Daniel P Judge

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. doi request reprint Mitral valve disease in Marfan syndrome and related disorders
    Daniel P Judge
    Division of Cardiology, Johns Hopkins University, Ross 1049 720 Rutland Avenue, Baltimore, MD 21205, USA
    J Cardiovasc Transl Res 4:741-7. 2011
  2. doi request reprint Pathophysiology and therapy of cardiac dysfunction in Duchenne muscular dystrophy
    Daniel P Judge
    Division of Cardiology Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Cardiovasc Drugs 11:287-94. 2011
  3. doi request reprint Genetic evaluation of familial cardiomyopathy
    Daniel P Judge
    Division of Cardiology, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 1049, Baltimore, MD 21205, USA
    J Cardiovasc Transl Res 1:144-54. 2008
  4. ncbi request reprint Use of genetics in the clinical evaluation and management of heart failure
    Daniel P Judge
    Center for Inherited Heart Disease, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 1049, Baltimore, MD, 21205, USA
    Curr Treat Options Cardiovasc Med 12:566-77. 2010
  5. doi request reprint Use of genetics in the clinical evaluation of cardiomyopathy
    Daniel P Judge
    Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    JAMA 302:2471-6. 2009
  6. pmc Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism
    Jennifer P Habashi
    Howard Hughes Medical Institute and Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 332:361-5. 2011
  7. doi request reprint Risk stratification in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated desmosomal mutation carriers
    Aditya Bhonsale
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD
    Circ Arrhythm Electrophysiol 6:569-78. 2013
  8. pmc Shared desmosome gene findings in early and late onset arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Boon Yew Tan
    Department of Medicine Cardiology, Johns Hopkins University School of Medicine, Rutland Avenue, Baltimore, MD 21205, USA
    J Cardiovasc Transl Res 3:663-73. 2010
  9. doi request reprint Incremental value of cardiac magnetic resonance imaging in arrhythmic risk stratification of arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated desmosomal mutation carriers
    Anneline S J M Te Riele
    Department of Medicine, Division of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
    J Am Coll Cardiol 62:1761-9. 2013
  10. pmc Recessive arrhythmogenic right ventricular dysplasia due to novel cryptic splice mutation in PKP2
    Mark M Awad
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Hum Mutat 27:1157. 2006

Detail Information

Publications50

  1. doi request reprint Mitral valve disease in Marfan syndrome and related disorders
    Daniel P Judge
    Division of Cardiology, Johns Hopkins University, Ross 1049 720 Rutland Avenue, Baltimore, MD 21205, USA
    J Cardiovasc Transl Res 4:741-7. 2011
    ....
  2. doi request reprint Pathophysiology and therapy of cardiac dysfunction in Duchenne muscular dystrophy
    Daniel P Judge
    Division of Cardiology Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Cardiovasc Drugs 11:287-94. 2011
    ..This article focuses on mechanisms of cardiac dysfunction, as well as potential targets for pharmacologic manipulation to prevent or improve cardiomyopathy in DMD...
  3. doi request reprint Genetic evaluation of familial cardiomyopathy
    Daniel P Judge
    Division of Cardiology, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 1049, Baltimore, MD 21205, USA
    J Cardiovasc Transl Res 1:144-54. 2008
    ..This review will focus on inherited forms of cardiomyopathy, detailing the currently available genetic tests, as well as benefits, limitations, and possible outcomes of such testing...
  4. ncbi request reprint Use of genetics in the clinical evaluation and management of heart failure
    Daniel P Judge
    Center for Inherited Heart Disease, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 1049, Baltimore, MD, 21205, USA
    Curr Treat Options Cardiovasc Med 12:566-77. 2010
    ..Because of its complexity and the rapid rate of change in available genetic testing options, the genetic evaluation of heart failure is best suited to tertiary referral centers with specific expertise in this area...
  5. doi request reprint Use of genetics in the clinical evaluation of cardiomyopathy
    Daniel P Judge
    Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    JAMA 302:2471-6. 2009
    ..With or without genetic testing, screening of family members who are at risk for an inherited form of cardiomyopathy leads to earlier identification, earlier treatment, and improved outcomes...
  6. pmc Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism
    Jennifer P Habashi
    Howard Hughes Medical Institute and Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 332:361-5. 2011
    ..These data highlight the protective nature of AT2 signaling and potentially inform the choice of therapies in MFS and related disorders...
  7. doi request reprint Risk stratification in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated desmosomal mutation carriers
    Aditya Bhonsale
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD
    Circ Arrhythm Electrophysiol 6:569-78. 2013
    ..We investigated the role of phenotypic characteristics in stratifying the risk of sustained ventricular arrhythmias in patients harboring arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated mutations...
