing patients in the intensive care unit--from pathophysiology to clinical trials
    Alex D Truong
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Crit Care 13:216. 2009
    ..Further research is required to determine whether early mobility in the ICU can improve patients' short-term and long-term outcomes...
  8. pmc ICU staffing and patient outcomes: more work remains
    David J Murphy
    Pulmonary and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    Crit Care 13:101. 2009
    ..Future studies should evaluate other potential mechanisms by which closed ICUs improve patient outcomes. An improved understanding of these mechanisms may yield new targets for improving the quality of medical care for all ICU patients...
  9. doi request reprint Technology to enhance physical rehabilitation of critically ill patients
    Dale M Needham
    Division of Pulmonary and Critical Care Medicine, Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD, USA
    Crit Care Med 37:S436-41. 2009
    ..The introduction of physical medicine and rehabilitation-related technology into the intensive care unit may help facilitate delivery of this therapy...
  10. pmc Intensive care unit exposures for long-term outcomes research: development and description of exposures for 150 patients with acute lung injury
    Dale M Needham
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    J Crit Care 22:275-84. 2007
    ..This report describes the development of a strategy for comprehensively measuring relevant exposures for long-term outcomes research, and presents empiric results from its implementation...
  11. ncbi request reprint Patient safety, quality of care, and knowledge translation in the intensive care unit
    Dale M Needham
    Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, 1830 East Monument Street, 5th Floor, Baltimore MD 21205, USA
    Respir Care 55:922-8. 2010
    ....
  12. doi request reprint Early physical medicine and rehabilitation for patients with acute respiratory failure: a quality improvement project
    Dale M Needham
    Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD, USA
    Arch Phys Med Rehabil 91:536-42. 2010
    ..To (1) reduce deep sedation and delirium to permit mobilization, (2) increase the frequency of rehabilitation consultations and treatments to improve patients' functional mobility, and (3) evaluate effects on length of stay...
  13. pmc Improving data quality control in quality improvement projects
    Dale M Needham
    Pulmonary and Critical Care, Johns Hopkins University, Baltimore, MD, USA
    Int J Qual Health Care 21:145-50. 2009
    ..Our objective was to provide a primer on basic data quality control methods appropriate for QI efforts...
  14. doi request reprint Mobilizing patients in the intensive care unit: improving neuromuscular weakness and physical function
    Dale M Needham
    Division of Pulmonary and Critical Care Medicine, and Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, Maryland 21205, USA
    JAMA 300:1685-90. 2008
    ..Emerging research in this field provides preliminary evidence supporting the safety, feasibility, and potential benefits of early mobilization in critical care medicine...
  15. pmc Are intensive care factors associated with depressive symptoms 6 months after acute lung injury?
    David W Dowdy
    School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Crit Care Med 37:1702-7. 2009
    ..To evaluate intensive care-related factors as predictors of depressive symptoms 6 months after acute lung injury (ALI)...
  16. ncbi request reprint A system factors analysis of airway events from the Intensive Care Unit Safety Reporting System (ICUSRS)
    Dale M Needham
    Pulmonary and Critical Care Medicine, and Dana Center for Preventive Ophthalmology Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 32:2227-33. 2004
    ..To evaluate the contributing and limiting factors for airway events reported in the Intensive Care Unit Safety Reporting System (ICUSRS) developed in partnership with the Society of Critical Care Medicine...
  17. pmc Study protocol: The Improving Care of Acute Lung Injury Patients (ICAP) study
    Dale M Needham
    Johns Hopkins University, 5th Floor, 1830 East Monument Street, Baltimore, MD 21205, USA
    Crit Care 10:R9. 2006
    ....
  18. pmc Intensive care unit hypoglycemia predicts depression during early recovery from acute lung injury
    David W Dowdy
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Crit Care Med 36:2726-33. 2008
    ..To evaluate the association between intensive care unit blood glucose levels and depression after acute lung injury...
  19. pmc Creating high reliability in health care organizations
    Peter J Pronovost
    Department of Anesthesiology and Critical Care Medicine, Surgery, and Health Policy and Management, The Johns Hopkins University, 1901 Thames Street, 2nd Floor, Baltimore, MD 21231, USA
    Health Serv Res 41:1599-617. 2006
    ..The objective of this paper was to present a comprehensive approach to help health care organizations reliably deliver effective interventions...
