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| E H KossoffSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Discontinuing the ketogenic diet in seizure-free children: recurrence and risk factorsCelina C Martinez
School of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Epilepsia 48:187-90. 2007..The presence of recent EEG epileptiform activity, abnormal MRI, lower initial seizure frequency, and tuberous sclerosis complex all significantly increased the likelihood of recurrence...- Decreased relative efficacy of the ketogenic diet for children with surgically approachable epilepsyRebecca S Stainman
Department of Neurology and Pediatrics, The John M Freeman Pediatric Epilepsy Center, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Seizure 16:615-9. 2007..In children with intractable, surgically approachable epilepsy, the ketogenic diet is often perceived as less efficacious than surgery... 
Efficacy of dietary therapy for juvenile myoclonic epilepsyEric H Kossoff
Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA Electronic address
Epilepsy Behav 26:162-4. 2013..In this limited experience, the modified Atkins diet was an efficacious adjunctive therapy for young adults with very medically resistant JME...- How do parents find out about the ketogenic diet?Eric H Kossoff
Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Epilepsy Behav 24:445-8. 2012..A score of 10 was more likely seen in those who also scored their pediatrician with 10 (69% vs. 15%, p<0.001) and who were self-referred from our institution (56% vs. 27%, p=0.001)... - Dietary therapies: a worldwide phenomenonEric H Kossoff
The John M Freeman Pediatric Epilepsy Center, Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Epilepsy Res 100:205-9. 2012..Additionally, future clinical and research goals for each area were discussed. This article summarizes these talks and the use of the ketogenic diet worldwide... - Ketogenic diets: where do we go from here?Eric H Kossoff
The John M Freeman Pediatric Epilepsy Center, Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Epilepsy Res 100:344-6. 2012..Clinical researchers, basic scientists, dietitians, and parents discussed their goals and the results are presented in this article... - Ketogenic diets: new advances for metabolism-based therapiesEric H Kossoff
Departments of Neurology and Pediatrics, The John M Freeman Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Curr Opin Neurol 25:173-8. 2012..Many of these patients will now turn to dietary therapies such as the ketogenic diet, medium-chain triglyceride diet, modified Atkins diet, and low glycemic index treatment... - Intractable childhood epilepsy: choosing between the treatmentsEric H Kossoff
Johns Hopkins Hospital, Baltimore, MD 21287, USA
Semin Pediatr Neurol 18:145-9. 2011..In this review and special issue, a practical approach to management options for children who have refractory epilepsy will be presented from experts in the field... - Combined ketogenic diet and vagus nerve stimulation: rational polytherapy?Eric H Kossoff
The Johns Hopkins Hospital, Baltimore, Maryland 21287 1000, USA
Epilepsia 48:77-81. 2007..The concept of "rational polypharmacy" has been associated with anticonvulsant management for decades, but the term has not been applied to nonpharmacologic therapies... - Ketogenic diets: an update for child neurologistsEric H Kossoff
The John M Freeman Pediatric Epilepsy Center, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Child Neurol 24:979-88. 2009..Researchers are also highly interested in using diets for neurologic disorders other than epilepsy, including autism and brain tumors. This review will update child neurologists on the recent advances in the use of ketogenic diets... - A case-control evaluation of the ketogenic diet versus ACTH for new-onset infantile spasmsEric H Kossoff
Department of Neurology, John M Freeman Pediatric Epilepsy Center, Johns Hopkins Medical Institutes, Baltimore, Maryland 21287 1000, USA
Epilepsia 49:1504-9. 2008..We hypothesized the ketogenic diet (KD), previously reported as beneficial for intractable infantile spasms, would have similar efficacy, but better tolerability than ACTH when used first-line... - Treatment of infantile spasmsPhilip J Overby
Department of Pediatric Neurology, Johns Hopkins Hospital, 600 North Wolfe Street, Jefferson 123, Baltimore, MD 21287, USA
