Research Topics
| W J MossSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Safety and efficacy of zinc supplementation for children with HIV-1 infection in South Africa: a randomised double-blind placebo-controlled trialRaziya Bobat
Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
Lancet 366:1862-7. 2005..In view of the reductions in diarrhoea and pneumonia morbidity, zinc supplementation should be used as adjunct therapy for children with HIV-1 infection...- A sensitive genotyping assay for detection of drug resistance mutations in reverse transcriptase of HIV-1 subtypes B and C in samples stored as dried blood spots or frozen RNA extractsCarrie Ziemniak
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Virol Methods 136:238-47. 2006..This sensitive and reproducible genotypic assay is feasible for detection of antiretroviral resistance in resource-constrained settings... 
Neonatal survival interventions in humanitarian emergencies: a survey of current practices and programsJennifer O Lam
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Confl Health 6:2. 2012..abstract:..- Challenges and prospects for malaria elimination in the Southern Africa regionWilliam J Moss
Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Acta Trop 121:207-11. 2012.... - Validation of oral fluid samples to monitor serological changes to Plasmodium falciparum: an observational study in southern ZambiaAlexis P Chidi
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Malar J 10:162. 2011..The use of oral fluid (OF) samples to detect antibodies to P. falciparum antigens may be a more acceptable strategy to monitor changes in population immunity... - Increased prevalence of the pfdhfr/phdhps quintuple mutant and rapid emergence of pfdhps resistance mutations at codons 581 and 613 in Kisumu, KenyaMaroya D Spalding
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Malar J 9:338. 2010..The baseline study was carried out from 1999-2000, shortly after implementation of SP, and the follow-up study occurred from 2003-2005, during the transition to AL... - A method of active case detection to target reservoirs of asymptomatic malaria and gametocyte carriers in a rural area in Southern Province, ZambiaGillian H Stresman
Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Malar J 9:265. 2010..Therefore, an active case detection system that facilitates detection of asymptomatic parasitaemia and gametocyte carriers was developed and tested in the Macha region in southern Zambia... - Secular trends in pediatric antiretroviral treatment programs in rural and urban Zambia: a retrospective cohort studyCatherine G Sutcliffe
Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
BMC Pediatr 10:54. 2010..We evaluated secular trends in the characteristics and treatment outcomes of children in three pediatric ART clinics in urban and rural areas in Zambia... - Weight and height z-scores improve after initiating ART among HIV-infected children in rural Zambia: a cohort studyCatherine G Sutcliffe
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
BMC Infect Dis 11:54. 2011..This study was undertaken to evaluate growth patterns after ART initiation in a young pediatric population in rural Zambia with a high prevalence of undernutrition... - Barriers to the care of HIV-infected children in rural Zambia: a cross-sectional analysisJanneke H van Dijk
Medical Malaria Institute at Macha, Macha Hospital, Choma, Zambia
BMC Infect Dis 9:169. 2009..The objective of this study was to identify patient characteristics, barriers to care, and treatment responses of HIV-infected children seeking care in rural Zambia... - Immunogenicity of standard-titer measles vaccine in HIV-1-infected and uninfected Zambian children: an observational studyWilliam J Moss
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Infect Dis 196:347-55. 2007.... 
