Sanjay Keswani

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Don't throw in the towel! A case of reversible coma
    S C Keswani
    Department of Neurology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Neurol Neurosurg Psychiatry 73:83-4. 2002
  2. pmc Antiphospholipid syndrome
    Sanjay C Keswani
    Department of Neurology, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J R Soc Med 95:336-42. 2002
  3. ncbi request reprint A case of splanchnic steal syndrome?
    Sanjay C Keswani
    Department of Neurology, The Johns Hopkins Hospital, Baltimore, Maryland, MD 21287, USA
    Lancet Neurol 2:379. 2003
  4. ncbi request reprint Erythropoietin is neuroprotective in models of HIV sensory neuropathy
    Sanjay C Keswani
    Department of Neurology, The Johns Hopkins Hospital, 600 North Wolfe Street, Pathology 627A, Baltimore, MD 21287, USA
    Neurosci Lett 371:102-5. 2004
  5. ncbi request reprint A novel endogenous erythropoietin mediated pathway prevents axonal degeneration
    Sanjay C Keswani
    Department of Neurology, The Johns Hopkins Hospital, Baltimore, MD, USA
    Ann Neurol 56:815-26. 2004
  6. ncbi request reprint Spatially distinct and functionally independent mechanisms of axonal degeneration in a model of HIV-associated sensory neuropathy
    Giorgia Melli
    Department of Neurology, Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Brain 129:1330-8. 2006
  7. ncbi request reprint Neuroprotection in the PNS: erythropoietin and immunophilin ligands
    Ahmet Hoke
    Department of Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Path 509, Baltimore, Maryland 21287, USA
    Ann N Y Acad Sci 1053:491-501. 2005
  8. ncbi request reprint Etiology of perfusion-diffusion magnetic resonance imaging mismatch patterns
    Lucas Restrepo
    Department of Neurology, Johns Hopkins Hospital, Baltimore, MD, USA
    J Neuroimaging 15:254-60. 2005
  9. ncbi request reprint The use of GAP-43 mRNA quantification in high throughput screening of putative neuroprotective agents in dorsal root ganglion cultures
    Sanjay C Keswani
    Department of Neurology, Johns Hopkins University, 600 N Wolfe St, Path 509, Baltimore, MD 21287, USA
    J Neurosci Methods 136:193-5. 2004
  10. ncbi request reprint Schwann cell chemokine receptors mediate HIV-1 gp120 toxicity to sensory neurons
    Sanjay C Keswani
    Department of Neurology, The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Ann Neurol 54:287-96. 2003