  8. pmc Shared desmosome gene findings in early and late onset arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Boon Yew Tan
    Department of Medicine Cardiology, Johns Hopkins University School of Medicine, Rutland Avenue, Baltimore, MD 21205, USA
    J Cardiovasc Transl Res 3:663-73. 2010
    ..027). The presence of these variants did not associate with the age of onset of ARVD/C or ventricular tachycardia. These findings highlight the complex interplay of environmental and genetic factors contributing to this condition...
  9. doi request reprint Incremental value of cardiac magnetic resonance imaging in arrhythmic risk stratification of arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated desmosomal mutation carriers
    Anneline S J M Te Riele
    Department of Medicine, Division of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
    J Am Coll Cardiol 62:1761-9. 2013
    ....
  10. pmc Recessive arrhythmogenic right ventricular dysplasia due to novel cryptic splice mutation in PKP2
    Mark M Awad
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Hum Mutat 27:1157. 2006
    ..The possibility of cryptic or alternative splicing should be considered with identification of apparently synonymous nucleotide substitutions in this gene...
  11. pmc Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states
    Ronald D Cohn
    McKusick Nathans Institute of Genetic Medicine, Baltimore, Maryland 21205, USA
    Nat Med 13:204-10. 2007
    ..Moreover, we show TGF-beta-induced failure of muscle regeneration and a similar therapeutic response in a dystrophin-deficient mouse model of Duchenne muscular dystrophy...
  12. ncbi request reprint Penetrance of mutations in plakophilin-2 among families with arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Darshan Dalal
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Am Coll Cardiol 48:1416-24. 2006
    ....
  13. pmc Exercise increases age-related penetrance and arrhythmic risk in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated desmosomal mutation carriers
    Cynthia A James
    Department of Medicine, Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland Electronic address
    J Am Coll Cardiol 62:1290-7. 2013
    ..This study sought to determine how exercise influences penetrance of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) among patients with desmosomal mutations...
  14. doi request reprint Outcomes of catheter ablation of ventricular tachycardia in arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Binu Philips
    Division of Cardiology, Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Circ Arrhythm Electrophysiol 5:499-505. 2012
    ..The overall objective of the present study was to assess the efficacy of radiofrequency catheter ablation (RFA) of VT in ARVD/C, with particular focus on newer ablation strategies, including epicardial catheter ablation...
  15. pmc Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice
    Tammy M Holm
    Howard Hughes Medical Institute and Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 332:358-61. 2011
    ..Thus, noncanonical (Smad-independent) TGFβ signaling is a prominent driver of aortic disease in MFS mice, and inhibition of the ERK1/2 or JNK1 pathways is a potential therapeutic strategy for the disease...
  16. ncbi request reprint The variable natural history of idiopathic dilated cardiomyopathy
    Kapil Parakh
    Department of Medicine, Johns Hopkins Bayview Medical Center, Baltimore, MD, USA
    Isr Med Assoc J 14:666-71. 2012
    ..The relative value of traditional prognostic criteria remains unclear and the assessment of long-term prognosis for individual patients is problematic...
  17. doi request reprint Reader- and instrument-dependent variability in the electrocardiographic assessment of arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Rahul Jain
    Department of Medicine Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 22:561-8. 2011
    ..This study was aimed at examining the variability in the ECG interpretation resulting from the same reader, different readers, and using different ECG-resolutions...
  18. doi request reprint Mutation-positive arrhythmogenic right ventricular dysplasia/cardiomyopathy: the triangle of dysplasia displaced
    Anneline S J M Te Riele
    Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Cardiovasc Electrophysiol 24:1311-20. 2013
    ..The traditional description of the Triangle of Dysplasia in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) predates genetic testing and excludes biventricular phenotypes...
  19. doi request reprint Morphologic variants of familial arrhythmogenic right ventricular dysplasia/cardiomyopathy a genetics-magnetic resonance imaging correlation study
    Darshan Dalal
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Coll Cardiol 53:1289-99. 2009
    ....
  20. pmc Comprehensive desmosome mutation analysis in north americans with arrhythmogenic right ventricular dysplasia/cardiomyopathy
    A Dénise den Haan
    Department of Medicine Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Circ Cardiovasc Genet 2:428-35. 2009
    ..We report comprehensive desmosome genetic analysis for 100 North Americans with clinically confirmed or suspected ARVD/C...
  21. pmc Prolonged RV endocardial activation duration: a novel marker of arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Harikrishna Tandri
    Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Heart Rhythm 6:769-75. 2009
    ..Parietal block, defined as intra right ventricular (RV) conduction slowing, is a major diagnostic criterion for arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C)...
  22. pmc Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome
    Jennifer P Habashi
    Howard Hughes Medical Institute and Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 312:117-21. 2006
    ....
