Erin D Michos

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc The JUPITER and AURORA clinical trials for rosuvastatin in special primary prevention populations: perspectives, outcomes, and consequences
    Venkata Narla
    The Ciccarone Preventive Cardiology Center, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Vasc Health Risk Manag 5:1033-42. 2009
  2. pmc Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly
    Sydney B Long
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA
    Clin Interv Aging 6:27-35. 2011
  3. doi request reprint Niacin and statin combination therapy for atherosclerosis regression and prevention of cardiovascular disease events: reconciling the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides: Impact on Global Health Ou
    Erin D Michos
    The Johns Hopkins University School of Medicine, Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland 21287, USA
    J Am Coll Cardiol 59:2058-64. 2012
  4. pmc 25-Hydroxyvitamin D deficiency is associated with fatal stroke among whites but not blacks: The NHANES-III linked mortality files
    Erin D Michos
    Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Nutrition 28:367-71. 2012
  5. pmc Factors associated with low levels of subclinical vascular disease in older adults: multi-ethnic study of atherosclerosis
    Erin D Michos
    Division of Cardiology, Johns Hopkins University, Carnegie 568, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Prev Cardiol 12:72-9. 2009
  6. doi request reprint Favorable cardiovascular risk factor profile is associated with reduced prevalence of coronary artery calcification and inflammation in asymptomatic nondiabetic white men
    Erin D Michos
    Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Prev Cardiol 11:189-94. 2008
  7. doi request reprint Prevalence of low low-density lipoprotein cholesterol with elevated high sensitivity C-reactive protein in the U.S.: implications of the JUPITER (Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin) st
    Erin D Michos
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Division of Cardiology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Am Coll Cardiol 53:931-5. 2009
  8. pmc Serum 25-hydroxyvitamin d levels are not associated with subclinical vascular disease or C-reactive protein in the old order amish
    Erin D Michos
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Calcif Tissue Int 84:195-202. 2009
  9. pmc Sex hormones, sex hormone binding globulin, and abdominal aortic calcification in women and men in the multi-ethnic study of atherosclerosis (MESA)
    Erin D Michos
    Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD 21287, United States
    Atherosclerosis 200:432-8. 2008
  10. ncbi request reprint Vitamin D and cardiovascular disease risk
    Erin D Michos
    Department of Medicine, Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    Curr Opin Clin Nutr Metab Care 11:7-12. 2008

Detail Information

Publications42

  1. pmc The JUPITER and AURORA clinical trials for rosuvastatin in special primary prevention populations: perspectives, outcomes, and consequences
    Venkata Narla
    The Ciccarone Preventive Cardiology Center, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Vasc Health Risk Manag 5:1033-42. 2009
    ..This review outlines the JUPITER and AURORA trials, interprets the data and significance of the results, analyses the drawbacks and impact of both trials and delineates the potential for further clinical trials...
  2. pmc Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly
    Sydney B Long
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA
    Clin Interv Aging 6:27-35. 2011
    ..The implications of this JUPITER subanalysis and the broader role of statins among older adults is the subject of this review...
  3. doi request reprint Niacin and statin combination therapy for atherosclerosis regression and prevention of cardiovascular disease events: reconciling the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides: Impact on Global Health Ou
    Erin D Michos
    The Johns Hopkins University School of Medicine, Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland 21287, USA
    J Am Coll Cardiol 59:2058-64. 2012
    ..This viewpoint summarizes these imaging trials studying niacin and places them in the context of the failure of AIM-HIGH to support the HDL-C-increasing hypothesis...
  4. pmc 25-Hydroxyvitamin D deficiency is associated with fatal stroke among whites but not blacks: The NHANES-III linked mortality files
    Erin D Michos
    Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Nutrition 28:367-71. 2012
    ..25(OH)D deficiency and stroke are more prevalent in blacks. We examined whether low 25(OH)D contributes to the excess risk of fatal stroke in blacks compared with whites...
  5. pmc Factors associated with low levels of subclinical vascular disease in older adults: multi-ethnic study of atherosclerosis
    Erin D Michos
    Division of Cardiology, Johns Hopkins University, Carnegie 568, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Prev Cardiol 12:72-9. 2009
    ..Favorable levels of multiple traditional risk factors, but not several novel risk factors, were associated with subclinical markers of successful cardiovascular aging...
