Research Topics
| Matthew J McGirtSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Preoperative grading scale to predict survival in patients undergoing resection of malignant primary osseous spinal neoplasmsMatthew J McGirt
Department of Neurological Surgery, Vanderbilt University Medical Center, 4340 The Village at Vanderbilt, Nashville, TN 37232 8618, USA
Spine J 11:190-6. 2011..Large population-based studies of malignant primary osseous spinal neoplasms are lacking and are necessary to have sufficient statistical power to determine if various patient-related factors are in fact significant indicators of prognosis...
Neurological outcome after resection of intramedullary spinal cord tumors in childrenMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
Childs Nerv Syst 24:93-7. 2008..Clinical and radiographic risk factors predictive of postoperative neurological outcome may serve as a guide for surgical risk stratification...
Vertebroplasty and kyphoplasty for the treatment of vertebral compression fractures: an evidenced-based review of the literatureMatthew J McGirt
Spinal Column Biomechanics and Surgical Outcomes Laboratory, The Johns Hopkins Department of Neurosurgery, 600 N Wolfe Street, Meyer 8 161, Baltimore, MD 21218, USA
Spine J 9:501-8. 2009..However, it remains debated whether VP or KP results in superior outcomes versus medical management alone in patients experiencing VCFs...
Symptom recurrence after suboccipital decompression for pediatric Chiari I malformation: analysis of 256 consecutive casesMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, 3553 Newland Rd, Baltimore, MD 21218, USA
Childs Nerv Syst 24:1333-9. 2008..We set out to identify variables at presentation that could identify subgroups most likely to experience incomplete symptom relief after hindbrain decompression for Chiari I malformation...
Risk of cerebral vasopasm after subarachnoid hemorrhage reduced by statin therapy: A multivariate analysis of an institutional experienceMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Neurosurg 105:671-4. 2006..The authors hypothesized that patients chronically treated with statins would have a decreased risk of symptomatic vasospasm after SAH...
Adjustable vs set-pressure valves decrease the risk of proximal shunt obstruction in the treatment of pediatric hydrocephalusMatthew J McGirt
Division of Pediatric Neurosurgery, Department of Neurosurgery, Johns Hopkins School of Medicine, 600 North Wolfe Street, Meyer 8 161, Baltimore, MD 21287, USA
Childs Nerv Syst 23:289-95. 2007..The use of programmable shunt valves has increased dramatically in the practice of pediatric hydrocephalus. Despite theoretical advantages, it remains unclear if the use of programmable vs set-pressure valves affects shunt outcome...
A prospective cohort study of close interval computed tomography and magnetic resonance imaging after primary lumbar discectomy: factors associated with recurrent disc herniation and disc height lossMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
Spine (Phila Pa 1976) 34:2044-51. 2009..Prospective cohort study...
Short-term progressive spinal deformity following laminoplasty versus laminectomy for resection of intradural spinal tumors: analysis of 238 patientsMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Neurosurgery 66:1005-12. 2010..We set out to determine whether the use of laminoplasty (LP) vs laminectomy (LM) has reduced the incidence of subsequent spinal deformity following intradural tumor resection at our institution...
Independent predictors of morbidity after image-guided stereotactic brain biopsy: a risk assessment of 270 casesMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Neurosurg 102:897-901. 2005..5% of patients, respectively. The goal of this study was to perform a critical analysis of risk factors predictive of an enhanced operative risk in frame-based and frameless stereotactic brain biopsy...
Pediatric tethered cord syndrome: response of scoliosis to untethering procedures. Clinical articleMatthew J McGirt
Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Neurosurg Pediatr 4:270-4. 2009..The aim of this study was to determine factors associated with scoliosis progression and whether tethered cord release alone would halt curve progression in pediatric TCS...
Biomechanical comparison of translaminar versus pedicle screws at T1 and T2 in long subaxial cervical constructsMatthew J McGirt
Department of Neurosurgery, Spinal Column Biomechanics and Surgical Outcomes Laboratory, The Johns Hopkins Hospital, Baltimore, Maryland 21218, USA
Neurosurgery 65:167-72; discussion 172. 2009..The first in vitro biomechanical investigation comparing the immediate and postcyclical rigidities of thoracic translaminar versus pedicle screws in posterior constructs crossing the cervicothoracic junction (CTJ)...
Spinal deformity after resection of cervical intramedullary spinal cord tumors in childrenMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, 3553 Newland Rd, Baltimore, MD 21218, USA
Childs Nerv Syst 24:735-9. 2008..It remains unknown which subgroups of patients represent the greatest risk for progressive spinal deformity...