Curr Treat Options Neurol 8:457-64. 2006..There is urgent need for further treatment trials comparing anticonvulsants with ACTH and a satisfactory animal model for the study of spasms... - When do seizures usually improve with the ketogenic diet?Eric H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Epilepsia 49:329-33. 2008..The purpose of this study was to determine the typical time to seizure reduction as well as the time after which it was unlikely to be helpful in those children started on the KD... - Infantile spasmsEric H Kossoff
Department of Neurology, The John M Freeman Pediatric Epilepsy Center, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
Neurologist 16:69-75. 2010..Despite its existence in the literature since 1841, proven therapies are limited because of efficacy, tolerability, at times even availability... - Medication-overuse headache in children: is initial preventive therapy necessary?Eric H Kossoff
Department of Neurology, The John Hopkins Medical Institutions, Baltimore, MD 21287, USA
J Child Neurol 21:45-8. 2006..Should headaches persist after 1 month, such agents can be added. (J Child Neurol 2006;21:45-48)... - High-dose oral prednisolone for infantile spasms: an effective and less expensive alternative to ACTHEric H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Epilepsy Behav 14:674-6. 2009..16. Oral prednisolone had fewer adverse effects (53% vs 80%, P=0.10) and was less expensive ($200 vs approximately $70,000) than ACTH. We now routinely recommend oral prednisolone to all families of children with infantile spasms... - An infantile-onset, severe, yet sporadic seizure pattern is common in Sturge-Weber syndromeEric H Kossoff
The Johns Hopkins Hospital, Baltimore, MD 21287 1000, USA
Epilepsia 50:2154-7. 2009..This seizure pattern appears to be common with SWS and leads to difficult treatment decisions, especially in regard to the timing of potential surgical resection... - A pilot study transitioning children onto levetiracetam monotherapy to improve language dysfunction associated with benign rolandic epilepsyEric H Kossoff
The Johns Hopkins Hospital, Baltimore, MD, USA
Epilepsy Behav 11:514-7. 2007..08). Seizures improved in five, decreasing from 2.7 to 1.0 seizure per 6 months (P=0.11). Results from this pilot study suggest that levetiracetam may have a beneficial effect on language in children with BRE... - A prospective study of the modified Atkins diet for intractable epilepsy in adultsEric H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Epilepsia 49:316-9. 2008..The modified Atkins diet has been recently demonstrated to be therapeutic for children without the need for an admission, fasting period, weighing of foods, or fluid, calorie, and protein restriction... - Self-reported treatment patterns in patients with Sturge-Weber syndrome and migrainesEric H Kossoff
Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
J Child Neurol 22:720-6. 2007..The small sample size precludes any safety analysis, however, and future prospective trials of both treatment options are needed... - The modified Atkins diet: a potential treatment for developing countriesEric H Kossoff
The Johns Hopkins Medical Institutions, Baltimore, Maryland, U.S.A
Epilepsia 49:1646-7. 2008 - Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study GroupEric H Kossoff
The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Epilepsia 50:304-17. 2009..This paper highlights recommendations based on best evidence, including areas of agreement and controversy, unanswered questions, and future research... - Home-guided use of the ketogenic diet in a patient for more than 20 yearsEric H Kossoff
John M Freeman Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Pediatr Neurol 36:424-5. 2007..He remains on the diet to date, now for 21 years of continuous duration... - International consensus statement on clinical implementation of the ketogenic diet: agreement, flexibility, and controversyEric H Kossoff
The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Epilepsia 49:11-3. 2008..This group effort highlights recommendations based on best evidence, including areas of agreement and controversy, unanswered questions, and future research... - The modified Atkins dietEric H Kossoff
The Johns Hopkins Hospital, Baltimore, MD 21287, USA
Epilepsia 49:37-41. 2008..Lastly, the possible future benefits of this treatment for new-onset seizures, adults, neurologic conditions other than epilepsy, and developing countries of the world will be discussed... - A randomized, crossover comparison of daily carbohydrate limits using the modified Atkins dietEric H Kossoff
The Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Epilepsy Behav 10:432-6. 2007..A starting carbohydrate limit of 10 g per day for children starting the modified Atkins diet may be ideal, with a planned increase to a more tolerable 20 g per day after 3 months... - A modified Atkins diet is effective for the treatment of intractable pediatric epilepsyEric H Kossoff