  6. doi request reprint Favorable cardiovascular risk factor profile is associated with reduced prevalence of coronary artery calcification and inflammation in asymptomatic nondiabetic white men
    Erin D Michos
    Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Prev Cardiol 11:189-94. 2008
    ..70; P<.001). Our study supports the notion that a favorable CVD profile is associated with less underlying atherosclerosis and inflammation and further highlights the importance of primary prevention of CVRFs...
  7. doi request reprint Prevalence of low low-density lipoprotein cholesterol with elevated high sensitivity C-reactive protein in the U.S.: implications of the JUPITER (Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin) st
    Erin D Michos
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Division of Cardiology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Am Coll Cardiol 53:931-5. 2009
    ..S. population...
  8. pmc Serum 25-hydroxyvitamin d levels are not associated with subclinical vascular disease or C-reactive protein in the old order amish
    Erin D Michos
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Calcif Tissue Int 84:195-202. 2009
    ..Either there is no causal relationship between 25(OH)D and CVD risk, or if there is, it may be mediated through mechanisms other than subclinical vascular disease severity...
  9. pmc Sex hormones, sex hormone binding globulin, and abdominal aortic calcification in women and men in the multi-ethnic study of atherosclerosis (MESA)
    Erin D Michos
    Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD 21287, United States
    Atherosclerosis 200:432-8. 2008
    ..Conflicting findings exist regarding the associations of sex hormones with subclinical atherosclerosis...
  10. ncbi request reprint Vitamin D and cardiovascular disease risk
    Erin D Michos
    Department of Medicine, Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    Curr Opin Clin Nutr Metab Care 11:7-12. 2008
    ..25-Hydroxyvitamin D deficiency has been identified as a potential novel cardiovascular disease risk factor. This review outlines what is known about the association of 25-hydroxyvitamin D levels and cardiovascular disease risk...
  11. ncbi request reprint Vitamin D deficiency and the risk of incident Type 2 diabetes
    Erin D Michos
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Future Cardiol 5:15-8. 2009
    ....
  12. ncbi request reprint Differences in vitamin D status as a possible contributor to the racial disparity in peripheral arterial disease
    Jared P Reis
    Welch Center for Prevention, Epidemiology, and Clinical Research and the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21287, USA
    Am J Clin Nutr 88:1469-77. 2008
    ..Racial differences in cardiovascular risk factors do not fully explain the higher prevalence of lower-extremity peripheral arterial disease (PAD) in black adults...
  13. ncbi request reprint Framingham risk equation underestimates subclinical atherosclerosis risk in asymptomatic women
    Erin D Michos
    Ciccarone Preventive Cardiology Center, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Atherosclerosis 184:201-6. 2006
    ..However, the adequacy of FRE for identifying asymptomatic women with CAC is unknown...
  14. doi request reprint Relation between self-reported physical activity level, fitness, and cardiometabolic risk
    Camille Michael Minder
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland
    Am J Cardiol 113:637-43. 2014
    ..In conclusion, self-reported physical activity level and directly measured fitness are moderately correlated, and the latter is more strongly associated with a protective cardiovascular risk profile...
  15. pmc C-reactive protein level and the incidence of eligibility for statin therapy: the multi-ethnic study of atherosclerosis
    Devin M Mann
    Department of Medicine, Division of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts 02119, USA
    Clin Cardiol 36:15-20. 2013
    ..This analysis estimates the proportion of people with elevated CRP that become statin eligible over time...
  16. pmc Impact of fitness versus obesity on routinely measured cardiometabolic risk in young, healthy adults
    Michael N Vranian
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA
    Am J Cardiol 111:991-5. 2013
    ..These findings underscore the need for weight loss in obese patients and suggest an unmeasured benefit of fitness...
  17. pmc Prediction of coronary artery calcium progression in individuals with low Framingham Risk Score: the Multi-Ethnic Study of Atherosclerosis
    Tochi M Okwuosa
    Wayne State University School of Medicine, Division of Cardiology, Detroit, Michigan, USA
    JACC Cardiovasc Imaging 5:144-53. 2012
    ..This study sought to determine whether novel markers not involving ionizing radiation could predict coronary artery calcium (CAC) progression in a low-risk population...
  18. ncbi request reprint Coronary artery calcification and inflammation according to various metabolic syndrome definitions
    Venkata Narla
    Johns Hopkins University Ciccarone Preventive Cardiology Center, Baltimore, MD, USA
    J Cardiometab Syndr 4:33-9. 2009
    ..69 (95% CI, 1.04-2.73), 1.84 (95% CI, 1.14-2.95), and 1.66 (95% CI, 1.05-2.62), respectively. MS is associated with increased subclinical atherosclerosis and inflammation irrespective of various definitions...
