Research Topics
Genomes and Genes | Lawrence R LustigSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Cochlear implantation in patients with bilateral Ménière's syndromeLawrence R Lustig
Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland 21287, USA
Otol Neurotol 24:397-403. 2003..To evaluate the indications and clinical outcomes (audiologic and vestibular) in patients with Ménière's syndrome who have undergone cochlear implantation...
GJB2 gene mutations in cochlear implant recipients: prevalence and impact on outcomeLawrence R Lustig
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, JHOC, Baltimore, MD 21287, USA
Arch Otolaryngol Head Neck Surg 130:541-6. 2004..To determine the prevalence of GJB2 gene mutations in patients undergoing cochlear implantation (CI) and their impact on rehabilitative outcome following implantation...
Cochlear implantation in patients with neurofibromatosis type 2 and bilateral vestibular schwannomaLawrence R Lustig
Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University, Baltimore, Maryland, and Department of Otolaryngology Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA
Otol Neurotol 27:512-8. 2006..To investigate the results of cochlear implantation in patients with neurofibromatosis Type 2 (NF2) and bilateral vestibular schwannoma...
External magnet displacement in cochlear implants: causes and managementDavid Posner
Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, San Francisco, California 94143 0342, USA
Otol Neurotol 31:88-93. 2010..To evaluate the complication of external magnet displacement in cochlear implant patients...
Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapyOmar Akil
Department of Otolaryngology, Head and Neck Surgery, University of California San Francisco, San Francisco, CA 94143, USA
Neuron 75:283-93. 2012..These findings represent a successful restoration of hearing by gene replacement in mice, which is a significant advance toward gene therapy of human deafness...
Dehiscence of bone overlying the superior canal as a cause of apparent conductive hearing lossLloyd B Minor
Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Otol Neurotol 24:270-8. 2003..To identify patients with superior semicircular canal dehiscence and apparent conductive hearing loss and to define the cause of the air-bone gap...
Venous malformations of the temporal bone are a common feature in CHARGE syndromeDavid R Friedmann
Department of Otolaryngology, New York University School of Medicine, New York, New York 10032, USA
Laryngoscope 122:895-900. 2012..Recent experience with venous malformations during cochlear implant surgery prompted this study to define the spectrum of venous abnormalities in CHARGE and their surgical implications in otology...
Cochlear gene therapyLawrence R Lustig
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, San Francisco, California 94115, USA
Curr Opin Neurol 25:57-60. 2012....
Expansile bone cyst and cholesteatoma of the temporal boneHarry S Hwang
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, California, USA
Otol Neurotol 30:170-3. 2009..To identify primary bony cysts of the temporal bone...
Paget's disease and fibrous dysplasiaTimothy E Hullar
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, 601 North Caroline Street, Baltimore, MD, USA
Otolaryngol Clin North Am 36:707-32. 2003..As a better understanding of the etiology of these conditions develops and new pharmacotherapeutic agents are tested, it is likely that physicians will be able to turn to medical rather than surgical techniques to treat these disorders...
A randomized, double-blind, placebo-controlled clinical study to assess safety and clinical activity of OTO-104 given as a single intratympanic injection in patients with unilateral Ménière's diseasePaul R Lambert
Medical University of South Carolina, Department of Otolaryngology, Charleston, South Carolina, USA
Otol Neurotol 33:1257-65. 2012..To evaluate the safety, tolerability, and clinical activity of a single intratympanic injection of OTO-104, sustained-release dexamethasone formulation, in patients with unilateral Ménière's disease...
Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner earAbdullah A Osman
Department of Otolaryngology, Washington University School of Medicine, 660 South Euclid Ave, St Louis MO 63110, USA
Mol Cell Neurosci 38:153-69. 2008..Our data suggest that RIC-3 facilitates receptor function, while rapsyn enhances receptor clustering at the cell surface...
Comparison of the bone anchored hearing aid implantable hearing device with contralateral routing of offside signal amplification in the rehabilitation of unilateral deafnessJohn K Niparko
Department of Otolaryngology Head and Neck Surgery, Baltimore, MD 21287 0910, USA
Otol Neurotol 24:73-8. 2003....
Progressive deafness and altered cochlear innervation in knock-out mice lacking prosaposinOmar Akil
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, San Francisco, California 94143 0449, USA
J Neurosci 26:13076-88. 2006..Furthermore, prosaposin's overlapping developmental expression pattern and binding capacity toward the nAChR alpha10 suggest that alpha10 may also play a role in this function...
Hearing loss and the invention of the phonograph: the story of Thomas Alva EdisonCharles J Limb
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Otol Neurotol 23:96-101. 2002
Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3Rebecca P Seal
Department of Physiology, School of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
Neuron 57:263-75. 2008..The glutamate release conferred by expression of VGLUT3 thus has an essential role in both function and development of the auditory pathway, as well as in the control of cortical excitability...
Restoration of brain stem auditory-evoked potential in maple syrup urine diseaseChristopher Spankovich
University of California San Francisco, San Francisco, California, USA
Otol Neurotol 28:566-9. 2007..The possible mechanism of the hearing loss and reversibility of wave I is proposed...
