Yuriko Mori

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors
    Bogdan C Paun
    Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 4:e7715. 2009
  2. ncbi request reprint A genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon cancer
    Yuriko Mori
    Department of Medicine, Division of Gastroenterology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Gastroenterology 131:797-808. 2006
  3. pmc Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning
    Yuriko Mori
    Division of Gastroenterology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, Maryland 21205, USA
    Endocr Relat Cancer 18:465-78. 2011
  4. ncbi request reprint Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk
    Karsten Schulmann
    Division of Gastroenterology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA
    Oncogene 24:4138-48. 2005
  5. pmc The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim
    Takatsugu Kan
    Division of Gastroenterology, Department of Medicine, The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland 21287, USA
    Gastroenterology 136:1689-700. 2009
  6. ncbi request reprint Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning
    Yuriko Mori
    Department of Medicine, Division of Gastroenterology, University of Maryland School of Medicine and Greenebaum Cancer Center and Baltimore Veterans Affairs Hospital, Baltimore, Maryland, USA
    Cancer Res 64:2434-8. 2004
  7. pmc Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells
    Rachana Agarwal
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 4:e8002. 2009
  8. pmc A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus
    Zhe Jin
    Gastroenterology Division, Johns Hopkins University, Baltimore, MD 21287, USA
    Cancer Res 69:4112-5. 2009
  9. doi request reprint Hypermethylation of the AKAP12 promoter is a biomarker of Barrett's-associated esophageal neoplastic progression
    Zhe Jin
    Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, 1503 East Jefferson Street, Baltimore, MD 21231, USA
    Cancer Epidemiol Biomarkers Prev 17:111-7. 2008
  10. ncbi request reprint Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors
    Andreea Olaru
    Department of Medicine, University of Maryland School of Medicine and Baltimore Veteran s Affairs Hospital, Baltimore, Maryland 21201, USA
    Lab Invest 83:1867-71. 2003

Collaborators

Detail Information

Publications46

  1. pmc Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors
    Bogdan C Paun
    Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 4:e7715. 2009
    ..Within this context, we conducted a broad mutational survey of 42 short 3'UTR microsatellites (MSs) in 45 MSI-H colorectal tumors and their corresponding normal colonic mucosae...
  2. ncbi request reprint A genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon cancer
    Yuriko Mori
    Department of Medicine, Division of Gastroenterology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Gastroenterology 131:797-808. 2006
    ..Gene silencing via promoter hypermethylation is a central event in the pathogenesis of cancers. To identify novel methylation targets in colon cancer, we conducted a genome-wide, microarray-based, in silico, and epigenetic search...
  3. pmc Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning
    Yuriko Mori
    Division of Gastroenterology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, Maryland 21205, USA
    Endocr Relat Cancer 18:465-78. 2011
    ..These potential biomarkers significantly discriminate CRC patients from controls. Thus, they merit further evaluation in stool- and circulating DNA-based CRC detection studies...
  4. ncbi request reprint Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk
    Karsten Schulmann
    Division of Gastroenterology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA
    Oncogene 24:4138-48. 2005
    ..These findings have implications regarding risk stratification, early EAC detection, and the appropriate endoscopic surveillance interval for patients with BE...
  5. pmc The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim
    Takatsugu Kan
    Division of Gastroenterology, Department of Medicine, The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland 21287, USA
    Gastroenterology 136:1689-700. 2009
    ..Barrett's esophagus (BE) is a highly premalignant disease that predisposes to the development of esophageal adenocarcinoma (EAC); however, the involvement of microRNAs (miRs) in BE-EAC carcinogenic progression is not known...
  6. ncbi request reprint Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning
    Yuriko Mori
    Department of Medicine, Division of Gastroenterology, University of Maryland School of Medicine and Greenebaum Cancer Center and Baltimore Veterans Affairs Hospital, Baltimore, Maryland, USA
    Cancer Res 64:2434-8. 2004
    ..This methylation screening strategy should identify additional genes inactivated by epigenetic silencing in colorectal and other cancers...
  7. pmc Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells
    Rachana Agarwal
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 4:e8002. 2009
    ..In the present study, we report that claudin-11 (CLDN11) is silenced in gastric cancer via hypermethylation of its promoter region...
  8. pmc A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus
    Zhe Jin
    Gastroenterology Division, Johns Hopkins University, Baltimore, MD 21287, USA
    Cancer Res 69:4112-5. 2009
    ..118, respectively) in all 3 models. A methylation biomarker-based panel to predict neoplastic progression in BE has potential clinical value in improving both the efficiency of surveillance endoscopy and the early detection of neoplasia...