Correlation of a preoperative grading scale with progressive spinal deformity following surgery for intramedullary spinal cord tumors in childrenMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21218, USA
J Neurosurg Pediatr 2:277-81. 2008..The authors propose a preoperative grading scale that correlates with the postoperative development of progressive spinal deformity requiring subsequent fusion...
Correlation of hindbrain CSF flow and outcome after surgical decompression for Chiari I malformationMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, 3553 Newland Rd, Baltimore, MD, 21218, USA
Childs Nerv Syst 24:833-40. 2008..We examined whether ventral or dorsal cerebrospinal fluid (CSF) flow dynamics assessed by cine phase-contrast MRI scans could predict response to posterior fossa decompression for Chiari I malformation...
Effect of hyperglycemia on progressive paraparesis in a rat etastatic spinal tumor modelMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, USA
J Neurosurg Spine 10:9-15. 2009..The goal in this study was to determine whether experimentally induced hyperglycemia accelerates neurological decline in an established animal model of MESCC...
Incidence of spinal deformity after resection of intramedullary spinal cord tumors in children who underwent laminectomy compared with laminoplastyMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21218, USA
J Neurosurg Pediatr 1:57-62. 2008..The authors set out to determine whether laminoplasty in comparison with laminectomy has reduced the incidence of subsequent spinal deformity requiring fusion after IMSCT resection at their institution...
Extent of surgical resection of malignant astrocytomas of the spinal cord: outcome analysis of 35 patientsMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21218, USA
Neurosurgery 63:55-60; discussion 60-1. 2008..We report the outcomes of the surgical management of 35 malignant spinal cord astrocytomas and assess the association of extent of resection with survival after aggressive resection of these tumors...
Resection of intramedullary spinal cord tumors in children: assessment of long-term motor and sensory deficitsMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21218, USA
J Neurosurg Pediatr 1:63-7. 2008..Preoperative predictors of postoperative neurological decline and sensory syndromes have not been investigated and may serve as a guide for surgical risk stratification...
Intraoperative ultrasonography as a guide to patient selection for duraplasty after suboccipital decompression in children with Chiari malformation Type IMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
J Neurosurg Pediatr 2:52-7. 2008....
Independent association of extent of resection with survival in patients with malignant brain astrocytomaMatthew J McGirt
Department of Neurosurgery and Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Neurosurg 110:156-62. 2009..In this study, the authors investigate this issue after primary and revision resection of these lesions...
Preoperative radiographic factors and surgeon experience are associated with cortical breach of C2 pedicle screwsHassan Alosh
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
J Spinal Disord Tech 23:9-14. 2010..A retrospective review study...
Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: a 10-year institutional experienceFrank J Attenello
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA
Ann Surg Oncol 15:2887-93. 2008..Various complications of Gliadel wafers have been reported but not consistently reproduced. We set out to characterize Gliadel-associated morbidity in our 10-year experience with Gliadel wafers for treatment of malignant glioma...
Factors associated with recurrent back pain and cyst recurrence after surgical resection of one hundred ninety-five spinal synovial cysts: analysis of one hundred sixty-seven consecutive casesRisheng Xu
Department of Neurosurgery, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA
Spine (Phila Pa 1976) 35:1044-53. 2010..Retrospective study...
Factors associated with progression-free survival and long-term neurological outcome after resection of intramedullary spinal cord tumors: analysis of 101 consecutive casesGiannina L Garcés-Ambrossi
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
J Neurosurg Spine 11:591-9. 2009..However, factors associated with tumor resectability, tumor recurrence, and long-term neurological outcome are poorly understood...
Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomasMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins School of Medicine, and Neuro Oncology Surgical Outcomes Research Laboratory, Baltimore, Maryland 21231, USA
Neurosurgery 63:700-7; author reply 707-8. 2008..It remains unknown whether the extent of surgical resection affects survival or disease progression in patients with supratentorial low-grade gliomas...
Preoperative Zung Depression Scale predicts outcome after revision lumbar surgery for adjacent segment disease, recurrent stenosis, and pseudarthrosisOwoicho Adogwa
Department of Neurosurgery, The Spinal Column Surgical Quality and Outcomes Research Laboratory, Vanderbilt University Medical Center, 4347 Village at Vanderbilt, Nashville, TN 37232 8618, USA
Spine J 12:179-85. 2012..There remains a paucity of studies assessing the predictive value of baseline depression on outcomes in the setting of revision spine surgery...
