Susumu Mori

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Detection of time-varying structures by large deformation diffeomorphic metric mapping to aid reading of high-resolution CT images of the lung
    Ryo Sakamoto
    Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
    PLoS ONE 9:e85580. 2014
  2. pmc Image corruption detection in diffusion tensor imaging for post-processing and real-time monitoring
    Yue Li
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 8:e49764. 2013
  3. pmc Atlas-based neuroinformatics via MRI: harnessing information from past clinical cases and quantitative image analysis for patient care
    Susumu Mori
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Annu Rev Biomed Eng 15:71-92. 2013
  4. ncbi request reprint Diffusion tensor imaging of the developing mouse brain
    S Mori
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 720 Rutland Ave, Baltimore, MD 21205, USA
    Magn Reson Med 46:18-23. 2001
  5. pmc White matter atlases based on diffusion tensor imaging
    Susumu Mori
    Division of NMR Research, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Curr Opin Neurol 22:362-9. 2009
  6. ncbi request reprint Fiber tract-based atlas of human white matter anatomy
    Setsu Wakana
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 217 Traylor Bldg, 720 Rutland Ave, Baltimore, MD 21205, USA
    Radiology 230:77-87. 2004
  7. ncbi request reprint Principles of diffusion tensor imaging and its applications to basic neuroscience research
    Susumu Mori
    Department of Radiology, Division of NMR, Johns Hopkins University, School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Neuron 51:527-39. 2006
  8. pmc Stereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template
    Susumu Mori
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 40:570-82. 2008
  9. ncbi request reprint Brain white matter anatomy of tumor patients evaluated with diffusion tensor imaging
    Susumu Mori
    Department of Radiology, Johns Hopkins University School of Medicine, F M Kirby Research Center, Kennedy Krieger Institute, Baltimore, MD 21205, USA
    Ann Neurol 51:377-80. 2002
  10. ncbi request reprint Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking
    Susumu Mori
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 47:215-23. 2002

Collaborators

Detail Information

Publications113 found, 100 shown here

  1. pmc Detection of time-varying structures by large deformation diffeomorphic metric mapping to aid reading of high-resolution CT images of the lung
    Ryo Sakamoto
    Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
    PLoS ONE 9:e85580. 2014
    ..To evaluate the accuracy of advanced non-linear registration of serial lung Computed Tomography (CT) images using Large Deformation Diffeomorphic Metric Mapping (LDDMM)...
  2. pmc Image corruption detection in diffusion tensor imaging for post-processing and real-time monitoring
    Yue Li
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 8:e49764. 2013
    ..The real-time monitoring, based on cISID and followed by post-processing, fitting-based outlier rejection, could provide a robust environment for routine DTI studies. ..
  3. pmc Atlas-based neuroinformatics via MRI: harnessing information from past clinical cases and quantitative image analysis for patient care
    Susumu Mori
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Annu Rev Biomed Eng 15:71-92. 2013
    ..The review covers the current technology, preliminary data, and future directions of this field. ..
  4. ncbi request reprint Diffusion tensor imaging of the developing mouse brain
    S Mori
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 720 Rutland Ave, Baltimore, MD 21205, USA
    Magn Reson Med 46:18-23. 2001
    ..This ability to detect changes in the organization of the brain during development will greatly enhance morphological studies of transgenic and knockout models of cortical dysfunction. Magn Reson Med 46:18-23, 2001...
  5. pmc White matter atlases based on diffusion tensor imaging
    Susumu Mori
    Division of NMR Research, The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Curr Opin Neurol 22:362-9. 2009
    ..This review will provide an overview of the recent advancements in DTI-based studies and new image analysis tools...
  6. ncbi request reprint Fiber tract-based atlas of human white matter anatomy
    Setsu Wakana
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 217 Traylor Bldg, 720 Rutland Ave, Baltimore, MD 21205, USA
    Radiology 230:77-87. 2004
    ..which anatomic structures can be identified on diffusion tensor images and (b). where these anatomic units are located at each section level and orientation. The atlas may prove useful for educational and clinical purposes...
  7. ncbi request reprint Principles of diffusion tensor imaging and its applications to basic neuroscience research
    Susumu Mori
    Department of Radiology, Division of NMR, Johns Hopkins University, School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Neuron 51:527-39. 2006
    ..The strengths and limitations of DTI and key areas for future research and development are also discussed...
  8. pmc Stereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template
    Susumu Mori
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 40:570-82. 2008
    ..The atlases are freely available and believed to be a useful resource as a target template and for automated parcellation methods...
  9. ncbi request reprint Brain white matter anatomy of tumor patients evaluated with diffusion tensor imaging
    Susumu Mori
    Department of Radiology, Johns Hopkins University School of Medicine, F M Kirby Research Center, Kennedy Krieger Institute, Baltimore, MD 21205, USA
    Ann Neurol 51:377-80. 2002
    ..DTI provides new information regarding the detailed relationship between tumor growth and nearby white matter tracts, which may be useful for preoperative planning...
