Sharon A McGrath-Morrow

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Transcriptional responses of neonatal mouse lung to hyperoxia by Nrf2 status
    Sharon A McGrath-Morrow
    Department of Pediatrics, Division of Pediatric Pulmonary, Johns Hopkins School of Medicine, Baltimore, MD, United States Electronic address
    Cytokine 65:4-9. 2014
  2. ncbi request reprint The impact of bronchopulmonary dysplasia on caregiver health related quality of life during the first 2 years of life
    Sharon A McGrath-Morrow
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 2533, USA
    Pediatr Pulmonol 48:579-86. 2013
  3. pmc Safety and caregiver satisfaction with gastrostomy in patients with Ataxia Telangiectasia
    Maureen A Lefton-Greif
    The Ataxia Telangiectasia Clinical Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Orphanet J Rare Dis 6:23. 2011
  4. ncbi request reprint Polysomnography in preterm infants and children with chronic lung disease
    Sharon A McGrath-Morrow
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287 2533, USA
    Pediatr Pulmonol 47:172-9. 2012
  5. ncbi request reprint Exposure to neonatal cigarette smoke causes durable lung changes but does not potentiate cigarette smoke-induced chronic obstructive pulmonary disease in adult mice
    Sharon McGrath-Morrow
    Division of Pediatric Pulmonary, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2533, USA
    Exp Lung Res 37:354-63. 2011
  6. doi request reprint Evaluation and management of pulmonary disease in ataxia-telangiectasia
    Sharon A McGrath-Morrow
    Division of Pediatric Pulmonary, Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2533, USA
    Pediatr Pulmonol 45:847-59. 2010
  7. pmc Neonatal hyperoxia contributes additively to cigarette smoke-induced chronic obstructive pulmonary disease changes in adult mice
    Sharon A McGrath-Morrow
    Department of Pediatrics, Division of Pediatric Pulmonary, Suite 3029, 200 N Wolfe St Baltimore, MD 21287 2533, USA
    Am J Respir Cell Mol Biol 45:610-6. 2011
  8. ncbi request reprint The effect of neonatal hyperoxia on the lung of p21Waf1/Cip1/Sdi1-deficient mice
    Sharon A McGrath-Morrow
    Department of Pediatrics, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD 21287 2533, USA
    Am J Respir Cell Mol Biol 30:635-40. 2004
  9. pmc Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging mice
    Min Yee
    Department of Pediatrics, School of Medicine and Dentistry, The University of Rochester, Rochester, New York, USA
    Am J Pathol 178:2601-10. 2011
  10. ncbi request reprint Respiratory medication adherence in chronic lung disease of prematurity
    J Michael Collaco
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Medical Institutions, David M Rubenstein Building, 200 North Wolfe Street, Baltimore, Maryland 21287, USA
    Pediatr Pulmonol 47:283-91. 2012

Detail Information

Publications25

  1. pmc Transcriptional responses of neonatal mouse lung to hyperoxia by Nrf2 status
    Sharon A McGrath-Morrow
    Department of Pediatrics, Division of Pediatric Pulmonary, Johns Hopkins School of Medicine, Baltimore, MD, United States Electronic address
    Cytokine 65:4-9. 2014
    ..To determine if Nrf2 activation modulates cell cycle regulatory pathway genes associated with growth arrest we examined the gene expression in the lungs of Nrf2(-/-) and Nrf2(+/+) neonatal mice at one and 3days of hyperoxia exposure...
  2. ncbi request reprint The impact of bronchopulmonary dysplasia on caregiver health related quality of life during the first 2 years of life
    Sharon A McGrath-Morrow
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 2533, USA
    Pediatr Pulmonol 48:579-86. 2013
    ..The objectives of this study were to measure caregiver HRQoL of children with BPD and to identify factors that impact caregiver HRQoL during the first 2 years of life...
  3. pmc Safety and caregiver satisfaction with gastrostomy in patients with Ataxia Telangiectasia
    Maureen A Lefton-Greif
    The Ataxia Telangiectasia Clinical Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Orphanet J Rare Dis 6:23. 2011
    ..The primary purposes of this study were to determine whether GT placement in patients with A-T would be tolerated and associated with caregiver satisfaction...
  4. ncbi request reprint Polysomnography in preterm infants and children with chronic lung disease
    Sharon A McGrath-Morrow
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287 2533, USA
    Pediatr Pulmonol 47:172-9. 2012
    ..To determine the utility of overnight polysomnography (PSG) in assessing pulmonary reserve in stable preterm children with chronic lung disease (CLD)...
