Wen Hong Linda Kao

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. pmc Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations
    W H Linda Kao
    Department of Epidemiology, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA
    Circulation 119:940-51. 2009
  2. pmc Does genetic ancestry explain higher values of glycated hemoglobin in African Americans?
    Nisa M Maruthur
    Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Diabetes 60:2434-8. 2011
  3. pmc African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts
    Ching Yu Cheng
    Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 7:e32840. 2012
  4. pmc Genetic variation of glucose transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) study
    Charles C Hsu
    Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    BMC Med Genet 12:16. 2011
  5. pmc Association of APOE polymorphism with chronic kidney disease in a nationally representative sample: a Third National Health and Nutrition Examination Survey (NHANES III) Genetic Study
    Audrey Y Chu
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    BMC Med Genet 10:108. 2009
  6. pmc Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies
    Anna Kottgen
    Department of Epidemiology and Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD, USA
    BMC Med Genet 9:49. 2008
  7. pmc The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts
    Jan Bressler
    Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    BMC Med Genet 10:56. 2009
  8. ncbi request reprint Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study
    W H Linda Kao
    Department of Epidemiology, The Johns Hopkins University School of Hygiene and Public Health, 615 N Wolfe Street, Room W6513, Baltimore, MD 21205, USA
    Diabetes 52:1568-72. 2003
  9. pmc MYH9 is associated with nondiabetic end-stage renal disease in African Americans
    W H Linda Kao
    Department of Epidemiology, School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Nat Genet 40:1185-92. 2008
  10. pmc Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate
    Adrienne Tin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Hum Genet 58:461-6. 2013