Minimum clinically important difference in pain, disability, and quality of life after neural decompression and fusion for same-level recurrent lumbar stenosis: understanding clinical versus statistical significanceScott L Parker
Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN 37232 8618, USA
J Neurosurg Spine 16:471-8. 2012..The MCID remains uninvestigated for any PROs in the setting of revision lumbar surgery for this pathology...
Persistent outpatient hyperglycemia is independently associated with survival, recurrence and malignant degeneration following surgery for hemispheric low grade gliomasKaisorn L Chaichana
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD 21231, USA
Neurol Res 32:442-8. 2010..Hyperglycemia has been shown to augment tumor growth in vitro. However, the effects of persistent hyperglycemia on survival, recurrence and malignant degeneration in patients undergoing surgery for low grade gliomas remain unknown...
Adjuvant treatment with locally delivered OncoGel delays the onset of paresis after surgical resection of experimental spinal column metastasisBeril Gok
Department of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland, USA
Neurosurgery 65:193-9; discussion 199-200. 2009..West Valley City, UT) into the tumor resection cavity at the time of surgery would improve the efficacy of surgical resection with or without external beam radiotherapy (XRT) in a rat model of spinal column metastases...
Posterior-only approach for en bloc sacrectomy: clinical outcomes in 36 consecutive patientsMichelle J Clarke
Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA
Neurosurgery 71:357-64; discussion 364. 2012..However, we have found that en bloc resection and biomechanical reconstruction of the spinal column is possible from a posterior-only approach in many cases...
Association of extent of local tumor invasion and survival in patients with malignant primary osseous spinal neoplasms from the surveillance, epidemiology, and end results (SEER) databaseDebraj Mukherjee
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
World Neurosurg 76:580-5. 2011..The surveillance, epidemiology, and end results (SEER) registry was reviewed to determine whether extent of local tumor invasion at presentation was independently associated with overall survival...
Prognostic significance of contrast-enhancing low-grade gliomas in adults and a review of the literatureKaisorn L Chaichana
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD 21231, USA
Neurol Res 31:931-9. 2009..The prognostic implications of a contrast-enhancing low-grade glioma remain less well understood...
Long-term back pain after a single-level discectomy for radiculopathy: incidence and health care cost analysisScott L Parker
The Johns Hopkins Spinal Column Biomechanics and Surgical Outcomes Laboratory, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Neurosurg Spine 12:178-82. 2010..The authors set out to determine the incidence of and the health care costs associated with mechanical back pain attributed to segmental degeneration or instability at the level of a prior discectomy performed at their institution...
Factors associated with cervical instability requiring fusion after cervical laminectomy for intradural tumor resectionDaniel M Sciubba
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Neurosurg Spine 8:413-9. 2008....
En bloc resection of sacral chordomas aided by frameless stereotactic image guidance: a technical noteHormuzdiyar H Dasenbrock
Department of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland 21287, USA
Neurosurgery 70:82-7; discussion 87-8. 2012..However, obtaining negative margins can be technically challenging. Intraoperative navigation may be helpful in attempting an excision with negative margins...
Cost per quality-adjusted life year gained of revision neural decompression and instrumented fusion for same-level recurrent lumbar stenosis: defining the value of surgical interventionOwoicho Adogwa
Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
J Neurosurg Spine 16:135-40. 2012..The authors set out to assess the 2-year comprehensive cost of revision surgery and determine its value in the treatment of same-level recurrent stenosis...
Determination of minimum clinically important difference in pain, disability, and quality of life after extension of fusion for adjacent-segment diseaseScott L Parker
Departments of Neurosurgery and Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
J Neurosurg Spine 16:61-7. 2012..The MCID remains uninvestigated for any PROs in the setting of revision lumbar surgery for adjacent-segment disease (ASD)...
Hyperglycemia independently increases the risk of perioperative stroke, myocardial infarction, and death after carotid endarterectomyMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Neurosurgery 58:1066-73; discussion 1066-73. 2006..Strict glucose control should be attempted before surgery to minimize the risk of morbidity and mortality after CEA...
Ability of electromyographic monitoring to determine the presence of malpositioned pedicle screws in the lumbosacral spine: analysis of 2450 consecutively placed screwsScott L Parker
The Johns Hopkins Spinal Column Biomechanics and Surgical Outcomes Laboratory, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Neurosurg Spine 15:130-5. 2011....
