Research Topics
| Americo A MigliaccioSummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
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Detail Information
Publications
Vergence-mediated changes in the axis of eye rotation during the human vestibulo-ocular reflex can occur independent of eye positionAmerico A Migliaccio
Eye and Ear Research Unit, Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Sydney, Australia
Exp Brain Res 151:238-48. 2003..5 g and may have contributed to the increased torsional component observed during near viewing. Our data show that vergence-mediated eye movements obey a VOR/Listing's Law compromise strategy independent of the initial eye position...
Axis of eye rotation changes with head-pitch orientation during head impulses about earth-verticalAmerico A Migliaccio
Laboratory of Vestibular Neurophysiology, Department of Otolaryngology Head and Neck Surgery School of Medicine, Johns Hopkins University, Baltimore, MD, USA
J Assoc Res Otolaryngol 7:140-50. 2006..Thus, even when the orientation of Listing's plane and eye position in the orbit are fixed, the axis of eye rotation during the VOR reflects a compromise between the requirements of Listing's law and a perfectly compensatory VOR...
Vergence-mediated modulation of the human angular vestibulo-ocular reflex is unaffected by canal pluggingAmerico A Migliaccio
Laboratory of Vestibular Neurophysiology, Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins University School of Medicine, Ross Building, Room 710, 720 Rutland Avenue, Baltimore, MD 21205, USA
Exp Brain Res 186:581-7. 2008..We hypothesize that canal plugging, unlike gentamicin or galvanic ablation, has no effect on vergence-mediated modulation of the AVOR because plugging does not preferentially affect irregular afferents...- The vestibulo-ocular reflex response to head impulses rarely decreases after cochlear implantationAmerico A Migliaccio
Laboratory of Vestibular Neurophysiology, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Otol Neurotol 26:655-60. 2005..Measure vestibular function using the head impulse test and assess the change in function due to unilateral cochlear implantation... - The three-dimensional vestibulo-ocular reflex evoked by high-acceleration rotations in the squirrel monkeyAmerico A Migliaccio
Department of Otolaryngology Head and Neck Surgery, Ross Building, Room 710, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
Exp Brain Res 159:433-46. 2004..In addition, we show that the gain, phase and axis of eye rotation during LARP and RALP head rotations can be predicted once the pitch and roll responses are characterized... - Vergence-mediated modulation of the human horizontal vestibulo-ocular reflex is eliminated by a partial peripheral gentamicin lesionAmerico A Migliaccio
Laboratory of Vestibular Neurophysiology, Department of Otolaryngology Head and Neck Surgery, Ross Building, Room 710, Johns Hopkins University School of Medicine, 720 Rutland Ave, Baltimore, MD 21205, USA
Exp Brain Res 159:92-8. 2004..Our findings are consistent with the hypothesis that irregular afferents provide the necessary signal for vergence-mediated modulation of the VOR... - Effect of vestibular rehabilitation on passive dynamic visual acuityMatthew Scherer
Department of Physical Therapy and Rehabilitation Science, University of Maryland, Baltimore, MD, USA
J Vestib Res 18:147-57. 2008..Each subject demonstrated a reduction in the ratio of compensatory saccades to head impulses after VPT. Preliminary data suggest that active gaze stability exercises may contribute to improvements in pDVA in some individuals... - Mechanism of dynamic visual acuity recovery with vestibular rehabilitationMichael C Schubert
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD 21287 0910, USA
Arch Phys Med Rehabil 89:500-7. 2008..To determine why dynamic visual acuity (DVA) improves after vestibular rehabilitation in people with vestibular hypofunction... - Retention of VOR gain following short-term VOR adaptationMichael C Schubert
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, 601 N Caroline St, JHOC Room 6245, Baltimore, MD 21287 0910, USA
Exp Brain Res 187:117-27. 2008..We also show that the adapting head position determines the magnitude of VOR adaptation... - The effect of binocular eye position and head rotation plane on the human torsional vestibuloocular reflexAmerico A Migliaccio
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, MA 21205, USA
Vision Res 46:2475-86. 2006.... - Angular vestibulo-ocular reflex gains correlate with vertigo control after intratympanic gentamicin treatment for Meniere's diseaseFrank R Lin
Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Ann Otol Rhinol Laryngol 114:777-85. 2005..CONCLUSIONS: Our results suggest that successful treatment of Meniere's disease is closely related to attenuation of semicircular canal function as measured by horizontal canal aVOR gains... - The effects of cochlear implantation on vestibular functionThuy Anh N Melvin
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Otol Neurotol 30:87-94. 2009..Determine the risk posed by cochlear implantation (CI) to the labyrinth... - Characterization of the 3D angular vestibulo-ocular reflex in C57BL6 miceAmerico A Migliaccio
Neuroscience Research Australia and the University of New South Wales, Sydney, Australia
Exp Brain Res 210:489-501. 2011..g., squirrel monkeys and humans) suggests that the parallel resting optic axes and/or radially symmetric retinal foveae of primates underlie their characteristically low 3D aVOR gain for roll head rotations... - Adaptation of the vestibulo-ocular reflex for forward-eyed foveate visionAmerico A Migliaccio
Dept of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
J Physiol 588:3855-67. 2010..In contrast, the lateral-eyed chinchilla faces different adaptive demands and thus enlists a different aVOR strategy... - Vestibular hypofunction in the initial postoperative period after surgical treatment of superior semicircular canal dehiscenceYuri Agrawal