John M Freeman Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, The Johns Hopkins Medical Institutions, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MS 21287 1000, U S A
Epilepsia 47:421-4. 2006..Our objective was to evaluate the efficacy and tolerability of a modified Atkins diet for intractable childhood epilepsy... - Prospective study of the modified atkins diet in combination with a ketogenic liquid supplement during the initial monthEric H Kossoff
The John M Freeman Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
J Child Neurol 26:147-51. 2011..8:1 versus 1.0:1 in the modified Atkins diet alone, P = .0002), but did not change urinary or serum ketosis. The addition of a ketogenic supplement to the modified Atkins diet during its initial month appears to be beneficial... - Hemispherectomy for intractable unihemispheric epilepsy etiology vs outcomeE H Kossoff
Department of Neurology, The Pediatric Epilepsy Center, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Neurology 61:887-90. 2003..A prior case series focused on the outcomes after 58 surgeries at Johns Hopkins Hospital in 1997. This series, and an additional 53 cases, were reviewed to bring the outcomes up to date... - Landau-Kleffner syndrome responsive to levetiracetamEric H Kossoff
Department of Neurology, The Johns Hopkins Hospital, Jefferson 128, 600 North Wolfe Street, Baltimore, MD 21287 1000, USA
Epilepsy Behav 4:571-5. 2003..Levetiracetam should be considered as therapy for Landau-Kleffner syndrome... - Migraine and epilepsyEric H Kossoff
Johns Hopkins Hospital, Baltimore, MD, USA
Semin Pediatr Neurol 17:117-22. 2010..Although the abortive agents used are vastly different, the preventative treatments share mostly similarities, and are commonly anticonvulsant drugs... - Outcomes of 32 hemispherectomies for Sturge-Weber syndrome worldwideEric H Kossoff
Pediatric Epilepsy Center, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Neurology 59:1735-8. 2002..Epilepsy affects 80% of patients with Sturge-Weber syndrome; the majority of seizures begin before the age of 1. When seizures are intractable to medications and unihemispheric, hemispherectomy is often advised... - The postoperative course and management of 106 hemidecorticationsE H Kossoff
Department of Neurology and Pediatrics, The Pediatric Epilepsy Center, Johns Hopkins Medicla Institutions, Baltimore, MD, USA
Pediatr Neurosurg 37:298-303. 2002..The purpose of this study was to evaluate the short-term issues surrounding hemispherectomy and their management in a series of patients from our institution... - Kidney stones, carbonic anhydrase inhibitors, and the ketogenic dietEric H Kossoff
The Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, and Division of Pediatric Nephrology, Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 1000, USA
Epilepsia 43:1168-71. 2002..The objective of this study was to establish the prevalence of nephrolithiasis in children in this combination-therapy population... - Neonatal hypocalcemic seizures: case report and literature reviewEric H Kossoff
Pediatric Epilepsy, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Child Neurol 17:236-9. 2002..This case highlights the clinical course of neonatal hypocalcemic seizures, EEG findings in several cases, and possible mechanisms for both hypocalcemic precipitation of seizures and anticonvulsant ineffectiveness... - Efficacy of the ketogenic diet for infantile spasmsEric H Kossoff
Department of Neurology, Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Pediatrics 109:780-3. 2002..The objective of this study was to determine whether the ketogenic diet is safe, well-tolerated, and efficacious in the treatment of infantile spasms... - Ketogenic diets: evidence for short- and long-term efficacyEric H Kossoff
John M Freeman Pediatric Epilepsy Center, Department of Neurology, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurotherapeutics 6:406-14. 2009..This potential antiepileptogenic activity has been recently demonstrated in some animal studies as well. This review discusses the animal and human evidence for both short- and long-term benefits of dietary therapies... - Efficacy of the Atkins diet as therapy for intractable epilepsyEric H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287 1000, USA
