Ming Teng Koh

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Selective GABA(A) α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment
    Ming Teng Koh
    Department of Psychological and Brain Sciences, Johns Hopkins University, Ames Hall, 3400 North Charles Street, Baltimore, MD 21218, USA
    Neuropharmacology 64:145-52. 2013
  2. ncbi [Pharmacological treatment strategies targeting cognitive impairment associated with aging]
    Ming Teng Koh
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Nihon Yakurigaku Zasshi 139:157-9. 2012
  3. pmc Hippocampal lesions interfere with long-trace taste aversion conditioning
    Ming Teng Koh
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, United States
    Physiol Behav 98:103-7. 2009
  4. pmc Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment
    Ming Teng Koh
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA
    Neuropsychopharmacology 35:1016-25. 2010
  5. doi Hilar interneuron vulnerability distinguishes aged rats with memory impairment
    Amy M Spiegel
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland, 21218
    J Comp Neurol 521:3508-23. 2013
  6. pmc Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats
    Sunggu Yang
    The Mind Brain Institute, Johns Hopkins University, Baltimore, Maryland 21218, USA
    J Neurosci 33:12670-8. 2013
  7. pmc Rapid encoding of new information alters the profile of plasticity-related mRNA transcripts in the hippocampal CA3 region
    Rebecca P Haberman
    Department of Psychological and Brain Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21218, USA
    Proc Natl Acad Sci U S A 105:10601-6. 2008
  8. pmc Behaviorally activated mRNA expression profiles produce signatures of learning and enhanced inhibition in aged rats with preserved memory
    Rebecca P Haberman
    Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 8:e83674. 2013
  9. pmc Mindspan: lessons from rat models of neurocognitive aging
    Michela Gallagher
    Department of Psychological and Brain Sciences, Johns Hopkins University, Ames Hall, 3400 North Charles Street, Baltimore, MD 21218, USA
    ILAR J 52:32-40. 2011
  10. pmc Episodic memory on the path to Alzheimer's disease
    Michela Gallagher
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA
    Curr Opin Neurobiol 21:929-34. 2011

Collaborators

Detail Information

Publications10

  1. pmc Selective GABA(A) α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment
    Ming Teng Koh
    Department of Psychological and Brain Sciences, Johns Hopkins University, Ames Hall, 3400 North Charles Street, Baltimore, MD 21218, USA
    Neuropharmacology 64:145-52. 2013
    ..These data suggest a novel approach to improve neural network function in clinical conditions of excess hippocampal activity. This article is part of a Special Issue entitled 'Cognitive Enhancers'...
  2. ncbi [Pharmacological treatment strategies targeting cognitive impairment associated with aging]
    Ming Teng Koh
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Nihon Yakurigaku Zasshi 139:157-9. 2012
    ..Such therapy, in addition to memory improvement, may also have disease modifying potential because hippocampal overactivity in aging/MCI predicts further cognitive decline and conversion to Alzheimer's disease...
  3. pmc Hippocampal lesions interfere with long-trace taste aversion conditioning
    Ming Teng Koh
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, United States
    Physiol Behav 98:103-7. 2009
    ..The results replicate past dissociations of dorsal and ventral hippocampal function, and also suggest that the hippocampus has a less differentiated role in long-trace taste aversion learning...
  4. pmc Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment
    Ming Teng Koh
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA
    Neuropsychopharmacology 35:1016-25. 2010
    ....
  5. doi Hilar interneuron vulnerability distinguishes aged rats with memory impairment
    Amy M Spiegel
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland, 21218
    J Comp Neurol 521:3508-23. 2013
    ..Together these findings confirm the vulnerability of hippocampal interneurons to normal aging and highlight that the integrity of a specific subpopulation in the hilus is coupled with age-related memory impairment...
  6. pmc Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats
    Sunggu Yang
    The Mind Brain Institute, Johns Hopkins University, Baltimore, Maryland 21218, USA
    J Neurosci 33:12670-8. 2013
    ..Age-unimpaired rats, in contrast, had intact mGluR LTD. These findings indicate that the integrity of mGluR-LTD at A/C → CA3 inputs may play a crucial role in maintaining the performance of CA3 circuitry in aging...
  7. pmc Rapid encoding of new information alters the profile of plasticity-related mRNA transcripts in the hippocampal CA3 region
    Rebecca P Haberman
    Department of Psychological and Brain Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21218, USA
    Proc Natl Acad Sci U S A 105:10601-6. 2008
    ..Furthermore, siRNA inhibition of nlgn1 within the CA3 subregion impaired spatial memory performance, pointing to mechanisms of synaptic remodeling as a basis for rapid encoding of new information in long-term memory...
  8. pmc Behaviorally activated mRNA expression profiles produce signatures of learning and enhanced inhibition in aged rats with preserved memory
    Rebecca P Haberman
    Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 8:e83674. 2013
    ..These data support the conclusion that aged subjects with preserved memory recruit adaptive mechanisms to retain tight control over excitability under both basal and activated conditions. ..
  9. pmc Mindspan: lessons from rat models of neurocognitive aging
    Michela Gallagher
    Department of Psychological and Brain Sciences, Johns Hopkins University, Ames Hall, 3400 North Charles Street, Baltimore, MD 21218, USA
    ILAR J 52:32-40. 2011
    ....
  10. pmc Episodic memory on the path to Alzheimer's disease
    Michela Gallagher
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA
    Curr Opin Neurobiol 21:929-34. 2011
    ....