K J Murphy

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Percutaneous vertebroplasty in benign and malignant disease
    K J Murphy
    Department of Radiology and Radiological Sciences, The John Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Neuroimaging Clin N Am 10:535-45. 2000
  2. ncbi request reprint Multilevel vertebroplasty via a single pedicular approach using a curved 13-gauge needle: technical note
    Kieran J Murphy
    Division of Interventional Neuroradiology, Department of Radiology and Radiological Sciences, Johns Hopkins Hospital, 600 North Wolfe St, Baltimore, MD 21287
    Can Assoc Radiol J 53:293-5. 2002
  3. doi request reprint CT fluoroscopy-guided postmyelographic transthecal radiofrequency ablation of a posterior vertebral body osteoid osteoma
    Kieran Murphy
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Radiology B 100, Baltimore, MD 21287 2182, USA
    J Vasc Interv Radiol 19:291-3. 2008
  4. doi request reprint Development of a research agenda for skeletal intervention: proceedings from a multidisciplinary consensus panel
    Kieran J Murphy
    Department of Radiology, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21287, USA
    J Vasc Interv Radiol 19:631-8. 2008
  5. ncbi request reprint CT fluoroscopy: novel application for the treatment of ventricular pathologies
    Kieran Murphy
    Interventional Neuroradiology, Johns Hopkins Hospital, Baltimore, MD, USA
    Neuroradiology 49:373-8. 2007
  6. pmc Detection of FLT3 internal tandem duplication and D835 mutations by a multiplex polymerase chain reaction and capillary electrophoresis assay
    Kathleen M Murphy
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21287, USA
    J Mol Diagn 5:96-102. 2003
  7. ncbi request reprint Vertebroplasty: a simple solution to a difficult problem
    K J Murphy
    Intervention Neuroradiology, Department of Radiology and Radiologic Science, Johns Hopkins Medical Institution, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Clin Densitom 4:189-97. 2001
  8. ncbi request reprint Sequencing of genomic DNA by combined amplification and cycle sequencing reaction
    Kathleen M Murphy
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Clin Chem 51:35-9. 2005
  9. ncbi request reprint ISAT and ISUIA: the impact on informed consent
    Kieran Murphy
    Department of Radiology and Neurosurgery, Johns Hopkins Medical Institution, Baltimore, MD 21287, USA
    Tech Vasc Interv Radiol 8:106-7. 2005
  10. ncbi request reprint Mechanical detachable platinum coil: report of the European phase II clinical trial in 60 patients
    K J Murphy
    Div of Diagnostic and Interventional Radiology, Geneva Univ Hospital, Switzerland
    Radiology 219:541-4. 2001

Detail Information

Publications56

  1. ncbi request reprint Percutaneous vertebroplasty in benign and malignant disease
    K J Murphy
    Department of Radiology and Radiological Sciences, The John Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Neuroimaging Clin N Am 10:535-45. 2000
    ..The few complications reported have been related to excessive PMMA injection, underlining the need for excellent imaging conditions to control the cement injection...
  2. ncbi request reprint Multilevel vertebroplasty via a single pedicular approach using a curved 13-gauge needle: technical note
    Kieran J Murphy
    Division of Interventional Neuroradiology, Department of Radiology and Radiological Sciences, Johns Hopkins Hospital, 600 North Wolfe St, Baltimore, MD 21287
    Can Assoc Radiol J 53:293-5. 2002
  3. doi request reprint CT fluoroscopy-guided postmyelographic transthecal radiofrequency ablation of a posterior vertebral body osteoid osteoma
    Kieran Murphy
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Radiology B 100, Baltimore, MD 21287 2182, USA
    J Vasc Interv Radiol 19:291-3. 2008
    ..After computed tomographic (CT) myelography, CT fluoroscopy was used to guide the transthecal approach of the RF ablation procedure...
  4. doi request reprint Development of a research agenda for skeletal intervention: proceedings from a multidisciplinary consensus panel
    Kieran J Murphy
    Department of Radiology, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21287, USA
    J Vasc Interv Radiol 19:631-8. 2008
  5. ncbi request reprint CT fluoroscopy: novel application for the treatment of ventricular pathologies
    Kieran Murphy
    Interventional Neuroradiology, Johns Hopkins Hospital, Baltimore, MD, USA
    Neuroradiology 49:373-8. 2007
    ....
  6. pmc Detection of FLT3 internal tandem duplication and D835 mutations by a multiplex polymerase chain reaction and capillary electrophoresis assay
    Kathleen M Murphy
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21287, USA
    J Mol Diagn 5:96-102. 2003
    ..Here we describe the performance characteristics of the assay, assay validation, and our clinical experience using this assay to analyze 147 clinical specimens...