  20. doi request reprint Psychiatric morbidity in survivors of the acute respiratory distress syndrome: a systematic review
    Dimitry S Davydow
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Psychosom Med 70:512-9. 2008
    ....
  21. ncbi request reprint Quality of life in adult survivors of critical illness: a systematic review of the literature
    David W Dowdy
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Intensive Care Med 31:611-20. 2005
    ..To determine how the quality of life (QOL) of intensive care unit (ICU) survivors compares with the general population, changes over time, and is predicted by baseline characteristics...
  22. doi request reprint Human immunodeficiency virus infection and hospital mortality in acute lung injury patients
    Pedro A Mendez-Tellez
    Department of Anesthesiology and Critical Care Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Crit Care Med 38:1530-5. 2010
    ..To evaluate the impact of human immunodeficiency virus infection on hospital mortality in patients with acute lung injury and to evaluate predictors of mortality among acute lung injury patients with human immunodeficiency virus...
  23. ncbi request reprint Team care: beyond open and closed intensive care units
    Peter J Pronovost
    Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland 21231, USA
    Curr Opin Crit Care 12:604-8. 2006
    ..The purpose of this paper is to accelerate patient's exposure to the benefits of intensivists, and introduce team care in the intensive care unit...
  24. doi request reprint Translating evidence into practice: a model for large scale knowledge translation
    Peter J Pronovost
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Quality and Safety Research Group, 1909 Thames Street, Baltimore, MD 21231, USA
    BMJ 337:a1714. 2008
  25. doi request reprint The use of personal protective equipment for control of influenza among critical care clinicians: A survey study
    Elizabeth L Daugherty
    Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 37:1210-6. 2009
    ..Although effective PPE use may significantly reduce healthcare-associated influenza transmission, PPE adherence among ICU HCWs for preventing nosocomial influenza infection has not been evaluated...
  26. pmc Inter-rater reliability of manual muscle strength testing in ICU survivors and simulated patients
    Eddy Fan
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 East Monument Street, 5th Floor, Baltimore, MD 21205, USA
    Intensive Care Med 36:1038-43. 2010
    ..DESIGN, SUBJECTS, AND SETTING: The authors report on 19 trainees undergoing quality assurance within a multi-site prospective cohort study...
  27. doi request reprint A framework for diagnosing and classifying intensive care unit-acquired weakness
    Robert D Stevens
    Division of Neurosciences Critical Care, Department of Anesthesiology Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 37:S299-308. 2009
    ..We propose a simple framework for diagnosing and classifying neuromuscular disorders acquired in critical illness...
  28. pmc Pulmonary vs nonpulmonary sepsis and mortality in acute lung injury
    Jonathan E Sevransky
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Chest 134:534-8. 2008
    ..Acute lung injury (ALI) is a frequent complication of sepsis. It is unclear if a pulmonary vs nonpulmonary source of sepsis affects mortality in patients with sepsis-induced ALI...
  29. ncbi request reprint Barriers to low tidal volume ventilation in acute respiratory distress syndrome: survey development, validation, and results
    Cheryl R Dennison
    School of Nursing, Johns Hopkins University, Baltimore, MD, USA
    Crit Care Med 35:2747-54. 2007
    ..To evaluate perceived attitudes, knowledge, and behaviors regarding the use of low tidal volume ventilation in acute respiratory distress syndrome among physicians, nurses, and respiratory therapists in intensive care units...
  30. doi request reprint Monitoring and reducing central line-associated bloodstream infections: a national survey of state hospital associations
    David J Murphy
    Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Am J Med Qual 25:255-60. 2010
    ..A national collaborative to address CLABSIs may reduce these infections while building capacity to improve other aspects of health care quality...
  31. ncbi request reprint Improving the quality of quality improvement projects
    Sean M Berenholtz
    Johns Hopkins University School of Medicine, Department of Anesthesiology and Critical Care Medicine, Quality and Safety Research Group, Baltimore, USA
    Jt Comm J Qual Patient Saf 36:468-73. 2010
    ..Our patients deserve nothing less...
