Research Topics
| Orin S LevineSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
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Detail Information
Publications
The Pneumonia Etiology Research for Child Health Project: a 21st century childhood pneumonia etiology studyOrin S Levine
Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Clin Infect Dis 54:S93-101. 2012..PERCH will also address differences in host, environmental, and/or geographic factors that might determine pneumonia etiology and, by preserving specimens, will generate a resource for future research and pathogen discovery...- Sequelae due to bacterial meningitis among African children: a systematic literature reviewMeenakshi Ramakrishnan
BMC Med 7:47. 2009..The objective of this study is to present a comprehensive review of data on bacterial meningitis sequelae in children from the African continent... 
Global status of Haemophilus influenzae type b and pneumococcal conjugate vaccines: evidence, policies, and introductionsOrin S Levine
Department of International Health, Johns Hopkins Bloomberg School of Public Health, International Vaccine Access Center, Baltimore, Maryland, USA
Curr Opin Infect Dis 23:236-41. 2010..This study reviews the status of vaccine use globally and the evidence base that supports policy recommendations for use of these vaccines in children...- A policy framework for accelerating adoption of new vaccinesOrin S Levine
International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Hum Vaccin 6:1021-4. 2010..It highlights the important roles of different actors at various times in the process and may allow new vaccine initiatives to save time and improve their efficiency by anticipating key steps and actions... 
Pneumococcal vaccination and public healthOrin S Levine
GAVI's PneumoADIP, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Lancet 369:1144-5. 2007- The future of immunisation policy, implementation, and financingOrin S Levine
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Lancet 378:439-48. 2011..Novel methods are needed to finance the increasing number of new vaccines that have the potential to save lives in countries that are too poor to afford them. Here, we discuss some options... - Pneumococcal vaccination in developing countriesOrin S Levine
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Lancet 367:1880-2. 2006 - PneumoADIP: an example of translational research to accelerate pneumococcal vaccination in developing countriesOrin S Levine
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Health Popul Nutr 22:268-74. 2004..This model may provide a useful example and valuable lessons for how a successful public-private partnership can improve global health... - Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimatesJames P Watt
Hib Initiative, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Lancet 374:903-11. 2009..Hib disease can be almost completely eliminated through routine vaccination. We assessed the global burden of disease to help national policy makers and international donors set priorities... - Evaluation of risk factors for severe pneumonia in children: the Pneumonia Etiology Research for Child Health studyChizoba B Wonodi
International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, USA
Clin Infect Dis 54:S124-31. 2012.... - Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimatesKatherine L O'Brien
GAVI s PneumoADIP, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Lancet 374:893-902. 2009..To support local and global policy decisions on pneumococcal disease prevention and treatment, we estimated country-specific incidence of serious cases and deaths in children younger than 5 years... - A literature review and survey of childhood pneumonia etiology studies: 2000-2010Zunera Gilani
Department of Epidemiology, Bloomberg School of Public Health, Baltimore, MD 21205, USA
Clin Infect Dis 54:S102-8. 2012..It reinforces the need for the standardization of methods and analyses for present and future pneumonia etiology studies in order to optimize their cumulative potential to accurately describe the microbial causes of childhood pneumonia... - Identification and selection of cases and controls in the Pneumonia Etiology Research for Child Health projectMaria Deloria-Knoll
International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Clin Infect Dis 54:S117-23. 2012..For each issue, we present the options that were considered, the advantages and disadvantages of each, the rationale for the methods selected for PERCH, and remaining implications and limitations... - Estimated economic benefits during the 'decade of vaccines' include treatment savings, gains in labor productivityMeghan L Stack
Department of International Health at the Johns Hopkins Bloomberg School of Public Health, in Baltimore, Maryland, USA
Health Aff (Millwood) 30:1021-8. 2011..Monetary estimates based on this type of analysis can be used to determine the return on investment in immunization from both the international community and local governments, and they should be considered in policy making... - Global reduction of Hib disease: what are the next steps? Proceedings of the meeting Scottsdale, Arizona, September 22-25, 2002James P Watt
Department of International Health, the Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
J Pediatr 143:S163-87. 2003..In areas where Hib disease burden is not well characterized, additional work will be needed to understand the epidemiology of Hib disease and to communicate the value of Hib conjugate vaccine... - Haemophilus influenzae type b conjugate vaccines: considerations for vaccination schedules and implications for developing countriesSean P Fitzwater