  23. pmc Angiotensin II blockade and aortic-root dilation in Marfan's syndrome
    Benjamin S Brooke
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    N Engl J Med 358:2787-95. 2008
    ..We evaluated the clinical response to ARBs in pediatric patients with Marfan's syndrome who had severe aortic-root enlargement...
  24. doi request reprint Exercise testing in asymptomatic gene carriers exposes a latent electrical substrate of arrhythmogenic right ventricular cardiomyopathy
    Mark J Perrin
    Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 62:1772-9. 2013
    ..The aim of this study was to determine if exercise testing could expose a latent electrical substrate of arrhythmogenic right ventricular cardiomyopathy (ARVC) in asymptomatic gene carriers...
  25. doi request reprint A family with a complex clinical presentation characterized by arrhythmogenic right ventricular dysplasia/cardiomyopathy and features of branchio-oculo-facial syndrome
    Brittney Murray
    Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
    Am J Med Genet A 161:371-6. 2013
    ..Finally, it suggests that individuals with unexplained cardiomyopathy and dysmorphic facial features may benefit from CMA analysis...
  26. pmc The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance
    Radwa A Noureldin
    Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:17. 2012
    ..It is likely that integrating genetic advances with enhanced phenotypic characterization of HCM with novel CMR techniques will importantly improve our understanding of this complex disease...
  27. pmc TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome
    Connie M Ng
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Clin Invest 114:1586-92. 2004
    ....
  28. ncbi request reprint Long-term efficacy of catheter ablation of ventricular tachycardia in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Darshan Dalal
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Coll Cardiol 50:432-40. 2007
    ..Particular focus was placed on defining the single-procedure efficacy over long-term follow-up...
  29. ncbi request reprint The benefit of upgrading chronically right ventricle-paced heart failure patients to resynchronization therapy demonstrated by strain rate imaging
    Zayd A Eldadah
    Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Heart Rhythm 3:435-42. 2006
    ..RV pacing induces conduction delay (CD), mechanical dyssynchrony, and increased morbidity in patients with HF. CRT improves HF symptoms and survival, but sparse data exist on its direct effect on chronically RV-paced HF patients...
  30. doi request reprint The change in B-type natriuretic peptide levels over time predicts significant rejection in cardiac transplant recipients
    Michelle M Kittleson
    Department of Medicine, Division of Cardiology, University of California at Los Angeles, Los Angeles, California, USA
    J Heart Lung Transplant 28:704-9. 2009
    ....
  31. pmc Mechanisms of disease: molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Mark M Awad
    Johns Hopkins University School of Medicine and Johns Hopkins University Cellular and Molecular Medicine Program, Baltimore, MD, USA
    Nat Clin Pract Cardiovasc Med 5:258-67. 2008
    ....
  32. pmc Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome
    Daniel P Judge
    Division of Cardiology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Clin Invest 114:172-81. 2004
    ..In keeping with this model, introduction of a WT FBN1 transgene on a heterozygous C1039G background rescues aortic phenotype...
  33. doi request reprint Incidence and predictors of implantable cardioverter-defibrillator therapy in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy undergoing implantable cardioverter-defibrillator implantation for primary prevention
    Aditya Bhonsale
    Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Am Coll Cardiol 58:1485-96. 2011
    ....
  34. pmc DSG2 mutations contribute to arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Mark M Awad
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Am J Hum Genet 79:136-42. 2006
    ..We report that mutations in DSG2 contribute to the development of ARVD/C...
  35. doi request reprint Malignant arrhythmogenic right ventricular dysplasia/cardiomyopathy with a normal 12-lead electrocardiogram: a rare but underrecognized clinical entity
    Anneline S J M Te Riele
    Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland
    Heart Rhythm 10:1484-91. 2013
    ..In Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C), a normal electrocardiogram (ECG) is considered reassuring. However, some patients with ARVD/C experiencing ventricular arrhythmias have a normal ECG...
  36. ncbi request reprint Extensive cardiac allograft vasculitis and concurrent fat necrosis 6 years after orthotopic heart transplantation
    Jonathan D Cuda
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    J Heart Lung Transplant 26:1212-6. 2007
    ..The presence of the M2 macrophage phenotype supports transplant vasculitis as part of the chronic transplant vasculopathy continuum...
  37. ncbi request reprint Therapy of Marfan syndrome
    Daniel P Judge
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Annu Rev Med 59:43-59. 2008
    ..These results highlight the potential for development of targeted therapies based on discovery of disease genes and interrogation of pathogenesis in murine models...
  38. ncbi request reprint Use of a coronary sinus lead and biventricular ICD to correct a sensing abnormality in a patient with arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Kenneth C Bilchick
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 17:317-20. 2006
    ..We discuss how the use of a bipolar coronary sinus lead and a biventricular ICD generator with a novel header configuration solved the problem...