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Otol Neurotol 30:502-6. 2009..2) Evaluate whether dehiscence length is associated with risk of postoperative vestibular hypofunction. 3) Compare the prevalences of immediate and late postoperative vestibular hypofunction... - A multichannel semicircular canal neural prosthesis using electrical stimulation to restore 3-d vestibular sensationCharles C Della Santina
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, 601 North Caroline Street, Baltimore, MD 21287, USA
IEEE Trans Biomed Eng 54:1016-30. 2007..Increasing stimulation selectivity via improvements in electrode design, surgical technique and stimulus protocol will likely be required to restore AVOR function over the full range of normal behavior... - Semicircular canal function before and after surgery for superior canal dehiscenceJohn P Carey
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Otol Neurotol 28:356-64. 2007..To characterize semicircular canal function before and after surgery for superior semicircular canal dehiscence (SCD) syndrome... - The under-compensatory roll aVOR does not affect dynamic visual acuityMichael C Schubert
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, 601 N Caroline St, Baltimore, MD, 21287 0910, USA
J Assoc Res Otolaryngol 13:517-25. 2012..For subjects with UVH, the DVA score during passive horizontal impulses is a better indicator of poor gaze stability than during passive roll or pitch... - Dynamic visual acuity during passive head thrusts in canal planesMichael C Schubert
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, 601 N Caroline St, JHOC Rm 6245, Baltimore, MD 21287 0910, USA
J Assoc Res Otolaryngol 7:329-38. 2006..051 LogMAR). These findings suggest that the htDVA test, which does not require scleral coil placement, magnetic field coils, or expensive oculography equipment, can provide a useful quantitative measure of individual SCC function... - The human sound-evoked vestibulo-ocular reflex and its electromyographic correlateMiriam S Welgampola
Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, NSW 2050, Australia
Clin Neurophysiol 120:158-66. 2009..We examined their relationship by measuring the modulation of both responses by gaze and stimulus parameters... - Search-coil head-thrust and caloric tests in Ménière's diseaseHong Ju Park
Department of Otolaryngology--Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland 21287, USA
Acta Otolaryngol 125:852-7. 2005..Two subjects with unilateral MD had 100% UW, but none had >30% asymmetry on HTTs... - The 2D modified head impulse test: a 2D technique for measuring function in all six semi-circular canalsAmerico A Migliaccio
Neuroscience Research Australia and the University of New South Wales, Sydney, Australia
J Vestib Res 21:227-34. 2011..We conclude that 2D eye measurement techniques, such as video pupil-tracking, can be used to test all six canals... - Vestibulo-ocular reflex responses to a multichannel vestibular prosthesis incorporating a 3D coordinate transformation for correction of misalignmentGene Y Fridman
Vestibular NeuroEngineering Laboratory, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, 720 Rutland Ave, Baltimore, MD 21205, USA
J Assoc Res Otolaryngol 11:367-81. 2010.... - Virtual labyrinth model of vestibular afferent excitation via implanted electrodes: validation and application to design of a multichannel vestibular prosthesisRussell Hayden
Johns Hopkins Vestibular NeuroEngineering Laboratory, Baltimore, MD 21287 0910, USA
Exp Brain Res 210:623-40. 2011..The modeling procedure is partially automated and can be readily adapted to other species, including humans... - Modification of compensatory saccades after aVOR gain recoveryMichael C Schubert
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 0910, USA
J Vestib Res 16:285-91. 2006..Our data suggest an inverse, dynamic relationship between the recruitment of CS and the gain of the aVOR... - Orientation of human semicircular canals measured by three-dimensional multiplanar CT reconstructionCharles C Della Santina
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, 601 North Caroline Street, Rm JHOC 6253, Baltimore, MD 21287, USA
J Assoc Res Otolaryngol 6:191-206. 2005..5 +/- 5.1 degrees, and 105.6 +/- 6.6 degrees, respectively. The mean anterior SCC-contralateral posterior SCC angle was 15.3 +/- 7.2 degrees. The absolute orientations of human SCC are more nearly orthogonal than previously reported... - Vergence-mediated changes in Listing's plane do not occur in an eye with superior oblique palsyAmerico A Migliaccio
Neurology Department, Royal Prince Alfred Hospital, Sydney, Australia
Invest Ophthalmol Vis Sci 45:3043-7. 2004..CONCLUSIONS: These results suggest that the superior oblique muscle, at least in part, is responsible for the temporal rotation of Listing's plane that occurs in normal subjects on convergence... - Cerebellar ataxia with bilateral vestibulopathy: description of a syndrome and its characteristic clinical signAmerico A Migliaccio
Neurology Department, Royal Prince Alfred Hospital, Sydney, Australia
Brain 127:280-93. 2004..1 to 1.0 Hz, eye velocity failed to match head velocity, gaze velocity increased, and gaze position errors developed, which were corrected with bursts of saccades, the basis of the clinical sign of an impaired VVOR... - Inexpensive system for real-time 3-dimensional video-oculography using a fluorescent marker arrayAmerico A Migliaccio
Department of Otolaryngology-Head and Neck Surgery, Laboratory of Vestibular Neurophysiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Neurosci Methods 143:141-50. 2005..laniger). The in vivo positional difference between the two methods was <3.1% for each component of 3-D eye position...
Research Grants
- Galvanic Effects on the Human Vestibuloocular ReflexAmerico Migliaccio; Fiscal Year: 2007....