  9. doi request reprint Hypermethylation of the AKAP12 promoter is a biomarker of Barrett's-associated esophageal neoplastic progression
    Zhe Jin
    Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, 1503 East Jefferson Street, Baltimore, MD 21231, USA
    Cancer Epidemiol Biomarkers Prev 17:111-7. 2008
    ....
  10. ncbi request reprint Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors
    Andreea Olaru
    Department of Medicine, University of Maryland School of Medicine and Baltimore Veteran s Affairs Hospital, Baltimore, Maryland 21201, USA
    Lab Invest 83:1867-71. 2003
    ..We conclude that ACTRII is probably involved in both non-MSI-H and MSI-H colorectal carcinogenesis, but more frequently in the latter subgroup...
  11. ncbi request reprint Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression
    James P Hamilton
    Department of Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Clin Cancer Res 12:6637-42. 2006
    ..We also sought to determine whether Reprimo expression could be restored in vitro by the demethylating agent 5-aza-deoxycytidine (5AzaC)...
  12. ncbi request reprint Molecular phenotype of inflammatory bowel disease-associated neoplasms with microsatellite instability
    Karsten Schulmann
    Division of Gastroenterology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Gastroenterology 129:74-85. 2005
    ..We sought to determine the frequency of high-level microsatellite instability (MSI-H) and the mutational and methylation profile of MSI-H IBD-related neoplasms (IBDNs)...
  13. ncbi request reprint MicroRNA-224 negatively regulates p21 expression during late neoplastic progression in inflammatory bowel disease
    Alexandru V Olaru
    Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21231, USA
    Inflamm Bowel Dis 19:471-80. 2013
    ..In the current study, we sought to identify miR dysregulation specific to progression along the normal-inflammation-cancer axis in colonic specimens from patients with IBD...
  14. ncbi request reprint Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis
    Zhe Jin
    Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Cancer 112:43-9. 2008
    ..The aim of the current study was to investigate whether and at what stage promoter hypermethylation of SST is involved in human esophageal carcinogenesis...
  15. ncbi request reprint Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma
    Fumiaki Sato
    Gastroenterology Division, Department of Medicine, University of Maryland School of Medicine and Gastroenterology Service, Baltimore, Maryland 21201, USA
    Cancer Res 62:6820-2. 2002
    ..In conclusion, our data suggest that methylation of HPP1 is a relatively common early event in UC-associated carcinogenesis. HPP1 offers potential as a biomarker for the early detection of cancer or dysplasia in UC...
  16. pmc Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation
    Alexandru V Olaru
    Department of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, Maryland 21231, USA
    Inflamm Bowel Dis 17:221-31. 2011
    ..In the current study we sought to identify specific miR dysregulation along the normal-inflammation-cancer axis...
  17. ncbi request reprint Mutational and LOH analyses of the chromosome 4q region in esophageal adenocarcinoma
    Anca Sterian
    Division of Gastroenterology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Oncology 70:168-72. 2006
    ..Findings from loss of heterozygosity (LOH) studies have suggested that the long arm of chromosome 4 might harbor tumor suppressor genes relevant to esophageal adenocarcinoma...
  18. pmc Generation of small 32P-labeled peptides as a potential approach to colorectal cancer therapy
    John M Abraham
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 3:e2508. 2008
    ..This report proposes the development and use of (32)P-labeled peptides as potential individualized peptide-binding therapies for the treatment of colon adenocarcinoma patients...
  19. pmc MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3
    Florin M Selaru
    Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    Hepatology 49:1595-601. 2009
    ..Conclusions: MiR-21 is overexpressed in human CCAs. Furthermore, miR-21 may be oncogenic, at least in part, by inhibiting PDCD4 and TIMP3. Finally, these data suggest that TIMP3 is a candidate tumor suppressor gene in the biliary tree...
  20. pmc Pituitary tumor-transforming 1 increases cell motility and promotes lymph node metastasis in esophageal squamous cell carcinoma
    Tetsuo Ito
    Division of Gastroenterology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Cancer Res 68:3214-24. 2008
    ..Thus, PTTG1 constitutes a potential biomarker and therapeutic target in ESCCs with lymph node metastases...
  21. ncbi request reprint Polo-like kinase and survivin are esophageal tumor-specific promoters
    Fumiaki Sato
    Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Biochem Biophys Res Commun 342:465-71. 2006
    ..9-fold and 28.5-fold higher, respectively, than in normal lung and renal cells. The promoters of PLK and survivin could be useful tools for developing EC-specific gene therapy vectors...
