Peter J Mogayzel

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Cystic fibrosis pulmonary guidelines. Chronic medications for maintenance of lung health
    Peter J Mogayzel
    Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Am J Respir Crit Care Med 187:680-9. 2013
  2. pmc Membrane-associated heparan sulfate is not required for rAAV-2 infection of human respiratory epithelia
    Michael P Boyle
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore MD 21205, USA
    Virol J 3:29. 2006
  3. ncbi request reprint Mucus removal is impaired in children with cystic fibrosis who have been infected by Pseudomonas aeruginosa
    Beth L Laube
    The Johns Hopkins Medical Institutions, Baltimore, Md Electronic address
    J Pediatr 164:839-45. 2014
  4. pmc Environmental allergies and respiratory morbidities in cystic fibrosis
    Joseph M Collaco
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Pediatr Pulmonol 48:857-64. 2013
  5. doi request reprint Exercise improves lung function and habitual activity in children with cystic fibrosis
    Shruti M Paranjape
    Eudowood Division of Pediatric Respiratory Sciences, Department of Pediatrics, Johns Hopkins University, Baltimore, MD 21287, USA
    J Cyst Fibros 11:18-23. 2012
  6. pmc Acute inhalation of hypertonic saline does not improve mucociliary clearance in all children with cystic fibrosis
    Beth L Laube
    Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    BMC Pulm Med 11:45. 2011
  7. pmc Nutritional outcomes following gastrostomy in children with cystic fibrosis
    Gia M Bradley
    Division of Pediatric Gastroenterology and Nutrition, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Pediatr Pulmonol 47:743-8. 2012
  8. pmc A pilot study to examine the effect of chronic treatment with immunosuppressive drugs on mucociliary clearance in a vagotomized murine model
    Abhiram R Bhashyam
    Department of Biomedical Engineering, The Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
    PLoS ONE 7:e45312. 2012
  9. pmc Location and duration of treatment of cystic fibrosis respiratory exacerbations do not affect outcomes
    J Michael Collaco
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, 200 N Wolfe Street, David M Rubenstein Building, 3rd Floor, Baltimore, MD 21287, USA
    Am J Respir Crit Care Med 182:1137-43. 2010
  10. doi request reprint Transient effectiveness of vitamin D2 therapy in pediatric cystic fibrosis patients
    Deanna M Green
    Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    J Cyst Fibros 9:143-9. 2010

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Cystic fibrosis pulmonary guidelines. Chronic medications for maintenance of lung health
    Peter J Mogayzel
    Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Am J Respir Crit Care Med 187:680-9. 2013
    ..These guidelines provide up-to-date evidence of safety and efficacy of chronic treatments of CF lung disease, including the use of novel therapies that have not previously been included in CF pulmonary guidelines...
  2. pmc Membrane-associated heparan sulfate is not required for rAAV-2 infection of human respiratory epithelia
    Michael P Boyle
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore MD 21205, USA
    Virol J 3:29. 2006
    ..The aim of this investigation was to determine the necessity of cell membrane HSPG for efficient infection by rAAV-2...
  3. ncbi request reprint Mucus removal is impaired in children with cystic fibrosis who have been infected by Pseudomonas aeruginosa
    Beth L Laube
    The Johns Hopkins Medical Institutions, Baltimore, Md Electronic address
    J Pediatr 164:839-45. 2014
    ..To determine if mucus removal is impaired in children with cystic fibrosis (CF) who have been recently infected with Pseudomonas aeruginosa...
  4. pmc Environmental allergies and respiratory morbidities in cystic fibrosis
    Joseph M Collaco
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Pediatr Pulmonol 48:857-64. 2013
    ..Studies using small study samples focusing on environmental allergies in CF have had inconsistent results. Our objective was to examine the role of environmental allergies in upper and lower respiratory tract morbidities in CF...
  5. doi request reprint Exercise improves lung function and habitual activity in children with cystic fibrosis
    Shruti M Paranjape
    Eudowood Division of Pediatric Respiratory Sciences, Department of Pediatrics, Johns Hopkins University, Baltimore, MD 21287, USA
    J Cyst Fibros 11:18-23. 2012
    ..Because physical activity has been shown to improve lung function and quality of life (QoL), developing routine exercise programs can benefit this patient population...
  6. pmc Acute inhalation of hypertonic saline does not improve mucociliary clearance in all children with cystic fibrosis
    Beth L Laube
    Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    BMC Pulm Med 11:45. 2011
    ....