  10. ncbi request reprint Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking
    Susumu Mori
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 47:215-23. 2002
    ..As a first illustration of this technical capability, a reduction in brain connectivity in a patient with a childhood neurodegenerative disease (X-linked adrenoleukodystrophy) was demonstrated...
  11. ncbi request reprint Fiber tracking: principles and strategies - a technical review
    Susumu Mori
    Johns Hopkins University School of Medicine, Department of Radiology and Radiological Science, Baltimore, MD 21205, USA
    NMR Biomed 15:468-80. 2002
    ..Special attention is paid to situations where complications may arise, and possible solutions are reviewed. Validation issues and potential future directions and improvements are also discussed...
  12. pmc Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantification
    Kegang Hua
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 39:336-47. 2008
    ..Excellent correlation was found between the automated and the individual tractography-based results. This tool allows efficient initial screening of the status of multiple white matter tracts...
  13. pmc Atlas-based whole brain white matter analysis using large deformation diffeomorphic metric mapping: application to normal elderly and Alzheimer's disease participants
    Kenichi Oishi
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 46:486-99. 2009
    ..81 (controls) and 0.82 (patients), suggesting "almost perfect" agreement. A power analysis suggested that the proposed method is suitable for detecting FA and size abnormalities of the white matter in clinical studies...
  14. pmc Landmark-referenced voxel-based analysis of diffusion tensor images of the brainstem white matter tracts: application in patients with middle cerebral artery stroke
    Weihong Zhang
    FM Kirby Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD 21205, USA
    Neuroimage 44:906-13. 2009
    ..We believe that this tool is useful for regional brain normalization of patients with severe anatomical alterations, such as stroke, brain tumor, and lobectomy, for whom standard automated normalization tools may not work properly...
  15. pmc Mapping of functional areas in the human cortex based on connectivity through association fibers
    Kegang Hua
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Cereb Cortex 19:1889-95. 2009
    ..The proposed approach can potentially be used for quantitative assessment of the effect of white matter abnormalities on associated cortical regions...
  16. pmc Atlas-based analysis of neurodevelopment from infancy to adulthood using diffusion tensor imaging and applications for automated abnormality detection
    Andreia V Faria
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neuroimage 52:415-28. 2010
    ..As a demonstration of future application studies, the brainstem anatomy of cerebral palsy patients was evaluated and the altered anatomy was delineated...
  17. ncbi request reprint Tractography for arteriovenous malformations near the sensorimotor cortices
    Kei Yamada
    Department of Radiology Kyoto Prefectural University of Medicine, Kyoto, Japan
    AJNR Am J Neuroradiol 26:598-602. 2005
    ..The relationship between the sensorimotor tracts and the AVM was well demonstrated in all patients. Tractography was also helpful in identifying the location of the motor cortex in some of the cases...
  18. ncbi request reprint Magnetic resonance diffusion tensor microimaging reveals a role for Bcl-x in brain development and homeostasis
    Jiangyang Zhang
    Department of Radiology, Division of Nuclear Magnetic Resonance Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 25:1881-8. 2005
    ..Thus, this technique serves as a powerful tool to efficiently localize temporal and spatial manifestation of morphological phenotype...
  19. pmc Fornix integrity and hippocampal volume predict memory decline and progression to Alzheimer's disease
    Michelle M Mielke
    Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Alzheimers Dement 8:105-13. 2012
    ....
  20. ncbi request reprint DTI tractography based parcellation of white matter: application to the mid-sagittal morphology of corpus callosum
    Hao Huang
    Johns Hopkins University School of Medicine, Department of Radiology, Division of MRI Research, Baltimore, MD 21205, USA
    Neuroimage 26:195-205. 2005
    ..This approach provides a new tool to investigate callosal morphology and functional relationships...
  21. pmc Diffusion tensor imaging to assess axonal regeneration in peripheral nerves
    Helmar C Lehmann
    Department of Neurology, Johns Hopkins University, Baltimore, MD, USA
    Exp Neurol 223:238-44. 2010
    ..These studies suggest that DTI is a sensitive measure of axon regeneration in mouse models and provide basis for further development of imaging technology for application to living animals and humans...
  22. pmc Unique patterns of diffusion directionality in rat brain tumors revealed by high-resolution diffusion tensor MRI
    Jiangyang Zhang
    Division of MR Research, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 58:454-62. 2007
    ..High-resolution ex vivo imaging and histology confirmed the in vivo findings. These distinct patterns, undetectable with conventional MRI, may reflect tumor organization and growth patterns at the cellular level...
  23. pmc Delayed neural network degeneration after neonatal hypoxia-ischemia
    Brian S Stone
    Department of Pediatrics, Eudowood Neonatal Pulmonary Division, Neonatal Research Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Ann Neurol 64:535-46. 2008
    ....
  24. pmc Effects of signal-to-noise ratio on the accuracy and reproducibility of diffusion tensor imaging-derived fractional anisotropy, mean diffusivity, and principal eigenvector measurements at 1.5 T
    Jonathan A D Farrell
    F M Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA
    J Magn Reson Imaging 26:756-67. 2007
    ....