  32. ncbi request reprint Neuromuscular dysfunction acquired in critical illness: a systematic review
    Robert D Stevens
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 8 140, Baltimore, MD 21287, USA
    Intensive Care Med 33:1876-91. 2007
    ..To determine the prevalence, risk factors, and outcomes of critical illness neuromuscular abnormalities (CINMA)...
  33. doi request reprint Evaluation of two intensive care delirium screening tools for non-critically ill hospitalized patients
    Karin J Neufeld
    Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD 21287 5371, USA
    Psychosomatics 52:133-40. 2011
    ..While easy-to-use delirium screening tools exist for ventilated patients, their use in non-critically ill, hospitalized patients has not been validated...
  34. ncbi request reprint Studying outcomes of intensive care unit survivors: measuring exposures and outcomes
    Dale M Needham
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Intensive Care Med 31:1153-60. 2005
    ..There is little systematic guidance for measuring these outcomes and exposures within the ICU setting. As a result measurement methods are often variable and non-comparable across studies...
  35. ncbi request reprint Studying outcomes of intensive care unit survivors: the role of the cohort study
    David W Dowdy
    School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Intensive Care Med 31:914-21. 2005
    ..As research focuses on long-term patient outcomes and the "real world" effectiveness of intensive care unit (ICU) therapies, the cohort study is increasingly being used in critical care research...
  36. ncbi request reprint A system factors analysis of "line, tube, and drain" incidents in the intensive care unit
    Dale M Needham
    Department of Pulmonary and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 33:1701-7. 2005
    ..To analyze the system factors related to "line, tube, and drain" (LTD) incidents in the intensive care unit (ICU)...
  37. ncbi request reprint The efficacy of sirolimus- and paclitaxel-eluting stents: a meta-analysis of randomized controlled trials
    Michelle M Kittleson
    Department of Medicine, Division of Cardiology, Epidemiology and Clinical Research, John Hopkins Medical Institute, Baltimore, MD, USA
    Can J Cardiol 21:581-7. 2005
    ....
  38. ncbi request reprint Hospital volume and mortality for mechanical ventilation of medical and surgical patients: a population-based analysis using administrative data
    Dale M Needham
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Crit Care Med 34:2349-54. 2006
    ..Our objective is to determine whether hospital volume is associated with improved survival for medical or surgical patients receiving mechanical ventilation...
  39. doi request reprint How to use an article about quality improvement
    Eddy Fan
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins Medical Institutions, 1830 E Monument St, Fifth Floor, Baltimore, MD 21287, USA
    JAMA 304:2279-87. 2010
    ..Given the potential for widespread implementation of QI interventions, there is a need for robust study methods in QI research...
  40. pmc Hemodynamic goals in randomized clinical trials in patients with sepsis: a systematic review of the literature
    Jonathan E Sevransky
    Department of Pulmonary Critical Care Medicine, Johns Hopkins University, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Crit Care 11:R67. 2007
    ..Patients with sepsis suffer high morbidity and mortality. We sought to conduct a systematic review of the literature to evaluate the association between hemodynamic goals of therapy and patient outcomes...
  41. doi request reprint Long-term mortality and quality of life in sepsis: a systematic review
    Bradford D Winters
    Departments of Anesthesiology and Critical Care Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 38:1276-83. 2010
    ..Whether patients with sepsis have similar long-term mortality and quality-of-life effects is unclear...
  42. pmc Systematic review identifies number of strategies important for retaining study participants
    Karen A Robinson
    Division of Internal Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    J Clin Epidemiol 60:757-65. 2007
    ..We conducted a systematic review of studies with a primary focus on strategies to retain participants in health care research...
  43. ncbi request reprint A framework for health care organizations to develop and evaluate a safety scorecard
    Peter J Pronovost
    Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    JAMA 298:2063-5. 2007
  44. doi request reprint The impact of obesity on outcomes after critical illness: a meta-analysis
    Charles W Hogue
    Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Intensive Care Med 35:1152-70. 2009
    ..To assess whether obesity is associated with mortality or other adverse intensive care unit (ICU) and post-ICU outcomes...
  45. ncbi request reprint Intensive care unit physician staffing: financial modeling of the Leapfrog standard
    Peter J Pronovost
    Department of Anesthesiology and Critical Care, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 32:1247-53. 2004
    ....