  5. ncbi request reprint Exposure to neonatal cigarette smoke causes durable lung changes but does not potentiate cigarette smoke-induced chronic obstructive pulmonary disease in adult mice
    Sharon McGrath-Morrow
    Division of Pediatric Pulmonary, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2533, USA
    Exp Lung Res 37:354-63. 2011
    ..Additional studies may be warranted to determine the utility of these genes as biomarkers of respiratory outcomes...
  6. doi request reprint Evaluation and management of pulmonary disease in ataxia-telangiectasia
    Sharon A McGrath-Morrow
    Division of Pediatric Pulmonary, Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2533, USA
    Pediatr Pulmonol 45:847-59. 2010
    ..Gaps in current knowledge and areas for future research in the field of pulmonary disease in A-T are also outlined...
  7. pmc Neonatal hyperoxia contributes additively to cigarette smoke-induced chronic obstructive pulmonary disease changes in adult mice
    Sharon A McGrath-Morrow
    Department of Pediatrics, Division of Pediatric Pulmonary, Suite 3029, 200 N Wolfe St Baltimore, MD 21287 2533, USA
    Am J Respir Cell Mol Biol 45:610-6. 2011
    ..These results may be relevant to a growing population of preterm children who sustained lung injury in the newborn period and may be exposed to CS in later life...
  8. ncbi request reprint The effect of neonatal hyperoxia on the lung of p21Waf1/Cip1/Sdi1-deficient mice
    Sharon A McGrath-Morrow
    Department of Pediatrics, Johns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD 21287 2533, USA
    Am J Respir Cell Mol Biol 30:635-40. 2004
    ..Furthermore, p21 may be important during recovery from lung injury because it is associated with lower levels of oxidative stress and increased oxidative stress may contribute to alveolar growth abnormalities in the p21(-/-) O(2) lung...
  9. pmc Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging mice
    Min Yee
    Department of Pediatrics, School of Medicine and Dentistry, The University of Rochester, Rochester, New York, USA
    Am J Pathol 178:2601-10. 2011
    ..People exposed to hyperoxia as neonates may be at increased risk for pulmonary hypertension...
  10. ncbi request reprint Respiratory medication adherence in chronic lung disease of prematurity
    J Michael Collaco
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Medical Institutions, David M Rubenstein Building, 200 North Wolfe Street, Baltimore, Maryland 21287, USA
    Pediatr Pulmonol 47:283-91. 2012
    ..Chronic lung disease of prematurity (CLDP) is a frequent complication of premature birth. Infants and children with CLDP are often prescribed complex medication regimens, which can be difficult for families to manage...
  11. ncbi request reprint Inhibition of glutamine synthetase in a549 cells during hyperoxia
    Sharon A McGrath-Morrow
    Department of Pediatrics, Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Am J Respir Cell Mol Biol 27:99-106. 2002
    ..The higher concentration of Gln, however, did not decrease the percentage of cells undergoing necrosis...
  12. ncbi request reprint Type II epithelial cells are critical target for hyperoxia-mediated impairment of postnatal lung development
    Min Yee
    Department of Pediatrics, Box 850, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Ave, NY 14642, USA
    Am J Physiol Lung Cell Mol Physiol 291:L1101-11. 2006
    ..These data suggest that perinatal hyperoxia adversely affects alveolar development by disrupting the proper timing of type II cell proliferation and differentiation into type I cells...
  13. doi request reprint Day care increases the risk of respiratory morbidity in chronic lung disease of prematurity
    Sharon A McGrath-Morrow
    Department of Pediatrics, Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Suite 3029, 200 N Wolfe St, Baltimore, MD 21287 2533, USA
    Pediatrics 126:632-7. 2010
    ..We therefore sought to determine if day care attendance is a significant risk factor for increased respiratory morbidity and symptoms in infants and children with CLDP...
  14. ncbi request reprint Pulmonary function in children and young adults with ataxia telangiectasia
    Sharon A McGrath-Morrow
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland
    Pediatr Pulmonol 49:84-90. 2014
    ..To determine the association between age and lung function in children and young adults with A-T and to identify factors associated with decreased lung function, pulmonary function tests were performed in 100 consecutive people with A-T...