  7. pmc Nutritional outcomes following gastrostomy in children with cystic fibrosis
    Gia M Bradley
    Division of Pediatric Gastroenterology and Nutrition, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Pediatr Pulmonol 47:743-8. 2012
    ..Our study evaluated if gastrostomy (GT) placement increases the likelihood of reaching that goal compared to a standardized nutrition protocol...
  8. pmc A pilot study to examine the effect of chronic treatment with immunosuppressive drugs on mucociliary clearance in a vagotomized murine model
    Abhiram R Bhashyam
    Department of Biomedical Engineering, The Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
    PLoS ONE 7:e45312. 2012
    ..We hypothesized that chronic treatment with a commonly prescribed regimen of immunosuppressive drugs significantly impairs MCC. We tested this hypothesis in a murine model of lung transplantation...
  9. pmc Location and duration of treatment of cystic fibrosis respiratory exacerbations do not affect outcomes
    J Michael Collaco
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, 200 N Wolfe Street, David M Rubenstein Building, 3rd Floor, Baltimore, MD 21287, USA
    Am J Respir Crit Care Med 182:1137-43. 2010
    ..The optimal means of delivering therapy remains unclear...
  10. doi request reprint Transient effectiveness of vitamin D2 therapy in pediatric cystic fibrosis patients
    Deanna M Green
    Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    J Cyst Fibros 9:143-9. 2010
    ..The effectiveness of current treatment recommendations for vitamin D insufficiency in children with CF is unknown. Therefore, we assessed the effectiveness of vitamin D(2) 50,000 IU once daily for 28 days for vitamin D insufficiency...
  11. ncbi request reprint Bilateral diaphragm paralysis following lung transplantation and cardiac surgery in a 17-year-old
    Peter J Mogayzel
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Heart Lung Transplant 21:710-2. 2002
    ..This patient required prolonged mechanical ventilation post-operatively; however, he eventually had adequate recovery of diaphragm function to wean from mechanical ventilation...
  12. ncbi request reprint cis-Acting elements within CFTR 5'-flanking DNA are not sufficient to decrease gene expression in response to phorbol ester
    Peter J Mogayzel
    Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Park 316, Baltimore, MD 21287 2533, USA
    Biochim Biophys Acta 1576:306-15. 2002
    ....
  13. ncbi request reprint Effect of adeno-associated virus-specific immunoglobulin G in human amniotic fluid on gene transfer
    Michael P Boyle
    Department of Medicine, The Johns Hopkins University School of Medicine, Jefferson B1 170, 600 North Wolfe Street, Baltimore, MD 21287 8922, USA
    Hum Gene Ther 14:365-73. 2003
    ..These studies demonstrate that AF from some individuals contains AAV-specific IgG that can inhibit gene transfer...
  14. ncbi request reprint Cyclosporin and tacrolimus do not potentiate oxidative damage in pulmonary epithelial cells
    Peter J Mogayzel
    Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Hospital, 600 North Wolfe Street, Park 316, Baltimore MD 21287, USA
    Transpl Int 16:709-12. 2003
    ..These studies demonstrated that H(2)O(2), CsA, and tacrolimus treatments decrease survival of pulmonary epithelial cells. However, CsA and tacrolimus do not further potentiate H(2)O(2)-induced toxicity...
  15. pmc Longitudinal association between medication adherence and lung health in people with cystic fibrosis
    Michelle N Eakin
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21224, USA
    J Cyst Fibros 10:258-64. 2011
    ..This study examined the relationship of medication adherence to frequency of pulmonary exacerbation and rate of decline in FEV(1)% predicted (FEV(1))...
  16. pmc CFTR transcription defects in pancreatic sufficient cystic fibrosis patients with only one mutation in the coding region of CFTR
    Molly B Sheridan
    McKusick Nathans Institute of Genetic Medicine, 733 North Broadway, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
    J Med Genet 48:235-41. 2011
    ..However, the role of dysfunctional CFTR is uncertain in individuals with mild forms of CF (ie, pancreatic sufficiency) and mutation in only one CFTR gene...
  17. ncbi request reprint Primary snoring and growth failure in a patient with cystic fibrosis
    Kelvin D MacDonald
    Eudowood Division of Pediatric Respiratory Sciences, 200 N Wolfe Street, Baltimore, MD 21287, USA
    Respir Care 54:1727-31. 2009
    ..This case demonstrates that adenotonsillar hypertrophy associated with recurrent pharyngitis and primary snoring might hinder growth in a patient with cystic fibrosis...