Neurology 61:1789-91. 2003..This provides preliminary evidence that the Atkins diet may have a role as therapy for patients with medically resistant epilepsy... - Improvement in alertness and behavior in children treated with combination topiramate and vagus nerve stimulationEric H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Epilepsy Behav 5:256-9. 2004..This did not appear to be due solely to seizure reduction, which was observed only differentially at 12 months... - Comorbidity of epilepsy and headache in patients with Sturge-Weber syndromeEric H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
J Child Neurol 20:678-82. 2005..Correlations of family history with both age at symptom onset and behavior problems suggest that genetic substrate could be one factor determining the variable neurologic manifestations seen in Sturge-Weber syndrome... - Tuberous sclerosis complex and the ketogenic dietEric H Kossoff
Departments of Neurology and Pediatrics, The John M Freeman Pediatric Epilepsy Center, Johns Hopkins University, Baltimore, MD 212871000, USA
Epilepsia 46:1684-6. 2005..If medications fail and no clear epileptogenic tuber is identified, nonpharmacologic therapies are often attempted. The use of the ketogenic diet specifically for children with TSC and epilepsy has not been previously described... - A pilot study of the modified Atkins diet for Sturge-Weber syndromeEric H Kossoff
The John M Freeman Pediatric Epilepsy Center, Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Epilepsy Res 92:240-3. 2010..Five children aged 4-18 years with SWS and at least monthly intractable seizures were started prospectively on the MAD for 6 months. All children had urinary ketosis and seizure improvement, including 3 with > 50% seizure reduction... - Will seizure control improve by switching from the modified Atkins diet to the traditional ketogenic diet?Eric H Kossoff
Neurology, The Johns Hopkins University, Baltimore, Maryland, USA
Epilepsia 51:2496-9. 2010..004), including all who became seizure-free. These results suggest that the KD probably represents a "higher dose" of dietary therapy than the MAD, which may particularly benefit those with myoclonic-astatic epilepsy... - Effect of an external responsive neurostimulator on seizures and electrographic discharges during subdural electrode monitoringEric H Kossoff
Department of Pediatrics and Neurology, Johns Hopkins Hospital, Baltimore, Maryland 21287 1000, USA
Epilepsia 45:1560-7. 2004..Approved neural-stimulation therapies for epilepsy use prolonged intermittent stimulation paradigms with no ability to respond automatically to seizures... - The impact of early versus late anticonvulsant reduction after ketogenic diet initiationEric H Kossoff
Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Epilepsy Behav 5:499-502. 2004..Early reduction of anticonvulsants in children initiated on the ketogenic diet appears to be safe and well tolerated. However, it offers no specific advantage compared with a later taper... - More fat and fewer seizures: dietary therapies for epilepsyEric H Kossoff
The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 1000, USA
Lancet Neurol 3:415-20. 2004..Dietary therapies may become even more valuable in the therapy of epilepsy when the mechanisms underlying their success are understood... - Worldwide use of the ketogenic dietEric H Kossoff
The Pediatric Epilepsy Center, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 1000, USA
Epilepsia 46:280-9. 2005..Over the past decade, the use of the ketogenic diet internationally has increased dramatically. The purpose of this survey was to evaluate the use of the diet worldwide... - The outcome of children with intractable seizures: a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one yearElisabeth B Marsh
John M. Freeman Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, The Johns Hopkins Medical Institutions, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MS 21287-1000, U.S.A
Epilepsia 47:425-30. 2006..Whether or not the diet was effective, most families did not regret trying it and would recommend it to others... - Lack of influence of body mass index on the efficacy of the ketogenic dietRana F Hamdy
Johns Hopkins University School of Medicine, Hopkins Medical Institutions, Baltimore, MD 21287, USA
J Child Neurol 22:1167-71. 2007..Attributing changes in seizure control to a rapid weight gain or loss may be unjustified... - The ketogenic diet: adolescents can do it, tooMackenzie A Mady
Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Epilepsia 44:847-51. 2003..CONCLUSIONS: The ketogenic diet is as well tolerated and efficacious for adolescents with epilepsy as for the general childhood population... - Can you predict an immediate, complete, and sustained response to the ketogenic diet?Khoi D Than
