Research Topics
| LUKE MULLANYSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
Research Grants
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Detail Information
Publications
Impact of 4.0% chlorhexidine cord cleansing on the bacteriologic profile of the newborn umbilical stump in rural Sylhet District, Bangladesh: a community-based, cluster-randomized trialLuke C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Pediatr Infect Dis J 31:444-50. 2012..Such data could clarify the design of scaled chlorhexidine interventions...- Clean birth and postnatal care practices to reduce neonatal deaths from sepsis and tetanus: a systematic review and Delphi estimation of mortality effectHannah Blencowe
London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
BMC Public Health 11:S11. 2011..Annually over 520,000 newborns die from neonatal sepsis, and 60,000 more from tetanus. Estimates of the effect of clean birth and postnatal care practices are required for evidence-based program planning... - Impact of 4.0% chlorhexidine cleansing of the umbilical cord on mortality and omphalitis among newborns of Sylhet, Bangladesh: design of a community-based cluster randomized trialLuke C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
BMC Pediatr 9:67. 2009..A previous trial in Nepal indicated that umbilical cord cleansing with 4.0% chlorhexidine could substantially reduce mortality and omphalitis risk, but policy changes await additional community-based data... - Breast-feeding patterns, time to initiation, and mortality risk among newborns in southern NepalLuke C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Nutr 138:599-603. 2008..Community-based breast-feeding promotion programs should remain a priority, with renewed emphasis on early initiation in addition to exclusiveness and duration of breast-feeding... - A randomized controlled trial of the impact of chlorhexidine skin cleansing on bacterial colonization of hospital-born infants in NepalLuke C Mullany
International Center for Advancing Neonatal Health, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Pediatr Infect Dis J 27:505-11. 2008..Few data exist on the impact of chlorhexidine cleansing on skin colonization of infants during the first day of life or on the absorption potential of chlorhexidine during newborn skin cleansing... - Neonatal hypothermia and associated risk factors among newborns of southern NepalLuke C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N, Wolfe Street, Baltimore, MD 21205, USA
BMC Med 8:43. 2010..Estimates of association between neonatal hypothermia in the community and risk factors are needed to guide the design of interventions to reduce exposure... - The MOM Project: delivering maternal health services among internally displaced populations in eastern BurmaLuke C Mullany
Johns Hopkins Center for Public Health and Human Rights, Baltimore MD, USA
Reprod Health Matters 16:44-56. 2008..This innovative obstetric health care delivery strategy may serve as a model for the delivery of other essential health services in this population and for increasing access to care in other conflict settings... - Risk of mortality subsequent to umbilical cord infection among newborns of southern Nepal: cord infection and mortalityLuke C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Pediatr Infect Dis J 28:17-20. 2009..We compared the risk of mortality between infants with and without signs of umbilical cord infection during a community-based trial of chlorhexidine interventions in southern Nepal... - Access to essential maternal health interventions and human rights violations among vulnerable communities in eastern BurmaLuke C Mullany
Center for Public Health and Human Rights, Bloomberg School of Public Health, Baltimore, Maryland, USA
PLoS Med 5:1689-98. 2008..The goal of this study is to estimate coverage of maternal health services prior to this project and associations between exposure to human rights violations and access to such services... - Incidence and risk factors for newborn umbilical cord infections on Pemba Island, Zanzibar, TanzaniaLuke C Mullany
Department of International Health, John Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Pediatr Infect Dis J 28:503-9. 2009..We developed simple sign-based definitions of omphalitis and estimated incidence and risk factors for infection over a range of severity among neonates in Pemba, Zanzibar, Tanzania... - Incidence and seasonality of hypothermia among newborns in southern NepalLuke C Mullany
International Center for Advancing Neonatal Health, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Ste E8646, Baltimore, MD 21205, USA