  46. ncbi request reprint A systematic review of the Charlson comorbidity index using Canadian administrative databases: a perspective on risk adjustment in critical care research
    Dale M Needham
    Department of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    J Crit Care 20:12-9. 2005
    ..Future research should focus on updating the Charlson index for recent changes in the prognosis of comorbid diseases and introduction of International Statistical Classification of Diseases, 10th Revision coding of discharge abstracts...
  47. doi request reprint Review of a large clinical series: sedation and analgesia usage with airway pressure release and assist-control ventilation for acute lung injury
    Eddy Fan
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    J Intensive Care Med 23:376-83. 2008
    ..Our objective was to compare sedative and analgesic doses, agents, and sedation status in patients with airway pressure release ventilation (APRV) versus assist-control (AC) ventilation on the first day after acute lung injury diagnosis...
  48. ncbi request reprint Quality of life after acute respiratory distress syndrome: a meta-analysis
    David W Dowdy
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Intensive Care Med 32:1115-24. 2006
    ..To summarize long-term quality of life (QOL) and the degree of variation in QOL estimates across studies of acute respiratory distress (ARDS) survivors...
  49. doi request reprint Critical illness neuromyopathy and muscle weakness in patients in the intensive care unit
    Eddy Fan
    Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    AACN Adv Crit Care 20:243-53. 2009
    ..Future studies are needed to elucidate the multiple mechanisms by which immobility, CINM, and other aspects of critical illness lead to muscle loss and neuromuscular dysfunction...
  50. doi request reprint Baseline quality of life before intensive care: a comparison of patient versus proxy responses
    Jeneen M Gifford
    Department of Internal Medicine, Johns Hopkins Bayview Medical Center, Baltimore, MD, USA
    Crit Care Med 38:855-60. 2010
    ..To compare acute lung injury patients' self-reported, retrospective baseline quality of life before their intensive care hospitalization with population norms and retrospective proxy estimates...
  51. doi request reprint Rehabilitation therapy and outcomes in acute respiratory failure: an observational pilot project
    Jennifer M Zanni
    Department of Physical Medicine and Rehabilitation, Johns Hopkins Hospital, Baltimore, MD 21205, USA
    J Crit Care 25:254-62. 2010
    ..The aim of this study was to describe the frequency, physiologic effects, safety, and patient outcomes associated with traditional rehabilitation therapy in patients who require mechanical ventilation...
  52. doi request reprint Rehabilitation quality improvement in an intensive care unit setting: implementation of a quality improvement model
    Dale M Needham
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
    Top Stroke Rehabil 17:271-81. 2010
    ..We present a specific model for undertaking quality improvement (QI) projects and a case study focused on QI for early PM&R in the ICU...
  53. ncbi request reprint Intensive care unit safety incidents for medical versus surgical patients: a prospective multicenter study
    David J Sinopoli
    UMDNJ Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
    J Crit Care 22:177-83. 2007
    ..The aim of this study is to determine if patient safety incidents and the system-related factors contributing to them systematically differ for medical versus surgical patients in intensive care units...
  54. ncbi request reprint Troponin I and T levels in renal failure patients without acute coronary syndrome: a systematic review of the literature
    Dale M Needham
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Can J Cardiol 20:1212-8. 2004
    ..Debate surrounds the interpretation of troponin assays for the diagnosis and prognosis of cardiac disease in patients with renal failure...
  55. ncbi request reprint An intensivist all day, keeps the bad outcomes away
    Eddy Fan
    Crit Care Med 35:286-7. 2007
  56. ncbi request reprint Mechanical ventilation in Ontario, 1992-2000: incidence, survival, and hospital bed utilization of noncardiac surgery adult patients
    Dale M Needham
    Department of Critical Care Medicine and Medicine, University of Toronto, Toronto, Canada
    Crit Care Med 32:1504-9. 2004
    ..We describe population-based, temporal trends in the incidence, survival, and hospital bed utilization of mechanically ventilated, noncardiac surgery adult patients...
  57. ncbi request reprint The role of future longitudinal studies in ICU survivors: understanding determinants and pathophysiology of weakness and neuromuscular dysfunction
    Catherine L Hough
    Department of Medicine, University of Washington, Seattle, Washington, USA
    Curr Opin Crit Care 13:489-96. 2007
    ..The goals of this review are to discuss the pathophysiology and determinants of muscle weakness and neuromuscular dysfunction after critical illness, and to offer thoughts regarding the role of future longitudinal studies in this area...