The Johns Hopkins University School of Medicine, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Epilepsia 46:580-2. 2005..Although the ketogenic diet has been in use for >80 years, little agreement exists as to which patients are most likely to have dramatic, sudden, and complete seizure control... - Management and risk factors for dyslipidemia with the ketogenic dietJunaid Nizamuddin
Johns Hopkins University School of Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
J Child Neurol 23:758-61. 2008..11). Hypercholesterolemia occurs in most children receiving a solid food based ketogenic diet but improved in approximately half, even without interventions... - Levetiracetam psychosis in children with epilepsyE H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 7247, USA
Epilepsia 42:1611-3. 2001..Observations in children are limited; levetiracetam is not yet approved by the Food and Drug Administration for use in children... - Empiric use of potassium citrate reduces kidney-stone incidence with the ketogenic dietMelanie A McNally
School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Pediatrics 124:e300-4. 2009..Potassium citrate (Polycitra K) is a daily oral supplement that alkalinizes the urine and solubilizes urine calcium, theoretically reducing the risk for kidney stones... - Kidney stones and the ketogenic diet: risk factors and preventionAmitha Sampath
School of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Child Neurol 22:375-8. 2007..As oral potassium citrate was preventative, prospective studies using this medication empirically are warranted... - The ketogenic dietSaurabh R Sinha
Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurologist 11:161-70. 2005..Investigations of the diet are providing new insight into the mechanisms behind seizures and epilepsy itself, as well as possible new therapies... - The importance of parental expectations of cognitive improvement for their children with epilepsy prior to starting the ketogenic dietSharifeh Farasat
Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Epilepsy Behav 8:406-10. 2006..001) and >90% seizure reduction (P=0.04) at 6 months positively correlated with longer eventual diet duration. Expectations for cognitive improvement need to be discussed prior to beginning the ketogenic diet... 
Ischemic stroke in children with critical illness: a poor prognostic signLori C Jordan
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Pediatr Neurol 36:244-6. 2007..Mortality resulted primarily from the underlying illness. Prognosis after stroke is markedly worsened in children with premorbid critical illness...- Experience in the use of the ketogenic diet as early therapyJames E Rubenstein
Department of Neurology, Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, MD 21287 1000, USA
J Child Neurol 20:31-4. 2005..6). The ketogenic diet can be a valuable therapy before epilepsy becomes intractable. In the 13 patients reported, efficacy without side effects was achieved similarly to that with patients with intractable epilepsy... - Encephalofacial angiomatosis sparing the occipital lobe and without facial nevus: on the spectrum of Sturge-Weber syndrome variants?Anne M Comi
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Child Neurol 18:35-8. 2003..This diagnosis should be considered in any child presenting with seizures or complicated migraines and intracranial calcifications... - Quantitative EEG asymmetry correlates with clinical severity in unilateral Sturge-Weber syndromeLaura A Hatfield
Department of Neurology, Kennedy Krieger Institute, Baltimore, MD 21205, USA
Epilepsia 48:191-5. 2007..SWS results in ischemic brain injury, seizures, and neurologic deficits. We hypothesized that a decrease in quantitative EEG (qEEG) power, on the affected side, correlates with clinical severity in subjects with SWS... - Myoclonic-astatic epilepsy in a child with Sturge-Weber syndromeJoshua B Ewen
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Pediatr Neurol 36:115-7. 2007..In such cases, treatment with a broad-spectrum antiepileptic may be advantageous... - Children with seizures exhibit preferences for foods compatible with the ketogenic dietAdrianna Amari
Department of Behavioral Psychology, The Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA
Epilepsy Behav 11:98-104. 2007..Research into the underlying metabolic basis for this preference and possible related neurophysiological mechanisms in seizure etiology and treatment is warranted... - A blinded, crossover study of the efficacy of the ketogenic dietJohn M Freeman
Departments of Neurology and Pediatrics, The John M Freeman Pediatric Epilepsy Center, Baltimore, Maryland, USA