  19. pmc 25-Hydroxyvitamin D and parathyroid hormone are not associated with carotid intima-media thickness or plaque in the multi-ethnic study of atherosclerosis
    Marc Blondon
    From the Department of Epidemiology M B, D S S, J D K, B K, I H d B, Division of Nephrology and Kidney Research Institute M S, B K, I H d B, Department of Laboratory Medicine A N H, Department of Environmental and Occupational Health Sciences J D K, Department of Medicine D S S, J D K, B K, I H d B, Cardiovascular Health Research Unit M B, D S S, University of Washington, Seattle, WA Department of Medicine, Geneva University Hospitals, Geneva, Switzerland M B Division of Nephrology, University of California, San Diego, CA J H I Department of Medicine, Johns Hopkins University, Baltimore, MD E D M and Divison of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI C K, A D G, J H S
    Arterioscler Thromb Vasc Biol 33:2639-45. 2013
    ..Observational evidence supports independent associations of 25-hydroxyvitamin D (25-OHD) and parathyroid hormone (PTH) with cardiovascular risk. A plausible hypothesis for these associations is accelerated development of atherosclerosis...
  20. pmc 25-hydroxyvitamin D levels and the risk of mortality in the general population
    Michal L Melamed
    Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Ave, Ullmann 615, Bronx, NY 10461, USA
    Arch Intern Med 168:1629-37. 2008
    ..However, whether low serum 25(OH)D levels are associated with mortality in the general population is unknown...
  21. pmc Comparison of the racial/ethnic prevalence of regular aspirin use for the primary prevention of coronary heart disease from the multi-ethnic study of atherosclerosis
    Daniel R Sanchez
    Department of Medicine, University of California, Los Angeles, California, USA
    Am J Cardiol 107:41-6. 2011
    ..In conclusion, regular aspirin use in adults at increased and high risk for coronary heart disease remains suboptimal. Important racial/ethnic disparities exist for unclear reasons...
  22. ncbi request reprint Comparison of coronary calcium and stress myocardial perfusion imaging in apparently healthy siblings of individuals with premature coronary artery disease
    Roger S Blumenthal
    The Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 97:328-33. 2006
    ..These screening tests may reflect different aspects or stages of coronary disease in an asymptomatic middle-age population...
  23. pmc Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004
    Michal L Melamed
    Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
    Arterioscler Thromb Vasc Biol 28:1179-85. 2008
    ..The purpose of this study was to determine the association between 25-hydroxyvitamin D (25(OH)D) levels and the prevalence of peripheral arterial disease (PAD) in the general United States population...
  24. pmc Serum vitamin D, parathyroid hormone levels, and carotid atherosclerosis
    Jared P Reis
    Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Atherosclerosis 207:585-90. 2009
    ..Additional research is needed to determine whether vitamin D may influence the progression of atherosclerosis, including the effects of supplementation on the atherosclerotic process...
  25. doi request reprint Vitamin D status and cardiometabolic risk factors in the United States adolescent population
    Jared P Reis
    Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Pediatrics 124:e371-9. 2009
    ..We examined whether low serum vitamin D levels (25-hydroxyvitamin D [25(OH)D]) are associated with cardiovascular risk factors in US adolescents aged 12 to 19 years...
  26. doi request reprint Association between resting heart rate and inflammatory biomarkers (high-sensitivity C-reactive protein, interleukin-6, and fibrinogen) (from the Multi-Ethnic Study of Atherosclerosis)
    Seamus P Whelton
    Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland Electronic address
    Am J Cardiol 113:644-9. 2014
    ..In conclusion, an increased HR at rest was associated with a higher level of inflammation among an ethnically diverse group of subjects without known cardiovascular disease...
  27. doi request reprint High prevalence of cardiometabolic risk factors in women considered low risk by traditional risk assessment
    Irene S Pollin
    Sister to Sister, Everyone Has a Heart Foundation, Bethesda, Maryland, USA
    J Womens Health (Larchmt) 17:947-53. 2008
    ....
  28. doi request reprint Narrowing Sex Differences in Lipoprotein Cholesterol Subclasses Following Mid-Life: The Very Large Database of Lipids (VLDL-10B)
    Kristopher J Swiger
    The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD
    J Am Heart Assoc 3:e000851. 2014
    ..We hypothesized that the average lipid profile of women undergoes unfavorable changes compared with men after midlife...