Measles still has a devastating impact in unvaccinated populationsWilliam J Moss
Department of Epidemiology, International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America
PLoS Med 4:e24. 2007
HIV type 1 infection is a risk factor for mortality in hospitalized Zambian children with measlesWilliam J Moss
W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205 2179, USA
Clin Infect Dis 46:523-7. 2008..Measles remains a significant cause of vaccine-preventable mortality in sub-Saharan Africa, yet few studies have investigated risk factors for measles mortality in regions of high human immunodeficiency virus type 1 (HIV-1) prevalence...- Child health in complex emergenciesWilliam J Moss
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Bull World Health Organ 84:58-64. 2006.... - Suppression of human immunodeficiency virus type 1 viral load during acute measlesWilliam J Moss
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD
Pediatr Infect Dis J 28:63-5. 2009.... - Measles control and the prospect of eradicationW J Moss
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore MD, USA
Curr Top Microbiol Immunol 330:173-89. 2009..To achieve the measles mortality reduction goal, continued progress needs to be made in delivering measles vaccines to the world's children... - Incidence and risk factors for Malaria, pneumonia and diarrhea in children under 5 in UNHCR refugee camps: A retrospective studyChristine L Hershey
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Confl Health 5:24. 2011..abstract:.. - Use of remote sensing to identify spatial risk factors for malaria in a region of declining transmission: a cross-sectional and longitudinal community surveyWilliam J Moss
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Malar J 10:163. 2011..The objective of this study was to identify environmental risk factors for malaria transmission using remote sensing technologies to guide malaria control interventions in a region of declining burden of malaria... - Biological feasibility of measles eradicationWilliam J Moss
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
J Infect Dis 204:S47-53. 2011..Measles has been eliminated in large geographical areas, including the Americas. Measles eradication is biologically feasible. The challenges for measles eradication will be logistical, political, and financial... - The burden of malaria in post-emergency refugee sites: A retrospective studyJamie Anderson
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Confl Health 5:17. 2011..abstract:.. - HIV-1 infection as a risk factor for incomplete childhood immunization in ZambiaRosanna W Setse
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
J Trop Pediatr 52:324-8. 2006..Our findings suggest that HIV-1-infected children are at increased risk of vaccine-preventable diseases not only because of impaired immune responses but because of lower rates of vaccine coverage... - Suppression of human immunodeficiency virus replication during acute measlesWilliam J Moss
W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe Street, Rm E5132, Baltimore, MD 21205 2179, USA
J Infect Dis 185:1035-42. 2002..Plasma levels of several potential HIV suppressive factors also were elevated during acute measles. HIV replication is transiently suppressed during acute measles at a time of intense immune activation... - Prospective study of measles in hospitalized, human immunodeficiency virus (HIV)-infected and HIV-uninfected children in ZambiaWilliam J Moss
W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, School of Medicine, Johns Hopkins University, Baltimore, MD 21205 2179, USA
Clin Infect Dis 35:189-96. 2002..HIV-infected children constitute a significant proportion of children hospitalized with measles in countries with high HIV prevalence and are more likely to be younger than the age for routine measles immunization... - Simultaneous infection with Borrelia burgdorferi and human granulocytic ehrlichiosisWilliam J Moss
Department of International Health, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205, USA
Pediatr Infect Dis J 22:91-2. 2003..Early recognition of concurrent Lyme disease and HGE is important because amoxicillin, an antibiotic of choice for young children with early Lyme disease, is ineffective for HGE... - Measles: immune suppression and immune responsesWilliam J Moss
W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD, USA
Int J Biochem Cell Biol 36:1380-5. 2004.... - Differential regulation of interleukin (IL)-4, IL-5, and IL-10 during measles in Zambian childrenWilliam J Moss
W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
J Infect Dis 186:879-87. 2002..Plasma levels of IL-10 were elevated for weeks, potentially contributing to impaired cellular immunity and depressed hypersensitivity responses following measles... - Changing individual-level risk factors for malaria with declining transmission in southern Zambia: a cross-sectional studyCatherine G Sutcliffe
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD, USA
Malar J 10:324. 2011..Changes in individual-level correlates of malaria infection were evaluated over three years in a region of declining malaria transmission in southern Zambia... - MeaslesWilliam J Moss
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
Lancet 379:153-64. 2012..These challenges need to be met to ensure that future generations of children do not die of measles... - Prolonged measles virus shedding in human immunodeficiency virus-infected children, detected by reverse transcriptase-polymerase chain reactionS R Permar
W. Harry Feinstone Department of Molecular Microbiology and Immunology, School of Hygiene and Public Health, Johns Hopkins School of Public Health, Baltimore, MD 21205, USA
J Infect Dis 183:532-8. 2001..HIV-infected children with measles may have a prolonged infectious period that potentially enhances measles virus transmission and hinders measles control... - HIV-1 infection in Zambian children impairs the development and avidity maturation of measles virus-specific immunoglobulin G after vaccination and infectionNitya Nair