  7. ncbi request reprint Vertebroplasty: a simple solution to a difficult problem
    K J Murphy
    Intervention Neuroradiology, Department of Radiology and Radiologic Science, Johns Hopkins Medical Institution, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Clin Densitom 4:189-97. 2001
    ..It is a safe and simple outpatient procedure. We discuss patient selection, the techniques, and the results based on our experience and that of our radiology colleagues...
  8. ncbi request reprint Sequencing of genomic DNA by combined amplification and cycle sequencing reaction
    Kathleen M Murphy
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Clin Chem 51:35-9. 2005
    ..Our aim was to develop a method to routinely combine PCR amplification and cycle sequencing into one single reaction, enabling direct sequencing of genomic DNA...
  9. ncbi request reprint ISAT and ISUIA: the impact on informed consent
    Kieran Murphy
    Department of Radiology and Neurosurgery, Johns Hopkins Medical Institution, Baltimore, MD 21287, USA
    Tech Vasc Interv Radiol 8:106-7. 2005
    ..The investigators used the term "clinical equipoise" to describe this balance. This study more than any other has set the playing field for the future of interventional radiology/endovascular neurosurgery politics...
  10. ncbi request reprint Mechanical detachable platinum coil: report of the European phase II clinical trial in 60 patients
    K J Murphy
    Div of Diagnostic and Interventional Radiology, Geneva Univ Hospital, Switzerland
    Radiology 219:541-4. 2001
    ..To determine the safety and reliability of the mechanical detachment system of a platinum coil (Detach-18) when used for neurovascular embolization...
  11. ncbi request reprint Role of the distal balloon protection technique in the prevention of cerebral embolic events during carotid stent placement
    J B Martin
    Department of Radiology, Geneva University Hospital, Geneva, Switzerland
    Stroke 32:479-84. 2001
    ..We sought to quantitatively and qualitatively evaluate the release of atheromatous plaque debris induced by carotid stenting procedures...
  12. ncbi request reprint FLT3 mutations in myeloid sarcoma
    M Ali Ansari-Lari
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Br J Haematol 126:785-91. 2004
    ....
  13. ncbi request reprint Molecular diagnosis of oligodendroglioma in paraffin sections
    Kimmo J Hatanpaa
    Division of Neuropathology, The Johns Hopkins University, Baltimore, Maryland, USA
    Lab Invest 83:419-28. 2003
    ..Because only a paraffin section is required, the pathologist can perform both the traditional histopathologic evaluation and this supporting molecular assay from the material at hand...
  14. ncbi request reprint Anatomic relationship between arachnoid granulations in the transverse sinus and the termination of the vein of Labbé: an angiographic study
    P Gailloud
    Department of Radiology and Radiological Sciences, Johns Hopkins Hospital, 600 North Wolfe Street Baltimore, MD 21287, USA
    Neuroradiology 43:139-43. 2001
    ..The constant character of this relationship suggests a developmental role of afferent veins in the formation of arachnoid granulations...
  15. doi request reprint Complex rearrangement of chromosomes 1, 7, 21, 22 in Ewing sarcoma
    Natini Jinawath
    Institute of Genetic Medicine, Johns Hopkins Medical Institutions, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Cancer Genet Cytogenet 201:42-7. 2010
    ..This case adds to the spectrum of genetic rearrangements identified in ES tumors...
  16. ncbi request reprint Pooling of echographic contrast agents during transcranial Doppler sonography: a sign in favor of slow-flowing giant saccular aneurysms
    P Gailloud
    Division of Diagnostic and Interventional Radiology, Geneva University Hospital, Switzerland
    Neuroradiology 44:21-4. 2002
    ..Knowledge of atypical or contrast-specific lesion appearances will become important if contrast-enhanced TCD is to be used routinely in the diagnosis of intracranial aneurysms...
  17. ncbi request reprint Multicolor fluorescence in situ hybridization (SKY) in mycosis fungoides and Sézary syndrome: search for recurrent chromosome abnormalities
    Denise A S Batista
    Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Genes Chromosomes Cancer 45:383-91. 2006
    ..2;p11.2). Two patients with SS reported in the literature seem to have a similar translocation. If confirmed, a psu dic(17;8) could be the first recurring translocation detected in at least three patients with MF/SS...
  18. ncbi request reprint Overexpression of claudin proteins in esophageal adenocarcinoma and its precursor lesions
    Elizabeth Montgomery
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21230, USA
    Appl Immunohistochem Mol Morphol 14:24-30. 2006
    ..The findings suggest that alterations in Claudin proteins are an early event in tumorigenesis and may provide targets for diagnosis and directed therapy for esophageal adenocarcinoma and its precursors...