Research Grants

Detail Information

Publications49

  1. pmc Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations
    W H Linda Kao
    Department of Epidemiology, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA
    Circulation 119:940-51. 2009
    ....
  2. pmc Does genetic ancestry explain higher values of glycated hemoglobin in African Americans?
    Nisa M Maruthur
    Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Diabetes 60:2434-8. 2011
    ..We investigated the relative contribution of genetic ancestry and nongenetic factors to HbA(1c) values and the effect of genetic ancestry on diabetes classification by HbA(1c) in African Americans...
  3. pmc African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts
    Ching Yu Cheng
    Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 7:e32840. 2012
    ..There undoubtedly is a complex interplay among specific genetic loci and non-genetic factors, which may both be associated with overall admixture, leading to the observed ethnic differences in diabetes risk...
  4. pmc Genetic variation of glucose transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) study
    Charles C Hsu
    Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    BMC Med Genet 12:16. 2011
    ..Our aim was to evaluate associations with albuminuria of six GLUT1 single nucleotide polymorphisms(SNPs), particularly XbaI and the previously associated Enhancer-2 (Enh2) SNP...
  5. pmc Association of APOE polymorphism with chronic kidney disease in a nationally representative sample: a Third National Health and Nutrition Examination Survey (NHANES III) Genetic Study
    Audrey Y Chu
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    BMC Med Genet 10:108. 2009
    ..However, few data are available in non-European ethnic groups or in a population-based cohort...
  6. pmc Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies
    Anna Kottgen
    Department of Epidemiology and Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD, USA
    BMC Med Genet 9:49. 2008
    ..The study of 70,987 single nucleotide polymorphisms (SNPs) in 1,010 FHS participants provides a list of SNPs showing the strongest associations with renal traits which need to be verified in independent study samples...
  7. pmc The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts
    Jan Bressler
    Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    BMC Med Genet 10:56. 2009
    ..The combined study sample is comprised of 24,722 white, African-American, and Mexican-American participants...
  8. ncbi request reprint Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study
    W H Linda Kao
    Department of Epidemiology, The Johns Hopkins University School of Hygiene and Public Health, 615 N Wolfe Street, Room W6513, Baltimore, MD 21205, USA
    Diabetes 52:1568-72. 2003
    ..We conclude that among nonobese African Americans, the Pro/Ala genotype is associated with markers of greater insulin sensitivity...
  9. pmc MYH9 is associated with nondiabetic end-stage renal disease in African Americans
    W H Linda Kao
    Department of Epidemiology, School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Nat Genet 40:1185-92. 2008
    ....
  10. pmc Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate
    Adrienne Tin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Hum Genet 58:461-6. 2013
    ..However, careful attention must be paid to the correlation of systematic errors and inconsistent associations when different biomarkers or methods are used to measure the quantitative trait. ..
  11. doi request reprint Association between variants in or near PNPLA3, GCKR, and PPP1R3B with ultrasound-defined steatosis based on data from the third National Health and Nutrition Examination Survey
    Ruben Hernaez
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Clin Gastroenterol Hepatol 11:1183-1190.e2. 2013
    ....
  12. pmc Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study
    Ching Yu Cheng
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Obesity (Silver Spring) 18:563-72. 2010
    ..92 kg/m(2) (P = 2.9 x 10(-5)). Further mapping in this region on chromosome 2 may be able to uncover causative variants underlying obesity, which may offer insights into the control of energy homeostasis...
  13. ncbi request reprint Haplotype of signal transducer and activator of transcription 3 gene predicts cardiovascular disease in dialysis patients
    Lin Zhang
    Department of Epidemiology, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Am Soc Nephrol 17:2285-92. 2006
    ..008). Variation in the STAT3 gene is associated with the risk for CVD among white dialysis patients independent of serum IL-6 and CRP levels...
  14. ncbi request reprint SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study
    Michael J Garant
    Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    Diabetes 51:231-7. 2002
    ..We conclude from this large prospective study that the G allele of SNP43 of CAPN10 or another allele or gene that is in linkage disequilibrium with it increases susceptibility to type 2 diabetes in African-Americans...
  15. pmc Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele
    Adrienne Tin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Hum Mol Genet 20:4056-68. 2011
    ..Our data support the importance of multi-ethnic GWAS in the identification of novel risk loci as well as functional variants...
  16. pmc SLCO1B1 variants and urine arsenic metabolites in the Strong Heart Family Study
    Matthew O Gribble
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205
    Toxicol Sci 136:19-25. 2013
    ..Replication of this finding in other populations and analyses with respect to disease outcomes are needed to determine whether this novel candidate gene is important for arsenic-associated disease risks. ..
  17. pmc Association of scavenger receptor class B type I polymorphisms with subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis
    Adam C Naj
    Department of Medicine, School of Medicine, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD, USA
    Circ Cardiovasc Genet 3:47-52. 2010
    ..We examined this relationship in the Multi-Ethnic Study of Atherosclerosis...
  18. pmc Association of single-nucleotide polymorphisms in JAK3, STAT4, and STAT6 with new cardiovascular events in incident dialysis patients
    C John Sperati
    Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Am J Kidney Dis 53:845-55. 2009
