Karen E King

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. doi request reprint Streamlining ABO antibody titrations for monitoring ABO-incompatible kidney transplants
    R Sue Shirey
    Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland 21287 6667, USA
    Transfusion 50:631-4. 2010
  2. ncbi request reprint Universal leukoreduction decreases the incidence of febrile nonhemolytic transfusion reactions to RBCs
    Karen E King
    Department of Pathology, Johns Hopkins Hospital, Baltimore, MD 21287 6667, USA
    Transfusion 44:25-9. 2004
  3. doi request reprint The critical role of plasmapheresis in ABO-incompatible renal transplantation
    Aaron A R Tobian
    Department of Pathology, Transfusion Medicine Division, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Transfusion 48:2453-60. 2008
  4. doi request reprint Desensitization in HLA-incompatible kidney recipients and survival
    Robert A Montgomery
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    N Engl J Med 365:318-26. 2011
  5. pmc ABO antibody titers are not predictive of hemolytic reactions due to plasma-incompatible platelet transfusions
    Matthew S Karafin
    Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA
    Transfusion 52:2087-93. 2012
  6. pmc C4d deposition without rejection correlates with reduced early scarring in ABO-incompatible renal allografts
    Mark Haas
    Department of Pathology, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Pathology 712, Baltimore, MD 21287, USA
    J Am Soc Nephrol 20:197-204. 2009
  7. pmc Allergic transfusion reactions to platelets are associated more with recipient and donor factors than with product attributes
    William J Savage
    Department of Pathology, Division of Transfusion Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Transfusion 51:1716-22. 2011
  8. doi request reprint Prevention of allergic transfusion reactions to platelets and red blood cells through plasma reduction
    Aaron A R Tobian
    Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA
    Transfusion 51:1676-83. 2011
  9. ncbi request reprint Plasmapheresis, CMV hyperimmune globulin, and anti-CD20 allow ABO-incompatible renal transplantation without splenectomy
    Christopher J Sonnenday
    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Transplant 4:1315-22. 2004
  10. pmc The impact of apheresis platelet manipulation on corrected count increment
    Matthew Karafin
    Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Transfusion 52:1221-7. 2012