Risk factors for progressive spinal deformity following resection of intramedullary spinal cord tumors in children: an analysis of 161 consecutive casesKevin C Yao
Department of Neurosurgery, Tufts New England Medical Center, Boston, Massachusetts, USA
J Neurosurg 107:463-8. 2007..However, progressive spinal deformity requiring subsequent fusion occurs in many cases. It remains unknown which subgroups of patients have the greatest risk for progressive spinal deformity...
Surgical management of long intramedullary spinal cord tumorsMichael E Tobias
Department of Neurosurgery, Albert Einstein College of Medicine, Bronx, NY, USA
Childs Nerv Syst 24:219-23. 2008..The incidence of longitudinally extensive tumors involving the cervical, thoracic, and lumbar spine is very low (<1% of intramedullary lesions); hence, little literature exists on the management of this entity...
Neurological outcome after surgical management of adult tethered cord syndromeGiannina L Garcés-Ambrossi
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Neurosurg Spine 11:304-9. 2009....
Suboccipital decompression for Chiari I malformation: outcome comparison of duraplasty with expanded polytetrafluoroethylene dural substitute versus pericranial autograftFrank J Attenello
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
Childs Nerv Syst 25:183-90. 2009....
Prior CSF shunting increases the risk of endoscopic third ventriculostomy failure in the treatment of obstructive hydrocephalus in adultsGraeme Woodworth
The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Neurol Res 29:27-31. 2007..The value of concurrent ETV and ventriculoperitoneal (VP) shunting in patients with frequent shunt failure remains unstudied...
Thoracic kyphotic deformity reduction with a distractible titanium cage via an entirely posterior approachDaniel M Sciubba
Department of Neurological Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Neurosurgery 60:223-30; discussion 230-1. 2007..We describe a technique in which kyphotic deformity of the thoracic and thoracolumbar spine is corrected, decompressed, and stabilized with a circumferential fixation construct from a lone posterior approach...
Recurrence and malignant degeneration after resection of adult hemispheric low-grade gliomasKaisorn L Chaichana
Department of Neurosurgery, Johns Hopkins Neuro Oncology Surgical Outcomes Research Laboratory, Johns Hopkins School of Medicine, Kennedy Krieger Institute, Baltimore, Maryland, USA
J Neurosurg 112:10-7. 2010..The authors set out to determine factors that were independently associated with recurrence and malignant degeneration in patients who underwent resection of a hemispheric low-grade glioma...
Thoracic vertebrectomy and spinal reconstruction via anterior, posterior, or combined approaches: clinical outcomes in 91 consecutive patients with metastatic spinal tumorsRisheng Xu
Department of Neurosurgery, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
J Neurosurg Spine 11:272-84. 2009....
Correlation of preoperative depression and somatic perception scales with postoperative disability and quality of life after lumbar discectomyKaisorn L Chaichana
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Neurosurg Spine 14:261-7. 2011....
Suboccipital decompression for Chiari malformation-associated scoliosis: risk factors and time course of deformity progressionFrank J Attenello
Department of Neurosurgery, The Johns Hopkins School of Medicine, Baltimore, Maryland 21218, USA
J Neurosurg Pediatr 1:456-60. 2008..The authors' goal was to determine the time frame of curvature progression and assess which patient subgroups are at greatest risk for progression of spinal deformity after surgery...
Recurrent disc herniation and long-term back pain after primary lumbar discectomy: review of outcomes reported for limited versus aggressive disc removalMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins Spinal Column Biomechanics and Surgical Outcomes Laboratory, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurosurgery 64:338-44; discussion 344-5. 2009..We reviewed the literature to determine whether outcomes reported after limited discectomy (LD) differed from those reported after aggressive discectomy (AD) with regard to long-term back pain or recurrent disc herniation...
Outcome of Chiari-associated syringomyelia after hindbrain decompression in children: analysis of 49 consecutive casesFrank J Attenello
Department of Neurosurgery, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Neurosurgery 62:1307-13; discussion 1313. 2008..We set out to determine predictors of syrinx improvement after hindbrain decompression for Chiari I- associated syringomyelia...
Recurrent back and leg pain and cyst reformation after surgical resection of spinal synovial cysts: systematic review of reported postoperative outcomesAli Bydon
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Spine J 10:820-6. 2010..However, the role for concomitant fusion and the incidence of recurrent back pain and recurrent cyst formation after surgery remain unclear...