  25. ncbi request reprint Diffusion tensor-based imaging reveals occult abnormalities in adrenomyeloneuropathy
    Prachi Dubey
    Department of Neurogenetics and Functional Magnetic Resonance Imaging Kirby Center, Kennedy Krieger Institute, Baltimore, MD 21205, USA
    Ann Neurol 58:758-66. 2005
    ..Accompanying abnormalities in genu of corpus callosum indicate that the disease pathology in pure AMN may not be limited to spinal cord long tracts alone, although the involvement of the latter is most prominent and severe...
  26. ncbi request reprint Mapping postnatal mouse brain development with diffusion tensor microimaging
    Jiangyang Zhang
    Johns Hopkins University, School of Medicine, Department of Radiology, Division of NMR Research, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Neuroimage 26:1042-51. 2005
    ..The results demonstrate the use of these techniques to three-dimensionally and quantitatively characterize brain growth...
  27. ncbi request reprint Characterization of mouse brain and its development using diffusion tensor imaging and computational techniques
    Jiangyang Zhang
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD21205, USA
    Conf Proc IEEE Eng Med Biol Soc 1:2252-5. 2006
    ..To characterize the spatial and temporal patterns of mouse brain development, we applied landmark based computational techniques to analyze the database...
  28. pmc Atlas-guided tract reconstruction for automated and comprehensive examination of the white matter anatomy
    Yajing Zhang
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 52:1289-301. 2010
    ..Probabilistic maps of the 59 tract trajectories were created from the normal subjects and were incorporated into our image analysis tool for automated tract-specific quantification...
  29. pmc Multi-contrast large deformation diffeomorphic metric mapping for diffusion tensor imaging
    Can Ceritoglu
    The Center for Imaging Science, Johns Hopkins University, Baltimore, MD 21205, USA
    Neuroimage 47:618-27. 2009
    ..To improve the accuracy level, cascading and multi-contrast approaches were developed. The accuracy level for the white matter was 1.88+/-0.55 and 2.19+/-0.84 mm for the measured locations in the controls and patients, respectively...
  30. pmc Distinct mechanisms and timing of language recovery after stroke
    Samson Jarso
    a Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MA, USA
    Cogn Neuropsychol 30:454-75. 2013
    ..These cases illustrate different mechanisms of aphasia recovery or illustrate that reorganization of language acutely depends on individual variables in addition to size and site of stroke. ..
  31. ncbi request reprint Stroke patients' evolving symptoms assessed by tractography
    Kei Yamada
    Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto City, Kyoto, Japan
    J Magn Reson Imaging 20:923-9. 2004
    ..To test the hypothesis that an interval evolution in the location of the depicted sensorimotor tract relative to the infarct (the "tract-infarct relationship") may be related to stroke victims' symptom progression...
  32. ncbi request reprint Fiber-tracking method reveals sensorimotor pathway involvement in stroke patients
    Kei Yamada
    Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Stroke 34:E159-62. 2003
    ..We tested the feasibility of a new MRI technique that provides visualization of the sensorimotor tracts in vivo in a group of stroke victims...
  33. doi request reprint Diffusion tensor MRI of the kidney at 3.0 and 1.5 Tesla
    Aki Kido
    Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Shogoin, Sakyo ku, Kyoto, Japan
    Acta Radiol 51:1059-63. 2010
    ..Diffusion tensor imaging (DTI) at 3 T provides information on the microstructure and pathophysiology of tissues that is not available from conventional imaging with an advantage of high signal to noise ratio (SNR)...
  34. pmc Anatomical characterization of athetotic and spastic cerebral palsy using an atlas-based analysis
    Shoko Yoshida
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Magn Reson Imaging 38:288-98. 2013
    ....
  35. pmc Diffusion tensor magnetic resonance imaging of Wallerian degeneration in rat spinal cord after dorsal root axotomy
    Jiangyang Zhang
    Russel H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 29:3160-71. 2009
    ..These data suggest that there is an early imaging signature associated with axon transections that could be used in a variety of neurological disease processes...
  36. pmc Reproducibility of quantitative tractography methods applied to cerebral white matter
    Setsu Wakana
    F M Kirby Center for Functional Brain Imaging, Kennedy Krieger Institute Baltimore, MD 21205, USA
    Neuroimage 36:630-44. 2007
    ..Hemispheric asymmetry was observed for the size of white matter tracts projecting to the temporal lobe. This protocol provides guidelines for reproducible DTI-based tract-specific quantification...
  37. pmc Anatomical characterization of human fetal brain development with diffusion tensor magnetic resonance imaging
    Hao Huang
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 29:4263-73. 2009
    ..The developing fetal brain DTI database presented can be used for education, as an anatomical research reference, and for data registration...
  38. ncbi request reprint Spatial normalization of diffusion tensor fields
    Dongrong Xu
    Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Magn Reson Med 50:175-82. 2003
    ..Simulated experiments using this methodology are also described...
  39. ncbi request reprint White and gray matter development in human fetal, newborn and pediatric brains
    Hao Huang
    Department of Radiology, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Neuroimage 33:27-38. 2006
    ..The resultant DTMRI-based 3D human brain data will be a valuable resource for human brain developmental study and will provide reference standards for diagnostic radiology of premature newborns...