Research Grants

Collaborators

Detail Information

Publications17

  1. pmc Don't throw in the towel! A case of reversible coma
    S C Keswani
    Department of Neurology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Neurol Neurosurg Psychiatry 73:83-4. 2002
    ..With antihypertensive and supportive treatment, she recovered rapidly, and had no abnormalities on repeat imaging...
  2. pmc Antiphospholipid syndrome
    Sanjay C Keswani
    Department of Neurology, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J R Soc Med 95:336-42. 2002
  3. ncbi request reprint A case of splanchnic steal syndrome?
    Sanjay C Keswani
    Department of Neurology, The Johns Hopkins Hospital, Baltimore, Maryland, MD 21287, USA
    Lancet Neurol 2:379. 2003
  4. ncbi request reprint Erythropoietin is neuroprotective in models of HIV sensory neuropathy
    Sanjay C Keswani
    Department of Neurology, The Johns Hopkins Hospital, 600 North Wolfe Street, Pathology 627A, Baltimore, MD 21287, USA
    Neurosci Lett 371:102-5. 2004
    ..Our results suggest that EPO may be useful in the treatment of HIV-SN...
  5. ncbi request reprint A novel endogenous erythropoietin mediated pathway prevents axonal degeneration
    Sanjay C Keswani
    Department of Neurology, The Johns Hopkins Hospital, Baltimore, MD, USA
    Ann Neurol 56:815-26. 2004
    ..Our in vivo and in vitro data suggest that EPO prevents axonal degeneration and therefore may be therapeutically useful in a wide variety of human neurological diseases characterized by axonopathy...
  6. ncbi request reprint Spatially distinct and functionally independent mechanisms of axonal degeneration in a model of HIV-associated sensory neuropathy
    Giorgia Melli
    Department of Neurology, Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Brain 129:1330-8. 2006
    ..Furthermore, chemokine receptor inhibitors, which are currently being developed as HIV entry inhibitor drugs, may also have a therapeutic role in HIV-associated peripheral neuropathies by preventing axonal degeneration...
  7. ncbi request reprint Neuroprotection in the PNS: erythropoietin and immunophilin ligands
    Ahmet Hoke
    Department of Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Path 509, Baltimore, Maryland 21287, USA
    Ann N Y Acad Sci 1053:491-501. 2005
    ..Both EPO and non-immunosuppressive immunophilin ligands are in early clinical development for the treatment of acquired peripheral neuropathies...
  8. ncbi request reprint Etiology of perfusion-diffusion magnetic resonance imaging mismatch patterns
    Lucas Restrepo
    Department of Neurology, Johns Hopkins Hospital, Baltimore, MD, USA
    J Neuroimaging 15:254-60. 2005
    ..The authors therefore investigated the etiology of brain ischemia in patients with different DWI/PWI patterns...
  9. ncbi request reprint The use of GAP-43 mRNA quantification in high throughput screening of putative neuroprotective agents in dorsal root ganglion cultures
    Sanjay C Keswani
    Department of Neurology, Johns Hopkins University, 600 N Wolfe St, Path 509, Baltimore, MD 21287, USA
    J Neurosci Methods 136:193-5. 2004
    ..This was prevented, in a dose-dependent manner, by co-administration of FK506. This assay, performed in a 96-well format, can easily be scaled for high throughput screening (HTS) using robotic systems...
  10. ncbi request reprint Schwann cell chemokine receptors mediate HIV-1 gp120 toxicity to sensory neurons
    Sanjay C Keswani
    Department of Neurology, The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Ann Neurol 54:287-96. 2003
    ..This newly described Schwann cell-neuron interaction may be pathogenically relevant not only in HIV-SN but also in other peripheral neuropathies...
  11. ncbi request reprint FK506 is neuroprotective in a model of antiretroviral toxic neuropathy
    Sanjay C Keswani
    Department of Neurology, The Johns Hopkins University, Baltimore, MD, USA
    Ann Neurol 53:57-64. 2003
    ....
  12. ncbi request reprint HIV-associated sensory neuropathies
    Sanjay C Keswani
    AIDS 16:2105-17. 2002
  13. ncbi request reprint Establishment of a rodent model of HIV-associated sensory neuropathy
    Sanjay C Keswani
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Neurosci 26:10299-304. 2006
    ..This model will be useful in examining mechanisms of distal axonal degeneration and testing potential neuroprotective compounds that may prevent development of the sensory neuropathy...
  14. ncbi request reprint Central pontine and extrapontine myelinolysis owing to disequilibrium syndrome
    Sanjay C Keswani
    J Child Neurol 19:79-80; author reply 80-1. 2004
  15. ncbi request reprint Incidence of and risk factors for HIV-associated distal sensory polyneuropathy
    Sanjay C Keswani
    Neurology 61:279; author reply 279-80. 2003
  16. pmc IL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitis
    Adam I Kaplin
    Department of Psychiatry and Behavioral Sciences, Bloomberg School of Public Health, Baltimore, Maryland, USA
    J Clin Invest 115:2731-41. 2005
    ..The elucidation of this pathway identifies specific therapeutic targets in the management of CNS autoimmune conditions...
  17. ncbi request reprint Demyelinating disorders: update on transverse myelitis
    Chitra Krishnan
    Department of Neurology, Johns Hopkins University School of Medicine, Pathology 627, 600 North Wolfe Street, Baltimore, MD 21287 6965, USA
    Curr Neurol Neurosci Rep 6:236-43. 2006
    ..Clinical trials testing the efficacy of promising axonoprotective agents in combination with intravenous steroids in the treatment of TM are currently underway...

Research Grants2

  1. Peripheral neurotoxicity by the HIV-1 coat protein gp120
    Sanjay Keswani; Fiscal Year: 2005
    ..A major strength of our proposal is our use of human tissues to study a disease that only affects humans. ..