    ....
  19. pmc Association between parental history of type 2 diabetes and glycemic control in urban African Americans
    Lucy Gong
    Department of Epidemiology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Diabetes Care 31:1773-6. 2008
    ..The purpose of this study was to examine the association between parental history of type 2 diabetes and glycemic control among diabetic urban African Americans...
  20. pmc Hemochromatosis gene and nonalcoholic fatty liver disease: a systematic review and meta-analysis
    Ruben Hernaez
    Department of Medicine, Division of General Internal Medicine, The Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Hepatol 55:1079-85. 2011
    ..The goal of this study was to systematically evaluate and summarize data on the association between these two variants and the presence of NAFLD...
  21. pmc Admixture mapping scans identify a locus affecting retinal vascular caliber in hypertensive African Americans: the Atherosclerosis Risk in Communities (ARIC) study
    Ching Yu Cheng
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
    PLoS Genet 6:e1000908. 2010
    ..001). Further mapping in the 6p21.1 region may uncover novel genetic variants affecting retinal vascular caliber and further insights into the interaction between genetic effects of the microvascular system and hypertension...
  22. pmc Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X
    Ching Yu Cheng
    Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA
    PLoS Genet 5:e1000490. 2009
    ..27; genome-wide score = 3.46). Further mapping studies with dense sets of markers will be necessary to identify the alleles in these regions of chromosomes X and 5 that may be associated with variation in BMI...
  23. pmc The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study
    Nora Franceschini
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Am J Hypertens 22:552-8. 2009
    ..The checkpoint 2 gene (CHEK2) is an important transducer in DNA damage signaling pathways in response to injury, and therefore, CHEK2 variants may affect susceptibility to kidney disease...
  24. ncbi request reprint Increased risk of type 2 diabetes from a family history of coronary heart disease and type 2 diabetes
    Edwina H Yeung
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    Diabetes Care 30:154-6. 2007
  25. ncbi request reprint Coffee and sweetened beverage consumption and the risk of type 2 diabetes mellitus: the atherosclerosis risk in communities study
    Nina P Paynter
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Epidemiol 164:1075-84. 2006
    ..In summary, increased coffee consumption was significantly associated with a decreased risk of diagnosed type 2 diabetes mellitus in community-based US adults...
  26. pmc Incidental findings on cardiac computed tomography in incident hemodialysis patients: the predictors of arrhythmic and cardiovascular events in end-stage renal disease (PACE) study
    Bernard G Jaar
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
    BMC Nephrol 15:68. 2014
    ..This is the first study that has examined non-cardiac incidental findings in research cardiac computed tomography (CT) of hemodialysis patients and their relationship with patient characteristics...
  27. pmc Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin
    Adrienne Tin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Hum Genet 132:619-27. 2013
    ..The identification of the two novel loci for B2M extends our understanding of its metabolism and informs its use as a kidney filtration biomarker...
  28. pmc Evaluation of a novel isotope biomarker for dietary consumption of sweets
    Edwina H Yeung
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Am J Epidemiol 172:1045-52. 2010
    ..Within the proper framework, serum δ¹³C value could be developed into an objective biomarker promoting more reliable assessment of dietary sweets intake...
  29. ncbi request reprint Type 2 diabetes is associated with increased bone mineral density in Mexican-American women
    W H Linda Kao
    Department of Epidemiology, The Johns Hopkins University, Baltimore, MD, USA
    Arch Med Res 34:399-406. 2003
    ..Our purpose was to determine whether type 2 diabetes is associated with altered bone mineral density (BMD) and whether fasting serum insulin levels are correlated with BMD...
  30. pmc Multiple loci associated with indices of renal function and chronic kidney disease
    Anna Kottgen
    Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA
    Nat Genet 41:712-7. 2009
    ..Our findings provide new insights into CKD pathogenesis and underscore the importance of common genetic variants influencing renal function and disease...
  31. pmc TCF7L2 variants associate with CKD progression and renal function in population-based cohorts
    Anna Kottgen
    Department of Epidemiology and Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, Maryland, USA
    J Am Soc Nephrol 19:1989-99. 2008
    ..In conclusion, several population-based samples suggest that variants in the TCF7L2 gene are associated with reduced kidney function or CKD progression, overall and specifically among participants without diabetes...
  32. ncbi request reprint Apolipoprotein E and progression of chronic kidney disease
    Charles C Hsu
    Department of Epidemiology, The Welch Center for Prevention, Epidemiology, and Clinical Research, The Johns Hopkins Medical Institutions, Baltimore, MD 21205 2223, USA
    JAMA 293:2892-9. 2005
    ..APOE allelic associations with chronic kidney disease beyond diabetic nephropathy are unknown, with no studies reported in high-risk African American populations...
  33. ncbi request reprint Associations between total serum IgE levels and the 6 potentially functional variants within the genes IL4, IL13, and IL4RA in German children: the German Multicenter Atopy Study
    Xin Liu
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Allergy Clin Immunol 112:382-8. 2003
    ....
  34. ncbi request reprint A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization
    Dan E Arking
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nat Genet 38:644-51. 2006
    ..Approximately 60% of subjects of European ancestry carry at least one minor allele of the NOS1AP genetic variant, which explains up to 1.5% of QT interval variation...
