DEAN FREDERICK MACKINNON

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Rapid switching of mood in families with multiple cases of bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Arch Gen Psychiatry 60:921-8. 2003
  2. ncbi request reprint Association of rapid mood switching with panic disorder and familial panic risk in familial bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Meyer 3 181, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Am J Psychiatry 160:1696-8. 2003
  3. ncbi request reprint Rapid mood switching and suicidality in familial bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Bipolar Disord 7:441-8. 2005
  4. ncbi request reprint Affective instability as rapid cycling: theoretical and clinical implications for borderline personality and bipolar spectrum disorders
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Bipolar Disord 8:1-14. 2006
  5. pmc Carbon dioxide provocation of anxiety and respiratory response in bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
    J Affect Disord 99:45-9. 2007
  6. ncbi request reprint Panic comorbidity with bipolar disorder: what is the manic-panic connection?
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Meyer 3 181, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Bipolar Disord 8:648-64. 2006
  7. doi request reprint Carbon dioxide induces erratic respiratory responses in bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore Maryland, USA
    J Affect Disord 112:193-200. 2009
  8. doi request reprint Bipolar disorder as maladaptive arousal: a behavioral model and evidence
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Meyer 3 181, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Ann N Y Acad Sci 1129:185-9. 2008

Research Grants

Detail Information

Publications8

  1. ncbi request reprint Rapid switching of mood in families with multiple cases of bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Arch Gen Psychiatry 60:921-8. 2003
    ..Phenomena in the bipolar spectrum, including rapid cycling, cyclothymia, and affective instability of borderline personality, may be important markers of etiologic heterogeneity. Rapid switching of mood may be central to these phenomena...
  2. ncbi request reprint Association of rapid mood switching with panic disorder and familial panic risk in familial bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Meyer 3 181, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Am J Psychiatry 160:1696-8. 2003
    ..The authors investigated whether comorbidity of bipolar disorder and panic disorder is associated with rapid mood switching in families with a high rate of bipolar disorder...
  3. ncbi request reprint Rapid mood switching and suicidality in familial bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Bipolar Disord 7:441-8. 2005
    ....
  4. ncbi request reprint Affective instability as rapid cycling: theoretical and clinical implications for borderline personality and bipolar spectrum disorders
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Bipolar Disord 8:1-14. 2006
    ....
  5. pmc Carbon dioxide provocation of anxiety and respiratory response in bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
    J Affect Disord 99:45-9. 2007
    ..Frequent bipolar/panic comorbidity implies bipolar individuals may experience CO2-provoked anxiety and changes in respiratory patterns similar to those experienced by individuals with panic disorder...
  6. ncbi request reprint Panic comorbidity with bipolar disorder: what is the manic-panic connection?
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Meyer 3 181, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Bipolar Disord 8:648-64. 2006
    ..As both are episodic disorders of affect regulation, the common pathophysiological mechanism is likely to involve deficits in amygdala-mediated, plasticity-dependent emotional conditioning...
  7. doi request reprint Carbon dioxide induces erratic respiratory responses in bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore Maryland, USA
    J Affect Disord 112:193-200. 2009
    ..Moreover, problems in the arousal and modulation of appetites are central to the clinical syndromes of mania and depression; hence CO(2) may arouse an abnormal respiratory response to "air hunger"...
  8. doi request reprint Bipolar disorder as maladaptive arousal: a behavioral model and evidence
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Meyer 3 181, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Ann N Y Acad Sci 1129:185-9. 2008
    ..If confirmed, the unstable respiratory response to CO2 may prove useful as a bipolar-disorder endophenotype...

Research Grants3

  1. Etiologic Connections of Affective and Anxiety Disorders
    Dean MacKinnon; Fiscal Year: 2006
    ..Results of this work will then be applied to ongoing genetic studies of bipolar disorder, and will inform the candidate's further research into affective and anxiety disorder etiology. ..
  2. A Collaborative Genomic Study of Bipolar Disoder
    Dean MacKinnon; Fiscal Year: 2007
    ..Analysis of the existing sib pair families plus this large set of cases and controls should permit the confirmation of several vulnerability genes during this grant period. ..