Mouen A Khashab


Affiliation: Johns Hopkins University
Country: USA


  1. Brewer Gutierrez O, Khashab M. Stent Placement for the Treatment of Gastroparesis. Gastrointest Endosc Clin N Am. 2019;29:107-115 pubmed publisher
    ..These include transpyloric stenting, used for inpatients with refractory symptoms to allow hospital discharge or as a triage to assess symptoms response in patients considered for more definite therapies such as pyloromyotomy. ..
  2. Sinha A, Cader R, Akshintala V, Hutfless S, Zaheer A, Khan V, et al. Systemic inflammatory response syndrome between 24 and 48 h after ERCP predicts prolonged length of stay in patients with post-ERCP pancreatitis: a retrospective study. Pancreatology. 2015;15:105-10 pubmed publisher
    ..SIRS between 24 and 48 h after ERCP is an accurate, easy to obtain, and inexpensive predictor of severe PEP. PS is associated with a decreased prevalence of SIRS between 24 and 48 h after ERCP. ..
  3. Chen Y, Barkun A, Adam V, Bai G, Singh V, Bukhari M, et al. Cost-Effectiveness Analysis Comparing Lumen Apposing Metal Stents with Plastic Stents in the Management of Pancreatic Walled-Off Necrosis. Gastrointest Endosc. 2018;: pubmed publisher
    ..LAMSs are more effective but also more costly than PSs in managing WON. Data from high-quality adequately controlled prospective randomized trials are needed to confirm our findings. ..
  4. Khashab M, Alawad A, Shin E, Kim K, Bourdel N, Singh V, et al. Enteral stenting versus gastrojejunostomy for palliation of malignant gastric outlet obstruction. Surg Endosc. 2013;27:2068-75 pubmed publisher
    ..35, p = 0.03) were associated with significantly longer duration of oral intake after ES or GJ. ES is associated with fewer complications, shorter LOHS, but higher reintervention rates and overall charges. ..
  5. Ngamruengphong S, von Rahden B, Filser J, Tyberg A, Desai A, Sharaiha R, et al. Intraoperative measurement of esophagogastric junction cross-sectional area by impedance planimetry correlates with clinical outcomes of peroral endoscopic myotomy for achalasia: a multicenter study. Surg Endosc. 2016;30:2886-94 pubmed publisher
    ..Intraoperative EGJ cross-sectional area during POEM for achalasia correlated with clinical response and post-procedure reflux. Impedance planimetry is a potentially important tool to guide the extent and adequacy of myotomy during POEM. ..
  6. Ngamruengphong S, Pohl H, Haito Chavez Y, Khashab M. Update on Difficult Polypectomy Techniques. Curr Gastroenterol Rep. 2016;18:3 pubmed publisher
    ..In this article, we review the recent literature on the endoscopic management of difficult colorectal neoplasms. ..
  7. Saxena P, Khashab M. New NOTES Clinical Training and Program Development. Gastrointest Endosc Clin N Am. 2016;26:385-400 pubmed publisher
    ..Few institutions worldwide can provide all the cognitive and technical elements essential to train new NOTES trainees. Trainees may need to spend time across several institutions to ensure safe and effective practice of new NOTES. ..
  8. Parsa N, Khashab M. POEM in the Treatment of Esophageal Disorders. Curr Treat Options Gastroenterol. 2018;16:27-40 pubmed publisher
    ..POEM is a validated treatment for all patients with achalasia and SED. Candidates should be carefully selected and appropriately counseled on expected outcomes and the need for long-term surveillance. ..
  9. Khashab M, Benias P, Swanstrom L. Endoscopic Myotomy for Foregut Motility Disorders. Gastroenterology. 2018;154:1901-1910 pubmed publisher
    ..Last, the role of gastric POEM (G-POEM) in the treatment of gastroparesis has been investigated in recent studies with promising results. ..

More Information


  1. Khan M, Kumbhari V, Ngamruengphong S, Ismail A, Chen Y, Chavez Y, et al. Is POEM the Answer for Management of Spastic Esophageal Disorders? A Systematic Review and Meta-Analysis. Dig Dis Sci. 2017;62:35-44 pubmed publisher
    ..There was no difference in safety of POEM among individual SEDs. POEM is an effective and safe therapeutic modality for the treatment of spastic esophageal disorders. ..
  2. Saxena P, Khashab M. Endoscopic Management of Esophageal Perforations: Who, When, and How?. Curr Treat Options Gastroenterol. 2017;15:35-45 pubmed publisher
    ..If the perforation is associated with a mediastinal collection, drainage is mandatory and can be done via CT-guided percutaneous drainage, surgery, or endoscopic vacuum therapy. ..
  3. Ngamruengphong S, Inoue H, Ujiki M, Patel L, Bapaye A, Desai P, et al. Efficacy and Safety of Peroral Endoscopic Myotomy for Treatment of Achalasia After Failed Heller Myotomy. Clin Gastroenterol Hepatol. 2017;15:1531-1537.e3 pubmed publisher
    ..Although the rate of clinical success in patients with prior HM is lower than in those without prior HM, the safety profile of POEM is comparable between groups. ..
  4. Chen Y, Kunda R, Storm A, Aridi H, Thompson C, Nieto J, et al. EUS-guided gastroenterostomy: a multicenter study comparing the direct and balloon-assisted techniques. Gastrointest Endosc. 2017;: pubmed publisher
    ..The direct technique may be the preferred method given its shorter procedure time when compared with balloon-assisted approach. Prospective trials are needed to confirm these findings. ..
  5. Benias P, Khashab M. Gastric Peroral Endoscopic Pyloromyotomy Therapy for Refractory Gastroparesis. Curr Treat Options Gastroenterol. 2017;15:637-647 pubmed publisher
    ..Summary We believe that with proper patient selection, G-POEM will become a powerful tool for gastroenterologists managing this chronic debilitating disease. ..
  6. Brewer Gutierrez O, Bekkali N, Raijman I, Sturgess R, Sejpal D, Aridi H, et al. Efficacy and Safety of Digital Single-Operator Cholangioscopy for Difficult Biliary Stones. Clin Gastroenterol Hepatol. 2018;16:918-926.e1 pubmed publisher
    ..Fewer than 5% of patients require additional treatment with surgery and/or extracorporeal shockwave lithotripsy to clear the duct. ..