Cost-effectiveness of minimally invasive versus open transforaminal lumbar interbody fusion for degenerative spondylolisthesis associated low-back and leg pain over two yearsScott L Parker
Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
World Neurosurg 78:178-84. 2012..As such, we set out to assess previously unstudied end points of health care cost and cost-utility associated with MIS- versus open-TLIF...
Microdiscectomy improves pain-associated depression, somatic anxiety, and mental well-being in patients with herniated lumbar discRichard Lebow
Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Neurosurgery 70:306-11; discussion 311. 2012..The effects of lumbar discectomy on pain, disability, and physical quality of life are well described. The effects of discectomy on emotional distress and mental well-being are less well understood...
Cost per quality-adjusted life year gained of laminectomy and extension of instrumented fusion for adjacent-segment disease: defining the value of surgical interventionOwoicho Adogwa
Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
J Neurosurg Spine 16:141-6. 2012..It has been shown to have favorable long-term outcomes, but the cost-effectiveness remains unclear. In this study, the authors set out to assess the cost-effectiveness of revision surgery in the treatment of ASD over a 2-year period...
Biomechanical comparison between C-7 lateral mass and pedicle screws in subaxial cervical constructs. Presented at the 2009 Joint Spine Meeting. Laboratory investigationRisheng Xu
Medical Scientist Training Program, Johns Hopkins School of Medicine, Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Neurosurg Spine 13:688-94. 2010..The aim of this study was to conduct the first in vitro biomechanical comparison of immediate and postcyclical rigidities of C-7 lateral mass versus C-7 pedicle screws in posterior C4-7 constructs...
Persistent outpatient hyperglycemia is independently associated with decreased survival after primary resection of malignant brain astrocytomasMatthew J McGirt
Department of Neurosurgery, Johns Hopkins School of Medicine, and The Johns Hopkins Neuro oncology Surgical Outcomes Research Laboratory, Baltimore, Maryland, USA
Neurosurgery 63:286-91; discussion 291. 2008..We hypothesized that persistent hyperglycemic states in the outpatient setting may serve as a prognostic marker of decreased survival in patients with malignant brain astrocytomas...
Long-term clinical outcomes following en bloc resections for sacral chordomas and chondrosarcomas: a series of twenty consecutive patientsPatrick C Hsieh
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Spine (Phila Pa 1976) 34:2233-9. 2009..Retrospective study of 20 consecutive patients who underwent en bloc tumor excision of sacral chordomas and chondrosarcomas...
Survival of patients with malignant primary osseous spinal neoplasms: results from the Surveillance, Epidemiology, and End Results (SEER) database from 1973 to 2003Debraj Mukherjee
Department of Neurosurgery, Cedars Sinai Medical Center, Los Angeles, California, USA
J Neurosurg Spine 14:143-50. 2011....
Preoperative statin and diuretic use influence the presentation of patients undergoing carotid endarterectomy: results of a large single-institution case-control studyBenjamin S Brooke
Department of Surgery, Division of Vascular Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA
J Vasc Surg 45:298-303. 2007..We undertook this study to see whether preoperative medication use or patient characteristics were associated with the presence of symptomatic cerebrovascular disease at the time of operation...
The efficacy of carmustine wafers for older patients with glioblastoma multiforme: prolonging survivalKaisorn L Chaichana
Department of Neurosurgery, The Johns Hopkins Neuro Oncology Surgical Outcomes Research Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Neurol Res 33:759-64. 2011..Peak incidence of glioblastoma multiforme (GBM) occurs in individuals aged 65 years and older. The goal was to evaluate the efficacy of carmustine wafers in prolonging survival for older GBM patients...
Trans-foraminal versus posterior lumbar interbody fusion: comparison of surgical morbidityVivek A Mehta
Johns Hopkins School of Medicine, and Johns Hopkins Spinal Column Biomechanics and Surgical Outcomes Laboratory, Baltimore, MD, USA
Neurol Res 33:38-42. 2011..We review our experience with TLIF versus PLIF to compare operative complications...
Asymptomatic same-site recurrent disc herniation after lumbar discectomy: results of a prospective longitudinal study with 2-year serial imagingRichard L Lebow
Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Spine (Phila Pa 1976) 36:2147-51. 2011..This is a prospective cohort study with serial imaging...
Association of preoperative depression and survival after resection of malignant brain astrocytomaMuraya Gathinji
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD 21231, USA
Surg Neurol 71:299-303, discussion 303. 2009..We set out to determine whether patients with a diagnosis of clinical depression before surgery experienced decreased survival independent of treatment modality or degree of disability...