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Hum Vaccin 6:810-8. 2010..Here, we present a synthesis of data supporting various Hib vaccine schedules, with a focus on the implications for developing countries... - Standardizing surveillance of pneumococcal diseaseMaria Deloria Knoll
GAVI Alliance s Pneumococcal Vaccines Accelerated Development and Introduction Plan, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Clin Infect Dis 48:S37-48. 2009..To facilitate comparisons of surveillance data among countries, investigators of Pneumococcal Vaccines Accelerated Development and Introduction Plan-sponsored projects have developed standard case definitions and data reporting methods... - Spatial and socio-demographic predictors of time-to-immunization in a rural area in Kenya: Is equity attainable?Jennifer C Moïsi
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Vaccine 28:5725-30. 2010..Travel time did not affect vaccination coverage or timeliness. The Kenyan EPI reaches nearly all children in Kilifi and delays in vaccination are few, suggesting that vaccines will have maximal impact on child morbidity and mortality... - Specimen collection for the diagnosis of pediatric pneumoniaLaura L Hammitt
International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Clin Infect Dis 54:S132-9. 2012..We discuss the advantages and limitations of each specimen, and discuss the rationale for the specimens to be collected for the Pneumonia Etiology Research for Child Health study... - The evidence for using conjugate vaccines to protect HIV-infected children against pneumococcal diseaseSandra J Bliss
Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
Lancet Infect Dis 8:67-80. 2008..PCV should be considered as an important intervention for improving the lives of HIV-infected children... - Enhanced diagnosis of pneumococcal meningitis with use of the Binax NOW immunochromatographic test of Streptococcus pneumoniae antigen: a multisite studyJennifer C Moïsi
GAVI Alliance s PneumoADIP, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
Clin Infect Dis 48:S49-56. 2009..Cerebrospinal fluid (CSF) culture and latex agglutination testing are currently the standard diagnostic methods but lack sensitivity... - During the 'decade of vaccines,' the lives of 6.4 million children valued at $231 billion could be savedSachiko Ozawa
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Health Aff (Millwood) 30:1010-20. 2011..It highlights the major economic benefits made possible by improving vaccine coverage... - Geographic access to care is not a determinant of child mortality in a rural Kenyan setting with high health facility densityJennifer C Moïsi
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
BMC Public Health 10:142. 2010..Distance to health facilities is a known determinant of health care utilization and may drive inequalities in health outcomes; we aimed to investigate its effects on childhood mortality... - Cost-effectiveness and economic benefits of vaccines in low- and middle-income countries: a systematic reviewSachiko Ozawa
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States
Vaccine 31:96-108. 2012..As vaccine costs rise and competing priorities increase, economic evidence is likely to play an increasingly important role in vaccination decisions... - Sensitivity of hospital-based surveillance for severe disease: a geographic information system analysis of access to care in Kilifi district, KenyaJennifer C Moïsi
KEMRI Wellcome Trust Research Programme, Kilifi, Kenya
Bull World Health Organ 89:102-11. 2011..To explore the relationship between homestead distance to hospital and access to care and to estimate the sensitivity of hospital-based surveillance in Kilifi district, Kenya... - Higher pneumococcal disease vaccination rates needed to protect more at-risk US adultsSusan J Rehm
National Foundation for Infectious Diseases, Bethesda, MD, USA
Postgrad Med 121:101-5. 2009.... - Effectiveness of pneumococcal conjugate vaccineOrin S Levine
Center for American Indian Health, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Lancet 368:1469-70. 2006 - Pneumococcal disease and vaccination in the Americas: an agenda for accelerated vaccine introductionSalvador Garcia
The Pan American Health Organization, Washington, DC, United States of America
Rev Panam Salud Publica 19:340-8. 2006.... - The changing landscape of epidemic bacterial meningitis in Africa: new opportunities for preventionJay C Butler
J Infect Dis 192:189-91. 2005 - Impact of haemophilus influenzae type b conjugate vaccine in South Africa and ArgentinaMichael Martin
Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 23:842-7. 2004..Surrogate indicators of bacterial meningitis also declined and might be useful measures of Hib conjugate vaccine impact at hospitals where capacity to culture Hib is not available... - Pneumococcal vaccination for Indian childrenOrin S Levine
Indian Pediatr 44:491-6. 2007 - Rapid assessment tool for Haemophilus influenzae type b disease in developing countriesDaniel R Feikin
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 10:1270-6. 2004..Results were affected by the quality of available data. The Hib rapid assessment tool can be useful to countries that desire a timely assessment of Hib disease rates... - Vaccines to prevent pneumonia and improve child survivalShabir A Madhi
Department of Science and Technology, National Research Foundation, Vaccine Preventable Diseases, Chris Hani Baragwanth Hospital, University of the Witwatersrand, Bertsham, South Africa
Bull World Health Organ 86:365-72. 2008..In this review, we discuss advances made in optimizing the use of established vaccines and the potential issues related to newer bacterial conjugate vaccines in reducing childhood pneumonia morbidity and mortality...