Tammy A Morrish

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres
    Tammy A Morrish
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 0618, USA
    Nature 446:208-12. 2007
  2. pmc Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase
    Huira C Kopera
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109 5618, USA
    Proc Natl Acad Sci U S A 108:20345-50. 2011
  3. ncbi request reprint DNA repair mediated by endonuclease-independent LINE-1 retrotransposition
    Tammy A Morrish
    Department of Human Genetics, University of Michigan Medical School, 1241 E Catherine Street, Ann Arbor, Michigan 48105 0618, USA
    Nat Genet 31:159-65. 2002
  4. pmc Multiple fates of L1 retrotransposition intermediates in cultured human cells
    Nicolas Gilbert
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, 48109 0618, USA
    Mol Cell Biol 25:7780-95. 2005
  5. pmc A comprehensive analysis of recently integrated human Ta L1 elements
    Jeremy S Myers
    Department of Biological Sciences, Biological Computation and Visualization Center, Louisiana State University, 202 Life Sciences Building, Baton Rouge, LA 70803, USA
    Am J Hum Genet 71:312-26. 2002
  6. ncbi request reprint Of man in mice
    Jyoti N Athanikar
    Nat Genet 32:562-3. 2002
  7. pmc Analysis of 5' junctions of human LINE-1 and Alu retrotransposons suggests an alternative model for 5'-end attachment requiring microhomology-mediated end-joining
    Nora Zingler
    Fachgebiet PR2 Retroelemente, Paul Ehrlich Institut, D 63225 Langen, Germany
    Genome Res 15:780-9. 2005

Collaborators

  • John Moran
  • Nicolas Gilbert
  • Jose Luis Garcia-Perez
  • Mark A Batzer
  • Huira C Kopera
  • Nora Zingler
  • Jyoti N Athanikar
  • Jeremy S Myers
  • John B Moldovan
  • Gerald G Schumann
  • Johannes Lower
  • Kay Martin O Hanschmann
  • Thomas Jahns
  • Hans Peter Brose
  • Ute Willhoeft
  • Volker Schoder
  • W Scott Watkins
  • Bethaney J Vincent
  • Lotte Henke
  • Gary D Swergold
  • Jurgen Henke
  • Hunt Udall
  • Gail E Kilroy
  • Lynn B Jorde

Detail Information

Publications7

  1. ncbi request reprint Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres
    Tammy A Morrish
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 0618, USA
    Nature 446:208-12. 2007
    ..Thus, we propose that EN(i) retrotransposition is an ancestral mechanism of RNA-mediated DNA repair associated with non-LTR retrotransposons that may have been used before the acquisition of an endonuclease domain...
  2. pmc Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase
    Huira C Kopera
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109 5618, USA
    Proc Natl Acad Sci U S A 108:20345-50. 2011
    ..Finally, we demonstrate that ORF1p is not strictly required for ENi retrotransposition at dysfunctional telomeres. Thus, these data further highlight similarities between the mechanism of ENi L1 retrotransposition and telomerase...
  3. ncbi request reprint DNA repair mediated by endonuclease-independent LINE-1 retrotransposition
    Tammy A Morrish
    Department of Human Genetics, University of Michigan Medical School, 1241 E Catherine Street, Ann Arbor, Michigan 48105 0618, USA
    Nat Genet 31:159-65. 2002
    ..Thus, our results suggest that LINE-1s can integrate into DNA lesions, resulting in retrotransposon-mediated DNA repair in mammalian cells...
  4. pmc Multiple fates of L1 retrotransposition intermediates in cultured human cells
    Nicolas Gilbert
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, 48109 0618, USA
    Mol Cell Biol 25:7780-95. 2005
    ..Indeed, the initial steps in L1 retrotransposition may define a host/parasite battleground that serves to limit the number of active L1s in the genome...
  5. pmc A comprehensive analysis of recently integrated human Ta L1 elements
    Jeremy S Myers
    Department of Biological Sciences, Biological Computation and Visualization Center, Louisiana State University, 202 Life Sciences Building, Baton Rouge, LA 70803, USA
    Am J Hum Genet 71:312-26. 2002
    ..One hundred fifteen (45%) of the Ta L1 elements were polymorphic with respect to insertion presence or absence and will serve as identical-by-descent markers for the study of human evolution...
  6. ncbi request reprint Of man in mice
    Jyoti N Athanikar
    Nat Genet 32:562-3. 2002
  7. pmc Analysis of 5' junctions of human LINE-1 and Alu retrotransposons suggests an alternative model for 5'-end attachment requiring microhomology-mediated end-joining
    Nora Zingler
    Fachgebiet PR2 Retroelemente, Paul Ehrlich Institut, D 63225 Langen, Germany
    Genome Res 15:780-9. 2005
    ..The results indicate that a cellular nonhomologous DNA end-joining pathway may resolve intermediates from incomplete L1 retrotransposition events and thus lead to 5' truncations...