Research Topics
| Peter O KwiterovichSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Clinical relevance of the biochemical, metabolic, and genetic factors that influence low-density lipoprotein heterogeneityPeter O Kwiterovich
Lipid Research Atherosclerosis Division, Departments of Pediatrics and Medicine, The Johns Hopkins University School of Medicine, University Lipid Clinic, Baltimore, Maryland 21205, USA
Am J Cardiol 90:30i-47i. 2002..The next critical step in further reduction of CAD will be the correct diagnosis and treatment of patients with small, dense LDL and the dyslipidemia that accompanies it...
Diagnosis and management of familial dyslipoproteinemiasPeter O Kwiterovich
Lipid Research Atherosclerosis Center, Helen Taussig Center, The Johns Hopkins University School of Medicine, David Rubenstein Building, Suite 3093, 200 N Wolfe St, Baltimore, MD, 21287, USA
Curr Cardiol Rep 15:371. 2013..The major goal is to prevent or ameliorate the major complications of many familial dyslipoproteinemias, namely, premature CVD or pancreatitis. Dietary and drug treatment specific for each inherited disorder is reviewed...- Interrelationships between the concentration and size of the largest high-density lipoprotein subfraction and apolipoprotein C-I in infants at birth and follow-up at 2-3 months of age and their parentsPeter O Kwiterovich
The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
J Clin Lipidol 7:29-37. 2013..Lipoprotein subfractions in infants may predict the risk of cardiovascular disease factors in children... - Universal screening of cholesterol in childrenPeter O Kwiterovich
Johns Hopkins University Lipid Clinic Kwiterovich, The Johns Hopkins University, Baltimore, Maryland
Clin Cardiol 35:662-4. 2012..Peter O. Kwiterovich, MD has received a research grants from Pfizer and is on the advisory board at Merck. The authors have no other funding, financial relationships, or conflicts of interest to disclose... - Effect of a high-fat ketogenic diet on plasma levels of lipids, lipoproteins, and apolipoproteins in childrenPeter O Kwiterovich
Lipid Research Atherosclerosis Division, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
JAMA 290:912-20. 2003..Little prospective long-term information is available on the effect of a ketogenic diet on plasma lipoproteins in children with difficult-to-control seizures... - Lipoprotein heterogeneity at birth: influence of gestational age and race on lipoprotein subclasses and Lp (a) lipoproteinPeter O Kwiterovich
The Johns Hopkins Medication Institutions, Baltimore, Maryland, USA
Ethn Dis 14:351-9. 2004..To determine the influence of gestational age, gender, and race, on lipoprotein heterogeneity at birth... - A large high-density lipoprotein enriched in apolipoprotein C-I: a novel biochemical marker in infants of lower birth weight and younger gestational agePeter O Kwiterovich
The Johns Hopkins Medical Institutions, Baltimore, MD, USA
JAMA 293:1891-9. 2005..Low birth weight is associated with increased cardiovascular disease in adulthood, and differences in the molecular weight, composition, and quantity of lipoprotein subclasses are associated with coronary artery disease... - Primary and secondary disorders of lipid metabolism in pediatricsPeter O Kwiterovich
Department of Pediatrics, Lipid Research Atherosclerosis Unit, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Pediatr Endocrinol Rev 5:727-38. 2008.... - Cut points for lipids and lipoproteins in children and adolescents: should they be reassessed?Peter O Kwiterovich
The Johns Hopkins Medical Institutions, Department of Pediatrics, Baltimore MD 21205, USA
Clin Chem 54:1113-5. 2008 - Recognition and management of dyslipidemia in children and adolescentsPeter O Kwiterovich
Lipid Research Atherosclerosis Division, Department of Pediatrics, The Johns Hopkins Medical Institutions, 550 North Broadway, Suite 310, Baltimore, Maryland 21205, USA
J Clin Endocrinol Metab 93:4200-9. 2008..Cardiovascular disease (CVD) remains the number one cause of death in the United States. The origins of atherosclerosis and CVD begin in childhood. Dyslipidemia and obesity are endemic in American youth and require urgent action... - Response of obligate heterozygotes for phytosterolemia to a low-fat diet and to a plant sterol ester dietary challengePeter O Kwiterovich
Lipid Research Atherosclerosis Division, Department of Pediatrics, Johns Hopkins University, 550 North Broadway, Baltimore, MD 21205, USA
J Lipid Res 44:1143-55. 2003..In conclusion, phytosterolemic heterozygotes respond well to a Step 1 diet, and their response to a plant sterol ester challenge appears similar to that observed in normals... - Safety and efficacy of treatment of children and adolescents with elevated low density lipoprotein levels with a step two diet or with lovastatinP O Kwiterovich
Lipid Research Clinic and Laboratory, Johns Hopkins University School of Medicine, 550 North Broadway, Suite 308, Baltimore, MD 21205, USA