En bloc spondylectomy for treatment of tumor-induced osteomalaciaDaniel M Sciubba
Department of Neurosurgery, National Institutes of Health, Bethesda, MD, USA
J Neurosurg Spine 11:600-4. 2009..This case suggests that radical spondylectomy may be beneficial in the management of metabolically or endocrinologically active tumors of the spine...
Bilateral traumatic dislocation without fracture of the lumbosacral junction: case report and review of the literatureRisheng Xu
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Spine (Phila Pa 1976) 36:E662-8. 2011..Case report...
Translaminar versus pedicle screw fixation of C2: comparison of surgical morbidity and accuracy of 313 consecutive screwsScott L Parker
Department of Neurosurgery, The Johns Hopkins University School of Medicine, Johns Hopkins Spinal Column Biomechanics and Surgical Outcomes Laboratory, Baltimore, Maryland, USA
Neurosurgery 64:343-8; discussion 348-9. 2009..It is unclear if TL versus PD screw fixation of C2 is truly associated with less operative morbidity, greater accuracy of screw placement, or equivalent durability...
Incidence of symptomatic retethering after surgical management of pediatric tethered cord syndrome with or without duraplastyRoger Samuels
Department of Neurosurgery, Johns Hopkins School of Medicine, 600 N Wolfe Street, Meyer 8 161, Baltimore, MD 21287, USA
Childs Nerv Syst 25:1085-9. 2009..primary closure...
Long-term outcomes of revision fusion for lumbar pseudarthrosis: clinical articleOwoicho Adogwa
Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
J Neurosurg Spine 15:393-8. 2011..The aim of this study was to assess, using validated patient-reported outcomes measures, the long-term effectiveness of revision arthrodesis in the treatment of symptomatic pseudarthrosis...
Cost-effectiveness of multilevel hemilaminectomy for lumbar stenosis-associated radiculopathyScott L Parker
Department of Neurosurgery, Vanderbilt University Medical Center, 4347 Village at Vanderbilt, Nashville, TN 37232 8618, USA
Spine J 11:705-11. 2011..However, given rising health-care costs, attention has been turned to question the cost-effectiveness of lumbar decompressive procedures. The cost-effectiveness of multilevel hemilaminectomy for radiculopathy remains unclear...
Simvastatin for the prevention of symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage: a single-institution prospective cohort studyMatthew J McGirt
Department of Neurosurgery, Johns Hopkins University Hospital, Baltimore, Maryland, USA
J Neurosurg 110:968-74. 2009..The authors conducted a prospective observational study to determine whether a standardized regimen of simvastatin would reduce the incidence of cerebral vasospasm and improve neurological outcomes in patients with aSAH...
Frameless image-guided stereotactic brain biopsy procedure: diagnostic yield, surgical morbidity, and comparison with the frame-based techniqueGraeme F Woodworth
Department of Neurosurgery, The Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Neurosurg 104:233-7. 2006..Few authors have evaluated this procedure, analyzed preoperative predictors of diagnostic yield, or explored the differences in diagnostic yield and morbidity rate between the frameless and frame-based techniques...
Accuracy of frameless and frame-based image-guided stereotactic brain biopsy in the diagnosis of glioma: comparison of biopsy and open resection specimenGraeme Woodworth
Departments of Neurosurgery and Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Neurol Res 27:358-62. 2005..Large tumor volume had a higher incidence of non-concordance. Increasing the number of specimens taken through the long dimension of large tumors may improve diagnostic accuracy...
Persistent perioperative hyperglycemia as an independent predictor of poor outcome after aneurysmal subarachnoid hemorrhageMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Neurosurg 107:1080-5. 2007..It remains to be clarified whether a single hyperglycemic event or persistent hyperglycemia is predictive of poor outcome after aneurysmal SAH...
Relationship of cine phase-contrast magnetic resonance imaging with outcome after decompression for Chiari I malformationsMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland, USA
Neurosurgery 59:140-6; discussion 140-6. 2006..Cine phase-contrast magnetic resonance imaging may be a valuable tool in identifying patients who are less likely to respond to surgical decompression for Chiari I malformation...
The syndrome of hydrocephalus in young and middle-aged adults (SHYMA)John A Cowan
Department of Neurosurgery, Baltimore, MD, USA
Neurol Res 27:540-7. 2005..Despite the subtlety of clinical signs, CSF diversion treatment is effective at resolving symptomatology...