  58. ncbi request reprint Informed consent in the critically ill: a two-step approach incorporating delirium screening
    Eddy Fan
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada
    Crit Care Med 36:94-9. 2008
    ..We describe a two-step process for informed consent and evaluate the natural history of patients' competency by repeated application of this process during their hospitalization...
  59. doi request reprint Patient and intensive care unit organizational factors associated with low tidal volume ventilation in acute lung injury
    Nsikak J Umoh
    Department of Surgery, Geisinger Medical Center, Danville, PA, USA
    Crit Care Med 36:1463-8. 2008
    ..Within the intensive care unit (ICU) setting, low tidal volume ventilation (LTVV) in patients with acute lung injury (ALI) significantly decreases mortality. However, LTVV has not achieved widespread adoption...
  60. pmc Deciding who to admit to a critical care unit
    Eddy Fan
    BMJ 335:1103-4. 2007
  61. ncbi request reprint West Nile virus infection in the intensive care unit: a case series and literature review
    Eddy Fan
    Department of Medicine, University of Toronto
    Can Respir J 11:354-8. 2004
    ..West Nile virus (WNV) is a rapidly spreading infectious disease in North America. Critical care issues related to WNV are not well described...
  62. doi request reprint The science of quality improvement
    Eddy Fan
    JAMA 300:390-1; author reply 391-2. 2008
  63. ncbi request reprint Projected incidence of mechanical ventilation in Ontario to 2026: Preparing for the aging baby boomers
    Dale M Needham
    Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada
    Crit Care Med 33:574-9. 2005
    ..We forecast the future incidence of mechanical ventilation to the year 2026 to understand the impact of aging baby boomers on critical care resources...
  64. ncbi request reprint The importance of understanding the costs of critical care and mechanical ventilation
    Dale M Needham
    Crit Care Med 33:1434-5. 2005
  65. ncbi request reprint Ventilatory management of acute lung injury and acute respiratory distress syndrome
    Eddy Fan
    Interdepartmental Division of Critical Care Medicine and Department of Medicine, University of Toronto and University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada
    JAMA 294:2889-96. 2005
    ..However, despite several important advances, the optimal strategy for ventilation and adjunctive therapies for patients with acute lung injury and acute respiratory distress syndrome is still evolving...
  66. ncbi request reprint How will we know patients are safer? An organization-wide approach to measuring and improving safety
    Peter Pronovost
    The Johns Hopkins University, Department of Anesthesiology and Critical Care Medicine, USA
    Crit Care Med 34:1988-95. 2006
    ....
  67. ncbi request reprint Mechanical ventilation and disuse atrophy of the diaphragm
    Eddy Fan
    N Engl J Med 359:90-1; author reply 91-2. 2008
  68. ncbi request reprint Critically appraise before you believe: the quality of meta-analyses in critical care medicine
    Dale M Needham
    Crit Care Med 35:666-7. 2007
  69. ncbi request reprint 24-hour intensivist staffing: balancing benefits and costs
    Adam Sapirstein
    Crit Care Med 36:367-8. 2008
  70. ncbi request reprint A province-wide study of the association between hospital resource allocation and length of stay
    Dale M Needham
    University of Toronto, Toronto, Canada
    Health Serv Manage Res 16:155-66. 2003
    ..Future research should focus on exploring the nature of this relationship and the potential interdependencies among hospital services that cause this effect...

Research Grants4

  1. Patient Outcomes 6 and 12 Months After ALTA, OMEGA and EDEN ARDS Network Trials
    Dale Needham; Fiscal Year: 2009
    ..End of Abstract) ..
  2. Patient Outcomes 6 and 12 Months After ALTA, OMEGA and EDEN ARDS Network Trials
    DALE MURRAY contact NEEDHAM; Fiscal Year: 2010
    ..End of Abstract) ..
  3. Patient Outcomes 6 and 12 Months After ALTA, OMEGA and EDEN ARDS Network Trials
    Dale Needham; Fiscal Year: 2009
    ..End of Abstract) ..