Barbara K Martin

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. ncbi request reprint Double placebo design in a prevention trial for Alzheimer's disease
    Barbara K Martin
    Department of Epidemiology, Center for Clinical Trials, Bloomberg School of Hygiene and Public Health, The Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Control Clin Trials 23:93-9. 2002
  2. ncbi request reprint Change over time in incidence of ganciclovir resistance in patients with cytomegalovirus retinitis
    Barbara K Martin
    Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    Clin Infect Dis 44:1001-8. 2007
  3. ncbi request reprint Design of Depression in Alzheimer's Disease Study-2
    Barbara K Martin
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Geriatr Psychiatry 14:920-30. 2006
  4. ncbi request reprint Quality of life in a clinical trial of highly active antiretroviral therapy alone or with intravenous or subcutaneous interleukin-2 administration
    Barbara K Martin
    The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 40:428-33. 2005
  5. ncbi request reprint Detection of ganciclovir resistance in patients with AIDS and cytomegalovirus retinitis: correlation of genotypic methods with viral phenotype and clinical outcome
    Douglas A Jabs
    Department of Ophthalmology, School of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
    J Infect Dis 193:1728-37. 2006
  6. pmc Cognitive outcomes after sertaline treatment in patients with depression of Alzheimer disease
    Cynthia A Munro
    Johns Hopkins School of Medicine, Baltimore, MD, USA
    Am J Geriatr Psychiatry 20:1036-44. 2012
  7. pmc Do treatment effects vary among differing baseline depression criteria in depression in Alzheimer's disease study ± 2 (DIADS-2)?
    Lea T Drye
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Int J Geriatr Psychiatry 26:573-83. 2011
  8. ncbi request reprint Cytomegalovirus (CMV) blood DNA load, CMV retinitis progression, and occurrence of resistant CMV in patients with CMV retinitis
    Douglas A Jabs
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Infect Dis 192:640-9. 2005
  9. ncbi request reprint Cytomegalovirus resistance to ganciclovir and clinical outcomes of patients with cytomegalovirus retinitis
    Douglas A Jabs
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Ophthalmol 135:26-34. 2003
  10. pmc Sertraline for the treatment of depression in Alzheimer disease
    Paul B Rosenberg
    Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Geriatr Psychiatry 18:136-45. 2010

