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Genomes and GenesSpecies | Alexander W JohnsonSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Dietary manipulations influence sucrose acceptance in diet induced obese miceAlexander W Johnson
Department of Psychological and Brain Sciences, Neurogenetics and Behavior Center, Johns Hopkins University, 3400 N Charles Street, Ames Hall, Room 101, Baltimore, MD 21218, USA
Appetite 58:215-21. 2012..As a result of this dietary switch, all mice showed comparable licking behavior suggesting that exposure to the high-fat diet and diet-induced obesity may reduce preferences for other tastants in C57BL/6J mice...
An analysis of licking microstructure in three strains of miceA W Johnson
Neurogenetics and Behavior Center, Department of Psychological and Brain Sciences, Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
Appetite 54:320-30. 2010..These differences in licking behavior might reflect influences of genetic background on pre- and post-ingestive factors controlling intake, the reinforcing properties of each tastant, or native differences in licking style...
Assessing the role of the growth hormone secretagogue receptor in motivational learning and food intakeAlexander W Johnson
Neurogenetics and Behavior Center, Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD, 21218, USA
Behav Neurosci 123:1058-65. 2009..These results suggest dissociable functions of GHS-R in its influence over motivational learning and ingestive behavior...
Localized disruption of Narp in medial prefrontal cortex blocks reinforcer devaluation performanceAlexander W Johnson
Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
Learn Mem 17:620-6. 2010..Thus, these results indicate that Narp released from mPFC neurons plays a key role in mediating synaptic changes underlying instrumental reinforcer devaluation...
The basolateral amygdala is critical to the expression of pavlovian and instrumental outcome-specific reinforcer devaluation effectsAlexander W Johnson
Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA
J Neurosci 29:696-704. 2009..Thus, BLA apparently plays a critical role in maintaining or using sensory associations of reinforcer value when multiple outcomes must be coded but not under single-outcome conditions...
The brain-derived neurotrophic factor receptor TrkB is critical for the acquisition but not expression of conditioned incentive valueAlexander W Johnson
Department of Psychological and Brain Sciences, Neurogenetics and Behavior Center, Johns Hopkins University, Baltimore, MD 21218, USA
Eur J Neurosci 28:997-1002. 2008....
Effects of serum response factor (SRF) deletion on conditioned reinforcementA W Johnson
Neurogenetics and Behavior Center, Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, MD, USA
Behav Brain Res 220:312-8. 2011..These results suggest a role for SRF in conditioned reinforcement, a manifestation of incentive learning that has been implicated in many aspects of adaptive and maladaptive behavior, such as substance abuse and eating disorders...
Targeted deletion of the GluR-1 AMPA receptor in mice dissociates general and outcome-specific influences of appetitive rewards on learningAlexander W Johnson
School of Psychology, Cardiff University, UK
Behav Neurosci 121:1192-202. 2007..The results support the hypothesis that GluR-1 deletion impairs the associative activation of a representation of the sensory-specific incentive motivational properties of an appetitive reward...
A selective role for neuronal activity regulated pentraxin in the processing of sensory-specific incentive valueAlexander W Johnson
Neurogenetics and Behavior Center, Johns Hopkins University, Baltimore, Maryland 21218, USA
J Neurosci 27:13430-5. 2007..These data suggest Narp has a selective role in processing sensory-specific information necessary for appropriate devaluation performance, but not in general motivational effects of reward-predictive cues on performance...
Greater effort boosts the affective taste properties of foodAlexander W Johnson
Department of Psychological and Brain Sciences, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA
Proc Biol Sci 278:1450-6. 2011....
Impaired outcome-specific devaluation of instrumental responding in mice with a targeted deletion of the AMPA receptor glutamate receptor 1 subunitAlexander W Johnson
School of Psychology, Cardiff University, Cardiff CF10 3YG, United Kingdom
J Neurosci 25:2359-65. 2005....
Narp deletion blocks extinction of morphine place preference conditioningHans S Crombag
Department of Psychological and Brain Sciences, Neurogenetics and Behavior Center, The Johns Hopkins University, Baltimore, MD, USA
Neuropsychopharmacology 34:857-66. 2009..Thus, these findings indicate that Narp plays a selective role in extinction, possibly by its effects on AMPA receptor trafficking...
The role of melanin-concentrating hormone in conditioned reward learningAndrew Sherwood
Department of Psychological and Brain Sciences, Johns Hopkins University, Ames Hall, 3400 N Charles Street, Baltimore, MD, USA
Eur J Neurosci 36:3126-33. 2012..These results suggest a role for MCH in guiding behavior based on the conditioned reinforcing value of a cue, but not on its incentive motivational value...
Role of medial prefrontal cortex Narp in the extinction of morphine conditioned place preferenceAshley M Blouin
Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
Learn Mem 20:75-9. 2013..These findings suggest that Narp in the mPFC mediates the extinction of morphine CPP...
Deficits in sensory-specific devaluation task performance following genetic deletions of cannabinoid (CB1) receptorHans S Crombag
Neurogenetics and Behavior Center, Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, Maryland 21218, USA
Learn Mem 17:18-22. 2010..These results identify a critical role for CB1 receptor in the ability of animals to represent, update, and/or use sensory-specific outcome representations to alter appetitive behaviors...
Learning processes affecting human decision making: An assessment of reinforcer-selective Pavlovian-to-instrumental transfer following reinforcer devaluationMelissa J Allman
Department of Behavioral Psychology, Kennedy Krieger Institute, Baltimore, MD, USA
J Exp Psychol Anim Behav Process 36:402-8. 2010..These results are discussed in terms of implications for understanding associative learning processes in humans and the ability of reward-paired cues to direct adaptive and maladaptive behavior...
An assessment of olfaction and responses to novelty in three strains of miceDani R Smith
Neurogenetics and Behavior Center, Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, MD 21218, USA
Behav Brain Res 201:22-8. 2009..We also separately assessed simple odor detection. Our results show that compared to the C57 mice, 129 and F1 mice showed reduced levels of exploration and odor driven novelty preference...
A pathway-specific function for different AMPA receptor subunits in amygdala long-term potentiation and fear conditioningYann Humeau
Friedrich Miescher Institute for Biomedical Research, CH 4058 Basel, Switzerland
J Neurosci 27:10947-56. 2007....