  19. pmc Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implications
    Athanasios C Tsiatis
    The Johns Hopkins Medical Institutions, Department of Pathology, 600 N Wolfe Street, Park SB202, Baltimore, MD 21287, USA
    J Mol Diagn 12:425-32. 2010
    ..1% false positives and 6.1% false negatives. In our hands, the limit of detection for Sanger sequencing, pyrosequencing, and melting curve analysis was approximately 15 to 20%, 5%, and 10% mutant alleles, respectively...
  20. ncbi request reprint Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: a model for patient classification to aid fluoropyrimidine therapy
    Jonathan R Brody
    The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Cancer Res 66:9369-73. 2006
    ..The data suggest that TS copy number in a patient's tumor may be a dominating variable affecting 5FU responsiveness...
  21. pmc Molecular genotyping of hydatidiform moles: analytic validation of a multiplex short tandem repeat assay
    Kathleen M Murphy
    Department of Pathology, Johns Hopkins Medical Institutions, Park Bldg Room SB202, 600 North Wolfe St, Baltimore, MD 21287, USA
    J Mol Diagn 11:598-605. 2009
    ..To avoid these pitfalls, we have developed an algorithm with quantitative guidelines for the interpretation of short tandem repeat genotyping data...
  22. ncbi request reprint Identification of der(1;19)(q10;p10) in five oligodendrogliomas suggests mechanism of concurrent 1p and 19q loss
    Constance A Griffin
    Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21287, USA
    J Neuropathol Exp Neurol 65:988-94. 2006
    ..Subsequent loss of the der(1;19)(p10;q10) then results in the simultaneous 1p and 19q loss observed in oligodendroglioma with retention of the der(1;19)(q10;p10) seen in these cases...
  23. ncbi request reprint Use of T-cell antibodies for donor dosaging in a canine model of in utero hematopoietic stem cell transplantation
    Scott M Petersen
    Department of Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Fetal Diagn Ther 22:175-9. 2007
    ..Microchimerism following canine in utero hematopoietic stem cell transplantation (IUHSCT) development of T-cell dosing regimens...
  24. doi request reprint Complete hydatidiform mole with retained maternal chromosomes 6 and 11
    Thomas G McConnell
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Am J Surg Pathol 33:1409-15. 2009
    ..Genome-wide analysis has the potential to assist in localizing imprinted genes critical for determining the morphologic and behavioral phenotypes of hydatidiform moles...
  25. pmc Constitutional duplication of a region of chromosome Yp encoding AMELY, PRKY, and TBL1Y: implications for sex chromosome analysis and bone marrow engraftment analysis
    Kathleen M Murphy
    Department of Pathology, John Hopkins Medical Institutions, Baltimore, MD, USA
    J Mol Diagn 9:408-13. 2007
    ..Although this and other genetic variants involving AMELY are uncommon, one should use caution when using amelogenin for sex chromosome analysis and bone marrow engraftment analysis...
  26. ncbi request reprint BCR/ABL rearrangement in two cases of Philadelphia chromosome negative chronic myeloid leukemia: deletion on the derivative chromosome 9 may or not be present
    Denise A S Batista
    Department of Pathology, Division of Molecular Pathology, Johns Hopkins University, 600 North Wolfe Street, Park SB 202, Baltimore, MD 21287, USA
    Cancer Genet Cytogenet 163:164-7. 2005
    ..Some authors reported that patients with the chimeric gene located on the derivative 9 have a poor clinical course. We suggest that deletion rather than location of the chimeric gene alone is more likely to be associated with prognosis...
  27. ncbi request reprint Mutation and single nucleotide polymorphism detection using temperature gradient capillary electrophoresis
    Kathleen M Murphy
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Expert Rev Mol Diagn 3:811-8. 2003
    ..The utility of temperature gradient capillary electrophoresis for the detection of known sequence alterations and as a tool for mutation discovery is reviewed...
  28. pmc A single nucleotide primer extension assay to detect the APC I1307K gene variant
    Kathleen M Murphy
    Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Mol Diagn 5:222-6. 2003
    ..The single nucleotide extension assay provides a highly sensitive and specific assay to identify individuals with the APC I1307K gene variant who may benefit from increased colorectal screening...
  29. pmc Internal tandem duplications of the FLT3 gene are present in leukemia stem cells
    Mark Levis
    Blood 106:673-80. 2005
    ..Taken together, these experiments establish that the FLT3/ITD mutations are present in leukemia stem cells, and that FLT3 inhibitors may have activity against these cells...