  22. doi request reprint Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors
    Zhe Jin
    Division of Gastroenterology, Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USA
    Int J Cancer 123:2331-6. 2008
    ..These findings suggest that hypermethylation of CDH13 is a common, tissue-specific event in human EAC, occurs early during BE-associated neoplastic progression, and correlates with known clinical neoplastic progression risk factors...
  23. pmc Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features
    Fumiaki Sato
    Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 3:e1890. 2008
    ..In this study, we developed a 3-tiered risk stratification strategy, based on systematically selected epigenetic and clinical parameters, to improve Barrett's esophagus surveillance efficiency...
  24. ncbi request reprint Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon
    Tong Tong Zou
    Department of Medicine, Division of Gastroenterology and Greenebaum Cancer Center, University of Maryland School of Medicine and Baltimore VA Hospital, Baltimore, Maryland, MD 21201, USA
    Oncogene 21:4855-62. 2002
    ..Our data suggests that a large-scale approach may be undertaken with the purpose of identifying biomarkers relevant to cancer progression...
  25. ncbi request reprint An LOH and mutational investigation of the ST7 gene locus in human esophageal carcinoma
    Suna Wang
    Department of Medicine, Division of Gastroenterology and Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore 21201, USA
    Oncogene 22:467-70. 2003
    ..These data suggest that LOH at 7q31-q35 is involved in the origin or progression of at least a subset of esophageal carcinomas, but that ST7 is not the target gene of this somatic event...
  26. pmc Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer
    Tetsuo Ito
    Division of Gastroenterology, Department of Medicine and Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Int J Cancer 129:2134-46. 2011
    ..8-71.5% of luciferase activity by degrading luciferase mRNA in HSA/c cells. In conclusion, PLK1 is post-transcriptionally regulated by miR-593* and could be a promising molecular target for EC treatment...
  27. pmc Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers
    Alexandru V Olaru
    Department of Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Inflamm Bowel Dis 18:641-8. 2012
    ..We investigated genome-wide CGI methylation in inflammatory bowel disease (IBD)-associated CRCs (IBD-CRCs)...
  28. doi request reprint Aberrant silencing of the endocrine peptide gene tachykinin-1 in gastric cancer
    Stefan David
    Department of Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, 1503 E Jefferson Street Office 108, Baltimore, MA 21287, USA
    Biochem Biophys Res Commun 378:605-9. 2009
    ..5-Aza-2'-deoxycytidine-induced demethylation of the TAC1 promoter resulted in TAC1 mRNA upregulation. Further studies are indicated to elucidate the functional involvement of TAC1 in gastric carcinogenesis...
  29. ncbi request reprint Hypermethylation of HPP1 is associated with hMLH1 hypermethylation in gastric adenocarcinomas
    David M Shibata
    Division of Surgical Oncology, Department of Surgery, University of Maryland School of Medicine, Baltimore 21201, USA
    Cancer Res 62:5637-40. 2002
    ..Moreover, hMLH1 hypermethylation occurs predominantly in the setting of HPP1 hypermethylation. HPP1 hypermethylation may represent an early event in mismatch repair-deficient gastric tumorigenesis...
  30. ncbi request reprint An unsupervised approach to identify molecular phenotypic components influencing breast cancer features
    Florin M Selaru
    Department of Medicine, Division of Gastroenterology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cancer Res 64:1584-8. 2004
    ..Moreover, these findings illustrate the potential of PCs analysis to detect molecular phenotypic bases for relevant clinical or biological features of human tumors in general...
  31. pmc Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas
    Bogdan C Paun
    Division of Gastroenterology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Cancer 116:4495-501. 2010
    ....
  32. ncbi request reprint Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer
    Zhe Jin
    Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Clin Cancer Res 13:6293-300. 2007
    ..Our aim was to investigate whether and at what stage hypermethylation of the tachykinin-1 (TAC1) gene is associated with human esophageal neoplastic transformation...
  33. pmc Novel decapeptides that bind avidly and deliver radioisotope to colon cancer cells
    John M Abraham
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 2:e964. 2007
    ..The rapidly growing field of targeted tumor therapy often utilizes an antibody, sometimes tagged with a tumor-ablating material such as radioisotope, directed against a specific molecule...
  34. ncbi request reprint Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes
    Elena Deacu
    Department of Medicine, Division of Gastroenterology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Cancer Res 64:7690-6. 2004
    ....
  35. ncbi request reprint Esophagin and proliferating cell nuclear antigen (PCNA) are biomarkers of human esophageal neoplastic progression
    Martha C Kimos
    Department of Medicine Gastroenterology Division, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Int J Cancer 111:415-7. 2004
    ..Moreover, this combined staining approach also offers promise for detecting esophageal cancer in early, precancerous stages...