  40. pmc Depressive symptoms in prodromal Huntington's Disease correlate with Stroop-interference related functional connectivity in the ventromedial prefrontal cortex
    Paul G Unschuld
    Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Psychiatry Res 203:166-74. 2012
    ..These findings suggest that depressive symptoms in prodromal HD subjects may reflect altered functional brain network activity in the context of early HD-related brain alterations...
  41. pmc Correction of B0 susceptibility induced distortion in diffusion-weighted images using large-deformation diffeomorphic metric mapping
    Hao Huang
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Magn Reson Imaging 26:1294-302. 2008
    ..This postprocessing method is especially useful for correcting existent DTI data without phase maps...
  42. pmc Spatiotemporal maturation patterns of murine brain quantified by diffusion tensor MRI and deformation-based morphometry
    Ragini Verma
    Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, 3600 Market Street, Suite 380, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 102:6978-83. 2005
    ..This analysis provides a framework for quantifying normative maturation patterns against which phenotypes of mice of different genetic and environmental backgrounds can be contrasted...
  43. ncbi request reprint Diffusion tensor magnetic resonance imaging and tract-tracing analysis of Probst bundle structure in Netrin1- and DCC-deficient mice
    Tianbo Ren
    Department of Anatomy and Neurobiology and The Program in Neuroscience, The University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Neurosci 27:10345-9. 2007
    ..In these regions, a higher-resolution approach such as tract tracing is required. We conclude that in DCC and Netrin1 mutant mice, guidance mechanisms remain in the dorsal part of the tract but are lost ventrally...
  44. pmc Multiparametric magnetic resonance imaging analysis of the corticospinal tract in multiple sclerosis
    Daniel S Reich
    Department of Neurology, Johns Hopkins University, 600 N Wolfe St, Baltimore, MD 21287, USA
    Neuroimage 38:271-9. 2007
    ..To do so, we develop an intuitive method for creating and displaying spatially normalized tract-specific imaging data...
  45. ncbi request reprint A framework for callosal fiber distribution analysis
    Dongrong Xu
    Center for Biomedical Image Computing, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Neuroimage 17:1131-43. 2002
    ..The proposed approach combines methodologies for fiber tracking and spatial normalization and is applied on diffusion tensor images and standard magnetic resonance images...
  46. pmc Cortico-cortical, cortico-striatal, and cortico-thalamic white matter fiber tracts generated in the macaque brain via dynamic programming
    J Tilak Ratnanather
    1 Center for Imaging Science, Johns Hopkins University, Baltimore, Maryland
    Brain Connect 3:475-90. 2013
    ..DP is able to generate known pathways, including crossing and kissing tracts. Thus, DP has the potential to enhance neuroimaging studies of cortical connectivity...
  47. pmc An MRI-based atlas and database of the developing mouse brain
    Nelson Chuang
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 54:80-9. 2011
    ..The atlas and database enhance our ability to examine the neuroanatomy in normal or genetically engineered mouse strains and mouse models of neurological diseases...
  48. pmc Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging
    Manisha Aggarwal
    Division of NMR Research, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 60:2086-95. 2012
    ..The findings of this report can be used for future testing and comparison of potential therapeutics in mouse models of HD...
  49. pmc Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter
    Kenichi Oishi
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 43:447-57. 2008
    ..We anticipate that this atlas will be useful resource for atlas-based white matter anatomical studies...
  50. ncbi request reprint Detection of amyloid plaques in mouse models of Alzheimer's disease by magnetic resonance imaging
    Jiangyang Zhang
    Department of Radiology, Division of NMR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 51:452-7. 2004
    ..It enabled us to study the distribution of plaques in the entire brain in 3D. The results of this study suggest that this method may be useful for assessing treatment efficacy in mouse models of Alzheimer's disease (AD)...
  51. ncbi request reprint Diffusion tensor MR imaging of the brain and white matter tractography
    Elias R Melhem
    Department of Radiology and Radiological Sciences, The Johns Hopkins Medical Institutions, 600 N Wolfe St, Baltimore, MD 21287 2182, USA
    AJR Am J Roentgenol 178:3-16. 2002
  52. ncbi request reprint Diffusion tensor brain imaging and tractography
    Ryuta Ito
    Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan
    Neuroimaging Clin N Am 12:1-19. 2002
    ....
  53. doi request reprint Anatomical characterization of athetotic and spastic cerebral palsy using an atlas-based analysis
    Shoko Yoshida
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Magn Reson Imaging 38:spcone. 2013
    ....
  54. pmc Atlas-based analysis of resting-state functional connectivity: evaluation for reproducibility and multi-modal anatomy-function correlation studies
    Andreia V Faria
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 61:613-21. 2012
    ..As an example of the cross-modality analysis, correlation with anatomical connectivity is also examined...
  55. pmc DTI analyses and clinical applications in Alzheimer's disease
    Kenichi Oishi
    The Russell H Morgan Department of Radiology and Radiological Science, School of Medicine, The Johns Hopkins University, Baltimore, MD 21205, USA
    J Alzheimers Dis 26:287-96. 2011
    ..Application of these findings in clinical practice remains to be demonstrated...
