J A Mahoney

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Cloning and characterization of CPVL, a novel serine carboxypeptidase, from human macrophages
    J A Mahoney
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, United Kingdom
    Genomics 72:243-51. 2001
  2. ncbi The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis
    James A Mahoney
    Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Biochem J 361:587-95. 2002
  3. ncbi Recurrent transverse myelitis associates with anti-Ro (SSA) autoantibodies
    L K Hummers
    Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Neurology 62:147-9. 2004
  4. ncbi Soluble CD154 is not associated with atherosclerosis in systemic lupus erythematosus
    Adnan Kiani
    Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland 20852, USA
    J Rheumatol 34:969-72. 2007
  5. ncbi The MPAC domain is a novel mitotically regulated domain, removed by apoptotic protease cleavage during cell death
    Sarah Spinette
    Department of Medicine, Division of Rheumatology, Johns Hopkins University, Baltimore, MD, USA
    Biochem Biophys Res Commun 347:1103-12. 2006
  6. ncbi Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase
    Lance Wells
    Department of Biological Chemistry and Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    J Biol Chem 277:1755-61. 2002
  7. ncbi Ufd2, a novel autoantigen in scleroderma, regulates sister chromatid separation
    Sarah Spinette
    Department of Medicine Division of Rheumatology Johns Hopkins University, Baltimore, Maryland 21224, USA
    Cell Cycle 3:1638-44. 2004
  8. ncbi Asymmetric dimethylarginine is a marker of poor prognosis and coronary calcium in systemic lupus erythematosus
    Adnan N Kiani
    Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Rheumatol 34:1502-5. 2007
  9. ncbi A vitellogenic-like carboxypeptidase expressed by human macrophages is localized in endoplasmic reticulum and membrane ruffles
    James Harris
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Int J Exp Pathol 87:29-39. 2006
  10. ncbi Immunophenotyping of macrophages in human pulmonary tuberculosis and sarcoidosis
    Lee-Anne Stanton
    Department of Medical Biochemistry, Tygerberg Medical School University of Stellenbosch, Tygerberg, South Africa
    Int J Exp Pathol 84:289-304. 2003

Collaborators

Detail Information

Publications10

  1. ncbi Cloning and characterization of CPVL, a novel serine carboxypeptidase, from human macrophages
    J A Mahoney
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, United Kingdom
    Genomics 72:243-51. 2001
    ..Possible functions for CPVL in macrophages include digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation...
  2. ncbi The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis
    James A Mahoney
    Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Biochem J 361:587-95. 2002
    ..Cleavage of UFD2 by caspases or granzyme B within this putative regulatory N-terminal domain might have important functional consequences within the apoptotic cascade...
  3. ncbi Recurrent transverse myelitis associates with anti-Ro (SSA) autoantibodies
    L K Hummers
    Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Neurology 62:147-9. 2004
    ..Antibodies to 52-kd Ro were demonstrated in 77% of cases (10/13) compared with only 33% of control subjects (4/12)...
  4. ncbi Soluble CD154 is not associated with atherosclerosis in systemic lupus erythematosus
    Adnan Kiani
    Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland 20852, USA
    J Rheumatol 34:969-72. 2007
    ..We determined the association of sCD154 with coronary calcium and carotid plaque at the baseline visit of the Lupus Atherosclerosis Prevention Study...
  5. ncbi The MPAC domain is a novel mitotically regulated domain, removed by apoptotic protease cleavage during cell death
    Sarah Spinette
    Department of Medicine, Division of Rheumatology, Johns Hopkins University, Baltimore, MD, USA
    Biochem Biophys Res Commun 347:1103-12. 2006
    ....
  6. ncbi Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase
    Lance Wells
    Department of Biological Chemistry and Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    J Biol Chem 277:1755-61. 2002
    ..These studies support the identification of this protein as an O-GlcNAcase and identify important interactions and modifications that may regulate the enzyme and O-GlcNAc cycling...
  7. ncbi Ufd2, a novel autoantigen in scleroderma, regulates sister chromatid separation
    Sarah Spinette
    Department of Medicine Division of Rheumatology Johns Hopkins University, Baltimore, Maryland 21224, USA
    Cell Cycle 3:1638-44. 2004
    ..Its targeting in scleroderma, together with many other components of the mitotic machinery, reinforces the concept that mitotic cells may be an important focus of the autoimmune response in this disease...
  8. ncbi Asymmetric dimethylarginine is a marker of poor prognosis and coronary calcium in systemic lupus erythematosus
    Adnan N Kiani
    Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Rheumatol 34:1502-5. 2007
    ..To determine the association of serum asymmetric dimethylarginine (ADMA) with clinical features, laboratory tests, treatment, cardiovascular risk factors, and subclinical atherosclerosis in patients with systemic lupus erythematosus (SLE)...
  9. ncbi A vitellogenic-like carboxypeptidase expressed by human macrophages is localized in endoplasmic reticulum and membrane ruffles
    James Harris
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Int J Exp Pathol 87:29-39. 2006
    ..We propose that CPVL may be involved in antigen processing, the secretory pathway and/or in actin remodelling and lamellipodium formation...
  10. ncbi Immunophenotyping of macrophages in human pulmonary tuberculosis and sarcoidosis
    Lee-Anne Stanton
    Department of Medical Biochemistry, Tygerberg Medical School University of Stellenbosch, Tygerberg, South Africa
    Int J Exp Pathol 84:289-304. 2003
    ..These studies provide new marker antigens and extend previous studies on MØ differentiation, activation and local interactions in chronic human granulomatous inflammation in the lung...