Nutr Metab Cardiovasc Dis 11:30-4. 2001..The aim of this report was to examine available data on the safety and efficacy of treatment of children and adolescents with elevated LDL-cholesterol (LDL-C)... - Lipoprotein heterogeneity: diagnostic and therapeutic implicationsPeter O Kwiterovich
Lipid Research Atherosclerosis Division, Departments of Pediatrics and Medicine, The Johns Hopkins University School of Medicine, University Lipid Clinic, Baltimore, Maryland 21205, USA
Am J Cardiol 90:1i-10i. 2002 - Efficacy and safety of lovastatin therapy in adolescent girls with heterozygous familial hypercholesterolemiaSarah B Clauss
The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Pediatrics 116:682-8. 2005..The present study was designed to evaluate the lipid-altering efficacy, safety, and tolerability of lovastatin treatment in adolescent girls with heterozygous familial hypercholesterolemia... - miniSAGE: gene expression profiling using serial analysis of gene expression from 1 microg total RNAS Q Ye
Lipid Research Atherosclerosis Division, Department of Pediatrics, CMSC 604, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, Maryland 21287, USA
Anal Biochem 287:144-52. 2000..The preliminary analysis of 3838 tags from one library demonstrated a typical fibroblast gene expression pattern. This miniSAGE technique will permit a broader application of SAGE... - Effect of soy protein-containing isoflavones on lipoproteins in postmenopausal womenJerilyn K Allen
Johns Hopkins University School of Nursing, Baltimore, MD 21205, USA
Menopause 14:106-14. 2007.... - An HphI polymorphism in the E-selectin gene is associated with premature coronary artery diseaseF Zheng
Lipid Research Atherosclerosis Division, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Clin Genet 59:58-64. 2001..cigarette smoking and the S128R mutation) by multiple logistic analysis, the G98T mutation in the E-selectin gene was still a significant predictor of premature CAD [p = 0.022, odds ratio (95%, CI)= 3.58 (1.20-10.67)]... - Efficacy and safety of lowering dietary intake of total fat, saturated fat, and cholesterol in children with elevated LDL cholesterol: the Dietary Intervention Study in ChildrenR M Lauer
University of Iowa Hospitals and Clinics, Department of Pediatrics, Iowa City, IA 52242, USA
Am J Clin Nutr 72:1332S-1342S. 2000..Few studies have shown the efficacy and safety of lower-fat diets in children... - Long-term safety and efficacy of low-fat diets in children and adolescentsS B Clauss
Johns Hopkins Medical Institutions, Baltimore, MD, USA
Minerva Pediatr 54:305-13. 2002..In each of the 5 studies in which efficacy was determined, a significant decrease in the levels of total or LDL cholesterol was observed. Low-fat diets are generally safe and efficacious when performed under medical supervision... - Influence of genetic polymorphisms on responsiveness to dietary fat and cholesterolS Q Ye
Lipid Research Atherosclerosis Division, Departments of Pediatrics and Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Am J Clin Nutr 72:1275S-1284S. 2000.... - Apolipoprotein A1 Baltimore (Arg10----Leu), a new ApoA1 variantJ A Ladias
Department of Pediatrics, John Hopkins University, School of Medicine, Baltimore, MD 21205
Hum Genet 84:439-45. 1990..No effect of the mutant on any lipoprotein phenotype could be established... - Beyond low-density lipoprotein cholesterol: defining the role of low-density lipoprotein heterogeneity in coronary artery diseaseJames O Mudd
Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore Maryland, USA
J Am Coll Cardiol 50:1735-41. 2007.... - Higher self-reported physical activity is associated with lower systolic blood pressure: the Dietary Intervention Study in Childhood (DISC)Samuel S Gidding
Nemours Cardiac Center, A I duPont Children s Hospital and Thomas Jefferson University, Wilmington, Delaware 19899, USA
Pediatrics 118:2388-93. 2006.... - Diet and sex hormones in boys: findings from the dietary intervention study in childrenJoanne F Dorgan
Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
J Clin Endocrinol Metab 91:3992-6. 2006..Diet reportedly alters serum sex hormone concentrations in adults, but little is known about the influence of diet during puberty on these hormones... - Diet and sex hormones in girls: findings from a randomized controlled clinical trialJoanne F Dorgan
Fox Chase Cancer Center, Philadelphia, PA 19111, USA
J Natl Cancer Inst 95:132-41. 2003..We evaluated whether an intervention to lower fat intake among adolescent girls altered their serum concentrations of sex hormones that, in adults, are related to breast cancer development... - A summary of results of the Dietary Intervention Study in Children (DISC): lessons learnedLinda Van Horn
Department of Preventive Medicine, Northwestern University Medical School, 680 North Lake Shore Drive, 1102, Chicago, IL 60611, USA
Prog Cardiovasc Nurs 18:28-41. 2003..Highlights of key lessons learned from DISC and translational applications of potential interest to nurses and other health care providers are presented...