Research Topics
Species | Hind NassarSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9Dengfeng Cao
Departments of Pathology and Immunology, Washington University, St Louis, MO, USA
Breast Cancer Res 10:R91. 2008..Global gene expression profiling of LCIS has not been performed...
Ductal carcinoma in situ in African American versus Caucasian American women: analysis of clinicopathologic features and outcomeHind Nassar
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Cancer 115:3181-8. 2009..The characteristics of ductal carcinoma in situ (DCIS) in the AA population have not been extensively studied...- Pseudoangiomatous stromal hyperplasia (PASH) of the breast with foci of morphologic malignancy: a case of PASH with malignant transformation?Hind Nassar
Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Int J Surg Pathol 18:564-9. 2010..This is perhaps the first case of PASH with foci of malignant histologic features reported in the literature and represents a rare sarcoma derived from specialized hormonally responsive mammary stroma... - Heterogeneity of Bcl-2 expression in metastatic breast carcinomaAndrea Proctor Subhawong
Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
Mod Pathol 23:1089-96. 2010..Instead, downregulation of bcl-2 expression may occur in the setting of hormone therapy resistance. Our findings call into question the potential utility of anti-bcl-2 therapy in metastatic breast cancer... - Relationship between molecular subtype of invasive breast carcinoma and expression of gross cystic disease fluid protein 15 and mammaglobinGloria H Lewis
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Am J Clin Pathol 135:587-91. 2011..Correlation with clinical findings may be needed to exclude the possibility of a metastasis to the breast when BLCs or UTNCs are encountered in a limited sample such as a core biopsy sample... - The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpressionAndrea Proctor Subhawong
Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, USA
Mod Pathol 22:1423-31. 2009..As cancers using the ALT pathway are predicted to be resistant to therapies based on telomerase inhibition, these results may have therapeutic consequences... - MYC gene amplification is often acquired in lethal distant breast cancer metastases of unamplified primary tumorsAatur D Singhi
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Mod Pathol 25:378-87. 2012..These observations underscore the importance of MYC in breast cancer progression/metastasis, as well as its relevance as a potential therapeutic target in otherwise incurable metastatic disease... - Incidental minimal atypical lobular hyperplasia on core needle biopsy: correlation with findings on follow-up excisionAndrea Proctor Subhawong
Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Surg Pathol 34:822-8. 2010..However, management of ALH is controversial. We review our experience with incidental minimal ALH on core biopsy, and correlate with excision and follow-up results... - Pathologic complete response to preoperative sequential doxorubicin/cyclophosphamide and single-agent taxane with or without trastuzumab in stage II/III HER2-positive breast cancerSaranya Chumsri
University of Maryland Greenebaum Cancer Center, Baltimore, MD 21231, USA
Clin Breast Cancer 10:40-5. 2010..We evaluated pathologic complete response (pCR) rate and cardiac safety of preoperative doxorubicin and cyclophosphamide followed by a taxane with or without trastuzumab... - Most basal-like breast carcinomas demonstrate the same Rb-/p16+ immunophenotype as the HPV-related poorly differentiated squamous cell carcinomas which they resemble morphologicallyAndrea Proctor Subhawong
Department of Pathology, The Johns Hopkins Medical Institutions, MD 21231 2410, USA
Am J Surg Pathol 33:163-75. 2009..This subset may represent a more homogenous group than BLC as defined currently... 
Comedo-ductal carcinoma in situ: A paradoxical role for programmed cell deathMalathy P V Shekhar
Breast Cancer Program, Karmanos Cancer Institute, Department of Pathology, Wayne State University, Detroit, Michigan, USA
Cancer Biol Ther 7:1774-82. 2008..It is possible that spontaneous apoptosis facilitates elimination of cells thus permitting expansion and malignant transformation of cancer cells that are resistant to spontaneous apoptosis...- Aberrant expression of X-linked genes RbAp46, Rsk4, and Cldn2 in breast cancerArchana Thakur
Department of Pathology, Karmanos Cancer Institute, Wayne State University, 110 East Warren Avenue, Detroit, MI 48201, USA
Mol Cancer Res 5:171-81. 2007..The activation status of the X-chromosome may influence the expression levels of X-linked oncogenes or tumor suppressor genes... - Pathogenesis of invasive micropapillary carcinoma: role of MUC1 glycoproteinHind Nassar
Department of Pathology, Wayne State University, Harper University Hospital Detroit, MI 48201, USA
Mod Pathol 17:1045-50. 2004.... - Pathogenesis of colloid (pure mucinous) carcinoma of exocrine organs: Coupling of gel-forming mucin (MUC2) production with altered cell polarity and abnormal cell-stroma interaction may be the key factor in the morphogenesis and indolent behavior of colloN Volkan Adsay
Department of Pathology, Karamanos Cancer Institute and Wayne State University, Detroit, Michigan 48201, USA
Am J Surg Pathol 27:571-8. 2003..This distinctive mucin, accumulated in the stroma surrounding the CC cells, may act as a containing factor, slackening the spread of the cells...