Recurrent lumbar disc herniation after single-level lumbar discectomy: incidence and health care cost analysisGiannina L Garcés Ambrossi
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurosurgery 65:574-8; discussion 578. 2009..We set out to identify the incidence and health care cost of same-level recurrent disc herniation after single-level lumbar discectomy at our institution...
Effect of antibiotic-impregnated shunt catheters in decreasing the incidence of shunt infection in the treatment of hydrocephalusDaniel M Sciubba
Department of Neurosurgery and Division of Pediatric Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Neurosurg 103:131-6. 2005..The AIS system used is an effective instrument to prevent perioperative colonization of CSF shunt components...
3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors reduce the risk of perioperative stroke and mortality after carotid endarterectomyMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
J Vasc Surg 42:829-36; discussion 836-7. 2005..20 [0.04-0.99]; P < .05). CONCLUSIONS: These data suggest that perioperative statin use may reduce the incidence of cerebrovascular events and mortality among patients undergoing CEA...
The use of ventriculoperitoneal shunts for uncontrollable intracranial hypertension without ventriculomegally secondary to HIV-associated cryptococcal meningitisGraeme F Woodworth
Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Surg Neurol 63:529-31; discussion 531-2. 2005....
Evaluation of a distal pericallosal aneurysm visualized with 3-dimensional digital subtraction angiography: case report and treatment implicationsGraeme F Woodworth
Department of Neurosurgery, Division of Interventional Neuroradiology, Johns Hopkins School of Medicine, 1017 S Bouldin Street, Baltimore, MD 21224, USA
Surg Neurol 64:321-4. 2005..This was then revealed to be a saccular bifurcation aneurysm by 3D-DSA. This additional information changed the treatment plan for this patient from medical management to a surgical approach...
Radiographic and clinical evaluation of free-hand placement of C-2 pedicle screws. Clinical articleDaniel M Sciubba
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Neurosurg Spine 11:15-22. 2009..The authors describe how, after meticulous dissection of the C-2 pars interarticularis, such screws can be placed accurately and safely without the use of fluoroscopy...
Cerebrospinal fluid drainage and dynamics in the diagnosis of normal pressure hydrocephalusGraeme F Woodworth
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurosurgery 64:919-25; discussion 925-6. 2009..We examined the utility of CSF drainage and CSF pressure (Pcsf) dynamics in predicting response to CSF shunting for patients with INPH...
Predictors of ambulatory function after decompressive surgery for metastatic epidural spinal cord compressionKaisorn L Chaichana
Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA
Neurosurgery 62:683-92; discussion 683-92. 2008..This study was designed to explore associations with maintaining and regaining ambulatory function after decompressive surgery for MESCC...
Evaluation of factors associated with postoperative infection following sacral tumor resectionDaniel M Sciubba
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Neurosurg Spine 9:593-9. 2008..To identify potential risk factors, a review of clinical outcomes for sacral tumor resections over the past 5 years at a single institution was completed, paying special attention to procedure-related complications...
Selective versus routine intraoperative shunting during carotid endarterectomy: a multivariate outcome analysisGraeme F Woodworth
Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA
Neurosurgery 61:1170-6; discussion 1176-7. 2007..No studies have assessed the independent association of selective versus routine intraluminal shunting to outcomes after CEA...
Factors contributing to the medical costs of cerebrospinal fluid shunt infection treatment in pediatric patients with standard shunt components compared with those in patients with antibiotic impregnated componentsDaniel M Sciubba
Department of Neurosurgery, Baltimore, Maryland 21287, USA
Neurosurg Focus 22:E9. 2007....
Predictors of ambulatory function after surgical resection of intramedullary spinal cord tumorsGraeme F Woodworth
Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurosurgery 61:99-105; discussion 105-6. 2007..Although previous research is limited, identifying reliable predictors of functional status after tumor resection would be clinically useful for perioperative modification strategies...
Diagnosis and management of sacral tumorsDaniel M Sciubba
Department of Neurosurgery, Johns Hopkins University, Baltimore, Maryland 21287, USA
J Neurosurg Spine 10:244-56. 2009..Special attention is given to the specific anatomical constraints that make tumors in this region of the spine more difficult to effectively manage than those in the mobile portions of the spine...
Prolonged exposure to antibiotic-impregnated shunt catheters does not increase incidence of late shunt infectionsDaniel M Sciubba
Department of Neurosurgery, Johns Hopkins School of Medicine, 600 North Wolfe Street, Meyer 8 161, Baltimore MD 21287, USA
Childs Nerv Syst 23:867-71. 2007..In this study, the authors evaluate the incidence of late shunt infection after the introduction of an AIS system in a pediatric hydrocephalus population...