  39. ncbi request reprint Intracardiac giant cells after left ventricular assist device placement
    Hubert Fenton
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Heart Lung Transplant 26:417-20. 2007
    ..An awareness of this entity is important to avoid making a diagnosis of a more severe giant cell-related pathologic disease, which may recur in a transplanted heart...
  40. pmc Marfan's syndrome
    Daniel P Judge
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Lancet 366:1965-76. 2005
    ..Insights derived from studying this mendelian disorder are anticipated to have relevance for more common and non-syndromic presentations of selected aspects of the Marfan phenotype...
  41. pmc LMNA-associated cardiocutaneous progeria: an inherited autosomal dominant premature aging syndrome with late onset
    Megan S Kane
    Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Am J Med Genet A 161:1599-611. 2013
    ..Our findings advance knowledge of human LMNA progeria syndromes, and raise the possibility that typical and atypical progerias may converge upon a common mechanism to cause premature aging disease...
  42. doi request reprint Prospective evaluation of the morbidity and mortality of wild-type and V122I mutant transthyretin amyloid cardiomyopathy: the Transthyretin Amyloidosis Cardiac Study (TRACS)
    Frederick L Ruberg
    Amyloid Treatment and Research Program, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Am Heart J 164:222-228.e1. 2012
    ..Prospective data are lacking in the most common TTR mutation, V122I, present in approximately 3.5% of African Americans...
  43. ncbi request reprint Reversible cardiomyopathy caused by administration of interferon alpha
    Aarif Y Khakoo
    Division of Cardiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Nat Clin Pract Cardiovasc Med 2:53-7. 2005
    ..Physical examination findings were consistent with congestive heart failure. Laboratory studies were notable for hypothyroidism. Echocardiography revealed severe, global left-ventricular dysfunction...
  44. ncbi request reprint A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2
    Bart L Loeys
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Nat Genet 37:275-81. 2005
    ....
  45. ncbi request reprint Short-term effects of right-left heart sequential cardiac resynchronization in patients with heart failure, chronic atrial fibrillation, and atrioventricular nodal block
    Ilan Hay
    Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Circulation 110:3404-10. 2004
    ..Whether altering the site of stimulation can offset this detrimental effect and what role sequential right ventricular-left ventricular (RV-LV) stimulation might play in such patients remain unknown...
  46. ncbi request reprint Clinical features of arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in plakophilin-2
    Darshan Dalal
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Circulation 113:1641-9. 2006
    ..The purpose of our study was to validate the frequency of PKP2 mutations in another large series of ARVD/C patients and to examine the phenotypic characteristics associated with PKP2 mutations...
  47. pmc KLOTHO allele status and the risk of early-onset occult coronary artery disease
    Dan E Arking
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Am J Hum Genet 72:1154-61. 2003
    ..Modifiable risk factors, including hypertension, smoking status, and HDL-C level, appear to influence the risk imposed by this allele...
  48. ncbi request reprint Current treatment of adult Duchenne muscular dystrophy
    Kathryn R Wagner
    Department of Neurology, The Johns Hopkins School of Medicine, Meyer 5 119, 600 N Wolfe St, Baltimore, MD 21287, USA
    Biochim Biophys Acta 1772:229-37. 2007
    ..Current and future therapies directed at prolonging the lifespan of those with DMD will result in further increases in this adult population with special needs and concerns. These needs are best addressed in a multidisciplinary clinic...
  49. ncbi request reprint Arrhythmogenic right ventricular dysplasia: a United States experience
    Darshan Dalal
    Division of Cardiology, The Johns Hopins University School of Medicine, Baltimore, MD, USA
    Circulation 112:3823-32. 2005
    ..The purpose of our study was to describe the presentation, clinical features, survival, and natural history of ARVD in a large cohort of patients from the United States...
  50. ncbi request reprint Conductance catheter-based assessment of arterial input impedance, arterial function, and ventricular-vascular interaction in mice
    Patrick Segers
    Hydraulics Laboratory, Institute Biomedical Technology, Ghent University, Gent, Belgium
    Am J Physiol Heart Circ Physiol 288:H1157-64. 2005
    ..We obtained an anticipated response of Z(in) and arterial function parameters following VCO and AOO, demonstrating the sensitivity of the measuring technique to induced physiological alterations in murine hemodynamics...

Research Grants3

  1. Pathogenesis and Therapy of Marfan Vascular Disease
    Daniel Judge; Fiscal Year: 2007
    ..Dr. Judge's training will be based in the School of Public Health at Johns Hopkins, and he will be advised by a committee of experts to create a fruitful environment for the development of an independent clinical scientist. ..
  2. Genetic Investigation of Arrhythmogenic Right Ventricular Dysplasia
    Daniel Judge; Fiscal Year: 2007
    ..A more efficient type of genetic analysis will be tested. This will lead to better understanding of genetic susceptibility to sudden death from heart disease. ..