Research Grants

  1. Depression in Alzheimer's Disease-II
    Curtis Meinert; Fiscal Year: 2007

Detail Information

Publications23

  1. ncbi request reprint Double placebo design in a prevention trial for Alzheimer's disease
    Barbara K Martin
    Department of Epidemiology, Center for Clinical Trials, Bloomberg School of Hygiene and Public Health, The Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Control Clin Trials 23:93-9. 2002
    ..The authors outline the placebo designs considered in ADAPT, discuss their advantages and disadvantages, and provide their rationale for and the consequences of the selection of the double placebo design...
  2. ncbi request reprint Change over time in incidence of ganciclovir resistance in patients with cytomegalovirus retinitis
    Barbara K Martin
    Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    Clin Infect Dis 44:1001-8. 2007
    ..In the mid-1990s, the incidence of cytomegalovirus (CMV) resistance to ganciclovir was estimated to be approximately 25% by 1 year after diagnosis of retinitis in patients with acquired immunodeficiency syndrome...
  3. ncbi request reprint Design of Depression in Alzheimer's Disease Study-2
    Barbara K Martin
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Geriatr Psychiatry 14:920-30. 2006
    ....
  4. ncbi request reprint Quality of life in a clinical trial of highly active antiretroviral therapy alone or with intravenous or subcutaneous interleukin-2 administration
    Barbara K Martin
    The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 40:428-33. 2005
    ..To assess the impact of subcutaneous and intravenous interleukin-2 (IL-2) on health-related quality of life (HRQOL) in adults with HIV-1 receiving highly active antiretroviral therapy (HAART)...
  5. ncbi request reprint Detection of ganciclovir resistance in patients with AIDS and cytomegalovirus retinitis: correlation of genotypic methods with viral phenotype and clinical outcome
    Douglas A Jabs
    Department of Ophthalmology, School of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
    J Infect Dis 193:1728-37. 2006
    ..The cytomegalovirus (CMV) UL97 gene can be sequenced either from blood specimens directly amplified by polymerase chain reaction (PCR) or from culture isolates, to detect resistance to ganciclovir...
  6. pmc Cognitive outcomes after sertaline treatment in patients with depression of Alzheimer disease
    Cynthia A Munro
    Johns Hopkins School of Medicine, Baltimore, MD, USA
    Am J Geriatr Psychiatry 20:1036-44. 2012
    ..The authors report cognitive outcomes in patients with depression of AD (dAD) after a 24-week trial of sertraline or placebo...
  7. pmc Do treatment effects vary among differing baseline depression criteria in depression in Alzheimer's disease study ± 2 (DIADS-2)?
    Lea T Drye
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Int J Geriatr Psychiatry 26:573-83. 2011
    ..To determine if the effect of sertraline in the depression in Alzheimer's disease study - 2 (DIADS-2) differed in subgroups of patients defined by baseline depression criteria...
  8. ncbi request reprint Cytomegalovirus (CMV) blood DNA load, CMV retinitis progression, and occurrence of resistant CMV in patients with CMV retinitis
    Douglas A Jabs
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Infect Dis 192:640-9. 2005
    ..CMV load has limited clinical utility, because of its low positive predictive value. Its high negative predictive value for occurrence of resistant CMV suggests that it may have utility as a screening tool to exclude resistance...
  9. ncbi request reprint Cytomegalovirus resistance to ganciclovir and clinical outcomes of patients with cytomegalovirus retinitis
    Douglas A Jabs
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Ophthalmol 135:26-34. 2003
    ..To evaluate whether cytomegalovirus resistant to ganciclovir, detected in either the blood or urine, correlates with adverse ocular outcomes...
  10. pmc Sertraline for the treatment of depression in Alzheimer disease
    Paul B Rosenberg
    Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Geriatr Psychiatry 18:136-45. 2010
    ..The authors conducted a multicenter, randomized, placebo-controlled trial titled "Depression in Alzheimer's Disease-2" to assess the efficacy and tolerability of sertraline for depression in AD...
  11. pmc Sertraline for the treatment of depression in Alzheimer disease: genetic influences
    Matthew E Peters
    The Johns Hopkins University, Baltimore, MD 21224, USA
    J Geriatr Psychiatry Neurol 24:222-8. 2011
    ..Treatment response by genotype was measured by (1) the modified Alzheimer's Disease Cooperative Study Clinical Global Impression of Change, (2) the Cornell scale for Depression in Dementia, and (3) remission of depression...
  12. pmc Evaluation of the United States public health service guidelines for discontinuation of anticytomegalovirus therapy after immune recovery in patients with cytomegalovirus retinitis
    Janet T Holbrook
    Center for Clinical Trials, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21232, USA
    Am J Ophthalmol 152:628-637.e1. 2011
    ....
  13. ncbi request reprint Clinical application of operationalized criteria for 'Depression of Alzheimer's Disease'
    Paul B Rosenberg
    Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Int J Geriatr Psychiatry 20:119-27. 2005
    ..Criteria for the diagnosis of dAD have been proposed previously...
  14. ncbi request reprint The effect of cytomegalovirus retinitis on the quality of life of patients with AIDS in the era of highly active antiretroviral therapy
    John H Kempen
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ophthalmology 110:987-95. 2003
    ..To evaluate the effect of cytomegalovirus (CMV) retinitis on quality of life (QOL) in patients with the acquired immune deficiency syndrome (AIDS)...
  15. ncbi request reprint Comparison of cytomegalovirus (CMV) UL97 gene sequences in the blood and vitreous of patients with acquired immunodeficiency syndrome and CMV retinitis
    Huiling Hu
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Infect Dis 185:861-7. 2002
    ..Although the number of mutations limits definitive interpretation, these data suggest that blood specimens may reflect the events occurring in the eyes of patients with CMV retinitis...
  16. ncbi request reprint The impact of anemia on energy and physical functioning in individuals with AIDS
    Richard D Semba
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Arch Intern Med 165:2229-36. 2005
    ..To our knowledge, the relationship between changes in hemoglobin level and energy and physical functioning in the anemic and "normal" ranges of hemoglobin among individuals with AIDS has not been well characterized...
  17. ncbi request reprint The trialist, meta-analyst, and journal editor: lessons from ADAPT
    Barbara K Martin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Med 120:192-3. 2007
  18. ncbi request reprint Experience Corps: a dual trial to promote the health of older adults and children's academic success
    Linda P Fried
    Mailman School of Public Health, Columbia University, New York, NY, USA
    Contemp Clin Trials 36:1-13. 2013
    ..This trial evaluates (1) whether senior volunteer roles within Experience Corps™ beneficially impact children's academic achievement and classroom behavior in public elementary schools and (2) impact on the health of volunteers...
  19. pmc Excess mortality in patients with AIDS in the era of highly active antiretroviral therapy: temporal changes and risk factors
    Milo A Puhan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Clin Infect Dis 51:947-56. 2010
    ..We assessed temporal changes in excess mortality and elucidated risk factors for excess mortality in patients with AIDS diagnosed in the era of highly active antiretroviral therapy (HAART)...
  20. ncbi request reprint H2 histamine receptor blockade in the treatment of Alzheimer disease: a randomized, double-blind, placebo-controlled trial of nizatidine
    Michelle C Carlson
    Department of Mental Hygiene, and Center on Aging and Health, The Johns Hopkins University School of Public Health, Baltimore, Maryland 21205, USA
    Alzheimer Dis Assoc Disord 16:24-30. 2002
    ..To evaluate the efficacy of nizatidine, a histamine H2-blocking drug, in delaying the progression of cognitive impairment in older adults with Alzheimer disease (AD)...
  21. ncbi request reprint Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis
    Adriana Weinberg
    University of Colorado Health Sciences Center, Denver, Colorado, USA
    J Infect Dis 187:777-84. 2003
    ..016). The incidence of foscarnet resistance after 6, 9, and 12 months of therapy was 13%, 24%, and 37%, respectively...
  22. ncbi request reprint Comparability of two fundus photograph reading centers in grading cytomegalovirus retinitis progression
    Larry D Hubbard
    Department of Ophthalmology and Visual Sciences, The University of Wisconsin Medical School, Madison Wisconsin 53711 1068, USA
    Am J Ophthalmol 137:426-34. 2004
    ..To compare grading of cytomegalovirus retinitis progression by two different fundus photograph reading centers (FPRCs)...
  23. pmc Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib
    Barbara K Martin
    Arch Neurol 65:896-905. 2008
    ..Observational studies have shown reduced risk of Alzheimer dementia in users of nonsteroidal anti-inflammatory drugs...

Research Grants1

  1. Depression in Alzheimer's Disease-II
    Curtis Meinert; Fiscal Year: 2007
    ..The predictive validity of defining depression in AD using a symptom scale or each of these syndromes will be assessed longitudinally against the various study outcomes, and against efficacy of response to antidepressant treatment. ..