  29. ncbi request reprint Detection of high-risk young adults and women by coronary calcium and National Cholesterol Education Program Panel III guidelines
    Khurram Nasir
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Coll Cardiol 46:1931-6. 2005
    ....
  30. ncbi request reprint Relation of family history of premature coronary heart disease and metabolic risk factors to risk of coronary arterial calcium in asymptomatic subjects
    Erin D Michos
    Ciccarone Preventative Cardiology Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 95:655-7. 2005
    ..Our study demonstrated that a familial propensity to subclinical atherosclerosis interacts with the presence of >/=2 metabolic RFs, magnifying the risks for those exposed to both...
  31. ncbi request reprint Vitamin D in atherosclerosis, vascular disease, and endothelial function
    LaPrincess C Brewer
    Department of Medicine, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Curr Drug Targets 12:54-60. 2011
    ..Until the results of these studies are available, we believe it is premature to recommend vitamin D as a therapeutic option in atherosclerosis...
  32. doi request reprint Sex steroid hormone concentrations and risk of death in US men
    Andy Menke
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Epidemiol 171:583-92. 2010
    ..Future studies should be conducted to fully characterize the association of low free and bioavailable testosterone concentrations and mortality in men and to describe the mechanism underlying the association...
  33. ncbi request reprint Women with a low Framingham risk score and a family history of premature coronary heart disease have a high prevalence of subclinical coronary atherosclerosis
    Erin D Michos
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am Heart J 150:1276-81. 2005
    ..We postulated that traditional risk factor assessment might fail to identify a sizeable portion of women with a sibling history for premature CHD as having advanced subclinical atherosclerosis...
  34. pmc Current guidelines for high-density lipoprotein cholesterol in therapy and future directions
    Bishnu H Subedi
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA Greater Baltimore Medical Center, Baltimore, MD, USA
    Vasc Health Risk Manag 10:205-16. 2014
    ..This review will outline current therapies and describe future directions for HDL therapeutics. ..
  35. doi request reprint Evidence-based use of statins for primary prevention of cardiovascular disease
    C Michael Minder
    The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA
    Am J Med 125:440-6. 2012
    ..When appraised together, these data provide compelling evidence to support the use of statins for primary prevention in patients with risk factors for developing coronary heart disease over the next 10 years...
  36. ncbi request reprint Waiting for the National Cholesterol Education Program Adult Treatment Panel IV Guidelines, and in the Meantime, Some Challenges and Recommendations
    Seth S Martin
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland
    Am J Cardiol 110:307-13. 2012
    ....
  37. pmc Association of sex hormones and sex hormone-binding globulin with depressive symptoms in postmenopausal women: the Multiethnic Study of Atherosclerosis
    Laura A Colangelo
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Menopause 19:877-85. 2012
    ....
  38. pmc 25-hydroxyvitamin D levels inversely associate with risk for developing coronary artery calcification
    Ian H De Boer
    Department of Medicine, Division of Nephrology, University of Washington, Seattle, WA 98195, USA
    J Am Soc Nephrol 20:1805-12. 2009
    ..Accelerated development of atherosclerosis may underlie, in part, the increased cardiovascular risk associated with vitamin D deficiency...
  39. doi request reprint Very large database of lipids: rationale and design
    Seth S Martin
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Medicine, Baltimore, Maryland
    Clin Cardiol 36:641-8. 2013
    ..0) is underway. Overall, the Very Large Database of Lipids database provides an opportunity for collaboration and new knowledge generation through careful examination of granular lipid data on a large scale. ..
  40. pmc Pulmonary hyperinflation and left ventricular mass: the Multi-Ethnic Study of Atherosclerosis COPD Study
    Benjamin M Smith
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Circulation 127:1503-11, 1511e1-6. 2013
    ..We therefore hypothesized that residual lung volume in COPD would be associated with greater LV mass...
  41. ncbi request reprint Aspirin and clopidogrel resistance
    Erin D Michos
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Mayo Clin Proc 81:518-26. 2006
    ....
  42. ncbi request reprint Hormone replacement therapy and the cardiovascular system lessons learned and unanswered questions
    Pamela Ouyang
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Coll Cardiol 47:1741-53. 2006
    ..This review outlines the lessons learned from the basic science, animal, observational, and randomized trials, and then summarizes yet-unanswered questions of hormone therapy and cardiovascular risk...