  15. ncbi request reprint Vascular endothelial growth factor receptor 2 blockade disrupts postnatal lung development
    Sharon A McGrath-Morrow
    Department of Pediatric Pulmonary, Johns Hopkins Hospital, Park 316 N Wolfe Street, Baltimore, MD 21287 2533, USA
    Am J Respir Cell Mol Biol 32:420-7. 2005
    ..Therefore, VEGFR-2 blockade in the perinatal period disrupts early alveolar development, but the effect is reversible with time, whereas hyperoxic lung injury is associated with ongoing lung structural impairment...
  16. ncbi request reprint Deglutition and respiration: development, coordination, and practical implications
    Maureen A Lefton-Greif
    Department of Pediatrics, Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Semin Speech Lang 28:166-79. 2007
    ..Identification of infants and children at increased risk for oropharyngeal dysphagia and respiratory disease is critical for optimal intervention. Assessment and management considerations are described...
  17. doi request reprint Elevated serum IL-8 levels in ataxia telangiectasia
    Sharon A McGrath-Morrow
    Division of Pediatric Pulmonology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    J Pediatr 156:682-4.e1. 2010
    ..0001). Elevated serum IL-8 levels in patients with A-T suggest that systemic inflammation may contribute to the disease phenotype...
  18. doi request reprint Frontiers in pulmonary hypertension in infants and children with bronchopulmonary dysplasia
    Joseph M Collaco
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 2533, USA
    Pediatr Pulmonol 47:1042-53. 2012
    ..Finally, the recognition of conditions and exposures that may exacerbate or lead to recurrent PH is needed to help with developing treatment guidelines and preventative strategies that can be used to reduce the burden of disease...
  19. ncbi request reprint Secondhand smoke exposure in preterm infants with bronchopulmonary dysplasia
    Joseph M Collaco
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland
    Pediatr Pulmonol 49:173-8. 2014
    ..Second hand smoke (SHS) has been demonstrated to lead to respiratory morbidities in the general population. The objectives of this study were to assess the prevalence/impact of SHS on preterm infants and children with BPD...
  20. doi request reprint Polysomnographic values in adolescents with ataxia telangiectasia
    Sharon A McGrath-Morrow
    Division of Pediatric Pulmonary, The Johns Hopkins Medical Institution, Baltimore, Maryland, USA
    Pediatr Pulmonol 43:674-9. 2008
    ..Based on these findings, overnight polysomnography should be considered in adolescents with A-T, particularly in those in which there is a clinical suspicion of sleep related breathing abnormalities...
  21. pmc Socio-economic factors and outcomes in chronic lung disease of prematurity
    J Michael Collaco
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Medical Institutions, 200 North Wolfe Street, Baltimore, MD 21287, USA
    Pediatr Pulmonol 46:709-16. 2011
    ....
  22. ncbi request reprint Respiratory outcomes of children with BPD and gastrostomy tubes during the first 2 years of life
    Sharon A McGrath-Morrow
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland
    Pediatr Pulmonol 49:537-43. 2014
    ..This study was done to determine if differences in respiratory outcomes were associated with the presence of a GT or Nissen/GT in children with BPD during the first 2 years of life...
  23. ncbi request reprint Recurrent pneumothoraces associated with nocturnal noninvasive ventilation in a patient with muscular dystrophy
    Lee R Choo-Kang
    Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Pediatr Pulmonol 34:73-8. 2002
    ..Given the increasing utilization of chronic nocturnal bilevel positive airway pressure ventilation, we suggest that healthcare providers and patients be made aware of this potentially life-threatening complication...
  24. ncbi request reprint The effect of glutamine on A549 cells exposed to moderate hyperoxia
    Folasade Ogunlesi
    Department of Pediatrics, Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins Medical Institutions, Park 316 N Wolfe St, Baltimore, MD 21287 2533, USA
    Biochim Biophys Acta 1688:112-20. 2004
    ..These studies suggest that supplemental glutamine may improve cell growth and cell viability and therefore may be beneficial to the lung during exposure to moderate concentrations of supplemental oxygen...
  25. pmc Neonatal hyperoxia enhances the inflammatory response in adult mice infected with influenza A virus
    MICHAEL A O'REILLY
    Department of Pediatrics, Box 850, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Am J Respir Crit Care Med 177:1103-10. 2008
    ..Because survivors of BPD also show increased risk for symptomatic respiratory infections, we investigated how neonatal hyperoxia affected the response of adult mice infected with influenza A virus infection...