W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Infect Dis 200:1031-8. 2009..Antibody avidity may affect neutralizing capacity... - Implications of the human immunodeficiency virus epidemic for control and eradication of measlesW J Moss
Department of Molecular Microbiology and Immunology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
Clin Infect Dis 29:106-12. 1999..Further research on the impact of the HIV epidemic on measles and measles immunization is necessary to guide strategies for the eradication of measles... - Influence of HIV infection on changes in circulating leukocyte counts during measles in Zambian childrenJudith J Ryon
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Infect Dis 192:1950-5. 2005..Therefore, the patterns of changes in leukocyte counts were similar, with little evidence that measles exacerbated HIV-associated lymphocyte abnormalities... - Measles virus inhibits human immunodeficiency virus type 1 reverse transcription and replication by blocking cell-cycle progression of CD4+ T lymphocytesMayra García
W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Gen Virol 89:984-93. 2008..It was concluded that MV inhibits HIV-1 productive replication in part by blocking the proliferation of CD4(+) T lymphocytes... - Slow clearance of measles virus RNA after acute infectionMichaela A Riddell
W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
J Clin Virol 39:312-7. 2007..Measles virus (MV) RNA was detected 1 month after hospitalization with measles in more than half of Zambian children but the duration of detectable RNA was not determined... - Increased thymic output during acute measles virus infectionSallie R Permar
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205-2179, USA
J Virol 77:7872-9. 2003..These findings suggest that a decrease in thymic output is not the cause of the lymphopenia and depressed cellular immunity associated with measles... - Population immunity to measles virus and the effect of HIV-1 infection after a mass measles vaccination campaign in Lusaka, Zambia: a cross-sectional surveySara A Lowther
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Lancet 373:1025-32. 2009..Our aim was to assess population immunity to measles virus after a mass vaccination campaign in a region with high HIV prevalence... - Do children infected with HIV receiving HAART need to be revaccinated?Catherine G Sutcliffe
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD, USA
Lancet Infect Dis 10:630-42. 2010..Vaccination policies and strategies for children infected with HIV on HAART should be developed in regions of high HIV prevalence to ensure adequate individual and population immunity... - Differential effects of priming with DNA vaccines encoding the hemagglutinin and/or fusion proteins on cytokine responses after measles virus challengeFernando P Polack
W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, and Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Infect Dis 187:1794-800. 2003..Responses were modulated when both proteins were used for priming. Therefore, the specific proteins included in a new measles vaccine will affect the type of cytokine response elicited... - Measles vaccinesDiane E Griffin
W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
Front Biosci 13:1352-70. 2008..Several new recombinant vaccines expressing MV proteins have demonstrated induction of protective immunity in macaques and are in various stages of development... - Gene expression changes in peripheral blood mononuclear cells during measles virus infectionMichael J Zilliox
W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Clin Vaccine Immunol 14:918-23. 2007..Most mRNAs had not returned to control values 1 month after discharge, consistent with prolonged immune response abnormalities during measles virus infection... - Hemagglutinin protein is a primary target of the measles virus-specific HLA-A2-restricted CD8+ T cell response during measles and after vaccinationMartin O Ota
W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Infect Dis 195:1799-807. 2007..No single peptide dominated the response. We conclude that H is an important stimulus for CD8+ T cell as well as for antibody responses in HLA-A2-positive individuals... - Global measles eliminationWilliam J Moss
Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Nat Rev Microbiol 4:900-8. 2006..This review discusses the pathogenesis of measles and the likelihood of the worldwide elimination of this disease... - Altered synthesis of interleukin-12 and type 1 and type 2 cytokinesin rhesus macaques during measles and atypical measlesFernando P Polack
W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Hygiene and Public Health, Baltimore, Maryland 21205, USA
J Infect Dis 185:13-9. 2002..In vivo production of IL-12 was decreased during the viremic phase of the illness, and production of IL-4 was increased during and after atypical measles, compared with measles... - Emerging diseases: measlesMartin O Ota
W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
J Neurovirol 11:447-54. 2005..Strategies to sustain high levels of global immunity to measles virus by increasing vaccine coverage with routine and supplementary vaccination campaigns must be supported... - The association of Blastocystis hominis and Endolimax nana with diarrheal stools in Zambian school-age childrenThaddeus K Graczyk
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Parasitol Res 98:38-43. 2005..This survey supports the recent evidence that B. hominis and E. nana infections are associated with deficient sanitation and low hygiene standards and can contribute to diarrhea in children in developing countries... - Functional and phenotypic changes in circulating lymphocytes from hospitalized zambian children with measlesJudith J Ryon