  35. ncbi request reprint Short stature and the risk of adiposity, insulin resistance, and type 2 diabetes in middle age: the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994
    Keiko Asao
    Department of Epidemiology, Johns Hopkins University, Baltimore, MD 21205, USA
    Diabetes Care 29:1632-7. 2006
    ..To investigate the association between stature-related measurements (height, leg length, and leg length-to-height ratio) and adiposity, insulin resistance, and glucose intolerance...
  36. pmc Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the old order Amish
    Wendy Post
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    Hum Hered 64:214-9. 2007
    ..The purpose of the current study was to replicate this association in the Old Order Amish...
  37. pmc Age and sex disparities in discussions about kidney transplantation in adults undergoing dialysis
    Megan L Salter
    Department of Epidemiology, School of Public Health, Johns Hopkins University, Baltimore, Maryland Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland
    J Am Geriatr Soc 62:843-9. 2014
    ..To explore whether disparities in age and sex in access to kidney transplantation (KT) originate at the time of prereferral discussions about KT...
  38. ncbi request reprint Preferences, knowledge, communication and patient-physician discussion of living kidney transplantation in African American families
    L Ebony Boulware
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Am J Transplant 5:1503-12. 2005
    ....
  39. doi request reprint The association of sudden cardiac death with inflammation and other traditional risk factors
    Rulan S Parekh
    Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Kidney Int 74:1335-42. 2008
    ..Hence, we found that sudden cardiac death is common among patients with end stage renal disease and that inflammation and malnutrition significantly increased its occurrence independent of traditional cardiovascular risk factors...
  40. pmc The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults
    Anna Kottgen
    Johns Hopkins University, Baltimore, MD, USA
    Am J Kidney Dis 52:868-75. 2008
    ....
  41. ncbi request reprint Family history of type 2 diabetes is associated with increased carotid artery intimal-medial thickness in Mexican Americans
    W H Linda Kao
    Department of Epidemiology, Bloomberg School of Public Health, John s Hopkins University, Baltimore, Maryland, USA
    Diabetes Care 28:1882-9. 2005
    ..To evaluate whether the joint risk of diabetes and atherosclerosis tracked within families, we assessed the correlation between a family history of diabetes and intimal-medial thickness (IMT) of the common carotid artery (CCA)...
  42. ncbi request reprint Genetic variation of the renin-angiotensin system and chronic kidney disease progression in black individuals in the atherosclerosis risk in communities study
    Charles Chia Chuen Hsu
    Department of Epidemiology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    J Am Soc Nephrol 17:504-12. 2006
    ..The AT1R C1166 allele may increase susceptibility but only in the presence of hypertension...
  43. ncbi request reprint Comparison of SNP tagging methods using empirical data: association study of 713 SNPs on chromosome 12q14.3-12q24.21 for asthma and total serum IgE in an African Caribbean population
    Peter B Chi
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Genet Epidemiol 30:609-19. 2006
    ..We also found a high degree of consistency between TagSNP and Tagger. Using this set of 713 SNPs on chromosome 12q, our study provides insight towards analytic strategies for future studies of complex traits...
  44. ncbi request reprint Delayed diagnosis of incident type 2 diabetes mellitus in the ARIC study
    T Alafia Samuels
    Department of Epidemiology, The Johns Hopkins University, Baltimore, MD, USA
    Am J Manag Care 12:717-24. 2006
    ..To estimate delays to physician diagnosis of incident cases of type 2 diabetes mellitus (DM) and to identify predictors of delayed diagnosis...
  45. ncbi request reprint Reliability of urinary albumin, total protein, and creatinine assays after prolonged storage: the Family Investigation of Nephropathy and Diabetes
    Rulan S Parekh
    Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Clin J Am Soc Nephrol 2:1156-62. 2007
    ....
  46. ncbi request reprint Pulmonary hypertension and risk of death in cardiomyopathy: patients with myocarditis are at higher risk
    Thomas P Cappola
    Department of Medicine, Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Circulation 105:1663-8. 2002
    ....
  47. ncbi request reprint Associations between specific serum IgE response and 6 variants within the genes IL4, IL13, and IL4RA in German children: the German Multicenter Atopy Study
    Xin Liu
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Allergy Clin Immunol 113:489-95. 2004
    ..SNPs were commonly considered individually, and therefore the true effect could be masked by other genes or environmental factors...
  48. ncbi request reprint Role of a proline insertion in the insulin promoter factor 1 (IPF1) gene in African Americans with type 2 diabetes
    Steven C Elbein
    Endocrinology Section, Central Arkansas Veterans Healthcare System, Little Rock, Arkansas, USA
    Diabetes 55:2909-14. 2006
    ..1). InsCCG243 does not act in a dominant, highly penetrant fashion in African Americans and is not a significant risk factor for type 2 diabetes in this population...
  49. ncbi request reprint Reliability of high-throughput genotyping of whole genome amplified DNA in SNP genotyping studies
    Yvette Berthier-Schaad
    Laboratory of Genomic Diversity, NCI Frederick, Frederick, MD, USA
    Electrophoresis 28:2812-7. 2007
    ..DNA amplification methodologies provide a useful solution for current and future large-scale genetic analyses especially with limited quantities of samples and DNA...

Research Grants4

  1. Genetic Epidemiology of NAFLD and T2DM
    Wen Hong Kao; Fiscal Year: 2007
    ..A deeper understanding of the molecular pathogenesis of obesity, IR, NAFLD, and T2DM may suggest new approaches for the prevention and treatment of these conditions. ..
  2. Admixture Mapping to Identify T2DM Genes in African Americans
    Wen Hong Kao; Fiscal Year: 2007
    ....
  3. Identification of Genes for ESRD in African Americans
    Wen Hong Kao; Fiscal Year: 2007
    ..This study will provide key insights into the genetic control of susceptibility of ESRD ..