Collaborators

Detail Information

Publications30

  1. doi request reprint Streamlining ABO antibody titrations for monitoring ABO-incompatible kidney transplants
    R Sue Shirey
    Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland 21287 6667, USA
    Transfusion 50:631-4. 2010
    ..Therefore, we assessed AHG titers by two methods: 1) a revised test tube (TT) method without RT and 2) an anti-immunoglobulin G (IgG) gel microcolumn (IgG gel) method with a goal of streamlining ABO antibody titrations...
  2. ncbi request reprint Universal leukoreduction decreases the incidence of febrile nonhemolytic transfusion reactions to RBCs
    Karen E King
    Department of Pathology, Johns Hopkins Hospital, Baltimore, MD 21287 6667, USA
    Transfusion 44:25-9. 2004
    ..A retrospective analysis is reported here of FNHTRs in RBC recipients as the inventory increased in percentage of leukoreduced RBC units...
  3. doi request reprint The critical role of plasmapheresis in ABO-incompatible renal transplantation
    Aaron A R Tobian
    Department of Pathology, Transfusion Medicine Division, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Transfusion 48:2453-60. 2008
    ..This article reviews the literature to provide a historical perspective of TPE for ABO-I kidney transplantation and also provides the Johns Hopkins Hospital protocol with a focus on both titers and TPE...
  4. doi request reprint Desensitization in HLA-incompatible kidney recipients and survival
    Robert A Montgomery
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    N Engl J Med 365:318-26. 2011
    ..Whether such antibody depletion results in a survival benefit as compared with waiting for an HLA-compatible kidney is unknown...
  5. pmc ABO antibody titers are not predictive of hemolytic reactions due to plasma-incompatible platelet transfusions
    Matthew S Karafin
    Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA
    Transfusion 52:2087-93. 2012
    ....
  6. pmc C4d deposition without rejection correlates with reduced early scarring in ABO-incompatible renal allografts
    Mark Haas
    Department of Pathology, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Pathology 712, Baltimore, MD 21287, USA
    J Am Soc Nephrol 20:197-204. 2009
    ....
  7. pmc Allergic transfusion reactions to platelets are associated more with recipient and donor factors than with product attributes
    William J Savage
    Department of Pathology, Division of Transfusion Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Transfusion 51:1716-22. 2011
    ..Mechanisms of allergic transfusion reactions (ATRs) are not well understood. The aim of this study was to distinguish recipient-, donor-, and product-specific factors associated with ATRs...
  8. doi request reprint Prevention of allergic transfusion reactions to platelets and red blood cells through plasma reduction
    Aaron A R Tobian
    Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA
    Transfusion 51:1676-83. 2011
    ..This study evaluated whether removing plasma from apheresis platelets (APs) or red blood cells (RBCs) by concentrating or washing transfusion products can decrease the incidence of ATRs...
  9. ncbi request reprint Plasmapheresis, CMV hyperimmune globulin, and anti-CD20 allow ABO-incompatible renal transplantation without splenectomy
    Christopher J Sonnenday
    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Transplant 4:1315-22. 2004
    ..The use of rituximab, allowing avoidance of splenectomy, may further remove one of the significant disincentives to ABOi transplantation, and eliminate the risk of post-splenectomy infections...
  10. pmc The impact of apheresis platelet manipulation on corrected count increment
    Matthew Karafin
    Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Transfusion 52:1221-7. 2012
    ..However, these processes may damage platelets (PLTs). This study evaluated whether concentrating or washing APs decrease the corrected count increment (CCI)...
  11. ncbi request reprint ABO incompatible high-titer renal transplantation without splenectomy or anti-CD20 treatment
    Dorry L Segev
    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Transplant 5:2570-5. 2005
    ....
  12. ncbi request reprint Transfusion premedications: a growing practice not based on evidence
    Aaron A R Tobian
    Department of Pathology, Transfusion Medicine Division, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Transfusion 47:1089-96. 2007
  13. pmc Cost-effectiveness of prospective red blood cell antigen matching to prevent alloimmunization among sickle cell patients
    Seema Kacker
    Department of Pathology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland Department of Pathology, Brigham and Women s Hospital, Boston, Massachusetts
    Transfusion 54:86-97. 2014
    ..Prospective antigen matching can prevent alloimmunization, but is costly and may not benefit most patients...
  14. pmc Partially mismatched transplantation and human leukocyte antigen donor-specific antibodies
    Douglas E Gladstone
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Medicine, Baltimore, MD 21287, USA
    Biol Blood Marrow Transplant 19:647-52. 2013
    ....
  15. doi request reprint Therapeutic plasma exchange reduces ABO titers to permit ABO-incompatible renal transplantation
    Aaron A R Tobian
    Transfusion Medicine Division, Department of Pathology, Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Transfusion 49:1248-54. 2009
    ..Therapeutic plasma exchange (TPE) is performed to permit ABO-incompatible (ABO-I) kidney transplants, but little is known about how well TPE reduces ABO antibodies or complications related to TPE in this clinical setting...
  16. doi request reprint A comprehensive program to minimize platelet outdating
    Alice K Fuller