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Clin Diagn Lab Immunol 9:994-1003. 2002.... - In vitro suppression of human immunodeficiency virus type 1 replication by measles virusMayra García
W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
J Virol 79:9197-205. 2005.... - Immune responses to measles and measles vaccine: challenges for measles controlW J Moss
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Viral Immunol 14:297-309. 2001.... - Feasibility of satellite image-based sampling for a health survey among urban townships of Lusaka, ZambiaSara A Lowther
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Trop Med Int Health 14:70-8. 2009.... - Improved measles surveillance in Cameroon reveals two major dynamic patterns of incidenceDerek A T Cummings
Department of International Health, The Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205-5748, USA
Int J Infect Dis 10:148-55. 2006..The availability of a five-year record of measles incidence in Cameroon reveals an interesting dynamic pattern of measles incidence that accounts for the increase in countrywide incidence in 2000-2001... - Survival from 9 months of age among HIV-infected and uninfected Zambian children prior to the availability of antiretroviral therapyCatherine G Sutcliffe
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Clin Infect Dis 47:837-44. 2008..Few prospective studies have measured survival rates among human immunodeficiency virus (HIV)-infected children in sub-Saharan Africa prior to the availability of antiretroviral therapy... - Immunization of children at risk of infection with human immunodeficiency virusWilliam J Moss
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Bull World Health Organ 81:61-70. 2003..Any changes in this policy would have to be carefully examined for a potential negative impact on disease control programmes in many countries... - Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan AfricaCatherine G Sutcliffe
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Lancet Infect Dis 8:477-89. 2008.... - Pilot study of antibiotic cycling in a pediatric intensive care unitWilliam J Moss
Division of Pediatric Infectious Diseases, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Crit Care Med 30:1877-82. 2002..A definitive study will require a randomized and controlled trial of only four pediatric intensive care units over an 18-month period... - Differences in presentation, treatment initiation, and response among children infected with human immunodeficiency virus in urban and rural ZambiaCatherine G Sutcliffe
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Pediatr Infect Dis J 29:849-54. 2010..Few rural ART programs have been evaluated to determine whether these challenges affect care and treatment response... - CD4+ and CD8+ T-lymphocyte subsets in Zambian childrenZaza Ndhlovu
Virology Laboratory, University Teaching Hospital, Lusaka, Zambia
J Trop Pediatr 50:94-7. 2004..Girls between the ages of 12 and 71 months had a higher percentage of CD4+ T-lymphocytes and a higher CD4:CD8 ratio than did boys of a similar age... - Evaluating the impact of the HIV pandemic on measles control and eliminationRita F Helfand
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop A 30, Atlanta, GA 30333, USA
Bull World Health Organ 83:329-37. 2005.... - The influence of HIV-1 exposure and infection on levels of passively acquired antibodies to measles virus in Zambian infantsSusana Scott
London School of Hygiene and Tropical Medicine, London, United Kingdom
Clin Infect Dis 45:1417-24. 2007..Little is known about the influence of human immunodeficiency virus type 1 (HIV-1) infection on levels of prevaccination antibodies to measles virus... - Estimating the force of measles virus infection from hospitalised cases in Lusaka, ZambiaSusana Scott
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Vaccine 23:732-8. 2004..Estimates of the force of infection using routinely available data were consistent with those based upon serological surveys in other sub-Saharan African countries... - Inhibition of HIV-1 replication in human lymphoid tissues ex vivo by measles virusJean-Charles Grivel
Laboratory of Molecular and Cellular Biophysics, National Institute of Child Health and Human Development, Bethesda, Maryland 21205, USA
J Infect Dis 192:71-8. 2005.... - Predicted impact of the HIV-1 epidemic on measles in developing countries: results from a dynamic age-structured modelSusana Scott
London School of Hygiene and Tropical Medicine, London, UK
Int J Epidemiol 37:356-67. 2008..Although measles incidence has been reduced to low levels in many countries, the potential exists for HIV-1 infection to enhance measles virus (MV) transmission and hinder measles control and elimination efforts... - Haemophilus influenzae type b conjugate vaccine use and effectivenessShaun K Morris
Division of Infectious Diseases, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada
Lancet Infect Dis 8:435-43. 2008..Even with new funding support, there are many ongoing challenges and vaccine use remains suboptimal, particularly in developing countries... - Genotyping of measles virus in clinical specimens on the basis of oligonucleotide microarray hybridization patternsAlexander A Neverov
Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, MD 20852 1448, USA
J Clin Microbiol 44:3752-9. 2006..In addition, the microarray demonstrated the ability to identify potential new genotypes of MV based on the similarity of their hybridization patterns with those of known MV genotypes... - The effects of maternal malaria and HIV-1 infection on the effort to eliminate neonatal tetanusWilliam J Moss
J Infect Dis 196:502-4. 2007
Research Grants
- Immune Reconstitution of HIV-1 Infected Zambian Children Initiating AntiretroviraWilliam Moss; Fiscal Year: 2007....
- Immune Reconstitution of HIV-1 Infected Zambian Children Initiating AntiretroviraWilliam Moss; Fiscal Year: 2009....
- Immune Reconstitution of HIV-1 Infected Zambian Children Initiating AntiretroviraWilliam J Moss; Fiscal Year: 2010....