Frameless stereotactic ventricular shunt placement for idiopathic intracranial hypertensionGraeme F Woodworth
The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Stereotact Funct Neurosurg 83:12-6. 2005..Placing ventricular shunts using image-guided stereotaxis in patients with IIH despite the absence of ventriculomegaly is an effective, safe treatment option...
Surgical experience in 130 pediatric patients with Chiari I malformationsR Shane Tubbs
Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Neurosurg 99:291-6. 2003..The aim of this study was to present the long-term findings of a surgical series of pediatric patients with Chiari I malformations...
Cerebrospinal fluid shunt placement for pseudotumor cerebri-associated intractable headache: predictors of treatment response and an analysis of long-term outcomesMatthew J McGirt
Departments of Neurosurgery, Ophthalmology, and Neurology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Neurosurg 101:627-32. 2004..Using ventricular shunts in patients with papilledema or symptoms lasting less than 2 years should be considered for those with pseudotumor cerebri-associated intractable headache...
Leukocytosis as an independent risk factor for cerebral vasospasm following aneurysmal subarachnoid hemorrhageMatthew J McGirt
Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
J Neurosurg 98:1222-6. 2003..Monitoring of the serum leukocyte count may allow for early diagnosis and treatment of vasospasm...
Comparison of revision rates following endoscopically versus nonendoscopically placed ventricular shunt cathetersAlan T Villavicencio
Pediatric Neurosurgery Service, Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina 27710, USA
Surg Neurol 59:375-9; discussion 379-80. 2003..42 (0.78-2.61)]. CONCLUSIONS: Endoscopic assisted ventricular catheter placement decreased the odds of proximal obstruction but failed to improve overall shunt survival in this 6 year experience...
Successful aqueductal plasty and stenting for tectal plate tumor after failed third ventriculostomy: a case reportKetan R Bulsara
Pediatric Neurosurgery Service, Division of Neurosurgery, Duke University Medical Center, Durham, NC 27705, USA
Surg Neurol 59:58-61; discussion 61-2. 2003..She has been symptom-free for 1 year. CONCLUSION: Aqueductal plasty with stenting may be an alternative to CSF shunts in some patients with hydrocephalus because of aqueductal compression resulting from tectal tumors...
Prognostic value of magnetic resonance imaging-guided stereotactic biopsy in the evaluation of recurrent malignant astrocytoma compared with a lesion due to radiation effectMatthew J McGirt
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
J Neurosurg 98:14-20. 2003..In patients who presented earlier than 5 months after radiotherapy, radiation effect on biopsy was not associated with an improved rate of survival compared with that in patients harboring recurrent malignant astrocytoma...
Comparison of total versus partial revision of initial ventriculoperitoneal shunt failuresMatthew J McGirt
Pediatric Neurosurgery Service, Division of Neurosurgery, Duke University Medical Center, Durham, N.C. 27710, USA
Pediatr Neurosurg 38:34-40. 2003..Total revision was not associated with improved shunt survival in patients with IVH...
Simvastatin increases endothelial nitric oxide synthase and ameliorates cerebral vasospasm resulting from subarachnoid hemorrhageMatthew J McGirt
Multidisciplinary Neuroprotection Laboratories, Duke University Medical Center, Duke University School of Medicine Duke University Medical Center, Durham, NC, USA
Stroke 33:2950-6. 2002..CONCLUSIONS: Simvastatin treatment before or after SAH attenuated cerebral vasospasm and neurological deficits in mice. The mechanism may be attributable in part to eNOS upregulation...
Mouse model of subarachnoid hemorrhage associated cerebral vasospasm: methodological analysisAugusto Parra
Department of Medicine-Neurology, Duke University Medical Center, Durham, NC 27710, USA
Neurol Res 24:510-6. 2002..This allows measurement of both anatomical and clinical DCV in the mouse...
Cerebrospinal fluid shunt survival and etiology of failures: a seven-year institutional experienceMatthew J McGirt
Pediatric Neurosurgery Service, Division of Neurosurgery, Duke University Medical Center, Durham, NC 27710, USA
Pediatr Neurosurg 36:248-55. 2002..Shunt life span remains poorer in shunt revisions and in younger patients. Patient characteristics may suggest a specific risk and mechanism of failure, aiding in the long-term management of shunted hydrocephalus...