  56. ncbi request reprint Macroscopic orientation component analysis of brain white matter and thalamus based on diffusion tensor imaging
    Setsu Wakana
    Johns Hopkins University School of Medicine, Department of Radiology and Radiological Science, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Magn Reson Med 53:649-57. 2005
    ..Based on the results from these preliminary data sets, this new analysis technique is expected to be an effective tool for macroscopic white matter characterization...
  57. pmc Automated fiber tracking of human brain white matter using diffusion tensor imaging
    Weihong Zhang
    The Russell H Morgan Department of Radiology and Radiological Science, Division of MRI Research, Neurosection, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 42:771-7. 2008
    ..8) and remained high up to 4-5 mm of the linear transformation errors. As a first example, the automated approach was applied to brain tumor patients and strategies to cope with severe anatomical abnormalities are discussed...
  58. pmc Quantitative evaluation of brain development using anatomical MRI and diffusion tensor imaging
    Kenichi Oishi
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA Electronic address
    Int J Dev Neurosci 31:512-24. 2013
    ..Future directions include multimodal image analysis and personalization for clinical application...
  59. pmc Longitudinal, region-specific course of diffusion tensor imaging measures in mild cognitive impairment and Alzheimer's disease
    Milap A Nowrangi
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine and Johns Hopkins Bayview Medical Center, Baltimore, MD, USA
    Alzheimers Dement 9:519-28. 2013
    ..There have not been many studies establishing its longitudinal utility...
  60. pmc Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease
    Mali Jiang
    Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Hum Mol Genet 22:2462-70. 2013
    ..These data highlight consideration of TrkB as a therapeutic target in HD and suggest that small-molecule TrkB agonists that penetrate the brain have high potential to be further tested in clinical trials of HD...
  61. pmc Diffeomorphic brain mapping based on T1-weighted images: improvement of registration accuracy by multichannel mapping
    Aigerim Djamanakova
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Magn Reson Imaging 37:76-84. 2013
    ..To improve image registration accuracy in neurodegenerative populations...
  62. pmc Superficially located white matter structures commonly seen in the human and the macaque brain with diffusion tensor imaging
    Kenichi Oishi
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Brain Connect 1:37-47. 2011
    ..The delineation of these species-conserved white matter structures may provide new options for understanding brain anatomy and function...
  63. pmc Quantitative analysis of gray and white matter in Williams syndrome
    Andreia Vasconcellos Faria
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Neuroreport 23:283-9. 2012
    ..These findings may be linked to the uneven cognitive profile evident in Williams syndrome...
  64. pmc Quantification of brain maturation and growth patterns in C57BL/6J mice via computational neuroanatomy of diffusion tensor images
    Sajjad Baloch
    Department of Radiology, University of Pennsylvania, PA 19104, USA
    Cereb Cortex 19:675-87. 2009
    ..Fiber maturation reaches steady state in about 10 days for the cortex, to 30-40 days for the corpus callosum, the hippocampus, and the internal and external capsules...
  65. ncbi request reprint Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling
    Yanshu Wang
    Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 26:355-64. 2006
    ..This work demonstrates the usefulness of muDTI and genetically directed neuronal labeling for the analysis of nervous system defects in the mouse...
  66. pmc Multi-modal MRI analysis with disease-specific spatial filtering: initial testing to predict mild cognitive impairment patients who convert to Alzheimer's disease
    Kenichi Oishi
    Department of Radiology, Johns Hopkins University Baltimore, MD, USA
    Front Neurol 2:54. 2011
    ..Conclusion: The multi-modal approach has the potential to increase the value of MRI in predicting conversion from aMCI to AD...
  67. pmc Quantitative analysis of brain pathology based on MRI and brain atlases--applications for cerebral palsy
    Andreia V Faria
    The Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 54:1854-61. 2011
    ..We illustrate some potential applications for individual characterization and group comparison. This technique also provides a framework for determining the impact of various neuroanatomic features on brain functions...
  68. pmc Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model
    Yong Cheng
    Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Neuroimage 56:1027-34. 2011
    ..Our present studies provide the first evidence that longitudinal structural MRI measures can detect the therapeutic effect in HD mice, suggesting that such measures in brain could be valuable biomarkers in HD clinical trials...
  69. pmc Magnetic resonance imaging of mouse skeletal muscle to measure denervation atrophy
    Jiangyang Zhang
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Exp Neurol 212:448-57. 2008
    ..We propose that MRI of skeletal muscle is a sensitive surrogate outcome measure of denervation atrophy in animal models of neuromuscular disorders, with potential applicability in preclinical therapeutic screening studies in rodents...
  70. ncbi request reprint Image contrast using the secondary and tertiary eigenvectors in diffusion tensor imaging
    Jiangyang Zhang
    Division of NMR Research, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 55:439-49. 2006
    ..Our results suggest that when these contrasts are combined with a priori anatomical knowledge, they reveal neuroanatomical information that is useful for tissue segmentation and diagnosis of white matter lesions...