  36. ncbi request reprint Promoter methylation and response to chemotherapy and radiation in esophageal cancer
    James P Hamilton
    Division of Gastroenterology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Clin Gastroenterol Hepatol 4:701-8. 2006
    ..Accordingly, our aim was to find methylation markers that could be used to predict response to chemoradiation...
  37. ncbi request reprint The impact of microsatellite instability on the molecular phenotype of colorectal tumors
    Yuriko Mori
    Department of Medicine, Division of Gastroenterology, University of Maryland School of Medicine, 655 West Baltimore Street, Baltimore, MD 21201, USA
    Cancer Res 63:4577-82. 2003
    ..Thus, both components 3 and 10 reflected different aspects of MSI and helped to establish principal components analysis as a useful tool to identify and characterize distinct biological features of human malignancy...
  38. ncbi request reprint Artificial neural networks distinguish among subtypes of neoplastic colorectal lesions
    Florin M Selaru
    Department of Medicine, Division of Gastroenterology and Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Gastroenterology 122:606-13. 2002
    ..The current study evaluated the ability of artificial neural networks (ANNs) based on complementary DNA (cDNA) microarray data to discriminate between these 2 types of colorectal lesions...
  39. ncbi request reprint Artificial neural networks and gene filtering distinguish between global gene expression profiles of Barrett's esophagus and esophageal cancer
    Yan Xu
    Department of Medicine, Division of Gastroenterology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore VA Hospital, 21201, USA
    Cancer Res 62:3493-7. 2002
    ..Finally, the 160 genes selected by SAM may merit further study as biomarkers of neoplastic progression in the esophagus, as well as in elucidating pathological mechanisms underlying BA and CA...
  40. ncbi request reprint Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers
    Yuriko Mori
    Department of Medicine, University of Maryland School of Medicine, Baltimore Veterans Affairs Hospital, Baltimore, Maryland 21201, USA
    Cancer Res 62:3641-5. 2002
    ..2%), and an endoplasmic reticulum chaperone protein gene SEC63 (37.5%). The mutational spectra for genes with high mutation frequencies were also significantly different between MSI-H gastric and colorectal cancers...
  41. pmc LARP7 is a potential tumor suppressor gene in gastric cancer
    Yulan Cheng
    Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Lab Invest 92:1013-9. 2012
    ..001) relative to control siRNA transfection. Taken together, these findings suggest that LARP7 downregulation occurs early during gastric tumorigenesis and may promote gastric tumorigenesis via p-TEFb dysregulation...
  42. ncbi request reprint Prediction of survival in patients with esophageal carcinoma using artificial neural networks
    Fumiaki Sato
    Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Cancer 103:1596-605. 2005
    ..To create a comprehensive prognostic model for esophageal carcinoma, artificial neural networks (ANNs) were applied to the analysis of a range of patient-related and tumor-related variables...
  43. ncbi request reprint Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated colorectal carcinogenesis
    Fumiaki Sato
    Gastroenterology Division, Department of Medicine, University of Maryland School of Medicine and Gastroenterology Service, Baltimore, Maryland 21201, USA
    Cancer Res 62:1148-51. 2002
    ..p14(ARF) offers potential as a biomarker for the early detection of cancer or dysplasia in UC. Finally, analyses of p14(ARF) methylation in other organs should explore not only frank cancers but other premalignant lesions...
  44. pmc Silencing of miR-370 in human cholangiocarcinoma by allelic loss and interleukin-6 induced maternal to paternal epigenotype switch
    Fangmei An
    Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, United States of America
    PLoS ONE 7:e45606. 2012
    ....
  45. ncbi request reprint Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells
    Xue Yang
    Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Gut 63:881-90. 2014
    ..However, functional lncRNAs and their downstream mechanisms are largely unknown in the molecular pathogenesis of oesophageal adenocarcinoma (EAC) and its progression...
  46. ncbi request reprint RAB32 hypermethylation and microsatellite instability in gastric and endometrial adenocarcinomas
    David Shibata
    Division of Gastrointestinal Oncology, Department of Interdisciplinary Oncology, H Lee Moffitt Cancer Center and Research Institute, University of South Florida College of Medicine, Tampa, FL 33612, USA
    Int J Cancer 119:801-6. 2006
    ..Given its similar involvement in colon cancer, RAB32 inactivation may represent a component of the oncogenic pathway of microsatellite-unstable gastrointestinal adenocarcinomas...