  30. ncbi request reprint Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia
    B Douglas Smith
    Departments of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA
    Blood 103:3669-76. 2004
    ..Our results show that FLT3 inhibition is associated with clinical activity in AML patients harboring FLT3-activating mutations and indicate that CEP-701 holds promise as a novel, molecularly targeted therapy for this disease...
  31. ncbi request reprint In vitro evaluation of the effectiveness of distal protection in the prevention of cerebral thromboembolism during carotid stent placement
    J B Martin
    Department of Radiology, University Hospital of Geneva, Switzerland
    Acad Radiol 8:623-8. 2001
    ..CONCLUSION: In vitro evaluation of the distal flow protection technique indicates that it should reduce stroke risk during carotid stent placement...
  32. pmc A molecular fraction collecting tool for the ABI 310 automated sequencer
    Ming Tseh Lin
    The Sol Goldman Pancreatic Cancer Research Center, Departments of Pathology and Oncology, Johns Hopkins School of Medicine, 1550 Orleans Street, Baltimore, MD 21231, USA
    J Mol Diagn 9:598-603. 2007
    ..In addition, we successfully isolated bands that were only three bases apart that comigrated on polyacrylamide gel electrophoresis. DNA sequencing was used to confirm that the correct peaks were recovered at sufficient purity...
  33. pmc Molecular diagnosis of metastasizing oligodendroglioma: a case report
    Min Wang
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Mol Diagn 6:52-7. 2004
    ..This analysis revealed evidence of LOH at all eight of the microsatellite loci tested. The combination of cytologic and molecular findings defined the extracranial tumor to be metastatic oligodendroglioma...
  34. doi request reprint Diagnosis and subclassification of hydatidiform moles using p57 immunohistochemistry and molecular genotyping: validation and prospective analysis in routine and consultation practice settings with development of an algorithmic approach
    Thomas G McConnell
    Department of Pathology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 33:805-17. 2009
    ....
  35. pmc A rare e14a3 (b3a3) BCR-ABL fusion transcript in chronic myeloid leukemia: diagnostic challenges in clinical laboratory practice
    Natini Jinawath
    Institute of Genetic Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Mol Diagn 11:359-63. 2009
    ....
  36. pmc FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML
    Keith W Pratz
    Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21231, USA
    Blood 115:1425-32. 2010
    ..These results have important implications for the potential therapeutic use of FLT3 inhibitors in that patients with newly diagnosed FLT3-mutant AML might be less likely to respond clinically to highly selective FLT3 inhibition...
  37. pmc Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas
    Vikki Rand
    Department of Neurosurgery, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Baltimore, MD 21224, USA
    Proc Natl Acad Sci U S A 102:14344-9. 2005
    ..Our results demonstrate the utility of applying DNA sequencing technology to systematically assess the coding sequence of genes within cancer genomes...
  38. ncbi request reprint Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers
    Paula M Hempen
    Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21231, USA
    Cancer Res 63:994-9. 2003
    ..This evidence is compatible with a high degree of selection for inactivation of the ACVR2 gene in tumorigenesis, supporting ACVR2 as a candidate tumor suppressor gene in gastrointestinal cancers...
  39. pmc Abnormal villous morphology associated with triple trisomy of paternal origin
    Alexis Norris-Kirby
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Mol Diagn 12:525-9. 2010
    ..The three trisomies may have originated from paternal meiosis II errors, or from mitotic nondisjunction. We believe this to be the first report of triple trisomy in a SAB confirmed to be of paternal origin...
  40. pmc Bone marrow engraftment analysis after granulocyte transfusion
    Sharon L Swierczynski
    Department of Pathology, Johns Hopkins Medical Institutions, Park Building, Room SB202, 600 North Wolfe St, Baltimore, MD 21287, USA
    J Mol Diagn 7:422-6. 2005
    ..This case illustrates that white cell transfusion can lead to erroneous bone marrow engraftment results, particularly if only one microsatellite locus is used to monitor engraftment...
  41. pmc Comparison of the microsatellite instability analysis system and the Bethesda panel for the determination of microsatellite instability in colorectal cancers
    Kathleen M Murphy
    Department of Pathology, Johns Hopkins University School of Medicine, USA
    J Mol Diagn 8:305-11. 2006
    ..Our results suggest that the MSI Analysis System is generally superior and may help resolve cases of MSI-low into either MSI-high or MSS...