  71. ncbi request reprint High-resolution diffusion tensor imaging of the brain stem at 3 T
    Lidia M Nagae-Poetscher
    Russell H Morgan Department of Radiology and Radiological Science and the Kennedy Krieger Institute, F M Kirby Research Center for Functional Brain Imaging, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    AJNR Am J Neuroradiol 25:1325-30. 2004
    ..Various structures in the brain stem, such as the inferior olivary nuclei, deep cerebellar nuclei, some cranial nerves, and white matter tracts were identified, which have been difficult to appreciate by conventional MR techniques...
  72. ncbi request reprint Analysis of noise effects on DTI-based tractography using the brute-force and multi-ROI approach
    Hao Huang
    Department of Radiology, Division of MRI Research, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Magn Reson Med 52:559-65. 2004
    ..The results confirmed the hypothesis that one can increase the validity of DTI-based tractography by adopting the BF and multi-ROI approach, with respect to the simple one-ROI approach...
  73. ncbi request reprint Sensorimotor function and axonal integrity in adrenomyeloneuropathy
    Kathleen M Zackowski
    Kennedy Krieger Institute, The Johns Hopkins University Baltimore, MD 21205, USA
    Arch Neurol 63:74-80. 2006
    ..Gait abnormalities and sensorimotor disturbances are principal defects in adrenomyeloneuropathy (AMN). However, to our knowledge, their association with overall impairment and neuroanatomical changes has not been defined...
  74. ncbi request reprint Imaging, anatomical, and molecular analysis of callosal formation in the developing human fetal brain
    Tianbo Ren
    Department of Anatomy and Neurobiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Anat Rec A Discov Mol Cell Evol Biol 288:191-204. 2006
    ..Thus, the mouse is an excellent model system for studying normal and pathological commissural formation in human brain development...
  75. pmc Diffusion tensor imaging of neuropsychiatric symptoms in mild cognitive impairment and Alzheimer's dementia
    Sarah K Tighe
    Johns Hopkins University School of Medicine, Department of Psychiatry, Baltimore, MD, USA
    J Neuropsychiatry Clin Neurosci 24:484-8. 2012
    ..Further imaging studies are necessary to elucidate the role of the AC in the pathophysiology of neuropsychiatric symptoms in AD and MCI...
  76. pmc Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin
    Elaine Waldron-Roby
    Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosci 32:183-93. 2012
    ....
  77. pmc Evidence of slow maturation of the superior longitudinal fasciculus in early childhood by diffusion tensor imaging
    Jiangyang Zhang
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA, and Diagnostic Radiology Unit, Saint Luc University Hospital, Brussels, Belgium
    Neuroimage 38:239-47. 2007
    ..The result is attributed to slow axonal and/or myelin maturation of this tract, which is believed to be involved in language functions...
  78. ncbi request reprint DtiStudio: resource program for diffusion tensor computation and fiber bundle tracking
    Hangyi Jiang
    Department of Radiology, Johns Hopkins University, School of Medicine, 217 Traylor Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Comput Methods Programs Biomed 81:106-16. 2006
    ..The program is developed using C++ and OpenGL on a Windows platform...
  79. pmc Automated vs. conventional tractography in multiple sclerosis: variability and correlation with disability
    Daniel S Reich
    Department of Radiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Neuroimage 49:3047-56. 2010
    ..In the optic tract, the automated method failed. With judicious application, therefore, the automated method may be useful for studies that investigate the relationship between imaging findings and clinical outcomes in disease...
  80. ncbi request reprint Three-dimensional diffusion tensor magnetic resonance microimaging of adult mouse brain and hippocampus
    Jiangyang Zhang
    Department of Radiology, Division of MRI Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Neuroimage 15:892-901. 2002
    ..Identification of these structures allowed reconstruction of their 3-D volume. Thus, high-resolution DTI has excellent potential as a tool for 3-D characterization of murine brains...
  81. ncbi request reprint Effects of diffusion weighting schemes on the reproducibility of DTI-derived fractional anisotropy, mean diffusivity, and principal eigenvector measurements at 1.5T
    Bennett A Landman
    Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 36:1123-38. 2007
    ..This result suggests that typical clinical studies, which use similar protocols but different well-balanced DW schemes, are readily comparable within the experimental precision...
  82. pmc Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images
    Jiangyang Zhang
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 49:2340-51. 2010
    ..This is the first report of longitudinal characterization of brain atrophy in a mouse model of Huntington's disease by using automatic morphological analysis...
  83. ncbi request reprint Proton MR spectroscopic and diffusion tensor brain MR imaging in X-linked adrenoleukodystrophy: initial experience
    Florian S Eichler
    F M Kirby Research Center for Functional Brain Imaging, Johns Hopkins University, Baltimore, MD, USA
    Radiology 225:245-52. 2002
    ..To compare conventional magnetic resonance (MR) imaging, proton MR spectroscopic imaging, and diffusion tensor (DT) MR imaging findings in patients with X chromosome-linked adrenoleukodystrophy (X-ALD)...
  84. ncbi request reprint High resolution diffusion tensor imaging of axonal damage in focal inflammatory and demyelinating lesions in rat spinal cord
    Cynthia A Deboy
    Department of Neurology, Johns Hopkins University, School of Medicine, USA
    Brain 130:2199-210. 2007
    ..These data suggest that high resolution DTI may be a more sensitive method than conventional imaging for detecting axonal damage at sites distant from inflammation...