  18. doi request reprint Description of a standardized nutrition classification plan and its relation to nutritional outcomes in children with cystic fibrosis
    Amanda Leonard
    Division of Pediatric Gastroenterology and Nutrition, The Johns Hopkins Medical Institutions, USA
    J Pediatr Psychol 35:6-13. 2010
    ..Therefore, we developed a standardized strategy to evaluate nutritional status and create individualized treatment plans to ensure that all patients received the same high-quality care in a busy CF Center...
  19. doi request reprint Pain is a common problem affecting clinical outcomes in adults with cystic fibrosis
    MARGARET HAYES
    Department of Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Chest 140:1598-603. 2011
    ..We hypothesized that pain is common, is associated with psychologic distress, and adversely affects clinical outcomes...
  20. ncbi request reprint Modulation of Sp1 and Sp3 in lung epithelial cells regulates ClC-2 chloride channel expression
    Kathryn W Holmes
    Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, 600 N Wolfe St Park 316, Baltimore, MD 21287 2533, USA
    Am J Respir Cell Mol Biol 29:499-505. 2003
    ..These experiments suggest that the mechanism for postnatal reduction of ClC-2 expression in lung epithelia is based on decreased interaction of Sp1 and Sp3 with the ClC-2 promoter...
  21. ncbi request reprint Pharmacoproteomics of 4-phenylbutyrate-treated IB3-1 cystic fibrosis bronchial epithelial cells
    Om V Singh
    Department of Pediatrics, The Johns Hopkins School of Medicine, Baltimore, Maryland 21209, USA
    J Proteome Res 5:562-71. 2006
    ..Subsets of these proteins were confirmed by immunoblot analysis. These data represent a first-draft of the pharmacoproteomics map of 4-PBA treated cystic fibrosis bronchial epithelial cells...
  22. pmc Multicenter evaluation of infant lung function tests as cystic fibrosis clinical trial endpoints
    Stephanie D Davis
    Department of Pediatrics, North Carolina Children s Hospital, University of North Carolina at Chapel Hill, USA
    Am J Respir Crit Care Med 182:1387-97. 2010
    ..The conducting of clinical trials in infants with cystic fibrosis (CF) has been hindered by lack of sensitive outcome measures...
  23. pmc Early eradication of Pseudomonas aeruginosa in patients with cystic fibrosis
    Bridget Stuart
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2533, USA
    Paediatr Respir Rev 11:177-84. 2010
    ..This article outlines the pathophysiology and clinical implication of Pa acquisition, and reviews the existing treatment regimens aimed at early eradication of Pa in patients with CF...
  24. pmc Vagal control of mucociliary clearance in murine lungs: a study in a chronic preparation
    Abhiram R Bhashyam
    Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Auton Neurosci 154:74-8. 2010
    ....
  25. ncbi request reprint Accuracy of tobramycin levels obtained from central venous access devices in patients with cystic fibrosis is technique dependent
    Peter J Mogayzel
    Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Pediatr Nurs 34:464-8; quiz 468-9. 2008
    ..Therefore, the effect of the volume of saline flush used prior to drawing blood on tobramycin levels obtained from CVADs was investigated to determine the potential for inappropriate drug dosing decisions...
  26. ncbi request reprint Albuterol improves impaired mucociliary clearance after lung transplantation
    Beth L Laube
    Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2533, USA
    J Heart Lung Transplant 26:138-44. 2007
    ..We hypothesized that impairment of MCC is evident soon after lung transplantation and that the defect in MCC can be improved by inhaled beta(2)-adrenergic receptor agonists...
  27. ncbi request reprint Ciprofloxacin-induced renal insufficiency in cystic fibrosis
    Brady S Moffett
    Department of Pharmacy, The Johns Hopkins Medical Institutions, 600 N Wolfe Street, Park 316, Baltimore, MD 21287, USA
    J Cyst Fibros 2:152-4. 2003
    ..The incidence of this adverse effect in children and young adults who have cystic fibrosis is unknown. Multiple mechanisms for ciprofloxacin-induced nephrotoxicity have been proposed...
  28. ncbi request reprint Pulmonary dysfunction in pediatric hematopoietic stem cell transplant patients: overview, diagnostic considerations, and infectious complications
    J Michael Collaco
    Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, Baltimore, Maryland
    Pediatr Blood Cancer 49:117-26. 2007
    ....