Research Topics
Genomes and Genes | ANDREW L MAMMENSummaryAffiliation: Johns Hopkins University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Autoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathyANDREW L MAMMEN
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Arthritis Rheum 63:713-21. 2011..The purpose of this study was to identify these molecules to help clarify the disease mechanism and facilitate diagnosis...
Increased frequency of DRB1*11:01 in anti-hydroxymethylglutaryl-coenzyme A reductase-associated autoimmune myopathyANDREW L MAMMEN
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Arthritis Care Res (Hoboken) 64:1233-7. 2012..To investigate the association of anti-hydroxymethylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy with HLA class I and II antigens...
Expression of the dermatomyositis autoantigen Mi-2 in regenerating muscleANDREW L MAMMEN
Johns Hopkins Bayview, Johns Hopkins Myositis Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
Arthritis Rheum 60:3784-93. 2009..This study was undertaken to define the population of cells expressing high levels of Mi-2 in DM muscle and to explore the regulation and functional role of Mi-2 during muscle regeneration...
Dermatomyositis and polymyositis: Clinical presentation, autoantibodies, and pathogenesisANDREW L MAMMEN
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Ann N Y Acad Sci 1184:134-53. 2010....
Autoimmune myopathies: autoantibodies, phenotypes and pathogenesisANDREW L MAMMEN
Department of Neurology, Johns Hopkins Bayview Medical Center, Johns Hopkins Myositis Center, Mason F Lord Building Center Tower, Suite 4500, Baltimore, MD 21224, USA USA
Nat Rev Neurol 7:343-54. 2011..The contribution of interferon signaling to the development of dermatomyositis and the potential link between malignancies and the initiation of autoimmune myopathies are also assessed...
Rarity of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies in statin users, including those with self-limited musculoskeletal side effectsANDREW L MAMMEN
Johns Hopkins University, Baltimore, Maryland, USA
Arthritis Care Res (Hoboken) 64:269-72. 2012..The current work assessed the prevalence of anti-HMGCR antibodies in these groups of statin users...
Antibody levels correlate with creatine kinase levels and strength in anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase-associated autoimmune myopathyJessie L Werner
Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
Arthritis Rheum 64:4087-93. 2012..The main objective of this study was to define the association of anti-HMGCR antibody levels with disease activity...
A novel autoantibody recognizing 200-kd and 100-kd proteins is associated with an immune-mediated necrotizing myopathyLisa Christopher-Stine
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Arthritis Rheum 62:2757-66. 2010..The aim of this study was to identify novel autoantibodies in patients with necrotizing myopathy...
Isolated elevation of aldolase in the serum of myositis patients: a potential biomarker of damaged early regenerating muscle cellsLivia Casciola-Rosen
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Clin Exp Rheumatol 30:548-53. 2012..Elevated serum aldolase A levels occur in the absence of elevated creatine kinase M (CK) levels in a subset of myositis patients. This study was undertaken to investigate the cell biology of this unexplained clinical observation...
Myositis autoantibodiesLivia Casciola-Rosen
Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21224, USA
Curr Opin Rheumatol 24:602-8. 2012..To review recent advances in our understanding of autoantibodies associated with dermatomyositis and the autoimmune necrotizing myopathies...
Magnetic resonance imaging of inflammatory myopathiesFilippo Del Grande
Russell H Morgan Department of Radiology and Radiological Science, School of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA
Top Magn Reson Imaging 22:39-43. 2011..Lastly, we provide an overview about some advanced MRI techniques that focus more on function than on morphology of muscle...
A novel conserved isoform of the ubiquitin ligase UFD2a/UBE4B is expressed exclusively in mature striated muscle cellsANDREW L MAMMEN
Johns Hopkins University School of Medicine, Department of Medicine, Division of Rheumatology, Baltimore, Maryland, United States of America
PLoS ONE 6:e28861. 2011..We conclude that the regulated expression of these UFD2a isoforms most likely imparts divergent functions that are important for myogenisis...
Expanding the spectrum of monoclonal light chain deposition disease in muscleLyle W Ostrow
Department of Neurology, Johns Hopkins School of Medicine, 733 N Broadway, Baltimore, Maryland 21205, USA
Muscle Nerve 45:755-61. 2012..The diagnosis of amyloid myopathy is delayed when monoclonal gammopathies are not detected on initial testing and muscle biopsies are nondiagnostic, and the EMG and symptoms can mimic an inflammatory myopathy...
Statin myopathy: a review of recent progressANDREW L MAMMEN
Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Curr Opin Rheumatol 22:644-50. 2010..However, they can have myotoxic effects ranging in severity from myalgias to rhabdomyolysis. This review focuses on recent progress in defining the clinical features and mechanism(s) of statin-induced myopathy...