  85. ncbi request reprint Three-dimensional anatomical characterization of the developing mouse brain by diffusion tensor microimaging
    Jiangyang Zhang
    Johns Hopkins University School of Medicine, Department of Radiology, Division of NMR Research, 720 Rutland Ave, Baltimore, MD 21205, USA
    Neuroimage 20:1639-48. 2003
    ..The technique was applied to the study of the Netrin-1 mutant, allowing verification of its anatomical phenotype...
  86. pmc Diffusion tensor imaging at low SNR: nonmonotonic behaviors of tensor contrasts
    Bennett A Landman
    Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Magn Reson Imaging 26:790-800. 2008
    ..Comparative results are shown in both graphical and tabular forms, so that decisions about suitable acquisition protocols and processing methods can be made on a case-by-case basis without exhaustive experimentation...
  87. ncbi request reprint Passive immunization with anti-ganglioside antibodies directly inhibits axon regeneration in an animal model
    Helmar C Lehmann
    Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    J Neurosci 27:27-34. 2007
    ....
  88. ncbi request reprint Mechanism of magnetization transfer during on-resonance water saturation. A new approach to detect mobile proteins, peptides, and lipids
    Peter C M van Zijl
    Division of MRI Research, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 49:440-9. 2003
    ....
  89. doi request reprint Magnetic resonance imaging-based mouse brain atlas and its applications
    Manisha Aggarwal
    The Russell H Morgan Department of Radiology and Radiological Science, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 711:251-70. 2011
    ..The chapter then demonstrates several applications of MRI-based mouse brain atlases in anatomical phenotyping and guiding stereotaxic operations...
  90. pmc Multi-contrast human neonatal brain atlas: application to normal neonate development analysis
    Kenichi Oishi
    Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neuroimage 56:8-20. 2011
    ....
  91. doi request reprint Reduced fractional anisotropy in early-stage cerebellar variant of multiple system atrophy
    Kenichi Oishi
    Division of Neurology, Kobe University Hospital, Kobe, Japan
    J Neuroimaging 19:127-31. 2009
    ..The sensitivity of detecting early-stage MSA-C and the time course of the FA reduction are also unknown. The purpose was to address these issues to determine the diagnostic value of FA for early diagnosis...
  92. pmc Sensorimotor function and sensorimotor tracts after hemispherectomy
    Julia T Choi
    The Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA
    Neuropsychologia 48:1192-9. 2010
    ..Age at surgery predicted anatomical status of brainstem sensorimotor tracts. In sum, we found that age at surgery influences anatomical changes in brainstem motor pathways, and may also relate to sensorimotor recovery patterns...
  93. pmc Three-dimensional diffusion tensor microimaging for anatomical characterization of the mouse brain
    Manisha Aggarwal
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 64:249-61. 2010
    ....
  94. ncbi request reprint High-resolution isotropic 3D diffusion tensor imaging of the human brain
    Xavier Golay
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 47:837-43. 2002
    ..g., brain pulsations) with respect to cardiac-gated multislice acquisition are demonstrated. The advantages and weaknesses of this approach are discussed...
  95. ncbi request reprint Holoprosencephaly in children: diffusion tensor MR imaging of white matter tracts of the brainstem--initial experience
    Sait Albayram
    Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Radiology 223:645-51. 2002
    ....
  96. pmc Diffusion tensor imaging in children and adolescents: reproducibility, hemispheric, and age-related differences
    David Bonekamp
    The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Neuroimage 34:733-42. 2007
    ..Our results show that the evaluated DTI protocol is suitable for clinical application in pediatric population...
  97. ncbi request reprint Origin and minimization of residual motion-related artifacts in navigator-corrected segmented diffusion-weighted EPI of the human brain
    Hangyi Jiang
    Department of Radiology, Division of MRI Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 47:818-22. 2002
    ..In addition it is shown that the effects of involuntary motion can be removed by swapping k-space data between redundant datasets...
  98. ncbi request reprint Magnetic resonance microscopy of mouse brain development
    Susumu Mori
    Russell H Morgan Department of Radiology and Radiological Science, Kennedy Krieger Institute, Baltimore, MD, USA
    Methods Mol Med 124:129-47. 2006
    ..In this article, the future potential of magnetic resonance (MR) microimaging is discussed, with special emphasis on diffusion tensor microimaging as an effective contrast mechanism for the developing central nervous system...
  99. ncbi request reprint Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery
    Shozo Goto
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University Schools of Medicine, Baltimore, MD 21287, USA
    Stroke 33:1101-6. 2002
    ..PARP-/- mice were also treated with viral transfection of wild-type PARP-1 to determine whether protection from MCA occlusion is lost with restoration of the gene product...
  100. ncbi request reprint Regional white matter change in pre-symptomatic Huntington's disease: a diffusion tensor imaging study
    Sarah A J Reading
    Division of Psychiatric Neuroimaging, Department of Psychiatry, The Johns Hopkins University, Phipps 313, Baltimore, MD 21287, USA
    Psychiatry Res 140:55-62. 2005
    ..Our results indicate that, before the onset of manifest HD, there are regional decreases in fractional anisotropy, indicating early white matter disorganization...