    Department of Pathology, HATS Division, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    Transfusion 51:1469-76. 2011
    ..It is imperative to have a sufficient number of products for patients requiring transfusion, but outdating PLTs is a financial burden and a waste of a resource...
  17. pmc Bacterial culture reduces but does not eliminate the risk of septic transfusion reactions to single-donor platelets
    Alice K Fuller
    Department of Pathology, Hemapheresis and Transfusion Services Division, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Transfusion 49:2588-93. 2009
    ..6 per 100,000; 95% confidence interval [CI], 0.17-36.9 per 100,000) transfusions. The goal of this study was to determine if bacterial testing of SDPs reduced the rate of SPTRs in our hospital...
  18. doi request reprint ABO incompatible renal transplantation: a paradigm ready for broad implementation
    Robert A Montgomery
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Transplantation 87:1246-55. 2009
    ....
  19. doi request reprint Thrombotic thrombocytopenic purpura at the Johns Hopkins Hospital from 1992 to 2008: clinical outcomes and risk factors for relapse
    Huichun Zhan
    Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Ross Research 1032, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Transfusion 50:868-74. 2010
    ..We aimed to describe the clinical spectrum of TTP, to determine the valid endpoint for plasma exchange cessation, and to explore the risk factors for disease relapse...
  20. doi request reprint Reduction in potassium concentration of stored red blood cell units using a resin filter
    Chisa Yamada
    Transfusion Medicine Division, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Transfusion 50:1926-33. 2010
    ..A potassium adsorption filter (PAF) was developed in Japan to remove K by exchanging with sodium (Na). We performed an in vitro evaluation of its efficacy and feasibility of use...
  21. doi request reprint A case study of a child with chronic hemolytic anemia due to a Donath-Landsteiner positive, IgM anti-I autoantibody
    Matthew S Karafin
    Division of Transfusion Medicine, Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    Pediatr Blood Cancer 59:953-5. 2012
    ..The clinical course is described and a discussion of PCH and the D-L antibody is presented. We also discuss intravenous immunoglobulin infusions as a therapy for children with this form of severe chronic autoimmune hemolytic anemia...
  22. ncbi request reprint Prevalence of HLA antibodies in transfused patients with and without red cell antibodies
    Orin Buetens
    Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland 21287 6667, USA
    Transfusion 46:754-6. 2006
    ..It is hypothesized that patients with RBC alloantibodies may be more likely to have HLA antibodies than previously transfused patients without RBC antibodies...
  23. ncbi request reprint Antibody, complement and accommodation in ABO-incompatible transplants
    Karen E King
    Department of Pathology, Johns Hopkins Medical Institutes, 720 Rutland Avenue, Baltimore, Maryland 21205 2196, USA
    Curr Opin Immunol 16:545-9. 2004
    ....
  24. doi request reprint Transfusion medicine in American undergraduate medical education
    Julie K Karp
    Department of Pathology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    Transfusion 51:2470-9. 2011
    ..To our knowledge, no comprehensive study has assessed how transfusion medicine is incorporated into undergraduate medical education...
  25. doi request reprint Autologous serum eyedrops: literature review and implications for transfusion medicine specialists
    Chisa Yamada
    Transfusion Medicine Division, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Transfusion 48:1245-55. 2008
    ..Given that ophthalmologists may consult the blood bank to request ASEs, transfusion medicine physicians should be aware of the issues related to ASE preparation, storage, and potential utility...
  26. ncbi request reprint Hypersplenism induced by splenic vein ligation
    Brian Garibaldi
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Am J Hematol 83:242-4. 2008
    ..We present the case of a patient with a previously undiagnosed warm AIHA, who developed worsening hemolysis after undergoing splenic vein ligation during a pancreaticoduodenectomy to remove a neuroendocrine tumor...
  27. doi request reprint International variation in volunteer whole blood donor eligibility criteria
    Julie K Karp
    Department of Pathology, Hemapheresis and Transfusion Support, The Johns Hopkins Hospital, Baltimore, Maryland 21205, USA
    Transfusion 50:507-13. 2010
    ..This study assesses international variation in volunteer whole blood donor eligibility criteria...
  28. ncbi request reprint Treatment of autoimmune hemolytic anemia
    Karen E King
    Transfusion Medicine Devision, Johns Hopkins Medical Institutions, Baltimore, MD 21287 6667, USA
    Semin Hematol 42:131-6. 2005
    ..Hemoglobin-based oxygen carriers may provide an important bridging therapy in the future. Requests for "least incompatible" blood do not enhance transfusion safety and often result in unnecessary delays...
  29. ncbi request reprint Apheresis platelet transfusions: does ABO matter?
    Jay H Herman
    Transfusion 44:802-4. 2004
  30. ncbi request reprint Successful renal transplantation across simultaneous ABO incompatible and positive crossmatch barriers
    Daniel S Warren
    The Department of Surgery, The Johns Hopkins University School of Medicine, Balitmore, Maryland, USA
    Am J Transplant 4:561-8. 2004
    ..The ability to cross these two barriers simultaneously is clinically important as sensitized patients have often exhausted their blood type compatible living donors during previous transplants...