Arch Pediatr Adolesc Med 164:71-7. 2010..To quantify incidence, age distribution, and seasonality of neonatal hypothermia among a large population cohort... - Risk of mortality associated with neonatal hypothermia in southern NepalLuke C Mullany
Department of International Health, Bloomberg School of Public Health, Baltimore, MD 21205, USA
Arch Pediatr Adolesc Med 164:650-6. 2010..To quantify the neonatal mortality/hypothermia relationship and develop evidence-based cutoffs for global definitions of neonatal hypothermia... - Impact of community-based maternal health workers on coverage of essential maternal health interventions among internally displaced communities in eastern Burma: the MOM projectLuke C Mullany
Center for Public Health and Human Rights, Johns Hopkins Bloomberg School of Public Health Bloomberg School of Public Health, Baltimore, Maryland, USA
PLoS Med 7:e1000317. 2010..In such settings, innovative strategies for accessing vulnerable populations and delivering basic public health interventions are urgently needed... - Neonatal hypothermia in low-resource settingsLuke C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Semin Perinatol 34:426-33. 2010..Context-appropriate interventions for reducing hypothermia exposure and the role of these interventions in reducing global neonatal mortality burden are explored... - Population-based survey methods to quantify associations between human rights violations and health outcomes among internally displaced persons in eastern BurmaLuke C Mullany
Center for Public Health and Human Rights, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Epidemiol Community Health 61:908-14. 2007..Case reports of human rights violations have focused on individuals' experiences. Population-based quantification of associations between rights indicators and health outcomes is rare and has not been documented in eastern Burma... - HIV/AIDS knowledge, attitudes, and practices among Burmese migrant factory workers in Tak Province, ThailandL C Mullany
Department of International Health, Johns Hopkins University School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
AIDS Care 15:63-70. 2003..The survey reveals a significant lack of knowledge about HIV among factory workers and indicates that a sub-population of Burmese people appears to lack the most basic information about the epidemic... - Traditional massage of newborns in Nepal: implications for trials of improved practiceLuke C Mullany
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Trop Pediatr 51:82-6. 2005.... - Development of clinical sign based algorithms for community based assessment of omphalitisL C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Suite W5021, Baltimore, MD 21211, USA
Arch Dis Child Fetal Neonatal Ed 91:F99-104. 2006..In developing countries, newborn omphalitis contributes significantly to morbidity and mortality. Community based identification and management of omphalitis will require standardised clinical sign based definitions... - Relationship between the surrogate anthropometric measures, foot length and chest circumference and birth weight among newborns of Sarlahi, NepalL C Mullany
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205 2103, USA
Eur J Clin Nutr 61:40-6. 2007..Classification of infants into low birth weight (LBW, <2500 g) or very low birth weight (VLBW, <2000 g) categories is a crucial step in targeting interventions to high-risk infants... - Topical applications of chlorhexidine to the umbilical cord for prevention of omphalitis and neonatal mortality in southern Nepal: a community-based, cluster-randomised trialLuke C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21211, USA
Lancet 367:910-8. 2006..Omphalitis contributes to neonatal morbidity and mortality in developing countries. Umbilical cord cleansing with antiseptics might reduce infection and mortality risk, but has not been rigorously investigated... - Role of antimicrobial applications to the umbilical cord in neonates to prevent bacterial colonization and infection: a review of the evidenceLuke C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Room W5009, Baltimore, MD 21205 2103, USA
Pediatr Infect Dis J 22:996-1002. 2003..quot; The paucity of published reports from developing countries indicates the need to investigate the impact of antimicrobial applications on cord and systemic infections in a community-based, prospective manner... - Safety and impact of chlorhexidine antisepsis interventions for improving neonatal health in developing countriesLuke C Mullany
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21211, USA