  101. ncbi request reprint Pediatric diffusion tensor imaging: normal database and observation of the white matter maturation in early childhood
    Laurent Hermoye
    Diagnostic Radiology Unit, Saint Luc University Hospital, Universite Catholique de Louvain, Brussels, Belgium
    Neuroimage 29:493-504. 2006
    ..The database is available online and is expected to foster the use of this promising technique in the diagnosis of pediatric pathologies...

Research Grants26

  1. MR Microimaging of Mouse Brain Development
    Susumu Mori; Fiscal Year: 2007
    ..This project was made possible through collaboration with Drs. Moil (MRI), Sidman (neuroanatomy), and Miller (computational neuroanatomy). ..
  2. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2001
    ....
  3. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2006
    ....
  4. MR-Based Study of Hypomyelination by Lead Poisoning
    Susumu Mori; Fiscal Year: 2007
    ..Using the MRI-based technique and normative database established under Aim 1 and 2, we will perform comprehensive myelination studies to examine the hypothesis [unreadable] [unreadable]..
  5. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2007
    ..Aim 3: Acquisition and analyses of DTI data of normal aging population: In this aim, we will expand our effort to middle age and aging population to study normal aging process of the white matter. ..
  6. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2007
    ..For type specifications, see instructions on page 6.) RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page 1 Description, ..
  7. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2008
    ..Aim 3: Acquisition and analyses of DTI data of normal aging population: In this aim, we will expand our effort to middle age and aging population to study normal aging process of the white matter. ..
  8. DtiStudio: Resource Software for Diffusion Tensor Imaging
    Susumu Mori; Fiscal Year: 2009
    ..This also provides an environment for open source. Aim 4: Upgrade to integrate new technologies. ..
  9. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2009
    ..Aim 3: Acquisition and analyses of DTI data of normal aging population: In this aim, we will expand our effort to middle age and aging population to study normal aging process of the white matter. ..
  10. MR Microimaging of Mouse Brain Development
    Susumu Mori; Fiscal Year: 2009
    ..We believe that these atlases will be important resources for a wide range of neuroscience researches. ..
  11. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2010
    ..Aim 3: Acquisition and analyses of DTI data of normal aging population: In this aim, we will expand our effort to middle age and aging population to study normal aging process of the white matter. ..
  12. DtiStudio: Resource Software for Diffusion Tensor Imaging
    Susumu Mori; Fiscal Year: 2010
    ..This also provides an environment for open source. Aim 4: Upgrade to integrate new technologies. ..
  13. MR-Based Study of Hypomyelination by Lead Poisoning
    Susumu Mori; Fiscal Year: 2006
    ..Using the MRI-based technique and normative database established under Aim 1 and 2, we will perform comprehensive myelination studies to examine the hypothesis [unreadable] [unreadable]..
  14. MR Microimaging of Mouse Brain Development
    Susumu Mori; Fiscal Year: 2006
    ..This project was made possible through collaboration with Drs. Moil (MRI), Sidman (neuroanatomy), and Miller (computational neuroanatomy). ..
  15. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2002
    ....
  16. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2003
    ....
  17. Mouse Brain Development Study by MRI
    Susumu Mori; Fiscal Year: 2003
    ..abstract_text> ..
  18. MR-Based Study of Hypomyelination by Lead Poisoning
    Susumu Mori; Fiscal Year: 2004
    ..Using the MRI-based technique and normative database established under Aim 1 and 2, we will perform comprehensive myelination studies to examine the hypothesis ..
  19. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2003
    ....
  20. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2004
    ....
  21. MR Microimaging of Alzheimer's Mouse Models
    Susumu Mori; Fiscal Year: 2005
    ..Hypothesis: The amyloid plaque detection and volume measurements can be achieved in vivo. To confirm these hypotheses, 2 mouse strains of the AD model will be studied at 4 different ages. ..
  22. MR Microimaging of Mouse Brain Development
    Susumu Mori; Fiscal Year: 2004
    ..This project was made possible through collaboration with Drs. Moil (MRI), Sidman (neuroanatomy), and Miller (computational neuroanatomy). ..
  23. Human White Matter Tract Mapping by Diffusion MRI
    Susumu Mori; Fiscal Year: 2005
    ....
  24. MR Microimaging of Mouse Brain Development
    Susumu Mori; Fiscal Year: 2005
    ..This project was made possible through collaboration with Drs. Moil (MRI), Sidman (neuroanatomy), and Miller (computational neuroanatomy). ..
  25. MR-Based Study of Hypomyelination by Lead Poisoning
    Susumu Mori; Fiscal Year: 2005
    ..Using the MRI-based technique and normative database established under Aim 1 and 2, we will perform comprehensive myelination studies to examine the hypothesis ..
  26. MR Microimaging of Mouse Brain Development
    Susumu Mori; Fiscal Year: 2010
    ..We believe that these atlases will be important resources for a wide range of neuroscience researches. ..