Epilepsia 50:322-5. 2009..5 seizures per day (p = 0.07). There was no reduction in the number of EEG-identified events, with a median reduction of 7 events per day (p = 0.33). Ketosis was not completely eliminated in the glucose-added arm... - Aicardi syndrome mimicking intrauterine hydrocephalusDeivasumathy Muthugovindan
Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Brain Dev 31:638-40. 2009..Aicardi syndrome most commonly comes to medical attention because of seizures later in infancy... - Secondary intracranial causes for headaches in childrenRooman Ahad
Department of Neurology, Division of Pediatric Neurology, Johns Hopkins Hospital, 200 N Wolfe Street, Baltimore, MD 21287, USA
Curr Pain Headache Rep 12:373-8. 2008..This article discusses these secondary causes of headaches due to primary brain etiologies, focusing on aspects of the history that should lead a neurologist to order neuroimaging or electroencephalographic studies for these children... - Cortical auditory dysfunction in benign rolandic epilepsyDana F Boatman
Department of Neurology, John Hopkins Hospital, Baltimore 21287, USA
Epilepsia 49:1018-26. 2008..To evaluate cortical auditory function, including speech recognition, in children with benign rolandic epilepsy (BRE)... - The ketogenic diet: one decade laterJohn M Freeman
John M Freeman Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, MD 21287 7247, USA
Pediatrics 119:535-43. 2007..Finally, this review looks toward possible future uses of the ketogenic diet for conditions other than epilepsy... - Hemiparesis is a clinical correlate of general adaptive dysfunction in children and adolescents with Sturge-Weber syndromeJennifer Reesman
Kennedy Krieger Institute, Baltimore, Maryland 21231, USA
J Child Neurol 24:701-8. 2009..Information obtained during neurological examination of children and adolescents with Sturge-Weber syndrome particularly hemiparetic status is useful for identifying children who may need additional intervention... - Long-term use of the ketogenic diet in the treatment of epilepsyDarcy K Groesbeck
The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Dev Med Child Neurol 48:978-81. 2006..Efficacy and overall tolerability for children are maintained after prolonged use of the ketogenic diet. However, side effects, such as slowed growth, kidney stones, and fractures, should be monitored closely... - Recurrent hypoglycemic hemiparesis and aphasia in an adolescent patientE H Kossoff
Department of Pediatric Neurology, Johns Hopkins Hospital-Pathology 509, 600 North Wolfe Street, Baltimore, MD 21287, USA
Pediatr Neurol 24:385-6. 2001..Ten months later, she had a recurrence of the same symptoms, which also resolved rapidly. This potential complication of hypoglycemia is often mistaken for a cerebrovascular accident... - The influence of concurrent anticonvulsants on the efficacy of the ketogenic dietPeter F Morrison
The Johns Hopkins Hospital, Baltimore, MD 21287 1000, USA
Epilepsia 50:1999-2001. 2009..04). These results provide practical information to clinicians who are treating children receiving both the KD and anticonvulsants... - Hemispherectomy-associated complications from the Kids' Inpatient DatabaseMohamad Z Koubeissi
Department of Neurology, University Hospitals Case Medical Center, Case School of Medicine, Cleveland, OH, USA
Epilepsy Res 87:47-53. 2009..6% across studies, mostly due to acute hemorrhage. The purpose of this study was to evaluate in-hospital mortality and predictors of the need for blood transfusion during HS in a large, nationwide cohort in recent years... - Benefits of an all-liquid ketogenic dietEric H Kossoff
Epilepsia 45:1163. 2004 - The intracerebral administration of phenytoin using controlled-release polymers reduces experimental seizures in ratsRafael J Tamargo
Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Epilepsy Res 48:145-55. 2002..In rats, the long-term interstitial delivery of phenytoin in the brain was not associated with any deleterious effects... - State of the ketogenic diet(s) in epilepsyJennifer Huffman
Curr Neurol Neurosci Rep 6:332-40. 2006..This review addresses these studies, as well as recent research regarding possible indications for the diet, variations in its initiation, side effect profiles, and the recent use of modified formulations to improve tolerability... - Epilepsy surgery for the neurocutaneous disordersAdam L Hartman
Johns Hopkins Medical Institutions, Baltimore, MD 21287-1000, USA
Semin Pediatr Neurol 13:63-7. 2006..Options for surgical resection range from focal resections (in those with localized disease) to hemispherectomies (in those with hemispheric involvement)...