Pediatr Infect Dis J 25:665-75. 2006..Efficacy trials for all chlorhexidine interventions are needed in low-resource settings in Africa, and the benefit of maternal vaginal cleansing beyond that provided by newborn skin cleansing needs to be determined... - Risk factors for umbilical cord infection among newborns of southern NepalLuke C Mullany
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21211, USA
Am J Epidemiol 165:203-11. 2007..In addition to topical antiseptics, simple, low-cost interventions such as hand washing, skin-to-skin contact, and avoiding unclean cord applications should be promoted by community-based health workers... - Impact of umbilical cord cleansing with 4.0% chlorhexidine on time to cord separation among newborns in southern Nepal: a cluster-randomized, community-based trialLuke C Mullany
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, W5009, Baltimore, MD 21211, USA
Pediatrics 118:1864-71. 2006..0% chlorhexidine on omphalitis and mortality risk, we aimed to describe the distribution of times to separation and the impact of topical chlorhexidine treatment on cord-separation times... - Maternal and birth attendant hand washing and neonatal mortality in southern NepalVictor Rhee
Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205 2103, USA
Arch Pediatr Adolesc Med 162:603-8. 2008..More than 95% of neonatal deaths occur in developing countries, approximately 50% at home. Few data are available on the impact of hand-washing practices by birth attendants or caretakers on neonatal mortality... - Responding to AIDS, tuberculosis, malaria, and emerging infectious diseases in Burma: dilemmas of policy and practiceChris Beyrer
Center for Public Health and Human Rights, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
PLoS Med 3:e393. 2006 - Safety and effect of chlorhexidine skin cleansing on skin flora of neonates in BangladeshGary L Darmstadt
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Pediatr Infect Dis J 26:492-5. 2007..This study examined the impact of a single skin cleansing of hospitalized newborn infants in Bangladesh with baby wipes containing 0.25% chlorhexidine on both qualitative and quantitative skin flora... - Zinc modifies the association between nasopharyngeal Streptococcus pneumoniae carriage and risk of acute lower respiratory infection among young children in rural NepalChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Nutr 138:2462-7. 2008..09; P = 0.006) than in the zinc group (AMOR = 2.77; P = 0.288). These findings suggest that zinc prophylaxis may protect children against ALRI associated with carriage of Spn and that the effect may differ by infectious etiology... - Impact of newborn skin-cleansing with chlorhexidine on neonatal mortality in southern Nepal: a community-based, cluster-randomized trialJames M Tielsch
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Pediatrics 119:e330-40. 2007..Our objective was to assess the efficacy of a 1-time skin-cleansing of newborn infants with 0.25% chlorhexidine on neonatal mortality... - Ancillary care in community-based public health intervention researchMaria W Merritt
Berman Institute of Bioethics, Johns Hopkins University, 615 N Wolfe St, Suite E8132, Baltimore MD 21205, USA
Am J Public Health 100:211-6. 2010.... - Nasopharyngeal carriage of S. pneumoniae among young children in rural NepalChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Trop Med Int Health 14:1025-33. 2009..To provide epidemiologic data on Streptococcus pneumoniae (Spn) carriage in Nepal... - Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trialJames M Tielsch
Center for Human Nutrition and the Sight and Life Institute, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
Lancet 367:144-52. 2006..Supplementation with iron and folic acid alleviates severe anaemia and enhances neurodevelopment in deficient populations, but little is known about the risks of mortality and morbidity associated with supplementation... - Potential role of traditional birth attendants in neonatal healthcare in rural southern NepalTina Y Falle
Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, E8646, Baltimore, MD 21205, USA
J Health Popul Nutr 27:53-61. 2009..Continuing efforts to define the role of TBAs may benefit from an emphasis on their potential as active promoters of essential newborn care... - Young maternal age and the risk of neonatal mortality in rural NepalVandana Sharma
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205 2103, USA