  42. pmc Capillary electrophoresis artifact due to eosin: implications for the interpretation of molecular diagnostic assays
    Kathleen M Murphy
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Mol Diagn 7:143-8. 2005
    ..Histological dyes may fluoresce, and artifacts from them should be considered when primary peaks contain additional underlying peaks of other colors...
  43. ncbi request reprint Identification of novel highly expressed genes in pancreatic ductal adenocarcinomas through a bioinformatics analysis of expressed sequence tags
    Dengfeng Cao
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 3:1081-9; discussion 1090-1. 2004
    ....
  44. ncbi request reprint Cook detachable coil embolization of a symptomatic, isolated orbital arteriovenous fistula via a superior ophthalmic vein approach
    P S Subramanian
    Department of Ophthalmology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Neuroradiology 47:62-5. 2005
    ..We describe the clinical presentation and treatment of a spontaneous arteriovenous fistula of the right posterior orbit via a superior ophthalmic vein approach for embolization using platinum detachable coils...
  45. ncbi request reprint Vascular compression by a ventricular shunt catheter: clinical value of volume-rendered CT angiography
    P Gailloud
    Neuroradiology Division, Department of Radiology and Radiological Sciences, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    AJNR Am J Neuroradiol 22:1570-1. 2001
    ....
  46. doi request reprint Interstitial microduplication of Xp22.31: Causative of intellectual disability or benign copy number variant?
    Feng Li
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA
    Eur J Med Genet 53:93-9. 2010
    ..To date, this report is the largest compilation of clinical and array data regarding the microduplication of Xp22.31 and will serve to broaden the knowledge of regions involving copy number variation (CNV)...
  47. ncbi request reprint RANBP2 and CLTC are involved in ALK rearrangements in inflammatory myofibroblastic tumors
    Ankita S Patel
    Department of Pathology, Johns Hopkins University, Park SB 202, 600 N Wolfe Street, Baltimore MD 21287, USA
    Cancer Genet Cytogenet 176:107-14. 2007
    ....
  48. ncbi request reprint Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%
    Kathleen M Murphy
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Res 62:3789-93. 2002
    ..These findings confirm the increased risk of pancreatic cancer in individuals with BRCA2 mutations and identify germ-line BRCA2 mutations as the most common inherited genetic alteration yet identified in familial pancreatic cancer...
  49. pmc Simultaneous sequencing of multiple polymerase chain reaction products and combined polymerase chain reaction with cycle sequencing in single reactions
    Kathleen M Murphy
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Am J Pathol 161:27-33. 2002
    ..We anticipate that these methods will have utility in research and clinical settings where panels of mutations or large numbers of samples are be analyzed and/or when turnaround time is critical...
  50. doi request reprint Identification of immunohistochemical biomarkers for papillary thyroid carcinoma using gene expression profiling
    Kathleen M Murphy
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Hum Pathol 39:420-6. 2008
    ..These results validate our approach for PTC biomarker discovery and identify several candidate biomarkers for further development...
  51. ncbi request reprint High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter
    Taylor A Sohn
    Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Carcinogenesis 23:949-57. 2002
    ....
  52. pmc Application of traditional clinical pathology quality control techniques to molecular pathology
    Shu Ling Liang
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Mol Diagn 10:142-6. 2008
    ..By incorporating these tools into an overall quality assurance program, a laboratory can identify systematic errors and perform corrective actions before actual assay failure, thereby improving the quality of patient care...
  53. ncbi request reprint Detecting low-abundance p16 and p53 mutations in pancreatic juice using a novel assay: heteroduplex analysis of limiting dilution PCRs
    Yansong Bian
    Department of Pathology, The Sol Goldman Center for Pancreatic Cancer Research, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
    Cancer Biol Ther 5:1392-9. 2006
    ....
  54. pmc Evaluation of the Cepheid GeneXpert BCR-ABL assay
    Zsolt Jobbagy
    Molecular Diagnostics Laboratory, Department of Pathology, Johns Hopkins Medical Institutions, 600 N Wolfe St, Park SB 202, Baltimore, MD 21287, USA
    J Mol Diagn 9:220-7. 2007
    ....
  55. ncbi request reprint Clonal cytogenetic abnormalities and BCL2 rearrangement in interdigitating dendritic cell sarcoma
    Hassan Nayer
    Leuk Lymphoma 47:2651-4. 2006
  56. ncbi request reprint Immunodetecting members of the Bcl-2 family of proteins
    Richard B Lock
    Children s Cancer Institute Australia for Medical Research, South Australia, Sydney
    Methods Mol Med 111:83-96. 2005
    ..In addition, the methodology describes how conformational changes can be observed by immunofluorescence and immunoprecipitation, and how subcellular redistribution of Bcl-2 homologs can be followed...