Arch Pediatr Adolesc Med 162:828-35. 2008..To investigate the relationship between adolescent pregnancy and neonatal mortality in a nutritionally deprived population in rural Nepal, and to determine mechanisms through which low maternal age may affect neonatal mortality... - Daily supplementation with iron plus folic acid, zinc, and their combination is not associated with younger age at first walking unassisted in malnourished preschool children from a deficient population in rural NepalJoanne Katz
Department of International Health and 6Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Nutr 140:1317-21. 2010..5 cm [60.6 d, (95% CI: 28.5, 92.6)]. Risks and benefits of universal iron+folic acid supplementation of infants beyond improved hematologic status deserve further consideration... - Effect of daily zinc supplementation on child mortality in southern Nepal: a community-based, cluster randomised, placebo-controlled trialJames M Tielsch
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205 2013, USA
Lancet 370:1230-9. 2007..However, whether routine supplementation would decrease morbidity and mortality in populations with zinc deficiency is unclear. We assessed the effect of daily zinc supplementation on children in southern Nepal... - Verbal autopsy methods to ascertain birth asphyxia deaths in a community-based setting in southern NepalAnne C C Lee
International Center for Advancing Neonatal Health, Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe St, Baltimore, MD 21205, USA
Pediatrics 121:e1372-80. 2008.... - Safety of neonatal skin cleansing in rural NepalLuke C Mullany
Department of International Health and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Indian Pediatr 43:117-24. 2006..This procedure is safe and appropriate precautions can be taken to deliver safe skin antisepsis with chlorhexidine to infants in the community... - Pregnancy-related mortality in southern Nepal between 2001 and 2006: independent estimates from a prospective, population-based cohort and a direct sisterhood surveyDavid W Wee
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Am J Epidemiol 172:855-60. 2010..Access to life-saving maternal health interventions remains low in rural Nepal, and continued efforts are necessary to ensure equitable and country-wide progress toward Millennium Development Goal 5... - Risk factors for neonatal mortality due to birth asphyxia in southern Nepal: a prospective, community-based cohort studyAnne C C Lee
Department of International Health, International Center for Advancing Neonatal Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe St, Baltimore, MD 21205, USA
Pediatrics 121:e1381-90. 2008..Our goal was to identify antepartum, intrapartum, and infant risk factors for birth asphyxia mortality in a rural, low-resource, population-based cohort in southern Nepal... - Simplified age-weight mortality risk classification for very low birth weight infants in low-resource settingsRebecca E Rosenberg
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Pediatr 153:519-24. 2008..To identify a valid neonatal mortality risk prediction score feasible for use in developing countries... - Effect of instrument precision on estimation of low birth weight prevalenceLuke C Mullany
Department of International Health, Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Perinatol 25:11-3. 2005..Conclusions concerning programmatic or research intervention impact, or comparisons of rates across populations should consider the effect of instrument precision on estimates of LBW... - Mortality rates in conflict zones in Karen, Karenni, and Mon states in eastern BurmaThomas J Lee
Department of Medicine, UCLA School of Medicine, University of California Los Angeles, 924 Westwood Boulevard, Los Angeles, CA 90024, USA
Trop Med Int Health 11:1119-27. 2006..To estimate mortality rates for populations living in civil war zones in Karen, Karenni, and Mon states of eastern Burma... - The use of chlorhexidine to reduce maternal and neonatal mortality and morbidity in low-resource settingsE M McClure
Department of Statistics and Epidemiology, RTI International, Durham, NC 27709, USA
Int J Gynaecol Obstet 97:89-94. 2007..It also summarizes issues related to programmatic implementation...
Research Grants
- Incidence, risk factors, and consequences of neonatal hypothermia in NepalLUKE MULLANY; Fiscal Year: 2007..Examination of alternate cutoffs for defining hypothermia severity may improve design of low-cost technologies for identification and subsequent management of hypothermic infants in the community. ..
- Impact of Sunflower Oil Massage on Neonatal Mortality in NepalLuke C Mullany; Fiscal Year: 2010..If efficacious, sunflower seed oil can be promoted as a simple, low-cost intervention that can save the lives of babies in low-resource communities where mortality rates are highest. ..